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Lixte Biotechnology Holdings, Inc.

$7.2

+0.32 (+4.65%)

D 20Pipeline Score Richly Valued Biotech · Clinical
Market Cap
72.81 M
EPS
-1.12
P/E Ratio
-
Value Trade
1.66 M
SEC Financials
Q1 2026
  • Dilution Risk

    80%
  • R&D Expenses

    333.38 K

  • Operating CF

    -1.83 M


  • Total Assets

    10.87 M

  • Total Liabilities

    1.69 M

  • Equity

    7.95 M

  • D/E Ratio

    12,345

8.09 %
Week
65.87 %
1 Month
86.67 %
3 Month
31.84 %
6 Month
-78.92 %
5 Year
-90.3 %
All Time
Cash Data
Distressed
  • Cash Position

    3.25 M

  • Monthly Burn

    610.00 K

  • Runway

    4.4 mo

  • Burn Trend

    Accelerating
  • SEC Filing

    May 14, 2026
Overview
Volume
205.83 K
52 Week Range
0.64 - 6.26
% held by Insiders
12.02 %
% held by Institutions
4.21 %
Enterprise Value
71.85 M
Total Shares
11.62 M
Short %
1.61 %
Float Shares
11.61 M
Company Description
HQ: 433 PLAZA REAL, BOCA RATON, FL...
Employees:3

locked

Upcoming Catalyst
Catalyst Drug/Treatment Stage Probability of Approval Description Drug Type Therapeutic Area Source
LB-100 Ovarian clear cell cancer
Phase 1B/2
Small Molecules
Oncology
LB-100 Ovarian clear cell cancer
Phase 1B/2
Small Molecules
Oncology
LB-100 Ovarian clear cell cancer
Phase 1B/2
Small Molecules
Oncology
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Drug Pipeline Intelligence
D20
Pipeline Score
$0M
Pipeline Value
Richly Valued
Valuation Signal
1
Drugs Scored
0.0x
rNPV / MCap
Top 19%
Micro Cap
(rank 734 of 905)
Percentile Rank
Lixte Biotechnology Holdings, Inc. faces pipeline headwinds (20/100), with $47M risk-adjusted pipeline value, led by LB-100 in Tumors (Phase 1), but cash runway is a concern.
Showing 1 of 1 assets
DrugIndicationPhaseNCT IDPTRSrNPVStatusEnrollmentVelocityDesignCompletionML SignalLast Change
LB-100
Small molecule
Myelodysplastic SyndromesPhase 1NCT0388666222% $47M RECRUITING 47 STALLED F (17) Jul 1, 2021LOW_RISKLOW
May 26, 2026
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Clinical Trial Results
Drug Name Indications Phase Date Trial Results Summary Title Source
Example Drug
Example indication for clinical evaluation
Phase 3
2025-12-01
Example Drug
Example indication for clinical evaluation
Phase 3
2025-12-01
Example Drug
Example indication for clinical evaluation
Phase 3
2025-12-01
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Inside Trades
TREND
CORPORATE INSIDERS BOUGHT SHARES WORTH 1.8M IN THE LAST 3 MONTHS
YEARLY INSIDER TRANSACTIONS
Sector Avg.
INSIDERS
SOLD
INSIDERS
BOUGHT
POSITIVE SENTIMENT Based on 22 Insiders Transactions
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Hedge Funds
TREND
HEDGE FUNDS INCREASED HOLDINGS BY 200.0K SHARES IN THE LAST QUARTER
Shares Held
2040.00B1530.00B1020.00B510.00B0
Q3
2024
Q4
2024
Q1
2025
Q2
2025
HEDGE FUNDS
SOLD
HEDGE FUNDS
BOUGHT
POSITIVE SENTIMENT Based on 27 hedge funds in the last quarter
18 buying (3 new)·9 selling (1 exited)·2 unchanged
Fund Count
60%
Share Volume
25%
Conviction
15%
HedgeFund Name
( 3 )
% of Portfolio Current MV
-
Shares Owned
-
Activity
Avg Price $0

