Recent Updates
Recently added Catalysts

Peresolimab

Phase 1

Healthy | Small molecule | Other |Eli Lilly and Company|Last Updated: Jan 29, 2024

Success Probability
Approval Probability 71%
TA Base Rate26%
Adjusted LOA41%
ML RiskLOW_RISK
Premium
Market & Valuation
rNPV $3.2B
Market Size $9.4B
Revenue Basis $1.6B
Competitors 6
Premium
Trial Design
CONTROLLEDBiomarker
Total Trials1
Total Enrollment57
FDA Designations
No designations recorded
Clinical Trials (1)
NCT IDTitlePhaseStatusEnrollmentVelocityDesignStartCompletionLast UpdatedSitesCountries
NCT05959109A Relative Bioavailability Study of Peresolimab (LY3462817) Formulations in Healthy ParticipantsPHASE1 COMPLETED 57Jul 21, 2023Jan 11, 2024Jan 29, 20241 United States
Unlock Drug Trial Details
Study Endpoints
Primary Endpoints
Pharmacokinetics (PK): Maximum Concentration (Cmax) of Peresolimab
Predose up to 85 days postdose

PK: Cmax of Peresolimab

PK: Area Under the Plasma Concentration Versus Time Curve from Zero to T, Last Time Point (AUC[0-tlast]) of Peresolimab
Predose up to 85 days postdose

PK: AUC\[0-tlast\] of Peresolimab

PK: Area Under the Plasma Concentration Versus Time Curve From Zero to Infinity (AUC[0-∞]) of Peresolimab
Predose up to 85 days postdose

PK: AUC(0-∞) of Peresolimab

Unlock Study Endpoints
Study Design & Arms
AllocationNON_RANDOMIZED
MaskingNONE
ModelPARALLEL
PurposeBASIC_SCIENCE
Treatment Arms
ArmTypeDescription
Peresolimab (Test 1)EXPERIMENTALPeresolimab administered subcutaneously (SC).
Peresolimab (Test 2)EXPERIMENTALPeresolimab administered SC.
Peresolimab (Test 3)EXPERIMENTALPeresolimab administered SC.
Peresolimab (Reference)EXPERIMENTALPeresolimab administered SC.
Interventions
NameTypeDescription
PeresolimabDRUGAdministered SC
Unlock Study Design Details
Eligibility Criteria
Age Range18 Years — 65 Years
SexALL
Healthy VolunteersYes
Study Sites1

Inclusion Criteria: * Male and female participants who are overtly healthy as determined by medical history, physical examination, and other screening procedures * A minimum body weight of 45 kilograms and body mass index (BMI) between 18.0 and 32.0 kilograms per meter squared (kg/m²), inclusive, a...

Countries:United States
Unlock Eligibility Criteria