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Competitive Position

PBPropanc Biopharma, Inc.

$1.17

+0.15 (+14.71%)

Market Cap
2.67 M
EPS
-33.19
P/E Ratio
-
Value Trade
25.91 K
SEC Financials
Q1 2026
  • Dilution Risk

    95%
  • R&D Expenses

    169.66 K


  • Total Assets

    14.33 M

  • Total Liabilities

    3.51 M

  • Equity

    9.83 M

18.18 %
Week
-37.77 %
1 Month
-53.66 %
3 Month
-75.5 %
6 Month
-100 %
5 Year
-100 %
All Time
Cash Data
Critical
  • Cash Position

    443.70 K

  • Monthly Burn

    2.13 M

  • Runway

    0 mo

  • Burn Trend

    Accelerating
  • SEC Filing

    May 14, 2026
Overview
Volume
247.09 K
52 Week Range
0.95 - 234
% held by Insiders
10.46 %
% held by Institutions
0.53 %
Enterprise Value
2.38 M
Total Shares
2.28 M
Short %
8.2 %
Float Shares
1.63 M
Company Description
HQ: 302/6 BUTLER STREET, CAMBERWEL...
Employees:2

locked

Upcoming Catalyst
Catalyst Drug/Treatment Stage Probability of Approval Description Drug Type Therapeutic Area Source
Example Drug Treatment for example condition requiring FDA review
Phase 3
-%

FDA review of the new drug application for the treatment of example condition.

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Small Molecule
Oncology
Example Drug Treatment for example condition requiring FDA review
Phase 3
-%

FDA review of the new drug application for the treatment of example condition.

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Small Molecule
Oncology
Example Drug Treatment for example condition requiring FDA review
Phase 3
-%

FDA review of the new drug application for the treatment of example condition.

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Small Molecule
Oncology
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Catalyst Timeline

Dated clinical, regulatory & corporate events for Propanc Biopharma, Inc.

61Total events
3Upcoming
4Tier-1 (high impact)
2014 – 2027Coverage

Upcoming catalysts 2

TBD
T3Manufacturing Milestone
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PRP
TBD
T2Trial Initiation
Subscribe to view catalyst details
PRP

Event history 2

TBD
PublicationPresentation
Subscribe to view catalyst details
TBD
Development Candidate NominationRec-PRPPreclinical
Subscribe to view catalyst details
Unlock the full Catalyst Timeline
Past FDA Catalysts & PDUFA Decisions
Date Drug Catalyst Stage Outcome Reaction Event Move % Best Trade %
Example Drug
Phase 3 data readout
Phase 3
0%
0%
Example Drug
Phase 3 data readout
Phase 3
0%
0%
Example Drug
Phase 3 data readout
Phase 3
0%
0%
Unlock Historical Catalyst data
Drug Pipeline Intelligence
Unlock Drug Pipeline Intelligence
Clinical Trial Results
Drug Name Indications Phase Date Trial Results Summary Title Source
Example Drug
Example indication for clinical evaluation
Phase 3
2025-12-01

The study met its primary endpoint demonstrating statistically significant improvement.

Read More

Phase 3 Study Results Announcement

Example Drug
Example indication for clinical evaluation
Phase 3
2025-12-01

The study met its primary endpoint demonstrating statistically significant improvement.

Read More

Phase 3 Study Results Announcement

Example Drug
Example indication for clinical evaluation
Phase 3
2025-12-01

The study met its primary endpoint demonstrating statistically significant improvement.

