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LY900020

Phase 1

Healthy | Small molecule | Other |Eli Lilly and Company|Last Updated: Mar 3, 2020

Success Probability

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Market & Valuation

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Trial Design

RandomizedACTIVE_CONTROLLED
Total Trials1
Total Enrollment32

FDA Designations

No designations recorded

Clinical trial landscape

LY900020 · 1 trial · 1 indication

Phase 1 1
NCT04047940A Study of LY900020 in Healthy Chinese ParticipantsHealthy
COMPLETED32 Analytics
PHASE1COMPLETED
A Study of LY900020 in Healthy Chinese Participants
HealthyUnlock trial analytics

Study Endpoints

Primary Endpoints

Pharmacokinetics (PK): Area Under the Concentration Versus Time Curve (AUC) of LY900020
Predose through 72 hours postdose on Day 4 in each study arm

PK: AUC of LY900020

PK: Maximum Observed Drug Concentration (Cmax) of LY900020
Predose through 72 hours postdose on Day 4 in each study arm

PK: Cmax of LY900020

Secondary Endpoints

PK: Time to Maximum Observed Drug Concentration (tmax) of LY900020
Predose through 72 hours postdose on Day 4 in each study arm
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Study Design & Arms

AllocationRANDOMIZED
MaskingNONE
ModelCROSSOVER
PurposeBASIC_SCIENCE

Treatment Arms

ArmTypeDescription
LY900020 Formulation 1EXPERIMENTALLY900020 Formulation 1 administered orally
LY900020 Formulation 2EXPERIMENTALLY900020 Formulation 2 administered orally
LY900020 Formulation 3EXPERIMENTALLY900020 Formulation 3 administered orally
Reference DrugsACTIVE_COMPARATORMetformin XR, atorvastatin, and valsartan administered orally

Interventions

NameTypeDescription
LY900020DRUGAdministered orally
Metformin XRDRUGAdministered orally
AtorvastatinDRUGAdministered orally
ValsartanDRUGAdministered orally
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Eligibility Criteria

Age Range21 Years to 70 Years
SexALL
Healthy VolunteersYes
Study Sites1

Inclusion Criteria: * Overtly healthy male or a female (not pregnant and agreeable to take birth control measures until study completion) * Have a body mass index (BMI) of 18.5 to 35 kilogram per square meter (kg/m²), inclusive, at screening * Have normal blood pressure, pulse rate, electrocardiogr...

Countries:Singapore
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Frequently asked questions about LY900020

What is LY900020?

LY900020 is an investigational small molecule being developed by Eli Lilly and Company. It is currently in Phase 1 clinical development. The drug has been studied in healthy participants, and its therapeutic area is classified as Other. As of now, it is not approved and remains in clinical trials.

What is LY900020 used for?

LY900020 is being studied for use in healthy participants. The completed Phase 1 trial evaluated the drug in healthy Chinese participants. Its specific therapeutic indication has not been established, and it is in early-stage clinical development to assess safety and tolerability.

Who makes LY900020?

LY900020 is developed by Eli Lilly and Company, a pharmaceutical company listed on the stock exchange under the ticker LLY. The company is conducting clinical trials to evaluate the drug's safety and pharmacokinetics in healthy volunteers.

What phase is LY900020 in?

LY900020 is in Phase 1 clinical development. A Phase 1 trial has been completed, and the drug is still investigational. It has not been approved by regulatory authorities, and further clinical studies would be needed to assess its safety and efficacy.

What clinical trials is LY900020 in?

LY900020 has one completed clinical trial, NCT04047940, titled "A Study of LY900020 in Healthy Chinese Participants." This Phase 1 study enrolled 32 participants in Singapore, with a minimum age of 21 years, and included both sexes. The trial was active-controlled and randomized.

Is LY900020 the same as other drugs?

LY900020 is a unique investigational drug candidate developed by Eli Lilly and Company. No alternative names have been reported for this compound. It is a small molecule in early clinical development, and its mechanism of action has not been disclosed in available information.