JANX May 7, 2026JANXGeneral
Janux Therapeutics Reports First Quarter 2026 Financial Results and Business Highlights
Janux Therapeutics has reported its financial results for the first quarter of 2026. The report includes various business highlights, although specific details about financial performance or strategic initiatives are not provided in the article. The overall tone remains neutral without significant positive or negative developments.
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JANX Apr 28, 2026JANXPhases
Janux Therapeutics Announces Discontinuation of JANX008 Clinical Development
Janux Therapeutics has announced the discontinuation of its JANX008 clinical development after evaluating the Phase 1a study results. Despite some durable responses in select patients, the overall activity was not sufficient to justify further investment. The company will redirect resources to other pipeline opportunities while continuing to develop its broader TRACTr platform.
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JANX Apr 17, 2026JANXPhases
Janux Therapeutics Announces First Participant Dosed in Phase 1 Study of JANX014
Janux Therapeutics has initiated a Phase 1 clinical trial for JANX014, a T cell engager targeting metastatic castration-resistant prostate cancer (mCRPC). This trial marks the first patient dosing and aims to assess the safety and efficacy of the treatment. The company is building on its existing prostate cancer programs, including JANX007, which has shown promising early results.
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JANX Apr 1, 2026JANXGeneral
Janux Therapeutics Announces Development Candidate Nomination Under Bristol Myers Squibb Collaboration, Triggering $35 Million Milestone Payment
Janux Therapeutics has announced the nomination of a development candidate under its collaboration with Bristol Myers Squibb. This milestone achievement has triggered a $35 million payment. The candidate utilizes Janux's TRACTr platform to target a specific solid tumor antigen, marking a significant advancement in their immunotherapy pipeline.
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JANX Feb 27, 2026JANXGeneral
Janux Therapeutics Reports Fourth Quarter and Full Year 2025 Financial Results and Business Highlights
Janux Therapeutics reported its financial results for Q4 and full year 2025, highlighting significant advancements in its clinical pipeline, particularly with JANX007 and JANX008. The company has formed a strategic collaboration with Bristol Myers Squibb, which is expected to provide capital and validate its platform. Janux is focused on expanding its product candidates and enhancing its clinical strategy for future growth.
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JANX Feb 17, 2026JANXPhases
Janux Therapeutics Announces First Patient Dosed in Phase 1 Study of JANX011
Janux Therapeutics has announced the dosing of the first participant in a Phase 1 clinical study of JANX011, a bispecific targeting CD19 for autoimmune diseases. This study aims to evaluate the safety and pharmacodynamics of JANX011, which has shown promising preclinical results. The ARM platform may offer advantages over conventional therapies, with potential applications in hematologic malignancies as well.
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JANX Jan 22, 2026JANXGeneral
▲ +14.1%on this news
Janux Therapeutics Announces Collaboration and Exclusive Worldwide License Agreement with Bristol Myers Squibb to Develop a Novel Tumor-Activated Therapeutic for Solid Tumors
Janux Therapeutics has entered into a collaboration and exclusive license agreement with Bristol Myers Squibb to develop a novel tumor-activated therapeutic for solid tumors. This partnership aims to leverage Janux's proprietary technology and Bristol's expertise to accelerate the delivery of new treatments. Janux will handle preclinical development, while Bristol will manage IND submission and commercialization, with potential financial benefits of up to $800 million.
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JANX Dec 24, 2025JANXPhases
Janux Therapeutics Provides Program Update on Ongoing Phase 1 JANX008 Study
Janux Therapeutics has provided an update on its ongoing Phase 1 study of JANX008, an EGFR-targeted TRACTr for various solid tumors. The study has completed its dose-escalation phase and is now moving into expansion cohorts for further evaluation. Janux plans to share more updates as the study progresses.
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JANX Dec 2, 2025JANXPhases
▼ -53.3%on this news
Janux Announces Encouraging Efficacy and Safety Profile from Ongoing Phase 1 Clinical Trial for JANX007 in mCRPC
Janux Therapeutics announced positive interim data from its Phase 1 clinical trial of JANX007, a PSMA-directed TRACTr for mCRPC. The trial showed durable responses and a manageable safety profile, with high PSA response rates. The company is exploring further applications of JANX007 in earlier-line treatments and in combination therapies.
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JANX Nov 6, 2025JANXGeneral
Janux Therapeutics Reports Third Quarter 2025 Financial Results and Business Highlights • Enrollment ongoing for JANX007 and JANX008 • Updates on JANX007 and JANX008 expected in the fourth quarter of 2025 &
Janux Therapeutics reported its third quarter 2025 financial results, showing ongoing enrollment in two clinical trials for its drug candidates JANX007 and JANX008. The company reported a strong cash position of $989 million, aiding its operational capabilities. Over the past year, Janux has reduced its net loss, which may reflect improved financial management. However, increased research and development costs and the challenges of upcoming clinical trials present risks to the company’s outlook.
