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Topiramate; flunarizine · 1 trial · 2 indications
| Name | Type | Description |
|---|---|---|
| Topiramate; flunarizine | DRUG | - |
Inclusion Criteria: * Subjects in Group 1 must be diagnosed with migraine for at least 1 year prior to study start. Subjects must also have received any dose of flunarizine for the prophylaxis of migraine, for a minimum of 4 weeks prior to the run-in phase. Subjects in Group 2 must be healthy subje...
Top 5 of 8 competitors
| Company | Ticker | Trials | Lead Phase | Drugs |
|---|---|---|---|---|
| AbbVie, Inc. | ABBV | 13 | PHASE3 | Atogepant, Ubrogepant, MEDI0618 |
| Pfizer Inc. | PFE | 11 | PHASE3 | Rimegepant, Zavegepant |
| Eli Lilly and Company | LLY | 2 | PHASE3 | Galcanezumab |
| Amgen Inc. | AMGN | 2 | PHASE3 | Erenumab |
| Evommune, Inc. | EVMN | 1 | PHASE2 | EVO756 |
Topiramate; flunarizine refers to a combination of two small molecule drugs studied together for migraine. Johnson & Johnson (ticker JNJ) ran a Phase 1 drug interaction study of topiramate and flunarizine given together or separately. The combination is investigational and is not an approved product.
Topiramate; flunarizine was studied for migraine in a Phase 1 pharmacokinetic drug interaction trial. The trial enrolled 75 participants, including healthy volunteers and people with migraine, to evaluate how the two drugs affect each other when given together or separately. It is not an approved migraine treatment.
Johnson & Johnson, which trades under the ticker JNJ, is the developer associated with the topiramate; flunarizine combination. The company sponsored the Phase 1 drug interaction study of the two agents in migraine.
Topiramate; flunarizine is in Phase 1 development. One Phase 1 trial has been completed, and no active trials are ongoing. The combination is investigational and has not been approved for any indication.
Topiramate; flunarizine has been evaluated in one completed Phase 1 trial, NCT00752466, titled A Drug Interaction Study of the Pharmacokinetics of Topiramate and FLUNARIZINE When Given Together or Separately. The trial enrolled 75 participants aged 18 years and older, including healthy volunteers, and used a randomized, uncontrolled design.