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Opko Health Inc.

$1.41

+0.02 (+1.08%)

B 74Pipeline Score Undervalued Biotech · Commercial
Market Cap
880.52 M
EPS
-0.30
P/E Ratio
-3.84 $
Value Trade
6.78 M
SEC Financials
Q1 2026
  • Dilution Risk

    15%
  • Revenue

    124.20 M

  • R&D Expenses

    29.20 M

  • Operating CF

    -19.31 M


  • Total Assets

    1.86 B

  • Total Liabilities

    652.19 M

  • Equity

    1.20 B

  • D/E Ratio

    12,345

%
Week
%
1 Month
%
3 Month
%
6 Month
%
5 Year
%
All Time
Cash Data
Healthy
  • Cash Position

    331.86 M

  • Monthly Burn

    6.44 M

  • Runway

    50.2 mo

  • Burn Trend

    Decelerating
  • SEC Filing

    Apr 28, 2026
Overview
Volume
613.23 K
52 Week Range
1.10 - 1.60
% held by Insiders
50.3 %
% held by Institutions
28.31 %
Enterprise Value
908.23 M
Total Shares
758.89 M
Short %
10.01 %
Float Shares
330.12 M
Company Description
HQ: 4400 BISCAYNE BLVD., MIAMI, FL...
Employees:2,275

locked

Upcoming Catalyst
Catalyst Drug/Treatment Stage Probability of Approval Description Drug Type Therapeutic Area Source
Oxyntomodulin (dual GLP-1/glucagon analog) Metabolic and fibrotic disorders
Phase 1
Peptides
Endocrine System
Oxyntomodulin (dual GLP-1/glucagon analog) Metabolic and fibrotic disorders
Phase 1
Peptides
Endocrine System
Oxyntomodulin (dual GLP-1/glucagon analog) Metabolic and fibrotic disorders
Phase 1
Peptides
Endocrine System
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Drug Pipeline Intelligence
B74
Pipeline Score
$13.2B
Pipeline Value
Undervalued
Valuation Signal
22
Drugs Scored
15.0x
rNPV / MCap
Top 96%
Micro Cap
(rank 37 of 905)
Percentile Rank
Opko Health Inc. holds a solid B-grade pipeline (74/100), with $52.0B risk-adjusted pipeline value, led by CTAP101 30 μg in Chronic Kidney Disease (Phase 3).
Showing 1 of 1 assets
DrugIndicationPhaseNCT IDPTRSrNPVStatusEnrollmentVelocityDesignCompletionML SignalLast Change
CTAP101 30 μg
Small molecule
Chronic Kidney DiseasePhase 3NCT0170407960% $14.7B COMPLETED 429 - -Sep 1, 2014 -Jan 13, 2025
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Clinical Trial Results
Drug Name Indications Phase Date Trial Results Summary Title Source
Example Drug
Example indication for clinical evaluation
Phase 3
2025-12-01
Example Drug
Example indication for clinical evaluation
Phase 3
2025-12-01
Example Drug
Example indication for clinical evaluation
Phase 3
2025-12-01
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Inside Trades
TREND
CORPORATE INSIDERS BOUGHT SHARES WORTH 1.8M IN THE LAST 3 MONTHS
YEARLY INSIDER TRANSACTIONS
Sector Avg.
INSIDERS
SOLD
INSIDERS
BOUGHT
POSITIVE SENTIMENT Based on 22 Insiders Transactions
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Hedge Funds
TREND
HEDGE FUNDS INCREASED HOLDINGS BY 200.0K SHARES IN THE LAST QUARTER
Shares Held
2040.00B1530.00B1020.00B510.00B0
Q3
2024
Q4
2024
Q1
2025
Q2
2025
HEDGE FUNDS
SOLD
HEDGE FUNDS
BOUGHT
POSITIVE SENTIMENT Based on 27 hedge funds in the last quarter
18 buying (3 new)·9 selling (1 exited)·2 unchanged
Fund Count
60%
Share Volume
25%
Conviction
15%
HedgeFund Name
( 3 )
% of Portfolio Current MV
-
Shares Owned
-
Activity
Avg Price $0

