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Lixte Biotechnology Holdings, Inc.

$7.21

-0.46 (-6%)

F 16Pipeline Score Richly Valued Biotech · Clinical
Market Cap
72.81 M
EPS
-1.12
P/E Ratio
-
Value Trade
1.66 M
SEC Financials
Q1 2026
  • Dilution Risk

    80%
  • R&D Expenses

    333.38 K

  • Operating CF

    -1.83 M


  • Total Assets

    10.87 M

  • Total Liabilities

    1.69 M

  • Equity

    7.95 M

  • D/E Ratio

    12,345

8.09 %
Week
65.87 %
1 Month
86.67 %
3 Month
31.84 %
6 Month
-78.92 %
5 Year
-90.3 %
All Time
Cash Data
Distressed
  • Cash Position

    3.25 M

  • Monthly Burn

    610.00 K

  • Runway

    3.4 mo

  • Burn Trend

    Accelerating
  • SEC Filing

    May 14, 2026
Overview
Volume
615.06 K
52 Week Range
0.64 - 6.26
% held by Insiders
16.05 %
% held by Institutions
3.81 %
Enterprise Value
71.85 M
Total Shares
11.62 M
Short %
2.25 %
Float Shares
11.61 M
Company Description
HQ: 433 PLAZA REAL, BOCA RATON, FL...
Employees:3

locked

Upcoming Catalyst
Catalyst Drug/Treatment Stage Probability of Approval Description Drug Type Therapeutic Area Source
LB-100 Lead indication
Phase 2

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Small Molecules
Oncology
LB-100 Lead indication
Phase 2

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Small Molecules
Oncology
LB-100 Lead indication
Phase 2

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Small Molecules
Oncology
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Catalyst Timeline

Dated clinical, regulatory & corporate events for Lixte Biotechnology Holdings, Inc.

178Total events
2Upcoming
23Tier-1 (high impact)
2014 – 2026Coverage

Upcoming catalysts 2

TBD
T1Partnership / License
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TBD
T2Oral Presentation
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LB-100

Event history 2

TBD
AcquisitionCorporate
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TBD
Management ChangeCorporate
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Past FDA Catalysts & PDUFA Decisions
Date Drug Catalyst Stage Outcome Reaction Event Move % Best Trade %
2026-06-30
LB-100
Phase 1b/2 Data readout
Phase 1B/2
2026-06-30
LB-100
Phase 1b/2 Data readout
Phase 1B/2
2026-06-30
LB-100
Phase 1b/2 Data readout
Phase 1B/2
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Drug Pipeline Intelligence
F16
Pipeline Score
$0M
Pipeline Value
Richly Valued
Valuation Signal
1
Drugs Scored
0.0x
rNPV / MCap
Top 13%
Micro Cap
(rank 794 of 912)
Percentile Rank
Lixte Biotechnology Holdings, Inc. has significant pipeline risk (16/100), with $47M risk-adjusted pipeline value, led by LB-100 in Tumors (Phase 1), but cash runway is a concern.
Showing 1 of 1 assets
DrugIndicationPhaseNCT IDPTRSrNPVStatusEnrollmentVelocityDesignCompletionML SignalLast Change
LB-100
Small molecule
Myelodysplastic SyndromesPhase 1NCT038866625% $47M RECRUITING 47 STALLED F (17) Jul 1, 2021LOW_RISKLOW
May 26, 2026
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Clinical Trial Results
Drug Name Indications Phase Date Trial Results Summary Title Source
LB-100
Ovarian Cancer
2026-04-13

OS probability 6 months: 0.84 (95%CI 0.64-0.94); OS probability 12 months: 0.69 (95% CI 0.44-0.84); Disease Control Rate: 40% (8/20, 95% CI 19.1-63.9%)

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Favorable Results of Ovarian Cancer Study Presented at Annual Society of Gynecological Care Conference

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LB-100
Ovarian Cancer
2026-04-13

OS probability 6 months: 0.84 (95%CI 0.64-0.94); OS probability 12 months: 0.69 (95% CI 0.44-0.84); Disease Control Rate: 40% (8/20, 95% CI 19.1-63.9%)

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Favorable Results of Ovarian Cancer Study Presented at Annual Society of Gynecological Care Conference

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LB-100
Ovarian Cancer
2026-04-13

OS probability 6 months: 0.84 (95%CI 0.64-0.94); OS probability 12 months: 0.69 (95% CI 0.44-0.84); Disease Control Rate: 40% (8/20, 95% CI 19.1-63.9%)

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Favorable Results of Ovarian Cancer Study Presented at Annual Society of Gynecological Care Conference

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Inside Trades
TREND
CORPORATE INSIDERS BOUGHT SHARES WORTH 1.8M IN THE LAST 3 MONTHS
YEARLY INSIDER TRANSACTIONS
Sector Avg.
INSIDERS
SOLD
INSIDERS
BOUGHT
POSITIVE SENTIMENT Based on 22 Insiders Transactions
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Hedge Funds
TREND
HEDGE FUNDS INCREASED HOLDINGS BY 200.0K SHARES IN THE LAST QUARTER
Shares Held
2040.00B1530.00B1020.00B510.00B0
Q3
2024
Q4
2024
Q1
2025
Q2
2025
HEDGE FUNDS
SOLD
HEDGE FUNDS
BOUGHT
POSITIVE SENTIMENT Based on 27 hedge funds in the last quarter
18 buying (3 new)·9 selling (1 exited)·2 unchanged
Fund Count
60%
Share Volume
25%
Conviction
15%
HedgeFund Name
( 3 )
% of Portfolio Current MV
-
Shares Owned
-
Activity
Avg Price $0

Example Capital Management

2.5 %
15.00 M
250.00 K

Example Capital Management

2.5 %
15.00 M
250.00 K

Example Capital Management

2.5 %
15.00 M
250.00 K
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LIXT Institutional Ownership Trends
Current Insider %
5.20%
+0.00%
Current Institutional %
62.40%
+0.00%
Total Ownership
67.60%
Insider + Institutional
Data Points
1
1 Ticker(s)
Option Chain Statistics
ExpirationVolumeOpen InterestImplied Volatility CallsImplied Volatility Puts
CallsPutsPut-Call RatioCallsPutsPut-Call RatioIVOiWaIvVWaIvIVOiWaIvVWaIv
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Option Chain
CallsStrikePuts
Last PriceVolumeOpen InterestLast PriceVolumeOpen Interest
No data available
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Open interest
0 600K 1.2M 1.8M Avg OI 1.00 M Open Interest
0 1 2 3 1.1 Put-Call Ratio
Today's Open Interest
1.00 M
Put-Call Ratio
1.1
Put Open Interest
480.00 K
Call Open Interest
520.00 K
Open Interest Avg (30-day)
900,000
Today vs Open Interest Avg (30-day)
11.11%
Option Volume
0 450K 900K 1.4M Avg OV 750.00 K Option Volume
0 1 2 3 0.95 Put-Call Ratio
Today's Volume
750.00 K
Put-Call Ratio
0.95
Put Volume
360.00 K
Call Volume
390.00 K
Volume Avg (30-day)
800,000
Today vs Volume Avg (30-day)
-6.25%
Company News
Competitive Position
How LIXT ranks across every disease it competes in
Competitive Position is a premium feature
See how LIXT ranks against every competitor across each disease it develops in: phase, best drug, trials and likelihood of approval.
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