Recent Updates
Recently added Catalysts

Ondansetron

Phase 1

Nausea | Small molecule | Other |Novartis AG|Last Updated: Mar 28, 2017

Success Probability
Approval Probability 71%
TA Base Rate26%
Adjusted LOA41%
ML RiskLOW_RISK
Premium
Market & Valuation
rNPV $3.2B
Market Size $9.4B
Revenue Basis $1.6B
Competitors 6
Premium
Trial Design
RandomizedACTIVE_CONTROLLED
Total Trials2
Total Enrollment52
FDA Designations
No designations recorded
Clinical Trials (2)
NCT IDTitlePhaseStatusEnrollmentVelocityDesignStartCompletionLast UpdatedSitesCountries
NCT00946387To Demonstrate the Relative Bioavailability Study of Ondansetron HCl 24 mg Tablets Under Fasting ConditionsPHASE1 COMPLETED 26Sep 1, 2004Sep 1, 2004Mar 28, 2017 -
NCT00947128To Demonstrate the Relative Bioavailability Study of Ondansetron HCl 24 mg Tablets Under Non-Fasting ConditionsPHASE1 COMPLETED 26Sep 1, 2004Oct 1, 2004Mar 28, 2017 -
Unlock Drug Trial Details
Study Endpoints
Primary Endpoints
Bioequivalence based on AUC and Cmax
9 days
Unlock Study Endpoints
Study Design & Arms
AllocationRANDOMIZED
MaskingNONE
ModelSINGLE_GROUP
PurposeTREATMENT
Treatment Arms
ArmTypeDescription
1EXPERIMENTALOndansetron HCl 24 mg Tablets (Sandoz, Inc.)
2ACTIVE_COMPARATORZofran (Ondansetron HCl) 24 mg Tablets (GlaxoSmithKline)
Interventions
NameTypeDescription
Ondansetron HCl 24 mg Tablets (Sandoz, Inc.)DRUG -
Zofran (Ondansetron HCl) 24 mg Tablets (GlaxoSmithKline)DRUG -
Unlock Study Design Details
Eligibility Criteria
Age Range22 Years — 58 Years
SexALL
Healthy VolunteersYes

Inclusion Criteria: * No clinically significant abnormal finding on physical exam, medical history, or clinical laboratory results on screening. Exclusion Criteria: * Positive test results for HIV or hepatitis B or C. * Treatment for drug or alcohol dependence.

Unlock Eligibility Criteria