Read More

Phase 3 Study Results Announcement

Unlock Clinical Trial Results data
Inside Trades
TREND
CORPORATE INSIDERS BOUGHT SHARES WORTH 1.8M IN THE LAST 3 MONTHS
YEARLY INSIDER TRANSACTIONS
Sector Avg.
INSIDERS
SOLD
INSIDERS
BOUGHT
POSITIVE SENTIMENT Based on 22 Insiders Transactions
Unlock Inside Trades data
Hedge Funds
TREND
HEDGE FUNDS INCREASED HOLDINGS BY 200.0K SHARES IN THE LAST QUARTER
Shares Held
2040.00B1530.00B1020.00B510.00B0
Q3
2024
Q4
2024
Q1
2025
Q2
2025
HEDGE FUNDS
SOLD
HEDGE FUNDS
BOUGHT
POSITIVE SENTIMENT Based on 27 hedge funds in the last quarter
18 buying (3 new)·9 selling (1 exited)·2 unchanged
Fund Count
60%
Share Volume
25%
Conviction
15%
HedgeFund Name
( 3 )
% of Portfolio Current MV
-
Shares Owned
-
Activity
Avg Price $0

Example Capital Management

2.5 %
15.00 M
250.00 K

Example Capital Management

2.5 %
15.00 M
250.00 K

Example Capital Management

2.5 %
15.00 M
250.00 K
Unlock Hedge Funds table data
PPCB Institutional Ownership Trends
Current Insider %
5.20%
+0.00%
Current Institutional %
62.40%
+0.00%
Total Ownership
67.60%
Insider + Institutional
Data Points
1
1 Ticker(s)
Option Chain Statistics
ExpirationVolumeOpen InterestImplied Volatility CallsImplied Volatility Puts
CallsPutsPut-Call RatioCallsPutsPut-Call RatioIVOiWaIvVWaIvIVOiWaIvVWaIv
Unlock Option Chain Statistics data
Option Chain
CallsStrikePuts
Last PriceVolumeOpen InterestLast PriceVolumeOpen Interest
No data available
Unlock Option Chain data
Unlock Options Chart data
Open interest
0 600K 1.2M 1.8M Avg OI 1.00 M Open Interest
0 1 2 3 1.1 Put-Call Ratio
Today's Open Interest
1.00 M
Put-Call Ratio
1.1
Put Open Interest
480.00 K
Call Open Interest
520.00 K
Open Interest Avg (30-day)
900,000
Today vs Open Interest Avg (30-day)
11.11%
Option Volume
0 450K 900K 1.4M Avg OV 750.00 K Option Volume
0 1 2 3 0.95 Put-Call Ratio
Today's Volume
750.00 K
Put-Call Ratio
0.95
Put Volume
360.00 K
Call Volume
390.00 K
Volume Avg (30-day)
800,000
Today vs Volume Avg (30-day)
-6.25%
Company News
-PPCB
Aug 5, 2026
PPCBGeneral
▲ +14.7%today

Propanc Biopharma Completes First Tranche of $5.0 Million Share Repurchase Program

Propanc Biopharma has completed the first $500,000 tranche of its $5 million share repurchase program. The company aims to enhance shareholder value as it prepares for a Phase 1b study involving 40-45 advanced cancer patients. CEO James Nathanielsz emphasized the potential of their lead product, PRP, to transform metastatic cancer into a manageable condition.

Read more →
-PPCB
Jul 21, 2026
PPCBGeneral

Propanc Biopharma Publishes Evaluation of Recombinant Trypsinogen & Chymotrypsinogen in Peer Reviewed Journal

Propanc Biopharma has published findings on recombinant trypsinogen and chymotrypsinogen in the journal Microbial Cell Factories. This research supports the development of rec-PRP, a backup clinical compound for treating metastatic cancer. The study indicates that these proenzymes can be produced at scale, potentially leading to effective treatments with a longer shelf life. The company aims to enter clinical trials for rec-PRP in early 2027.

Read more →
-PPCB
Jul 7, 2026
PPCBPhases

Propanc Biopharma Signs MOU with Avance Clinical Pty Ltd

Propanc Biopharma has signed a Memorandum of Understanding with Avance Clinical to support the Phase 1b clinical trial of its lead candidate, PRP, aimed at treating advanced solid tumors. The collaboration emphasizes a commitment to scientific rigor and patient safety. Avance Clinical will leverage its expertise to facilitate the trial's design and execution, aiming for efficient progression through clinical phases.

