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LB Pharmaceuticals Inc

$32.95

-0.79 (-2.34%)

D 33Pipeline Score Overvalued Pharma · Clinical
Market Cap
806.39 M
EPS
-1.49
P/E Ratio
-
Value Trade
5.52 M
SEC Financials
Q1 2026
  • Dilution Risk

    5%
  • R&D Expenses

    14.64 M

  • Operating CF

    -23.29 M


  • Total Assets

    393.48 M

  • Total Liabilities

    14.79 M

  • Equity

    378.69 M

  • D/E Ratio

    12,345

-8.82 %
Week
-11.9 %
1 Month
16.44 %
3 Month
75.75 %
6 Month
48 %
5 Year
48 %
All Time
Cash Data
Healthy
  • Cash Position

    365.64 M

  • Monthly Burn

    7.76 M

  • Runway

    45.4 mo

  • Burn Trend

    Accelerating
  • SEC Filing

    May 12, 2026
Overview
Volume
186.56 K
52 Week Range
13.36 - 33.47
% held by Insiders
27.59 %
% held by Institutions
87.22 %
Enterprise Value
444.22 M
Total Shares
28.66 M
Short %
20.73 %
Float Shares
23.84 M
Company Description
HQ: 575 MADISON AVENUE, NEW YORK, ...
Employees:27

locked

Upcoming Catalyst
Catalyst Drug/Treatment Stage Probability of Approval Description Drug Type Therapeutic Area Source
LB-102 acute schizophrenia
Phase 3

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Small Molecules
Psychiatric Disorders
LB-102 acute schizophrenia
Phase 3

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Small Molecules
Psychiatric Disorders
LB-102 acute schizophrenia
Phase 3

Subscribe to access the data.

Small Molecules
Psychiatric Disorders
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Catalyst Timeline

Dated clinical, regulatory & corporate events for LB Pharmaceuticals Inc

32Total events
7Upcoming
5Tier-1 (high impact)
2025 – 2029Coverage

Upcoming catalysts 7

2027
T2Trial Initiation
Expected initiation of Phase 2 trial in adjunctive major depressive disorder
LB-102adjunctive major depressive disorderPhase 2
Q2 2027
T1Topline Readout
Topline data from Phase 3 NOVA-2 trial expected
LB-102schizophreniaPhase 3
Q1 2028
T1Topline Readout
Topline data from Phase 2 ILLUMINATE-1 trial in bipolar depression
LB-102bipolar depressionPhase 2
Q2 2029
T2Runway Guidance Update
Cash runway guidance into Q2 2029
TBD
T2Trial Initiation
LB-102 advancing into Phase 2 clinical trial for bipolar depression
LB-102bipolar depressionPhase 2
TBD
T2Pre NDA Meeting
Pre-NDA meeting with FDA after positive NOVA-2 results
LB-102schizophreniaPhase 3
2029-H1
T1Topline Readout
Topline data from Phase 2 trial in adjunctive MDD
LB-102major depressive disorder (adjunctive)Phase 2

