Approval Probability 71%
TA Base Rate26%
Adjusted LOA41%
ML RiskLOW_RISK
| NCT ID | Title | Phase | Status | Enrollment | Velocity | Design | Start | Completion | Last Updated | Sites | Countries |
|---|---|---|---|---|---|---|---|---|---|---|---|
| NCT00840242 | Smoking Reduction or Cessation With Nicotine Replacement Therapy | PHASE3 | COMPLETED | 314 | — | — | Feb 1, 1999 | May 1, 2000 | Apr 25, 2012 | 2 | Czechia |
| Arm | Type | Description |
|---|---|---|
| Nicotine gum | EXPERIMENTAL | Nicotine gum |
| Placebo gum | PLACEBO_COMPARATOR | Placebo gum |
| Nicotine inhaler | ACTIVE_COMPARATOR | Nicotine inhaler |
| Placebo inhaler | PLACEBO_COMPARATOR | Placebo inhaler |
| Name | Type | Description |
|---|---|---|
| Nicotine gum | DRUG | 8-12 pieces per day, maximum 24 daily |
| Placebo gum | DRUG | 8-12 pieces per day, maximum 24 daily |
| Nicotine inhaler | DRUG | 6-12 cartridges per day, maximum 12 daily |
| Placebo inhaler | DRUG | 6-12 cartridges per day, maximum 12 daily |
Inclusion Criteria: * Age above 18 * Smoking \>/= 15 cigarettes/day * Having smoked for 3 years or more * CO \>/= 10ppm at inclusion * Want to reduce smoking * Prepared to adhere to the protocol * Willing to provide signed informed consent * Having made at least one serious attempt to quit smoking ...