Recent Updates
Recently added Catalysts

LY3200327

Phase 1

Healthy | Small molecule | Other |Eli Lilly and Company|Last Updated: Sep 12, 2016

Success Probability

Subscribe to view

Market & Valuation

Subscribe to view

Trial Design

RandomizedDouble-BlindPLACEBO_CONTROLLED
Total Trials1
Total Enrollment52

FDA Designations

No designations recorded

Clinical trial landscape

LY3200327 · 1 trial · 1 indication

Phase 1 1
NCT02595736A Study of LY3200327 in Healthy ParticipantsHealthy
COMPLETED52 Analytics
PHASE1COMPLETED
A Study of LY3200327 in Healthy Participants
HealthyUnlock trial analytics

Study Endpoints

Primary Endpoints

Number of Participants with One or More Serious Adverse Event(s) (SAEs) Considered by the Investigator to be Related to Study Drug Administration
Baseline to study completion (approximately 12 weeks)

Secondary Endpoints

Pharmacokinetics (PK): Maximum Concentration (Cmax) of LY3200327
Pre-dose up to 84 days post dose
Pharmacokinetics (PK): Area Under the Concentration Versus Time Curve (AUC) of LY3200327
Pre-dose up to 84 days post dose
Unlock Study Endpoints

Study Design & Arms

AllocationRANDOMIZED
MaskingDOUBLE
ModelPARALLEL
PurposeBASIC_SCIENCE

Treatment Arms

ArmTypeDescription
Placebo (SC)PLACEBO_COMPARATORSingle subcutaneous (SC) dose of placebo
LY3200327 (SC)EXPERIMENTALSingle escalating subcutaneous (SC) dose of LY3200327
LY3200327 (IV)EXPERIMENTALSingle intravenous (IV) dose of LY3200327
Placebo (IV)PLACEBO_COMPARATORSingle intravenous (IV) dose of placebo

Interventions

NameTypeDescription
Placebo (SC)DRUGAdministered SC
LY3200327 (SC)DRUGAdministered SC
LY3200327 (IV)DRUGAdministered IV
Placebo (IV)DRUGAdministered IV
Unlock Study Design Details

Eligibility Criteria

Age Range18 Years to 65 Years
SexALL
Healthy VolunteersYes
Study Sites1

Inclusion Criteria: * At the time of initial screening, in general good health * First-generation healthy Japanese (age 20 to 65 years) will be included Exclusion Criteria: * Pregnancy or breastfeeding during the study * Chronic infection * Treatment with prohibited medications

Countries:United States
Unlock Eligibility Criteria

Frequently asked questions about LY3200327

What is LY3200327?

LY3200327 is an investigational small molecule being developed by Eli Lilly and Company. It is currently in Phase 1 clinical development for use in healthy participants. The drug has been studied in a completed clinical trial, but it is not yet approved and remains under investigation.

What is LY3200327 used for?

LY3200327 is being studied for use in healthy participants. The completed Phase 1 trial evaluated the drug in healthy volunteers to assess its safety and tolerability. It is not approved for any specific medical condition and is still in early clinical development.

Who makes LY3200327?

LY3200327 is being developed by Eli Lilly and Company, a pharmaceutical company traded on the New York Stock Exchange under the ticker symbol LLY. The company is conducting clinical research on this investigational small molecule drug.

What phase is LY3200327 in?

LY3200327 is in Phase 1 clinical development. A Phase 1 trial has been completed, and the drug remains investigational. It has not been approved by regulatory authorities and is still undergoing clinical evaluation.

What clinical trials is LY3200327 in?

LY3200327 has one completed clinical trial, identified as NCT02595736, titled "A Study of LY3200327 in Healthy Participants." This Phase 1 study enrolled 52 participants in the United States and was a randomized, double-blind, placebo-controlled trial.

Is LY3200327 the same as any other drug?

LY3200327 is the primary name for this investigational drug. No alternative names have been established in the available clinical trial information. It is being studied under this identifier in the completed Phase 1 trial.