Event history 25

Jun 30, 2026
Management ChangeCorporate
Appointment of Christopher Zergebel as Senior Vice President, Clinical Operations
Jun 16, 2026
Oral PresentationPresentation
H.C. Wainwright 7th Annual Neuro Perspectives Hybrid Conference presentation
Jun 4, 2026
Oral PresentationPresentation
Jefferies Global Healthcare Conference presentation
May 13, 2026
Trial InitiationLB-102Trial
Initiated Phase 2 ILLUMINATE-1 trial of LB-102 in bipolar depression
bipolar depressionsource ↗
May 13, 2026
PublicationLB-102Presentation
Published Phase 2 NOVA-1 results in JAMA Psychiatry
schizophreniasource ↗
May 13, 2026
Equity OfferingCorporate
Completed $100 million private placement
May 13, 2026
Quarterly UpdateCorporate
Reported Q1 2026 financial results
Apr 22, 2026
PublicationLB-102Presentation
Publication of Phase 2 NOVA-1 trial results in JAMA Psychiatry
schizophreniasource ↗
Apr 16, 2026
Oral PresentationPresentation
Presentation at 25th Annual Needham Virtual Healthcare Conference
Mar 27, 2026
Oral PresentationLB-102Presentation
Oral presentation of post hoc analysis of LB-102 effect on cognitive performance at SIRS 2026
schizophreniasource ↗
Mar 27, 2026
Trial InitiationLB-102Trial
Initiation of Phase 2 ILLUMINATE-1 trial of LB-102 for bipolar depression
bipolar depressionsource ↗
Mar 25, 2026
Trial InitiationLB-102Trial
Initiation of Phase 2 ILLUMINATE-1 trial for LB-102 in bipolar depression
bipolar depressionsource ↗
Drug Pipeline Intelligence
D33
Pipeline Score
$128M
Pipeline Value
Overvalued
Valuation Signal
1
Drugs Scored
0.2x
rNPV / MCap
Top 42%
Micro Cap
(rank 529 of 911)
Percentile Rank
LB Pharmaceuticals Inc faces pipeline headwinds (33/100), with $321M risk-adjusted pipeline value, led by LB-102 in Schizophrenia (Phase 3).
Showing 1 of 1 assets
DrugIndicationPhaseNCT IDPTRSrNPVStatusEnrollmentVelocityDesignCompletionML SignalLast Change
LB-102
Small molecule
SchizophreniaPhase 3NCT0458812949% $321M COMPLETED 1,795 - -Nov 15, 2021LOW_RISKMay 4, 2022
Unlock Drug Pipeline Intelligence
Clinical Trial Results
Drug Name Indications Phase Date Trial Results Summary Title Source
LB-102
acute schizophrenia
Phase 2
2026-05-13

statistically significant benefit versus placebo at all doses studied, rapid onset of effect at week 1, sustained benefit through the endpoint of the trial

Read More

LB Pharmaceuticals Reports First Quarter 2026 Financial Results and Provides Corporate Update

Read More
LB-102
acute schizophrenia
Phase 2
2026-05-13

statistically significant benefit versus placebo at all doses studied, rapid onset of effect at week 1, sustained benefit through the endpoint of the trial

Read More

LB Pharmaceuticals Reports First Quarter 2026 Financial Results and Provides Corporate Update

Read More
LB-102
acute schizophrenia
Phase 2
2026-05-13

statistically significant benefit versus placebo at all doses studied, rapid onset of effect at week 1, sustained benefit through the endpoint of the trial

Read More

LB Pharmaceuticals Reports First Quarter 2026 Financial Results and Provides Corporate Update

Read More
Unlock Clinical Trial Results data
Inside Trades
TREND
CORPORATE INSIDERS BOUGHT SHARES WORTH 1.8M IN THE LAST 3 MONTHS
YEARLY INSIDER TRANSACTIONS
Sector Avg.
INSIDERS
SOLD
INSIDERS
BOUGHT
POSITIVE SENTIMENT Based on 22 Insiders Transactions
Unlock Inside Trades data
Hedge Funds
TREND
HEDGE FUNDS INCREASED HOLDINGS BY 200.0K SHARES IN THE LAST QUARTER
Shares Held
2040.00B1530.00B1020.00B510.00B0
Q3
2024
Q4
2024
Q1
2025
Q2
2025
HEDGE FUNDS
SOLD
HEDGE FUNDS
BOUGHT
POSITIVE SENTIMENT Based on 27 hedge funds in the last quarter
18 buying (3 new)·9 selling (1 exited)·2 unchanged
Fund Count
60%
Share Volume
25%
Conviction
15%
HedgeFund Name
( 3 )
% of Portfolio Current MV
-
Shares Owned
-
Activity
Avg Price $0