Read more →
-PPCB
Jul 2, 2026
PPCBGeneral
▲ +22.9%on this newsshared move

Propanc Biopharma Initiates $5.0 Million Share Repurchase Program

Propanc Biopharma has launched a $5 million share repurchase program, starting with an initial tranche of $500,000. CEO James Nathanielsz highlighted the company's belief in the transformative potential of its lead asset, PRP, for treating metastatic cancer. The program allows for flexible share buybacks based on market conditions and reflects the company's commitment to enhancing shareholder value.

Read more →
-PPCB
Jun 16, 2026
PPCBPhases
▼ -10.2%on this news· ran to -31% by day 3

Propanc Biopharma’s CEO Tours European CDMO & Plans for GMP Production of PRP for Phase 1b, FIH Study

Propanc Biopharma's CEO, James Nathanielsz, visited a European CDMO to prepare for GMP production of PRP for a Phase 1b study targeting advanced cancer patients. The visit aimed to solidify the partnership and discuss project timelines, including pre-production and engineering runs. The company anticipates submitting a clinical trial application in Australia in 2026.

Read more →
-PPCB
Jun 11, 2026
PPCBGeneral
▲ +80%on this newsshared move

Propanc Biopharma Authorizes $5.0 Million Share Repurchase Program

Propanc Biopharma has announced a $5 million share repurchase program, reflecting its confidence in the company's intrinsic value. This decision comes as the company progresses its lead asset, PRP, towards a pivotal Phase 1b clinical trial for metastatic cancer. The FDA has granted Orphan Drug Designation for PRP, enhancing its market potential.

Read more →
-PPCB
Jun 2, 2026
PPCBGeneral

Propanc Biopharma’s CEO Attends Keynote Address, “Rejuvenation and Health: Science for an Ageing Society,” at the University of Granada, Spain

Propanc Biopharma's CEO, James Nathanielsz, attended a keynote address at the University of Granada, focusing on rejuvenation and health in an ageing society. The event featured Dr. Juan Carlos Izpisúa, a leading scientist in regenerative medicine. Propanc's ongoing research aims to develop treatments targeting age-related diseases, with their lead product PRP set to enter a Phase 1b study.

Read more →
-PPCB
May 19, 2026
PPCBPhases

Propanc Biopharma Engages European CDMO for GMP Production of PRP for Phase 1b, FIH Study in 30 – 40 Advanced Cancer Patients

Propanc Biopharma has engaged a European CDMO for GMP production of its lead asset, PRP, ahead of a Phase 1b, First-In-Human study targeting 30-40 advanced cancer patients. The therapy aims to induce differentiation in cancer cells rather than directly killing them, potentially offering a novel treatment approach. The company plans to file a clinical trial application later this year.

Read more →
-PPCB
May 14, 2026
PPCBGeneral
▼ -21.4%on this newsshared move

Propanc Biopharma Implements Reverse Stock Split to Support Continued Nasdaq Listing and Growth Plans

Propanc Biopharma has approved a 1-for-25 reverse stock split to comply with Nasdaq listing requirements. Effective May 18, 2026, the split will reduce the number of outstanding shares significantly. The company aims to enhance its market position and advance its lead product candidate, PRP, into a Phase 1b clinical study for advanced cancer patients.

Read more →
-PPCB
Mar 24, 2026
PPCBGeneral
▼ -5.9%on this news

Propanc Biopharma Executes Multi-Yr, Anti-Aging & Cancer Research Collaboration with the Universities of Jaén and Granada, Spain

Propanc Biopharma has entered a multi-year research collaboration with the Universities of Jaén and Granada in Spain, focusing on anti-aging and cancer research. This partnership aims to evaluate a senescence-modulating compound and support claims related to recently filed patents. The collaboration is expected to enhance Propanc's intellectual property and advance its lead asset, PRP, towards clinical studies.

