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auto-titrating continuous positive airway pressure

Phase 2

Transient Ischemic Attack | Unknown | Neurology |Johnson & Johnson|Last Updated: Mar 3, 2009

Success Probability

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Market & Valuation

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Trial Design

RandomizedUNCONTROLLED
Total Trials1
Total Enrollment62

FDA Designations

No designations recorded

Clinical trial landscape

auto-titrating continuous positive airway pressure · 1 trial · 2 indications

Phase 2 1
NCT00251290Diagnosis and Treatment of Sleep-Disordered Breathing in the Homes of Patients With Transient Ischemic AttackTransient Ischemic Attack
COMPLETED62 Analytics
PHASE2COMPLETED
Diagnosis and Treatment of Sleep-Disordered Breathing in the Homes of Patients With Transient Ischemic Attack
Transient Ischemic AttackUnlock trial analytics

Study Endpoints

Primary Endpoints

prevalence of sleep-disordered breathing in patients with TIA, proportion of patients who use auto-CPAP >4 hours per night, and change in systolic blood pressure
90 days

Secondary Endpoints

Recurrent vascular events (transient ischemic attack, stroke, myocardial infarction, congestive heart failure requiring hospitalization, and death), sleepiness, cognition, depression, functional status, and quality of life.
90 days
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Study Design & Arms

AllocationRANDOMIZED
MaskingNONE
ModelPARALLEL
PurposeTREATMENT

Interventions

NameTypeDescription
auto-titrating continuous positive airway pressurePROCEDUREContinuous positive Airway pressure (CPAP) use for 90 days post TIA
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Eligibility Criteria

Age Range45 Years to N/A
SexALL
Healthy VolunteersNo
Study Sites3

Inclusion Criteria: transient ischemic attack - Exclusion Criteria:age \<45 years; respiratory distress or known sleep-disordered breathing; chronic obstructive pulmonary disease (COPD) requiring oxygen; pregnancy; time from symptom onset to beginning of study intervention 72 hours; life expectancy ...

Countries:United States
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Frequently asked questions about auto-titrating continuous positive airway pressure

What is auto-titrating continuous positive airway pressure used for in Transient Ischemic Attack?

Auto-titrating continuous positive airway pressure is being studied for use in patients with Transient Ischemic Attack and sleep apnea. It is an investigational therapy in Phase 2 clinical development, intended to address sleep-disordered breathing in this patient population.

Who makes auto-titrating continuous positive airway pressure?

Johnson & Johnson (NYSE: JNJ) is developing auto-titrating continuous positive airway pressure. The therapy is currently in Phase 2 clinical development for Transient Ischemic Attack.

What phase is auto-titrating continuous positive airway pressure in?

Auto-titrating continuous positive airway pressure is in Phase 2 clinical development. It is an investigational therapy and has not been approved by the FDA. One Phase 2 trial has been completed.

What clinical trials is auto-titrating continuous positive airway pressure in?

Auto-titrating continuous positive airway pressure has one completed clinical trial, NCT00251290, titled 'Diagnosis and Treatment of Sleep-Disordered Breathing in the Homes of Patients With Transient Ischemic Attack.' This Phase 2 study enrolled 62 patients in the United States.

Is auto-titrating continuous positive airway pressure FDA approved?

Auto-titrating continuous positive airway pressure is not FDA approved. It is an investigational therapy currently in Phase 2 clinical development for Transient Ischemic Attack, with one completed clinical trial.