Example Capital Management

2.5 %
15.00 M
250.00 K

Example Capital Management

2.5 %
15.00 M
250.00 K

Example Capital Management

2.5 %
15.00 M
250.00 K
Unlock Hedge Funds table data
LBRX Institutional Ownership Trends
Current Insider %
5.20%
+0.00%
Current Institutional %
62.40%
+0.00%
Total Ownership
67.60%
Insider + Institutional
Data Points
1
1 Ticker(s)
Option Chain Statistics
ExpirationVolumeOpen InterestImplied Volatility CallsImplied Volatility Puts
CallsPutsPut-Call RatioCallsPutsPut-Call RatioIVOiWaIvVWaIvIVOiWaIvVWaIv
2026-07-170 0.00 0 0 - - - - - -
2026-07-170 0.00 0 0 - - - - - -
2026-07-170 0.00 0 0 - - - - - -
Unlock Option Chain Statistics data
Option Chain
CallsStrikePuts
Last PriceVolumeOpen InterestLast PriceVolumeOpen Interest
No data available
Unlock Option Chain data
Unlock Options Chart data
Open interest
0 600K 1.2M 1.8M Avg OI 1.00 M Open Interest
0 1 2 3 1.1 Put-Call Ratio
Today's Open Interest
1.00 M
Put-Call Ratio
1.1
Put Open Interest
480.00 K
Call Open Interest
520.00 K
Open Interest Avg (30-day)
900,000
Today vs Open Interest Avg (30-day)
11.11%
Option Volume
0 450K 900K 1.4M Avg OV 750.00 K Option Volume
0 1 2 3 0.95 Put-Call Ratio
Today's Volume
750.00 K
Put-Call Ratio
0.95
Put Volume
360.00 K
Call Volume
390.00 K
Volume Avg (30-day)
800,000
Today vs Volume Avg (30-day)
-6.25%
Company News
LBRX
Jun 30, 2026
LBRXGeneral

LB Pharmaceuticals Appoints Christopher Zergebel as Senior Vice President, Clinical Operations

LB Pharmaceuticals has appointed Christopher Zergebel as Senior Vice President of Clinical Operations. With over 25 years of experience, Zergebel will lead efforts in executing multiple clinical trials for LB-102, a candidate aimed at treating schizophrenia and bipolar depression. The company is optimistic about the potential of LB-102 to meet significant patient needs.

Read more →
LBRX
May 29, 2026
LBRXConferences/Events

LB Pharmaceuticals to Participate in Upcoming June 2026 Investor Events

LB Pharmaceuticals Inc. will participate in two upcoming investor conferences in June 2026. The events include the Jefferies Global Healthcare Conference and the H.C. Wainwright 7th Annual Neuro Perspectives Hybrid Conference. The company aims to showcase its late-stage development of therapies for neuropsychiatric diseases, particularly its lead candidate, LB-102.

Read more →
LBRX
May 28, 2026
LBRXConferences/Events

LB Pharmaceuticals to Participate in Upcoming June Investor Events

LB Pharmaceuticals Inc. has announced its participation in two upcoming investor conferences, the Jefferies Global Healthcare Conference on June 4, 2026, and the H.C. Wainwright 7th Annual Neuro Perspectives Hybrid Conference on June 16, 2026. The company is focused on developing innovative therapies for schizophrenia and other neuropsychiatric diseases, with its lead candidate, LB-102, showing promise as a potential first-in-class treatment.

Read more →
LBRX
May 13, 2026
LBRXPhases

LB Pharmaceuticals Reports First Quarter 2026 Financial Results and Provides Corporate Update

LB Pharmaceuticals reported its first quarter 2026 financial results, highlighting the initiation of two late-stage clinical trials for its lead product, LB-102, aimed at treating schizophrenia and bipolar depression. The company also announced a strong cash position expected to fund operations through multiple clinical milestones. Positive data from a prior Phase 2 trial has been published, supporting the drug's potential in neuropsychiatric disorders.

Read more →
LBRX
Apr 22, 2026
LBRXPhases

LB Pharmaceuticals Announces Publication in JAMA Psychiatry of Results from Phase 2 NOVA-1 Trial of LB-102 in Schizophrenia

LB Pharmaceuticals announced the publication of positive results from the Phase 2 NOVA-1 trial of LB-102 in JAMA Psychiatry. The investigational drug demonstrated significant efficacy in treating acute schizophrenia and is advancing to a pivotal Phase 3 trial (NOVA-2). If successful, LB-102 could be the first benzamide approved for schizophrenia in the U.S.

Read more →
LBRX
Apr 10, 2026
LBRXConferences/Events
▼ -7.4%on this news

LB Pharmaceuticals Announces Presentation at 25th Annual Needham Virtual Healthcare Conference

LB Pharmaceuticals Inc. announced that CEO Heather Turner will present at the 25th Annual Needham Virtual Healthcare Conference on April 16, 2026. The company is focused on developing therapies for schizophrenia, bipolar depression, and other neuropsychiatric disorders. Their lead candidate, LB-102, aims to be a first-in-class treatment for these conditions.