Example Capital Management

2.5 %
15.00 M
250.00 K

Example Capital Management

2.5 %
15.00 M
250.00 K

Example Capital Management

2.5 %
15.00 M
250.00 K
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Opko Health Inc. (OPK) Analyst Ratings & Price Targets
Symbol
Firm
Rating
Action
Price Target
Upside
date
OPK
Example Securities
Buy
Initiated
$150.00
+25%
2026-01-15
OPK
Example Securities
Buy
Initiated
$150.00
+25%
2026-01-15
OPK
Example Securities
Buy
Initiated
$150.00
+25%
2026-01-15
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OPK Stock Forecast & Analyst Consensus
BUY
Analyst Ratings
Buy65.0%
Hold25.0%
Sell10.0%
Price Target Trend
Average$24.00
Low$18.00
High$32.00
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OPK Institutional Ownership Trends
Current Insider %
5.20%
+0.00%
Current Institutional %
62.40%
+0.00%
Total Ownership
67.60%
Insider + Institutional
Data Points
1
1 Ticker(s)
Option Chain Statistics
ExpirationVolumeOpen InterestImplied Volatility CallsImplied Volatility Puts
CallsPutsPut-Call RatioCallsPutsPut-Call RatioIVOiWaIvVWaIvIVOiWaIvVWaIv
2026-06-180 0.00 0 0 - - - - - -
2026-06-180 0.00 0 0 - - - - - -
2026-06-180 0.00 0 0 - - - - - -
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Option Chain
CallsStrikePuts
Last PriceVolumeOpen InterestLast PriceVolumeOpen Interest
No data available
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Open interest
0 600K 1.2M 1.8M Avg OI 1.00 M Open Interest
0 1 2 3 1.1 Put-Call Ratio
Today's Open Interest
1.00 M
Put-Call Ratio
1.1
Put Open Interest
480.00 K
Call Open Interest
520.00 K
Open Interest Avg (30-day)
900,000
Today vs Open Interest Avg (30-day)
11.11%
Option Volume
0 450K 900K 1.4M Avg OV 750.00 K Option Volume
0 1 2 3 0.95 Put-Call Ratio
Today's Volume
750.00 K
Put-Call Ratio
0.95
Put Volume
360.00 K
Call Volume
390.00 K
Volume Avg (30-day)
800,000
Today vs Volume Avg (30-day)
-6.25%
Company News
-OPK
Jun 15, 2026
OPKPhases

Preclinical Data for OPKO Biologics' OPK8801001 in Acromegaly Presented at ENDO 2026

OPKO Biologics presented promising preclinical data for OPK8801001 at ENDO 2026, indicating its potential as a long-acting treatment for acromegaly. The data demonstrated significant suppression of IGF-1 levels, suggesting a weekly dosing alternative to current daily therapies. The findings reinforce OPKO's commitment to developing innovative treatment options for patients with endocrine disorders.

Read more →
-OPK
Apr 30, 2026
OPKGeneral

BioReference® Launches BioReference Direct™, Expanding Access to Consumer-Initiated Diagnostic Testing Through a Fully Integrated Digital Platform

BioReference Health LLC has launched BioReference Direct, a digital platform that allows consumers to access laboratory testing directly. This initiative aims to enhance patient-driven healthcare by providing a seamless online experience for selecting tests. The platform includes various health panels and an at-home STI test in collaboration with Abbott, promoting early detection and proactive health management.

Read more →
-OPK
Apr 29, 2026
OPKGeneral

OPKO Health Reports First Quarter 2026 Business Highlights and Financial Results

OPKO Health, Inc. reported its business highlights and financial results for the first quarter of 2026. The company reaffirmed its financial guidance for the year and scheduled a conference call to discuss these results. However, the report included cautionary forward-looking statements regarding product development and regulatory challenges.

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-OPK
Feb 27, 2026
OPKConferences/Events

OPKO Health to Participate in the Jefferies Biotech on the Beach Summit

OPKO Health, Inc. will participate in the Jefferies Biotech on the Beach Summit on March 10-11, 2026, at 1 Hotel South Beach in Miami. The company plans to hold one-on-one meetings with registered investors on March 11. This engagement aims to strengthen investor relations and showcase OPKO's biopharmaceutical and diagnostics expertise.

Read more →
-OPK
Feb 12, 2026
OPKConferences/Events

OPKO Health to Report Fourth Quarter 2025 Financial Results on February 26

OPKO Health, Inc. plans to report its financial results for Q4 2025 on February 26, 2026. The announcement includes a conference call where senior management will discuss the results and provide financial guidance. Participants can pre-register for easier access to the call, which will also be available via webcast.

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-OPK
Feb 4, 2026
OPKGeneral

OPKO Health and Entera Bio Expand Partnership to Advance First-in-Class Oral Long Acting PTH Tablet for Patients with Hypoparathyroidism

OPKO Health and Entera Bio have expanded their partnership to develop a first-in-class oral long-acting PTH tablet for hypoparathyroidism. The companies plan to file an IND application with the FDA in late 2026, following promising preclinical data. This collaboration aims to provide a more convenient treatment option for patients, moving away from daily injections.

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Competitive Position
How OPK ranks across every disease it competes in
Competitive Position is a premium feature
See how OPK ranks against every competitor across each disease it develops in: phase, best drug, trials and likelihood of approval.
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