Example Capital Management

2.5 %
15.00 M
250.00 K

Example Capital Management

2.5 %
15.00 M
250.00 K

Example Capital Management

2.5 %
15.00 M
250.00 K
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Biotech Analyst Ratings
Symbol
Firm
Rating
Action
Price Target
Upside
date
LIXT
Example Securities
Buy
Initiated
$150.00
+25%
2026-01-15
LIXT
Example Securities
Buy
Initiated
$150.00
+25%
2026-01-15
LIXT
Example Securities
Buy
Initiated
$150.00
+25%
2026-01-15
Unlock Biotech Analyst Ratings data
LIXT Stock Forecast & Analyst Consensus
BUY
Analyst Ratings
Buy65.0%
Hold25.0%
Sell10.0%
Price Target Trend
Average$24.00
Low$18.00
High$32.00
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LIXT Institutional Ownership Trends
Current Insider %
5.20%
+0.00%
Current Institutional %
62.40%
+0.00%
Total Ownership
67.60%
Insider + Institutional
Data Points
1
1 Ticker(s)
Option Chain Statistics
ExpirationVolumeOpen InterestImplied Volatility CallsImplied Volatility Puts
CallsPutsPut-Call RatioCallsPutsPut-Call RatioIVOiWaIvVWaIvIVOiWaIvVWaIv
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Option Chain
CallsStrikePuts
Last PriceVolumeOpen InterestLast PriceVolumeOpen Interest
No data available
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Open interest
0 600K 1.2M 1.8M Avg OI 1.00 M Open Interest
0 1 2 3 1.1 Put-Call Ratio
Today's Open Interest
1.00 M
Put-Call Ratio
1.1
Put Open Interest
480.00 K
Call Open Interest
520.00 K
Open Interest Avg (30-day)
900,000
Today vs Open Interest Avg (30-day)
11.11%
Option Volume
0 450K 900K 1.4M Avg OV 750.00 K Option Volume
0 1 2 3 0.95 Put-Call Ratio
Today's Volume
750.00 K
Put-Call Ratio
0.95
Put Volume
360.00 K
Call Volume
390.00 K
Volume Avg (30-day)
800,000
Today vs Volume Avg (30-day)
-6.25%
Company News
LIXT
Jun 12, 2026
LIXTGeneral

LIXTE Biotechnology to Acquire NOMAD Transportable Power Systems, the Market Leader in Mobile, Utility-Grade Battery Energy Storage Systems (BESS)

LIXTE Biotechnology Holdings, Inc. has announced its acquisition of NOMAD Transportable Power Systems, a leader in mobile battery energy storage systems. This strategic move aims to address the growing demand for reliable electrical power amid a power availability crisis. Following the acquisition, the company will be renamed NOMAD Power Solutions, focusing on scalable infrastructure for energy solutions.

Read more →
LIXT
May 14, 2026
LIXTGeneral

LIXTE Biotechnology Files First Quarter 2026 Quarterly Report on Form 10-Q; Provides Operational Progress Update

LIXTE Biotechnology has filed its Q1 2026 report, highlighting advancements in its lead compound LB-100, which shows synergy with existing cancer treatments. The company is expanding its ovarian cancer trial following positive safety results. Additionally, the acquisition of Liora Technologies is expected to enhance its capabilities in proton therapy. LIXTE remains focused on innovative cancer therapies and strategic growth.

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LIXT
Apr 13, 2026
LIXTPhases

Favorable Results of Ovarian Cancer Study Presented at Annual Society of Gynecological Care Conference

LIXTE Biotechnology Holdings presented preliminary results from a clinical trial combining LB-100 with Dostarlimab at the Society of Gynecological Cancer Conference. The findings indicate a promising safety profile and efficacy for ovarian cancer patients, with a disease control rate of 40%. An additional cohort is being enrolled to further assess the treatment's potential.

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LIXT
Apr 1, 2026
LIXTGeneral

LIXTE Biotechnology Files 2025 Annual Report on Form 10K, Provides Operational Highlights of Transformative Year

LIXTE Biotechnology Holdings has filed its Annual Report on Form 10-K for 2025, highlighting a transformative year. The company advanced its lead compound LB-100 and completed a strategic acquisition. Additionally, LIXTE raised capital to strengthen its balance sheet, positioning itself for future growth and innovation in cancer treatments.

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LIXT
Feb 18, 2026
LIXTGeneral

LIXTE Biotechnology Appoints Sidney Braun as CEO of its Liora Technologies Europe Ltd. Subsidiary

LIXTE Biotechnology has appointed Sidney Braun as CEO of its subsidiary, Liora Technologies Europe Ltd. Braun brings over 20 years of experience in the healthcare sector and was instrumental in Liora's establishment. His leadership is expected to advance Liora's innovative LiGHT System technology, aimed at improving cancer treatment outcomes.

