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LY900020

Phase 1

Undisclosed | Small molecule | Other |Eli Lilly and Company|Trials Updated: Mar 3, 2020

LY900020 development status

Highest phase Phase 1
Registered trials 1 across 1 sponsor since Aug 2019

Success Probability

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Market & Valuation

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Trial Design

RandomizedACTIVE_CONTROLLED
Total Trials1
Total Enrollment32

FDA Designations

No designations recorded

LY900020 clinical trials

LY900020 · 1 trial · 1 indication

Phase 1 1
NCT04047940A Study of LY900020 in Healthy Chinese ParticipantsHealthy
COMPLETED32 Analytics
PHASE1COMPLETED
A Study of LY900020 in Healthy Chinese Participants
HealthyUnlock trial analytics

Study Endpoints

Primary Endpoints

Pharmacokinetics (PK): Area Under the Concentration Versus Time Curve (AUC) of LY900020
Predose through 72 hours postdose on Day 4 in each study arm

PK: AUC of LY900020

PK: Maximum Observed Drug Concentration (Cmax) of LY900020
Predose through 72 hours postdose on Day 4 in each study arm

PK: Cmax of LY900020

Secondary Endpoints

PK: Time to Maximum Observed Drug Concentration (tmax) of LY900020
Predose through 72 hours postdose on Day 4 in each study arm
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Study Design & Arms

AllocationRANDOMIZED
MaskingNONE
ModelCROSSOVER
PurposeBASIC_SCIENCE

Treatment Arms

ArmTypeDescription
LY900020 Formulation 1EXPERIMENTALLY900020 Formulation 1 administered orally
LY900020 Formulation 2EXPERIMENTALLY900020 Formulation 2 administered orally
LY900020 Formulation 3EXPERIMENTALLY900020 Formulation 3 administered orally
Reference DrugsACTIVE_COMPARATORMetformin XR, atorvastatin, and valsartan administered orally

Interventions

NameTypeDescription
LY900020DRUGAdministered orally
Metformin XRDRUGAdministered orally
AtorvastatinDRUGAdministered orally
ValsartanDRUGAdministered orally
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Eligibility Criteria

Age Range21 Years to 70 Years
SexALL
Healthy VolunteersYes
Study Sites1

Inclusion Criteria: * Overtly healthy male or a female (not pregnant and agreeable to take birth control measures until study completion) * Have a body mass index (BMI) of 18.5 to 35 kilogram per square meter (kg/m²), inclusive, at screening * Have normal blood pressure, pulse rate, electrocardiogr...

Countries:Singapore
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Frequently asked questions about LY900020

What is LY900020?

LY900020 is an investigational small molecule being developed by Eli Lilly and Company. It has been studied in a Phase 1 clinical trial in healthy Chinese participants. The specific therapeutic indication for LY900020 has not been disclosed.

Who is developing LY900020?

LY900020 is being developed by Eli Lilly and Company, which trades on the New York Stock Exchange under the ticker LLY. Lilly is the sponsor of the clinical program for this investigational small molecule.

What phase is LY900020 in?

LY900020 is in Phase 1 clinical development. One Phase 1 trial has been completed, and no active trials are currently listed. The program remains investigational and has not been approved by the FDA.

What clinical trials is LY900020 in?

LY900020 has been evaluated in one completed Phase 1 trial, NCT04047940, titled A Study of LY900020 in Healthy Chinese Participants. The trial enrolled 32 healthy volunteers in Singapore, was randomized and active-controlled, and included participants aged 21 years and older.

Is LY900020 FDA approved?

No. LY900020 is an investigational drug in Phase 1 clinical development and has not been approved by the FDA. It has completed one Phase 1 trial in healthy Chinese participants, and no active trials are currently listed.