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Fixed-Dose Combination

Phase 1

Healthy Volunteer Study | Small molecule | Other |NewAmsterdam Pharma Company N.V.|Last Updated: Jun 4, 2024

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Trial Design

UNCONTROLLED
Total Trials1
Total Enrollment28

FDA Designations

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Clinical trial landscape

Fixed-Dose Combination · 1 trial · 1 indication

Phase 1 1
NCT06050291Investigating the Effect of Food on the Bioavailability of a Fixed Dose Combination of Obicetrapib and EzetimibeHealthy Volunteer Study
COMPLETED28 Analytics
PHASE1COMPLETED
Investigating the Effect of Food on the Bioavailability of a Fixed Dose Combination of Obicetrapib and Ezetimibe
Healthy Volunteer StudyUnlock trial analytics

Study Design & Arms

Interventions

NameTypeDescription
Fixed-Dose Combination (FDC) TabletDRUGObicetrapib/Ezetimibe FDC tablet
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Frequently asked questions about Fixed-Dose Combination

What is the Fixed-Dose Combination drug used for?

The Fixed-Dose Combination is an investigational small molecule being studied in healthy volunteers. It is being evaluated in a Phase 1 clinical trial to investigate the effect of food on its bioavailability. The drug combines obicetrapib and ezetimibe in a single fixed-dose formulation.

Who is developing the Fixed-Dose Combination?

NewAmsterdam Pharma Company N.V. (ticker: NAMS) is developing the Fixed-Dose Combination. The company is conducting a Phase 1 clinical trial of this investigational drug, which combines obicetrapib and ezetimibe, in healthy volunteers.

What phase is the Fixed-Dose Combination in?

The Fixed-Dose Combination is in Phase 1 clinical development. It is an investigational drug and has not been approved by regulatory authorities. A Phase 1 trial has been completed, with no active trials currently ongoing.

What clinical trials is the Fixed-Dose Combination in?

The Fixed-Dose Combination has one completed Phase 1 trial, NCT06050291, titled "Investigating the Effect of Food on the Bioavailability of a Fixed Dose Combination of Obicetrapib and Ezetimibe." This trial enrolled 28 healthy volunteers and was uncontrolled, meaning it did not use a comparator group.

Is the Fixed-Dose Combination the same as obicetrapib and ezetimibe?

The Fixed-Dose Combination is a single formulation that contains both obicetrapib and ezetimibe. It is being studied to assess how food affects the bioavailability of this combined product, as opposed to the individual components taken separately.