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tenecteplase

Phase 2

Myocardial Infarction | Small molecule | Cardiovascular |Eli Lilly and Company|Last Updated: May 19, 2017

Success Probability

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Market & Valuation

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Trial Design

RandomizedUNCONTROLLEDBiomarker
Total Trials1
Total Enrollment300

FDA Designations

No designations recorded

Clinical trial landscape

tenecteplase · 1 trial · 1 indication

Phase 2 1
NCT00121446Which Therapy for Acute Heart Attacks? (The WEST Study)Myocardial Infarction
COMPLETED300 Analytics
PHASE2COMPLETED
Which Therapy for Acute Heart Attacks? (The WEST Study)
Myocardial InfarctionUnlock trial analytics

Study Endpoints

Primary Endpoints

composite of 6 elements defined by: death
recurrent myocardial infarction
heart failure
cardiogenic shock
refractory ischemia
major ventricular arrhythmia

Secondary Endpoints

90 and 180 minute ECG ST resolution
QRS determined infarct size at discharge/day 7
CK infarct size determined by area under the curve or peak CK-MB
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Study Design & Arms

AllocationRANDOMIZED
MaskingNONE
ModelPARALLEL
PurposeTREATMENT

Interventions

NameTypeDescription
tenecteplaseDRUG -
enoxaparinDRUG -
clopidogrelDRUG -
percutaneous coronary interventionPROCEDURE -
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Eligibility Criteria

Age Range18 Years to N/A
SexALL
Healthy VolunteersNo
Study Sites16

Inclusion Criteria: * Male or non-pregnant female patients aged \>18 years * Patients with symptoms presumed secondary to STEMI lasting at least 20 minutes and accompanied by ECG evidence \>2 mm of ST elevation in 2 or more contiguous precordial leads or in 2 or more limb leads;or \> 1mm ST elevati...

Countries:Canada
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Frequently asked questions about tenecteplase

What is tenecteplase used for?

Tenecteplase is used for myocardial infarction, commonly known as a heart attack. It is being investigated as a treatment for this condition in a clinical trial setting. The drug is currently in Phase 2 development for this cardiovascular indication.

Who makes tenecteplase?

Tenecteplase is being developed by Eli Lilly and Company, a pharmaceutical company listed on the stock exchange under the ticker symbol LLY. The company is conducting clinical research to evaluate the drug's potential in treating myocardial infarction.

What phase is tenecteplase in?

Tenecteplase is in Phase 2 clinical development for myocardial infarction. It is an investigational drug, meaning it has not yet been approved by regulatory authorities. The drug is being studied to assess its safety and efficacy in patients with this condition.

What clinical trials is tenecteplase in?

Tenecteplase is associated with one completed clinical trial, NCT00121446, titled 'Which Therapy for Acute Heart Attacks? (The WEST Study)'. This Phase 2 trial enrolled 300 participants with myocardial infarction in Canada. The study was not double-blinded and did not use a control group.

Is tenecteplase a small molecule?

Yes, tenecteplase is classified as a small molecule therapeutic. It is being developed as a treatment for myocardial infarction, a cardiovascular condition. The drug is currently in Phase 2 clinical trials, with one completed study involving 300 patients.