Read more →
-PPCB
Mar 3, 2026
PPCBPhases
▼ -5.2%on this news

Propanc Biopharma’s Lead Asset PRP Shows >85% Tumor Growth Inhibition in Preclinical Pancreatic Models

Propanc Biopharma's lead asset, PRP, demonstrates over 85% tumor growth inhibition in preclinical pancreatic cancer models. The investigational therapy targets cancer stem cells and aims to improve treatment outcomes while minimizing side effects. With a Phase 1b trial slated for 2026, the company is optimistic about PRP's potential to redefine cancer care.

Read more →
-PPCB
Feb 18, 2026
PPCBGeneral

Propanc Biopharma Provides Corporate Update and Reports Half Yearly 2025/26 Results

Propanc Biopharma has provided a corporate update and reported its half-yearly financial results for 2025/26. The company has filed four provisional patent applications to enhance its intellectual property portfolio and published research on the impact of proenzymes on pancreatic cancer. Additionally, a $100 million private placement has been secured to support clinical development, with plans for a Phase 1b study of its lead asset, PRP.

Read more →
-PPCB
Feb 5, 2026
PPCBPhases
▲ +5.7%on this news

Propanc Biopharma Unveils PRP: A Game-Changing Proenzyme Therapy Poised to Challenge Standard Cancer Treatments in the $3+ Billion Pancreatic Cancer Market

Propanc Biopharma has introduced PRP, a novel proenzyme therapy aimed at treating pancreatic cancer. This therapy combines two pancreatic proenzymes and has shown promising results in preclinical studies, including significant tumor growth inhibition. PRP seeks to address the limitations of current cancer treatments by targeting cancer stem cells and minimizing side effects. The company plans to initiate a Phase 1b First-In-Human study in 2026.

Read more →
-PPCB
Jan 28, 2026
PPCBGeneral
▲ +31.2%on this news

Propanc Biopharma Accelerates IP Momentum: Files Fourth Provisional Patent Application in Just Two Months – Strengthening Global Protection for Breakthrough Proenzyme Formulations

Propanc Biopharma has filed its fourth provisional patent application in two months, focusing on innovative formulations of pancreatic proenzymes. This move aims to strengthen its patent portfolio, potentially doubling it to over 200 patents. The company is preparing for a Phase 1b study of its lead asset, PRP, which targets cancer stem cells while minimizing toxicity. CEO James Nathanielsz emphasizes the significance of these patents in securing the company's leadership in cancer treatment.

Read more →
-PPCB
Jan 20, 2026
PPCBGeneral

Propanc Biopharma Files New Provisional Patent Application for Methods of Producing Trypsinogen & Chymotrypsinogen with IP Australia

Propanc Biopharma has filed a new provisional patent application for producing synthetic versions of trypsinogen and chymotrypsinogen, aimed at treating metastatic cancer. This innovative approach could lead to a world-first therapy with extended shelf-life and global distribution capabilities. The company is optimistic about its strategic plan and ongoing research into unmet medical needs.

Read more →
-PPCB
Jan 16, 2026
PPCBPhases
▼ -10.8%on this news· ran to -24% by day 3shared move

Propanc Biopharma Explains How PRP Could Impact Pancreatic Cancer

Propanc Biopharma has provided an update on its pancreatic cancer research, focusing on its lead candidate PRP, a mixture of pancreatic proenzymes. The FDA has granted PRP Orphan Drug Designation, highlighting the urgent need for effective treatments. The company plans to initiate Phase I/II clinical trials in 2026, targeting cancer stem cells and offering a potential new therapeutic option.

