Financials
Cash Data
- Monthly Burn
- Burn Trend
- Dilution Risk
- SEC Filing
Key Stats
Upcoming Catalysts
FDA decisions, readouts and PDUFA dates · scored by probability of approval
KTTA Catalyst Timeline
Dated clinical, regulatory and corporate events for Pasithea Therapeutics Corp.
Catalyst Timeline
Dated clinical, regulatory & corporate events for Pasithea Therapeutics Corp.
Upcoming catalysts 2
Event history 50
Past FDA Catalysts and PDUFA Decisions
How KTTA actually traded into and out of each decision
| Date | Drug | Catalyst | Stage | Reaction | Event Move % | Best Trade % |
|---|---|---|---|---|---|---|
| 2026-03-31 | PAS-004 (next-generation macrocyclic MEK inhibitor) | Phase 1/1b interim results | Phase 1/1b |
Drug Pipeline Intelligence
| Drug | Indication | Phase | PTRS | rNPV | Status | Enroll | Velocity | Design | Est. Completion | ML Signal | Last Change |
|---|---|---|---|---|---|---|---|---|---|---|---|
| PAS-004 Small moleculeNCT06961565 | NF1 Mutation | Phase 1 | RECRUITING | 56 | Dec 1, 2027 |
Clinical Trial Results
Readouts, endpoints and source filings for every KTTA program
| Drug Name | Indication | Phase | Date | Trial Results Summary | Title | Source |
|---|---|---|---|---|---|---|
| PAS-004 Fast TrackOrphanRare Pediatric | advanced cancer | Phase 1 | 2026-06-30 | 34 patients have been enrolled and dosed; No dose-limiting toxicities (DLTs), and no discontinuations due to TRAEs; 10 patients on study for >90 days, of which 6 patients >150 days, 4 patients >300 days, and 2 patients >365 days; All TRAEs were Grade 1 or Grade 2; Low cumulative rates of rash (12%) and diarrhea (6%)Read More | Pasithea Therapeutics Announces Positive Interim Phase 1 Advanced Cancer Study Data Demonstrating Long-Term Safety and Tolerability, and Durable Clinical Activity in MEK/BRAF-Pretreated Patients, plus Protocol ExpansionRead More |
Inside Trades
| Insider | Side | Shares | Price | Value | Date |
|---|---|---|---|---|---|
| Coastlands Capital LP10% Owner | Buy | 100,000 3,835,035 held | $0.53 | 06/17/2026 |
Hedge Fund 13F Activity
Hedge Funds invested in KTTA
| Fund | % of Portfolio | Current MV | Shares Owned | Activity |
|---|---|---|---|---|
| Opaleye Management Inc. | 0.1 % | 1.06 M | 2.05 M |
KTTA Institutional Ownership Trends
Options Data
Option Volume
Option Chain Statistics
| Expiry | Call Vol | Put Vol | Vol P/C | Call OI | Put OI | OI P/C | IV Call | IV Call OI-Wtd | IV Call Vol-Wtd | IV Put | IV Put OI-Wtd | IV Put Vol-Wtd |
|---|
Real-Time Option Chain
| Calls | Strike | Puts | ||||
|---|---|---|---|---|---|---|
| Last | Vol | OI | Last | Vol | OI | |
| No data available | ||||||
Calls vs Puts by Expiry
Competitive positioning
How KTTA ranks across every disease it competes in
KTTA News
Pasithea Therapeutics Announces Presentation of Initial PAS-004 Clinical Data from Ongoing Phase 1/1b Clinical Trial in Adult NF1 Patients at the 2026 European Neurofibromatosis Conference
Pasithea Therapeutics announced it will present initial clinical data from its Phase 1/1b trial of PAS-004 at the 2026 European Neurofibromatosis Conference. The presentations include an oral presentation on cutaneous neurofibromas and a poster on plexiform neurofibromas. This marks the company's first public disclosure of clinical data from the trial.
Read more →Pasithea Therapeutics Announces Participation in Two September 2026 Investor Conferences
Pasithea Therapeutics Corp. announced its participation in two investor conferences in September 2026. The company will hold one-on-one meetings at the Cantor Global Healthcare Conference and present at the H.C. Wainwright Global Investment Conference. This engagement highlights Pasithea's ongoing development of PAS-004, a macrocyclic MEK inhibitor for chronic diseases.
Read more →Pasithea Therapeutics Announces Presentation of PAS-004 Data to European Society for Medical Oncology (ESMO) Congress 2026
Pasithea Therapeutics has announced that its Phase 1 dose-escalation study of PAS-004 will be presented at the ESMO Congress 2026. The study focuses on the safety and pharmacokinetics of PAS-004 for patients with MAPK pathway-driven advanced solid tumors. The presentation is scheduled for October 23, 2026, in Madrid, Spain, with further details to be released at that time.
