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LY2624587

Phase 1

Metastatic Cancer | Small molecule | Oncology |Eli Lilly and Company|Last Updated: Jan 24, 2012

Success Probability

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Market & Valuation

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Trial Design

UNCONTROLLED
Total Trials1
Total Enrollment56

FDA Designations

No designations recorded

Clinical trial landscape

LY2624587 · 1 trial · 1 indication

Phase 1 1
NCT01139788A Study of LY2624587 in Patients With Advanced CancerMetastatic Cancer
COMPLETED56 Analytics
PHASE1COMPLETED
A Study of LY2624587 in Patients With Advanced Cancer
Metastatic CancerUnlock trial analytics

Study Endpoints

Primary Endpoints

Recommended dose for Phase 2 studies
Baseline to study completion

Secondary Endpoints

Number of participants with clinically significant effects
Baseline to cycle 12
Radiological tumor measurement
Baseline, Cycle 1 Day-1, Cycle 2 - Day 1, Cycle 3 - Day 1
Pharmacokinetics of LY2624587, area under the concentration-time curve (AUC)
Cycle 1 - Cycle 12
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Study Design & Arms

AllocationNON_RANDOMIZED
MaskingNONE
ModelSINGLE_GROUP
PurposeTREATMENT

Treatment Arms

ArmTypeDescription
LY2624587EXPERIMENTAL -

Interventions

NameTypeDescription
LY2624587DRUG6-900 mg, administered intravenously, weekly for a minimum of one (1) 28 day cycle. If patients are determined to be receiving benefit, study treatment may be continued for up to one (1) year (12 cycles of 28 days).
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Eligibility Criteria

Age Range18 Years to N/A
SexALL
Healthy VolunteersNo
Study Sites2

Inclusion Criteria: * Present with histological or cytological evidence of a diagnosis of cancer (solid tumors, lymphoma, or chronic lymphocytic leukemia) that is advanced and/or metastatic. The patient must be, in the judgement of the investigator, an appropriate candidate for experimental therapy...

Countries:United States
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Competitive Landscape -Cancer 5 trials (matched to "Metastatic Cancer")

Frequently asked questions about LY2624587

What is LY2624587 used for?

LY2624587 is an investigational small molecule being studied for the treatment of metastatic cancer. It is in Phase 1 clinical development and has been evaluated in a completed trial involving patients with advanced cancer. The drug is not yet approved and remains under investigation.

Who makes LY2624587?

LY2624587 is being developed by Eli Lilly and Company, a pharmaceutical company traded on the NYSE under the ticker symbol LLY. The company is conducting clinical research to evaluate the safety and efficacy of this investigational drug in patients with metastatic cancer.

What phase is LY2624587 in?

LY2624587 is in Phase 1 clinical development. It has completed one Phase 1 trial, which was an uncontrolled, non-randomized study. The drug is still investigational and has not been approved for any use.

What clinical trials is LY2624587 in?

LY2624587 has been studied in one clinical trial, identified as NCT01139788, titled "A Study of LY2624587 in Patients With Advanced Cancer." This Phase 1 trial was completed and enrolled 56 participants with metastatic cancer in the United States.

Is LY2624587 FDA approved?

LY2624587 is not FDA approved. It is an investigational drug that has completed a Phase 1 clinical trial. The drug is still in clinical development and has not been authorized for marketing or use in patients outside of clinical research settings.