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Kodiak Sciences Inc

KODFDA catalysts, PDUFA dates & pipeline intelligence
$81.09
▼ -10.3 · -11.24%

Financials

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52W LOW $12.6452W HIGH $104.00
Volume
2.41 M
Value Traded
23.48 M
Short % Float
16.31%
-13.97%Week
+145.8%1 Month
+96.58%3 Month
+100.67%6 Month
-55.74%5 Year
+262.3%All Time

Cash Data

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Key Stats

Market Cap
5.10 B
EPS (TTM)
-3.85
P/E Ratio
-
Ent. Value
4.97 B
Total Shares
62.85 M
Float Shares
57.48 M
Insiders
8.55%
Institutions
102.94%

Upcoming Catalysts

FDA decisions, readouts and PDUFA dates · scored by probability of approval

Catalyst Drug / Treatment Stage Prob. of Approval Description Drug Type Therapeutic Area Source
Phase 3 topline data readout
KSI-101
macular edema secondary to inflammation (MESI)
Phase 3BiologicsOphthalmologic System
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Every FDA decision, readout and PDUFA date, with drug type, therapeutic area and a PoA score you can trade on.
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PoA blends historical approval base rates, trial design score and FDA review track record.

KOD Catalyst Timeline

Dated clinical, regulatory and corporate events for Kodiak Sciences Inc

Catalyst Timeline

Dated clinical, regulatory & corporate events for Kodiak Sciences Inc

440Total events
12Upcoming
73Tier-1 (high impact)
2018 to 2027Coverage

Upcoming catalysts 2

T1Topline Readout
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KSI-101
T2Enrollment Complete
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KSI-101

Event history 50

◆Oral PresentationZenkudaPresentation
Phase 3 GLOW2 data for Zenkuda in diabetic retinopathy presented at AAO 2026
diabetic retinopathysource ↗
◆Oral PresentationZenkudaPresentation
First scientific presentation of Phase 3 DAYBREAK results for Zenkuda and tabirafusp-ted at AAO 2026 Retina Subspecialty Day
wet age-related macular degenerationsource ↗
◆Oral PresentationKSI-101Presentation
Phase 1b APEX data for KSI-101 in MESI presented at AAO 2026 Uveitis Subspecialty Day
macular edema secondary to inflammation (MESI)source ↗
◆Oral Presentationtabirafusp-tedPresentation
First scientific presentation of Phase 3 DAYBREAK results for Zenkuda and tabirafusp-ted at AAO 2026 Retina Subspecialty Day
wet age-related macular degenerationsource ↗
▲Topline ReadoutZenkudaClinical Data
Kodiak announced topline results from Phase 3 DAYBREAK in wet AMD
wet age-related macular degenerationsource ↗
◆Topline ReadoutKSI-501Clinical Data
Topline results from DAYBREAK Phase 3 study of Zenkuda and KSI-501 in wet AMD
wet age-related macular degenerationsource ↗
●R&D DayPresentation
Kodiak to present detailed DAYBREAK results at company webcast
▲Primary Endpoint Mettabirafusp-tedClinical Data
DAYBREAK met primary endpoint for tabirafusp-ted with non-inferior vision gains vs aflibercept at Year 1
wet age-related macular degenerationsource ↗
▲Primary Endpoint MetZenkudaClinical Data
DAYBREAK met primary endpoint for Zenkuda with non-inferior vision gains vs aflibercept at Year 1
wet age-related macular degenerationsource ↗
▲Topline Readouttabirafusp-tedClinical Data
Kodiak announced topline results from Phase 3 DAYBREAK in wet AMD
wet age-related macular degenerationsource ↗
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Past FDA Catalysts and PDUFA Decisions

How KOD actually traded into and out of each decision

Date Drug Catalyst Stage Reaction Event Move % Best Trade %
2026-10-10Zenkuda (tarcocimab tedromer) Phase 3 data presentation Phase 3
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Reaction: 30 trading days around the event · Event Move: close to close on decision day · Best Trade: peak run-up from entry 10 days before the decision