Read more →Pasithea Therapeutics Announces Participation in B. Riley Securities Mind, Muscle & Vision Summit
Pasithea Therapeutics Corp. announced its participation in the B. Riley Securities Mind, Muscle & Vision Summit on July 16, 2026. The summit will focus on various neurological and psychiatric disorders, featuring investor meetings and discussions. Pasithea's management will be available for one-on-one meetings, highlighting their ongoing clinical trials for PAS-004, a macrocyclic MEK inhibitor.
Read more →Pasithea Therapeutics Announces Positive Interim Phase 1 Advanced Cancer Study Data Demonstrating Long-Term Safety and Tolerability, and Durable Clinical Activity in MEK/BRAF-Pretreated Patients, plus Protocol Expansion
Pasithea Therapeutics has reported positive interim data from its Phase 1 trial of PAS-004, a MEK inhibitor for advanced cancer patients. The drug demonstrated a favorable safety profile, with all treatment-related adverse events classified as Grade 1 or 2. Notably, some patients exhibited stable disease for over six months, surpassing typical progression-free survival rates for similar treatments. The company plans to expand dose escalation and assess food effects on drug pharmacokinetics.
Read more →Pasithea Therapeutics Announces Amendments to Clinical Study Protocol for Phase 1/1B NF1 Clinical Trial
Pasithea Therapeutics has amended its Phase 1/1b clinical trial protocol for PAS-004 in NF1 patients. The updates include additional dose levels and an extended treatment period, allowing for more comprehensive data collection. The company has successfully enrolled additional patients and aims to provide interim data in Q4 2026.
Read more →Pasithea Therapeutics Announces Exhibit at Children’s Tumor Foundation 2026 NF Conference
Pasithea Therapeutics will exhibit at the Children's Tumor Foundation 2026 NF Conference in Denver, Colorado, from June 26-30, 2026. The company aims to engage with the NF1 community following recent FDA designations for its lead treatment candidate, PAS-004. CEO Dr. Tiago Reis Marques emphasized the importance of collaboration to enhance outcomes for NF1 patients.
Read more →Pasithea Therapeutics Announces Orphan Drug Designation by FDA of PAS-004 for Treatment of Amyotrophic Lateral Sclerosis (ALS)
Pasithea Therapeutics announced that the FDA has granted Orphan Drug Designation to its drug PAS-004 for treating Amyotrophic Lateral Sclerosis (ALS). This designation is significant due to the limited treatment options available for ALS, a disease with a high unmet medical need. The company is also conducting clinical trials to explore PAS-004's efficacy and safety.
Read more →Pasithea Therapeutics Announces Appointment of Kartik Krishnan, M.D., Ph.D. as Chief Medical Officer
Pasithea Therapeutics has appointed Dr. Kartik Krishnan as Chief Medical Officer, effective May 1, 2026. Dr. Krishnan will lead clinical development for PAS-004, a MEK inhibitor targeting neurofibromatosis type 1. His extensive experience in advancing therapies is expected to enhance the company's efforts in this area.
Read more →Pasithea Therapeutics Announces Grant of Rare Pediatric Disease Designation (RPDD) by FDA to PAS-004 for Treatment of Neurofibromatosis Type 1 (NF1)
Pasithea Therapeutics has received Rare Pediatric Disease Designation from the FDA for PAS-004, a treatment for Neurofibromatosis type 1 (NF1). This designation is significant as NF1 affects approximately 115,000 individuals in the U.S. The company is also conducting Phase 1/1b trials for PAS-004 in patients with NF1-associated plexiform neurofibromas.
Read more →Pasithea Therapeutics Announces Grant of Fast Track Designation by FDA to PAS-004 for Treatment of Neurofibromatosis Type 1 (NF1) Associated Plexiform Neurofibromas (PN) Causing Significant Morbidity
Pasithea Therapeutics Corp. has received Fast Track designation from the FDA for its drug PAS-004, aimed at treating neurofibromatosis type 1 (NF1) associated plexiform neurofibromas. This designation allows for early and frequent communications with the FDA, facilitating product development. The company is currently engaged in Phase 1/1b clinical trials for this treatment, which addresses the serious health risks posed by plexiform neurofibromas in NF1 patients. The Fast Track status may allow for quicker regulatory approval processes if relevant criteria are met.