Read more →
LBRX
Mar 30, 2026
LBRXPhases

LB Pharmaceuticals Presents New Analysis from the Phase 2 NOVA-1 Trial Highlighting LB-102’s Potential Impact on Cognitive Performance at the 2026 Annual Congress of the Schizophrenia International Research Society (SIRS)

LB Pharmaceuticals presented new data on LB-102 at the SIRS conference, highlighting its potential to improve cognitive performance in schizophrenia patients. The Phase 2 NOVA-1 trial showed that LB-102 significantly enhances cognition independently of its effects on overall schizophrenia symptoms. The company is now evaluating cognitive performance as a secondary endpoint in its upcoming Phase 3 trial.

Read more →
LBRX
Mar 27, 2026
LBRXPhases

LB Pharmaceuticals Presents New Analysis from the Phase 2 NOVA-1 Trial Highlighting LB-102’s Potential Impact on Cognitive Performance at the 2026 Annual Congress of the Schizophrenia International Research Society (SIRS)

LB Pharmaceuticals presented new findings from the Phase 2 NOVA-1 trial of LB-102 at the SIRS Congress, highlighting its potential to improve cognitive performance in schizophrenia patients. The analysis showed that cognitive benefits were primarily a direct effect of LB-102, independent of overall symptom improvement. The company plans to evaluate cognitive performance as a secondary endpoint in its upcoming Phase 3 trial.

Read more →
LBRX
Mar 27, 2026
LBRXPhases

LB Pharmaceuticals Reports Fourth Quarter and Full Year 2025 Financial Results and Provides Corporate Update

LB Pharmaceuticals reported positive results from its Phase 2 trial of LB-102 for schizophrenia and has advanced the drug into late-stage development with a pivotal Phase 3 trial. The company also plans to initiate a Phase 2 trial for major depressive disorder in 2027. With a strong financial position, LB Pharmaceuticals aims to expand its pipeline in neuropsychiatric disorders.

Read more →
LBRX
Mar 25, 2026
LBRXPhases

LB Pharmaceuticals Initiates Pivotal Phase 3 Trial (NOVA-2) for LB-102 in Patients with Schizophrenia

LB Pharmaceuticals has initiated its pivotal Phase 3 trial, NOVA-2, for LB-102, targeting schizophrenia. The trial aims to enroll around 460 patients and evaluate the drug's efficacy and safety, with results expected in the second half of 2027. If successful, LB-102 could become the first benzamide approved for schizophrenia in the U.S., addressing significant unmet needs in treatment.

Read more →
LBRX
Mar 9, 2026
LBRXGeneral

LB Pharmaceuticals Appoints R&D Biotech Executive Robert Lenz, M.D., Ph.D. to Board of Directors

LB Pharmaceuticals has appointed Dr. Robert Lenz to its Board of Directors, enhancing its leadership with his extensive experience in neuroscience R&D. The company is progressing its lead product candidate, LB-102, into late-stage clinical development for various neuropsychiatric disorders. Dr. Lenz expressed enthusiasm about contributing to the company's growth and advancing LB-102's potential therapeutic benefits.

Read more →
LBRX
Mar 5, 2026
LBRXConferences/Events

LB Pharmaceuticals to Participate in Upcoming March 2026 Investor Events

LB Pharmaceuticals Inc. announced its participation in two upcoming investor conferences in March 2026. The company is focused on developing innovative therapies for schizophrenia and other neuropsychiatric disorders. Their lead candidate, LB-102, aims to be the first benzamide antipsychotic approved in the U.S. for these conditions.

Read more →
LBRX
Feb 11, 2026
LBRXGeneral

LB Pharmaceuticals Reports Inducement Grant to New Employee Under Nasdaq Listing Rule 5635(c)(4) - February 10, 2026

LB Pharmaceuticals announced the grant of an equity award to Dr. Minako Pazdera, the new General Counsel, under Nasdaq Listing Rule 5635(c)(4). The award consists of options to purchase 140,000 shares, vesting over four years. The company is also advancing its lead candidate, LB-102, with ongoing Phase 2 trials and plans for a Phase 3 trial for schizophrenia.