Drug Pipeline Intelligence

Pipeline Score
Pipeline Value
Valuation Signal
3
Drugs Scored
rNPV / MCap
Top Drug
Top 23%
Small Cap
(rank 152 of 656)
Percentile Rank
Showing 6 of 6 assets
DrugIndicationPhasePTRSrNPVStatusEnrollVelocityDesignEst. CompletionML SignalLast Change
Tarcocimab tedromer Monoclonal antibodyNCT06556368Wet Age-related Macular DegenerationPhase 3 ACTIVE NOT_RECRUITING 675Aug 1, 2027
KSI-101 Small moleculeNCT06990399Macular Edema Secondary to InflammationPhase 3 RECRUITING 900Nov 1, 2027
Tabirafusp tedromer Small moleculeNCT07734844Diabetic Macular Edema (DME)Phase 3 RECRUITING 910Sep 1, 2029
Tarcocimab Monoclonal antibodyCompletedNCT06270836Diabetic RetinopathyPhase 3 COMPLETED 255Feb 13, 2026
KSI-301 Small moleculeCompletedNCT04592419Macular EdemaPhase 3 COMPLETED 568Jan 19, 2023
KSI-301 Small moleculeCompletedNCT04964089Wet Age-related Macular DegenerationPhase 3 COMPLETED 557Apr 6, 2023
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Clinical Trial Results

Readouts, endpoints and source filings for every KOD program

Drug Name Indication Phase Date Trial Results SummaryTitleSource
Zenkuda, tabirafusp-ted wet age-related macular degenerationPhase 32026-10-07the study met its primary endpoint for each investigational treatment, with both Zenkuda and tabirafusp-ted demonstrating non-inferior vision gains compared with aflibercept at Year 1Read MoreKodiak Sciences to Present Clinical Data Across All Three Late-Stage Programs at AAO 2026Read More
Scroll for more · summaries link to the source press release
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Inside Trades

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Monthly insider buys and sells against the stock price, with the insider sentiment reading.
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InsiderSideSharesPriceValueDate
BAKER BROS. ADVISORS LPDirector, 10% OwnerBuy 619 1,668,448 held$84.24 09/29/2026
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Hedge Fund 13F Activity

Fund % of Portfolio Current MV Shares Owned Activity
BAKER BROS. ADVISORS 3.9 % (-11.4 %) 776.05 M 19.92 M
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Shares held by hedge funds each quarter, and who bought or sold.

KOD Institutional Ownership Trends

Options Data

Option Volume

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Option Chain Statistics

ExpiryCall VolPut VolVol P/CCall OIPut OIOI P/CIV CallIV Call OI-WtdIV Call Vol-WtdIV PutIV Put OI-WtdIV Put Vol-Wtd
2026-10-16
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Real-Time Option Chain

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LastVolOILastVolOI
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Calls vs Puts by Expiry

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Competitive positioning

How KOD ranks across every disease it competes in

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See how KOD ranks against every competitor across each disease it develops in: phase, best drug, trials and likelihood of approval.
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KOD News

KOD
Oct 7, 2026
KODConferences/Events

Kodiak Sciences to Present Clinical Data Across All Three Late-Stage Programs at AAO 2026

Kodiak Sciences Inc. announced that it will present clinical data for its late-stage programs at the AAO 2026. Key presentations include the Phase 3 DAYBREAK results for Zenkuda and tabirafusp-ted in wet AMD, as well as data from the GLOW2 and APEX studies. The DAYBREAK study met its primary endpoint, showing promising results compared to aflibercept.

Read more →
KOD
Sep 28, 2026
KODPhases
▲ +178%on this news· ran to +204% by day 3

Zenkuda and tabirafusp-ted Meet Primary Endpoints in Pivotal DAYBREAK Trial in wAMD, with Zenkuda Demonstrating a Potential New Standard-of-Care Profile with Strong Immediacy and Sustained Clinical Effect with Majority of Patients on 24-week Dosing Interval Using Strict Treat-to-Dryness Real World Retreatment Criteria.

Zenkuda (tarcocimab tedromer) successfully met its primary endpoint in the pivotal DAYBREAK trial for wet age-related macular degeneration (wAMD), showing significant vision improvements and rapid retinal drying. Notably, 54% of patients were able to maintain a 6-month dosing interval. This positions Zenkuda as a potential first-line treatment option.

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KOD
Sep 25, 2026
KODPhases
▲ +178%on this news· ran to +204% by day 3shared move

Kodiak Sciences to Present Topline Results on September 28, 2026 from DAYBREAK Pivotal Phase 3 Study of Zenkuda and KSI-501 in Patients with Wet Age-Related Macular Degeneration

Kodiak Sciences Inc. will present topline results from its DAYBREAK Phase 3 study on September 28, 2026. The study evaluates Zenkuda and KSI-501 for treating wet age-related macular degeneration. The webcast will provide insights into the efficacy of these treatments, which target a significant market in retinal diseases.