Read more →
-PPCB
Jan 13, 2026
PPCBPhases

Propanc Biopharma Provides Shareholder Update

Propanc Biopharma provided a shareholder update detailing its progress in 2025 and plans for 2026. The company aims to advance its lead asset, PRP, into a Phase 1b clinical study for advanced solid tumors. Propanc is also expanding its research into additional therapeutic areas and developing a synthetic backup compound, Rec-PRP. The CEO expressed confidence in the company's strategic roadmap and potential for growth.

Read more →
-PPCB
Dec 22, 2025
PPCBPhases
▼ -8.5%on this news

Propanc Biopharma Publishes Impact of Proenzymes on Pancreatic Ductal Adenocarcinoma Fibroblasts in Peer Reviewed Journal

Propanc Biopharma has published significant findings on the effects of proenzymes on pancreatic ductal adenocarcinoma (PDAC) fibroblasts in a peer-reviewed journal. The study suggests that PRP, a treatment derived from bovine pancreatic proenzymes, may disrupt the tumor microenvironment and improve survival rates for patients. Future clinical trials are planned to further investigate PRP's efficacy as an adjunct therapy for advanced PDAC.

Read more →
-PPCB
Dec 4, 2025
PPCBPhases

Propanc Biopharma Investigates “Mesenchymal Drift” to Reverse Chronic Diseases Defined by Altos Labs

Propanc Biopharma is set to explore 'mesenchymal drift' to develop treatments for chronic diseases, including cancer and fibrosis. The company's lead candidate, PRP, may influence critical biological processes linked to these conditions. A Phase 1b study for PRP is scheduled for 2026, aiming to assess its safety and efficacy in patients with advanced solid tumors.

Read more →
-PPCB
Aug 14, 2025
PPCBGeneral
▲ +30%on this news· ran to -64% by day 1

Propanc Biopharma Announces Nasdaq Uplisting and Pricing of $4 Million Public Offering Propanc common stock expected to begin trading on Nasdaq under the symbol PPCB Melbourne, Australia / Globe Newswire /

Propanc Biopharma, Inc. has announced the pricing of an underwritten public offering of 1,000,000 shares of common stock, priced at $4.00 per share, expected to yield approximately $4 million in gross proceeds. The company has also received approval to uplist its common stock on the Nasdaq Capital Market, with trading set to commence on August 15, 2025. The funds from the offering will be used for working capital and general business purposes. This marks a significant transition from OTC trading to a more prominent exchange.

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-PPCB
Jun 24, 2019
PPCBGeneral

Propanc Biopharma Appoints Carlo Campiciano as Chief Financial Officer CFO Adds Substantial Financial, Medical Technology and Senior Exchange Experience

Biopharma Appoints Carlo Campiciano as Chief Financial Officer Adds Substantial Financial, Medical Technology and Senior Exchange Experience Australia - June 24, 2019 - Propanc Biopharma, Inc. (OTC: PPCB) ("Propanc", the "Company", "we", "our", or "us"), a biopharmaceutical co

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-PPCB
Apr 10, 2018
PPCBGeneral

Propanc Biopharma Completes Scientific Advice Meeting with MHRA Company Receives Guidance on the Investigational Medicinal Product Manufacturing Program for

Biopharma Completes Scientific Advice Meeting with MHRA Receives Guidance on the Investigational Medicinal Product Manufacturing Program for PRP. AUSTRALIA, April 10, 2018-- Propanc Biopharma Inc. (OTCQB: PPCB) ("Propanc Biopharma" or the "Company"), a clinical stage biopharma

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-PPCB
Mar 14, 2018
PPCBGeneral

Propanc Biopharma Completes Successful Reproduction Run for PRP Company Requests Scientific Advice Meeting with the MHRA (UK) to Discuss Next Steps MELBOURNE, AUSTRALIA

Biopharma Completes Successful Reproduction Run for PRP Requests Scientific Advice Meeting with the MHRA (UK) to Discuss Next Steps AUSTRALIA, March 14, 2018-- Propanc Biopharma Inc. (OTCQB: PPCB) ("Propanc Biopharma" or the "Company"), a clinical stage biopharmaceutical compa