Read more →Pasithea Therapeutics to Present at the Oppenheimer 36th Annual Healthcare Life Sciences Conference
Pasithea Therapeutics Corp. will present at the Oppenheimer 36th Annual Healthcare Life Sciences Conference on February 26, 2026. CEO Tiago Reis Marques will discuss the company's lead drug candidate, PAS-004, which is currently in clinical trials for treating NF1-associated plexiform neurofibromas. The presentation will be available via webcast, and management will hold one-on-one meetings with investors.
Read more →Pasithea Therapeutics Provides Outlook on PAS-004 Clinical Programs and Data Release Timelines
Pasithea Therapeutics has provided an update on its PAS-004 clinical programs, highlighting positive early results from its Phase 1 trial in advanced cancer patients and ongoing trials for neurofibromatosis type 1. The company raised $60 million to support these initiatives, aiming to address significant unmet medical needs. However, they acknowledge the inherent risks in clinical trial outcomes and regulatory approvals.
Read more →Pasithea Therapeutics Announces Closing of $60 Million Public Offering of Common Stock
Pasithea Therapeutics has successfully closed a public offering of 80 million shares, raising approximately $60 million. The offering was led by notable healthcare investors and aims to support the company's ongoing clinical trials and research initiatives. The funds will enhance the company's cash runway, expected to last until at least mid-2028.
Read more →Pasithea Therapeutics Announces Pricing of $60 Million Public Offering of Common Stock
Pasithea Therapeutics Corp. has announced the pricing of a public offering of 80 million shares at $0.75 each, aiming to raise approximately $60 million. The offering is set to close around December 1, 2025, and will support the company's ongoing research and development efforts, particularly for its lead drug candidate, PAS-004. The offering is facilitated by H.C. Wainwright & Co. and is backed by several healthcare-focused investors.
Read more →Pasithea Therapeutics Announces $1 Million Award by ALS Association to Study the Efficacy, Safety, and Tolerability of PAS-004 for Treatment of ALS
Pasithea Therapeutics Corp. has announced that it has been awarded a $1 million grant from the ALS Association to conduct a clinical trial for its drug PAS-004 in amyotrophic lateral sclerosis (ALS) patients. The trial will assess the safety, tolerability, and efficacy of PAS-004, a next-generation macrocyclic MEK inhibitor, which has previously shown promising results in animal models. This funding will facilitate the initiation of the first human clinical trial for PAS-004 aimed specifically at ALS, marking a significant milestone for the company.
Read more →Pasithea Therapeutics Announces Completion of Cohort 7 in Ongoing Phase 1 Trial of PAS-004 in Advanced Cancer Patients, with Positive Safety, Pharmacokinetic (PK), and Pharmacodynamic (PD) Data
Pasithea Therapeutics has completed Cohort 7 of its Phase 1 trial for PAS-004, a MEK inhibitor for advanced cancer patients. The trial reported no treatment-related adverse events and demonstrated a favorable pharmacokinetic profile. The safety review committee has recommended escalating to Cohort 8, indicating positive momentum for the drug's development.
Read more →Pasithea Therapeutics Announces Positive PAS-004 Tablet Pharmacokinetic (PK) Data in Ongoing Phase 1/1b Trial in Adult NF1 Patients
Pasithea Therapeutics announced positive pharmacokinetic data for its PAS-004 tablet formulation in an ongoing Phase 1/1b trial for adult patients with neurofibromatosis type 1. The tablet showed approximately threefold higher exposure compared to the capsule formulation, allowing for lower dosing with improved predictability. The trial continues to evaluate the safety and efficacy of PAS-004.
Read more →Pasithea Therapeutics Announces Positive Phase 1 Data Including Partial Response, Demonstrating Monotherapy Clinical Activity and Favorable Safety Profile for PAS-004 in Advanced Cancer
Pasithea Therapeutics has announced positive interim Phase 1 data for its oral MEK inhibitor, PAS-004, used in advanced cancer patients. The trial demonstrated partial response and stable disease in patients with BRAF V600E mutations, achieving a 71.4% disease control rate. Additionally, PAS-004 exhibited a favorable safety profile with mostly mild treatment-related adverse effects. These encouraging results suggest potential for PAS-004 as a leading treatment option for neurofibromatosis type 1-related tumors.
Read more →Pasithea Therapeutics Announces Activation of Clinical Trial Site at University of Alabama at Birmingham for Ongoing Phase 1/1b Trial of PAS-004 in Adult NF1 Patients
Pasithea Therapeutics has activated a new clinical trial site at the University of Alabama at Birmingham for its Phase 1/1b study of PAS-004 in adult patients with neurofibromatosis type 1. The trial aims to evaluate the safety and efficacy of PAS-004 in treating symptomatic plexiform neurofibromas. Enrollment at the UAB site is expected to begin immediately, enhancing the company's commitment to advancing care for NF1 patients.
Read more →