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KOD
Aug 13, 2026
KODPhases

Kodiak Sciences Announces Recent Business Highlights and Second Quarter 2026 Financial Results

Kodiak Sciences reported its second quarter 2026 financial results, highlighting significant progress in its late-stage clinical portfolio. The company anticipates topline data from three Phase 3 studies by the end of the year, including DAYBREAK and PEAK studies. Despite a net loss of $65.6 million, Kodiak's cash reserves are expected to sustain operations into 2027.

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KOD
Aug 10, 2026
KODPhases

Kodiak Sciences Announces First Patients Enrolled in Global Phase 3 ALTO trial of KSI-501 in Patients with Diabetic Macular Edema

Kodiak Sciences has enrolled the first patients in the global Phase 3 ALTO trial for KSI-501, aimed at treating diabetic macular edema (DME). This trial will compare the efficacy of KSI-501, a bispecific therapy targeting IL-6 and VEGF, against aflibercept. The study seeks to demonstrate improved disease control and visual outcomes for patients with DME, addressing limitations of existing treatments.

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KOD
Aug 6, 2026
KODPhases

Kodiak Sciences Completes Enrollment in First Pivotal Cohort in the Phase 3 PEAK Trial of KSI-101 for Macular Edema Secondary to Inflammation and Reaffirms Topline Clinical Data Release Remains on Track for December 2026

Kodiak Sciences has completed enrollment of 300 patients in the first pivotal cohort of its Phase 3 PEAK trial for KSI-101, targeting macular edema secondary to inflammation. The company anticipates releasing topline data in December 2026. KSI-101 aims to provide a safer and more effective treatment option for patients at risk of vision loss due to MESI.

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KOD
May 28, 2026
KODConferences/Events

Kodiak Sciences to Present at 2026 Jefferies Global Healthcare Conference

Kodiak Sciences Inc. will present at the 2026 Jefferies Global Healthcare Conference on June 4, 2026. CEO Victor Perlroth, M.D., will lead the presentation, showcasing the company's commitment to developing transformative retinal therapeutics. A live webcast will be available for those unable to attend in person.

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KOD
May 7, 2026
KODPhases

Kodiak Sciences Announces Recent Business Highlights and First Quarter 2026 Financial Results

Kodiak Sciences reported positive Phase 3 results for Zenkuda, demonstrating significant efficacy in diabetic retinopathy. The company is advancing its late-stage pipeline with multiple readouts expected in 2026, including studies for wet AMD and macular edema. Despite a net loss of $58.2 million in Q1 2026, Kodiak's cash position supports operations into 2027.

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KOD
May 1, 2026
KODConferences/Events

Kodiak Sciences to Present Pipeline Advances and KSI-101 Clinical Data, Including Results from a MESI Cohort in a Tertiary Care Uveitis Practice, at Upcoming Scientific Conferences

Kodiak Sciences announced it will present clinical data for KSI-101 at the upcoming American Uveitis Society and ARVO meetings. The results from a tertiary care cohort are consistent with previous studies, indicating the drug's potential across diverse patient populations. The company is advancing its pipeline, including KSI-101, KSI-102, and KSI-103, aimed at treating retinal diseases.

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KOD
Apr 1, 2026
KODFDA Updates
▲ +12.3%on this news

Kodiak Sciences Announces Recent Business Highlights and Fourth Quarter and Full Year 2025 Financial Results

Kodiak Sciences reported positive Phase 3 topline results for Zenkuda in diabetic retinopathy and highlighted advancements in its pipeline programs. The company completed enrollment in the Phase 3 DAYBREAK study for wet AMD and continues to develop KSI-101 and other candidates. Despite a net loss increase, Kodiak's cash position supports its operations into 2027.

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KOD
Mar 26, 2026
KODPhases
▲ +74.8%on this newsshared move

Kodiak Sciences Announces Positive Topline Results in GLOW2, the Second Phase 3 Study in Diabetic Retinopathy, Demonstrating Superiority of Zenkuda™ (tarcocimab tedromer) Over Sham

Kodiak Sciences announced positive topline results from the GLOW2 Phase 3 study, showing Zenkuda's superiority over sham in treating diabetic retinopathy. The study included a broader patient population and demonstrated a significant improvement in DRSS scores. Zenkuda was well-tolerated, with no serious ocular adverse events reported, supporting its potential as a long-lasting treatment option.