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-PPCB
Feb 20, 2018
PPCBGeneral

Propanc Biopharma Receives Allowance of Key Patent Application in the EU Patent covers a pharmaceutical composition for treating cancer comprising trypsinogen and chymotrypsinogen within the European Union MELBOURNE, AUS

Propanc Biopharma Receives Allowance of Key Patent Application Patent covers a pharmaceutical composition for treating cancer comprising trypsinogen and chymotrypsinogen within the European Union MELBOURNE, AUSTRALIA, February 20, 2018- Propanc Biopharma Inc. (OTCQB: PPCB) ("

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-PPCB
Mar 31, 2017
PPCBGeneral

Propanc Authorizes Reverse Stock Split

Propanc Authorizes Reverse Stock Split and Corporate Name Change to Propanc Biopharma, Inc. Reverse Split and Name Change to be Effectuated AUSTRALIA, March 31, 2017-- Propanc Health Group Corporation (OTCQB: PPCH) ("Propanc" or "the Company"), an emerging healthcare company

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-PPCB
Aug 23, 2016
PPCBGeneral

Propanc Enters into Contract Manufacturing Agreement with AmatsiQBiologicals Development and Production of PRP for Human Use in First-In-Man Studies MELBOURNE, AUSTRALIA

Propanc Enters into Contract Manufacturing Agreement with AmatsiQBiologicals Development and Production of PRP for Human Use in First-In-Man MELBOURNE, AUSTRALIA, August 23, 2016 - Propanc Health Group Corporation (OTCQB: PPCH) ("Propanc" or the "Company"), an emerging health

Read more →
-PPCB
Jul 5, 2016
PPCBPhases

Propanc Receives Investment to Initiate GLP Safety Toxicology Study for PRP Set to Initiate Development and GMP manufacture of Finished Drug Product for First-In-Man Studies MELBOURNE, AUSTRALIA

Propanc Receives Investment to Initiate GLP Safety Toxicology Set to Initiate Development and GMP manufacture of Finished Drug Product for First-In-Man Studies MELBOURNE, AUSTRALIA, July 5, 2016 - Propanc Health Group Corporation (OTCQB: PPCH) ("Propanc" or "the Company"), an

Read more →
-PPCB
Nov 17, 2015
PPCBGeneral

Propanc Demonstrates Significant Anti-Tumor Efficacy in Pancreatic and Ovarian Cancer Preclinical Models; Files Patent Specifying New Therapeutic Target Dose Range MELBOURNE, AUSTRALIA, November 17 th , 2015 - Propanc He

Propanc Demonstrates Significant Anti-Tumor Efficacy in Pancreatic and Ovarian Cancer Preclinical Models; Files Patent Specifying New Therapeutic Target Dose Range MELBOURNE, AUSTRALIA, November 17th, 2015 - Propanc Health Group Corporation (OTCQB: PPCH) ("Propanc" or "the Com

Read more →
-PPCB
Sep 22, 2014
PPCBGeneral

Propanc enters into $5 million Equity Purchase Agreement with Southridge Partners MELBOURNE, AUSTRALIA

Propanc enters into $5 million Equity Purchase Agreement with MELBOURNE, AUSTRALIA, September 22, 2014 - Propanc Health Group Corporation (OTCQB:PPCH) ("Propanc" or "the Company"), an emerging healthcare company that focuses on the development of new and proprietary treatments

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-PPCB
Jun 27, 2012
PPCBGeneral

Propanc to Begin Trading on the OTC Bulletin Board Under the Symbol

Propanc to Begin Trading on the OTC Bulletin Board Under the Symbol PPCH MELBOURNE, Australia, June 27, 2012 - Propanc Health Group Corporation (OTCBB: PPCH), a developmental stage healthcare company focused on the development of new cancer treatments for patients with solid tum

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