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VXCO-102

Phase 1

EBV | Monoclonal antibody | Other |Eli Lilly and Company|Last Updated: Apr 29, 2026

Development status

Highest phase Phase 1
Registered trials 1 across 1 sponsor since Apr 2026

Success Probability

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Market & Valuation

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Trial Design

RandomizedDouble-BlindPLACEBO_CONTROLLEDDMC
Total Trials1
Total Enrollment45

FDA Designations

No designations recorded

Clinical trial landscape

VXCO-102 · 1 trial · 1 indication

Phase 1 1
NCT07557602mRNA Vaccine Targeting Epstein-Barr Virus (EBV) in Healthy Young AdultsEBV
NOT YET_RECRUITING45 Analytics
PHASE1NOT YET_RECRUITING
mRNA Vaccine Targeting Epstein-Barr Virus (EBV) in Healthy Young Adults
EBVUnlock trial analytics

Study Endpoints

Primary Endpoints

Number of Participants with Solicited Local and Systemic Reactions
7 days after each product administration
Number of Participants with Unsolicited Adverse Events
Up to 28 days after each product administration
Number of Participants with Serious Adverse Events (SAEs) including Suspected Unexpected Serious Adverse Reactions (SUSARs) and Adverse Events of Special Interest (AESIs)
Day 1 to end of study (Day 357)

Secondary Endpoints

Rate of neutralizing antibody response
Day 1 and 85
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Study Design & Arms

AllocationRANDOMIZED
MaskingQUADRUPLE
ModelSEQUENTIAL
PurposePREVENTION

Treatment Arms

ArmTypeDescription
Group 1EXPERIMENTALDose 1 - VXCO-102 administered IM by needle and syringe at Day 1 and Week 8
Group 2EXPERIMENTALDose 2 - VXCO-102 administered IM by needle and syringe at Day 1 and Week 8
Group 3EXPERIMENTALDose 3 - VXCO-102 administered IM by needle and syringe at Day 1 and Week 8
Group 4PLACEBO_COMPARATORSodium Chloride administered IM by needle and syringe at Day 1 and Week 8

Interventions

NameTypeDescription
VXCO-102BIOLOGICALSterile liquid for injection
PlaceboBIOLOGICAL0.9% sodium chloride (BP grade)
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Eligibility Criteria

Age Range18 Years to 25 Years
SexALL
Healthy VolunteersYes
Study Sites2

Inclusion Criteria: * Aged 18 to 25 years, inclusive * Healthy per medical assessment based on self-reported medical history, physical examination, vital signs, and laboratory assessment Exclusion Criteria: * Self-reported or medically-documented significant medical or psychiatric condition that ...

Countries:Australia
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Frequently asked questions about VXCO-102

What is VXCO-102?

VXCO-102 is an investigational monoclonal antibody being developed by Eli Lilly and Company for Epstein-Barr virus, or EBV. It is in Phase 1 clinical development. Because it is still being studied in clinical trials, VXCO-102 is not an approved therapy and is not yet available for general use.

What is VXCO-102 used for in EBV?

VXCO-102 is being studied for Epstein-Barr virus, or EBV. The single registered Phase 1 trial is described as an mRNA vaccine targeting EBV in healthy young adults, conducted in Australia. The trial is not yet recruiting and is designed to enroll 45 participants aged 18 years and older.

Who makes VXCO-102?

VXCO-102 is being developed by Eli Lilly and Company, which trades on the New York Stock Exchange under the ticker LLY. Eli Lilly is the sponsor of the Phase 1 trial evaluating VXCO-102 in Epstein-Barr virus, and no other developer or partner is identified for this asset.

What phase is VXCO-102 in?

VXCO-102 is in Phase 1 clinical development. One Phase 1 trial has been registered for the asset, and it is currently active but not yet recruiting. No Phase 2 or later studies have been registered, and the program has not reported any completed trials to date.

What clinical trials is VXCO-102 in?

VXCO-102 is being evaluated in one registered Phase 1 trial, NCT07557602, titled mRNA Vaccine Targeting Epstein-Barr Virus (EBV) in Healthy Young Adults. The trial is not yet recruiting, is placebo controlled and double blinded, and plans to enroll 45 participants in Australia.

Is VXCO-102 approved by the FDA?

VXCO-102 is not approved. It is an investigational monoclonal antibody in Phase 1 clinical development for Epstein-Barr virus, and its only registered trial, NCT07557602, has not yet begun recruiting. Approval status would only change if the program advances through later-stage trials and regulatory review.