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KOD
Feb 4, 2026
KODPhases
▼ -6.9%on this news

Final APEX Phase 1b Clinical Results for Kodiak's KSI-101 in Macular Edema Secondary to Inflammation to be Presented at Angiogenesis 2026

Kodiak Sciences announced the presentation of final results from the Phase 1b APEX study for KSI-101 at the Angiogenesis 2026 meeting. The data indicate significant visual and anatomical improvements in patients with macular edema secondary to inflammation. These findings bolster confidence in KSI-101's potential as a leading therapy for MESI, with ongoing Phase 3 studies actively enrolling participants.

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KOD
Jan 7, 2026
KODConferences/Events
▲ +8.1%on this news

Kodiak Sciences to Present at 44th Annual J.P. Morgan Healthcare Conference Kodiak Sciences Inc. (Nasdaq: KOD), a precommercial retina focused biotechnology company committed to researching, developing and commercializing...

Kodiak Sciences Inc. has announced that its senior management will present at the 44th Annual J.P. Morgan Healthcare Conference on January 12, 2026. The presentation will highlight the company's precommercial efforts and its portfolio of late-stage clinical programs targeting retinal diseases. Kodiak is aiming to address leading causes of blindness with its innovative therapeutics, including candidates in Phase 3 studies. Live webcasting of the event will be available on Kodiak's website.

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KOD
Dec 18, 2025
KODGeneral

Kodiak Sciences Announces Closing of $184 Million Public Offering of Common Stock including Full Exercise of Underwriters' Option to Purchase Additional Shares Kodiak Sciences Inc. (Nasdaq: KOD), a precommercial retina focused biotechnology company committed to researching, developing and commercializing...

Kodiak Sciences Inc. has successfully closed a public offering of 8 million common shares, raising approximately $184 million. This amount includes shares sold through the underwriters' full exercise of their additional purchase option. The funds will strengthen Kodiak's financial position as the company progresses through critical Phase 3 topline readouts for its late-stage clinical assets. The offering was conducted through a previously filed registration statement with the SEC.

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KOD
Dec 16, 2025
KODGeneral

Kodiak Sciences Announces Pricing of Upsized Public Offering of Common Stock Kodiak Sciences Inc. (Nasdaq: KOD), a precommercial retina focused biotechnology company committed to researching, developing and commercializing...

Kodiak Sciences, a biotechnology company focused on retina therapies, has announced the pricing of an upsized public offering of approximately 6.96 million shares at $23.00 per share. This offering is anticipated to raise around $160 million before expenses. The transaction is subject to customary closing conditions and is expected to close on or about December 18, 2025. Additionally, Kodiak has granted underwriters a 30-day option to purchase additional shares.

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KOD
Dec 15, 2025
KODGeneral

Kodiak Sciences Announces Proposed Public Offering of Common Stock

Kodiak Sciences Inc. has announced a proposed public offering of 6 million shares of common stock, with an option for underwriters to purchase an additional 900,000 shares. The offering is subject to market conditions and is intended to support the company's development of transformative retinal therapeutics. The shares will be sold under a previously filed shelf registration statement.

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KOD
Nov 13, 2025
KODGeneral

Kodiak Sciences Announces Recent Business Highlights and Third Quarter 2025 Financial Results

Kodiak Sciences reported strong business highlights and financial results for Q3 2025, showcasing positive momentum in its late-stage programs. The company anticipates continued progress into 2026 with multiple Phase 3 data readouts and a planned BLA filing. Despite a net loss increase and rising R&D expenses, the firm remains optimistic about its pipeline advancements.

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KOD
Nov 12, 2025
KODConferences/Events
▼ -6.8%on this newsshared move

Kodiak Sciences to Present at Upcoming Investor Conferences

Kodiak Sciences Inc. will present at upcoming investor conferences, highlighting its commitment to developing innovative retinal therapeutics. CEO Victor Perlroth will lead the presentations, which will be available via live webcast. The company is advancing three late-stage clinical programs targeting retinal vascular diseases and macular edema.

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KOD
Nov 5, 2025
KODPhases

Follow-up data for Kodiak's KSI-101 from the APEX study showed continued strengthening of clinical effect (≥90% of patients achieving absence of intraretinal and subretinal fluid) through week 20 in macular edema secondary to inflammation (MESI)

Kodiak Sciences has reported promising follow-up data from the APEX study of KSI-101, an investigational therapy for macular edema secondary to inflammation (MESI). The data indicates that over 90% of patients achieved absence of retinal fluid by week 20, with significant improvements in visual acuity. The company aims to advance KSI-101 into Phase 3 studies, potentially establishing it as a cornerstone therapy for MESI.

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About Kodiak Sciences Inc

Palo Alto, CA 124 employees kodiak.com
Headquarters1250 PAGE MILL RD, PALO ALTO, CA, 94304
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