Read more →
LBRX
Feb 5, 2026
LBRXGeneral
▲ +12.7%on this news

LB Pharmaceuticals Announces $100.0 Million Private Placement

LB Pharmaceuticals has announced a $100 million private placement to fund its Phase 2 trial for LB-102, aimed at treating major depressive disorder. The company will sell over 3.3 million shares and pre-funded warrants to institutional investors. The placement is set to close on February 6, 2026, pending customary conditions.

Read more →
LBRX
Jan 27, 2026
LBRXPhases

LB Pharmaceuticals Initiates Phase 2 ILLUMINATE-1 Trial in Bipolar Depression, Expanding LB-102 Development Program

LB Pharmaceuticals has initiated a Phase 2 trial for LB-102 in bipolar depression, following positive results in schizophrenia. The trial aims to evaluate the drug's efficacy and safety, with results expected in early 2028. The company believes LB-102 can address significant unmet needs in mood disorders, leveraging its favorable pharmacologic profile.

Read more →
LBRX
Jan 21, 2026
LBRXGeneral

LB Pharmaceuticals Appoints Minako Pazdera, J.D., Ph.D. as General Counsel

LB Pharmaceuticals has appointed Dr. Minako Pazdera as General Counsel, bringing over 25 years of experience in corporate governance and intellectual property. Dr. Pazdera's expertise is expected to enhance the company's strategic initiatives as it advances LB-102, a promising treatment for schizophrenia and bipolar depression, into further clinical trials. The company aims to address unmet needs in neuropsychiatric disorders.

Read more →
LBRX
Jan 13, 2026
LBRXGeneral

LB Pharmaceuticals Reports Inducement Grant to New Employee Under Nasdaq Listing Rule 5635(c)(4)

LB Pharmaceuticals announced equity awards to new executives Ellen Rose and Lindsay Beaupre as part of their inducement to join the company. The awards were granted under Nasdaq Listing Rule 5635(c)(4) and include options to purchase shares at a set price. Additionally, LB-102, their lead product, is advancing into Phase 3 trials for schizophrenia after positive Phase 2 results.

Read more →
LBRX
Dec 11, 2025
LBRXGeneral
▼ -5.3%on this news

LB Pharmaceuticals Reports Inducement Grant to New Employee Under Nasdaq Listing Rule 5635(c)(4) - December 10, 2025

LB Pharmaceuticals announced an inducement equity grant to Kaya Pai Panandiker, its new Chief Commercial Officer, under Nasdaq Listing Rule 5635(c)(4). The grant includes options to purchase 195,000 shares at $21.36, vesting over four years. Additionally, LB-102 is progressing to Phase 3 trials following positive Phase 2 results in schizophrenia treatment.

Read more →
LBRX
Nov 12, 2025
LBRXGeneral
▼ -5.6%on this news

LB Pharmaceuticals Appoints Kaya Pai Panandiker as Chief Commercial Officer

LB Pharmaceuticals has appointed Kaya Pai Panandiker as its new Chief Commercial Officer. With over 20 years of experience in the biopharmaceutical industry, she is expected to leverage her expertise in neuroscience commercialization to advance the company's lead product, LB-102, toward registration and commercialization. LB-102, currently in Phase 2 trials with promising results for schizophrenia and bipolar depression, represents a significant potential advancement in treating neuropsychiatric disorders. However, the company acknowledges the challenges ahead, including securing funding and navigating regulatory pathways.

Read more →
LBRX
Nov 6, 2025
LBRXGeneral

LB Pharmaceuticals Reports 3Q 2025 Financial Results and Recent Corporate Updates

LB Pharmaceuticals reported its financial results for Q3 2025, showing reduced research and administrative costs, contributing to a net loss of $3.6 million, down from $14.2 million in Q3 2024. The CEO highlighted the positive results of a recent Phase 2 trial for LB-102, which is set to advance to a Phase 3 trial for acute schizophrenia. The company has a substantial cash reserve of approximately $314.5 million post-IPO, supporting operations expected to last through Q2 2028. Additionally, LB-102 may expand indications into bipolar depression and other neuropsychiatric disorders.

Read more →
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