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LIXT
Jan 21, 2026
LIXTConferences/Events

DE LA SOUL-LED “GOOD HEALTH SUMMIT” LAUNCHES FEBRUARY 19 AT MOREHOUSE COLLEGE

The Good Health: Mind, Body & Soul Summit, sponsored by LIXTE Biotechnology, will be held on February 19 at Morehouse College. This invitation-only event aims to promote health equity for Black men and families, featuring discussions on various health topics. De La Soul's involvement emphasizes the connection between music, culture, and wellness.

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LIXT
Jan 20, 2026
LIXTConferences/Events

LIXTE Biotechnology Attending the DealFlow Discovery Conference, January 28-29

LIXTE Biotechnology Holdings, Inc. will attend the DealFlow Discovery Conference on January 28-29, 2026, in Atlantic City, New Jersey. CEO Geordan Pursglove will hold one-on-one meetings with investors. The company is focused on developing LB-100, a first-in-class cancer therapy, which is currently in clinical trials for various cancer types.

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LIXT
Dec 24, 2025
LIXTPhases

LIXTE and its Collaborators Expand Clear Cell Ovarian Cancer Trial

LIXTE Biotechnology Holdings is expanding its clinical trial for ovarian clear cell cancer by doubling the patient enrollment from 21 to 42. The trial, which combines LIXTE's LB-100 with GSK's Dostarlimab, aims to enhance immunotherapy effectiveness. Initial findings are expected to be presented in the first half of 2026, reflecting the company's commitment to innovative cancer treatments.

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LIXT
Oct 29, 2025
LIXTConferences/Events

LIXTE Biotechnology Holdings to Present at the Spartan Capital Investor Conference 2025, November 3

LIXTE Biotechnology Holdings will present at the Spartan Capital Investor Conference on November 3, 2025. CEO Geordan Pursglove will discuss the company's lead compound, LB-100, a novel cancer therapy. The conference will facilitate one-on-one meetings with investors, highlighting LIXTE's commitment to advancing cancer treatment options.

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LIXT
Oct 16, 2025
LIXTGeneral

LIXTE Biotechnology Holdings Highlights Q4 2025 Priorities, Including Ongoing Advancement of Lead Candidate LB-100, Strategic Oncology Business Development and Acquisition Plans

LIXTE Biotechnology Holdings has outlined its priorities for Q4 2025, focusing on the advancement of its lead candidate LB-100 and strategic acquisitions in oncology. The company is in advanced negotiations for potential acquisitions to enhance its pipeline. LB-100 has shown promise in clinical trials for various cancer types, but the company acknowledges the risks associated with its forward-looking statements.

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LIXT
Sep 3, 2025
LIXTGeneral

LIXTE Biotechnology Holdings Appoints Two New Board Members and New Chief Financial Officer

LIXTE Biotechnology Holdings has appointed Lourdes Felix and Guy Primus to its Board of Directors and named Peter Stazzone as the new Chief Financial Officer. The company has also relocated its corporate headquarters to Boca Raton, aiming to enhance operational efficiency. The new appointments are expected to strengthen LIXTE's focus on developing innovative cancer therapies.

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LIXT
Aug 18, 2025
LIXTGeneral

LIXTE Biotechnology Holdings Provides Corporate Update

LIXTE Biotechnology Holdings has provided a corporate update highlighting significant developments, including the completion of two financings that raised $6.5 million and regaining compliance for Nasdaq listing. The company announced management changes, the formation of a scientific advisory committee, and published new findings in Nature that support its ongoing clinical trials with LB-100. Additionally, LIXTE has launched a new pre-clinical study.

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LIXT
Jul 8, 2025
LIXTGeneral

Lixte Biotechnology Holdings, Inc. Announces the Closing of $1.5 Million Registered Direct Offering

Lixte Biotechnology Holdings, Inc. has successfully closed a registered direct offering, raising approximately $1.5 million through the sale of shares of Common Stock. The offering price was set at $1.54 per share, with proceeds expected to be used for general corporate purposes. The transaction was facilitated by Spartan Capital Securities, LLC.

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LIXT
Jul 2, 2025
LIXTGeneral

Lixte Biotechnology Holdings, Inc. Announces the Closing of $5.0 Million Private Placement Priced at the Market

Lixte Biotechnology Holdings, Inc. has successfully closed a $5.0 million private placement with accredited investors. The offering included shares of Common Stock, Series B Convertible Preferred Stock, and Common Warrants. The funds will be utilized for general corporate purposes and working capital. The transaction closed on July 2, 2025, with Spartan Capital Securities acting as the exclusive placement agent.

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Competitive Position
How LIXT ranks across every disease it competes in
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See how LIXT ranks against every competitor across each disease it develops in: phase, best drug, trials and likelihood of approval.
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