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JANX Aug 7, 2025JANXGeneral
▼ -6.6%on this news
Janux Therapeutics Reports Second Quarter 2025 Financial Results and Business Highlights • R&D Day highlighted TRACTr, TRACIr, and ARM pipeline progress and best-in-class potential of novel bispecific ARM platform
Janux Therapeutics reported its financial results for Q2 2025, highlighting advancements in its TRACTr, TRACIr, and ARM pipelines, which target various cancers and autoimmune diseases. Key updates include ongoing enrollments in the clinical trials for JANX007 and JANX008, with first patient dosing in collaboration with Merck generating a $10 million milestone payment. Despite a strong cash position of $996 million, the company reported a net loss of $33.9 million for the quarter, reflecting increased research and development costs compared to the previous year.
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JANX May 8, 2025JANXPhases
Janux Therapeutics Reports First Quarter 2025 Financial Results and Business Highlights • Phase 1b expansion study initiated with JANX007 in taxane-na ve mCRPC patients • Updated JANX007 data from Phase 1a
Janux Therapeutics reported its first-quarter 2025 financial results, highlighting the initiation of a Phase 1b expansion study for its drug JANX007 in patients with taxane-naïve metastatic castration-resistant prostate cancer (mCRPC). Updated results from the Phase 1a trial showed promising median progression-free survival, with median rates slightly improving. The company maintains a robust financial position, with over $1 billion in cash and equivalents, and plans to present additional data later in the year.
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JANX Feb 27, 2025JANXPhases
Janux Therapeutics Reports Fourth Quarter and Full Year 2024 Financial Results and Business Highlights • Recently presented positive Phase 1 clinical trial data for PSMA-TRACTr JANX007 in mCRPC • Enrollment
Janux Therapeutics reported positive financial results and business highlights for Q4 and full year 2024. The company presented encouraging Phase 1 clinical trial data for its drug JANX007, showing significant prostate-specific antigen response rates and durable declines in mCRPC patients. With a strong cash position of $1.03 billion, Janux is positioned to advance its clinical development plans and upcoming R&D activities slated for 2025. Progress on clinical trials for both JANX007 and JANX008 is ongoing, with further data updates expected next year.
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JANX Dec 3, 2024JANXGeneral
▲ +49%on this news
Janux Therapeutics Announces Proposed Public Offering
Janux Therapeutics has announced a proposed public offering of $300 million in shares of its common stock, with an additional option for underwriters to purchase up to $45 million more. The company plans to use the proceeds to advance its clinical development programs. Janux's proprietary technology focuses on tumor-activated immunotherapies, which aim to treat various solid tumors while minimizing safety concerns. However, the offering's success hinges on market conditions and other factors.
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JANX Dec 2, 2024JANXPhases
▼ -11.1%on this news· ran to +47% by day 3shared move
Janux Announces Doses Selected for Phase 1b Expansion Trials Supported by Encouraging Efficacy and Safety Profile Observed in Phase 1a Dose Escalation for JANX007 in mCRPC • Emerging JANX007 data demonstrated subs
Janux Therapeutics has selected doses for Phase 1b expansion trials of its JANX007 therapy, which has shown substantial clinical activity in patients with metastatic castration-resistant prostate cancer (mCRPC). In a Phase 1a trial, 100% of patients exhibited PSA50 declines, with a majority achieving deeper and durable responses. The safety profile of JANX007 appears favorable, primarily involving low-grade adverse events. As Janux moves forward into more advanced trials, they highlight a substantial unmet need for this patient population.
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JANX Nov 6, 2024JANXPhases
Janux Therapeutics Reports Third Quarter 2024 Financial Results and Business Highlights • Enrollment ongoing for PSMA-TRACTr (JANX007) in prostate cancer and EGFR-TRACTr (JANX008) in solid tumors • Update o
Janux Therapeutics announced its third quarter 2024 financial results, highlighting ongoing enrollment in its clinical trials for the PSMA-TRACTr (JANX007) and EGFR-TRACTr (JANX008). The company reported $658 million in cash and equivalents and a net loss of $28.1 million for the quarter, representing a significant increase compared to the previous year. Looking ahead, Janux anticipates updates on its JANX007 program by the end of the year, with further expansions planned for both clinical trials in the coming years.
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JANX Aug 7, 2024JANXPhases
Janux Therapeutics Reports Second Quarter 2024 Financial Results and Business Highlights • Enrollment ongoing for PSMA-TRACTr (JANX007) in prostate cancer and EGFR-TRACTr (JANX008) in solid tumors • Update
Janux Therapeutics reported strong financial results for Q2 2024, showing solid cash reserves of $646.3 million and ongoing clinical trials for its cancer therapies JANX007 and JANX008. The company received a $7.5 million milestone payment from Merck, further underscoring its partnership strengths. Recent appointments to the board are viewed as strategic moves to bolster leadership. However, the announcement acknowledged potential risks associated with clinical trial outcomes and regulatory approvals.
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JANX Jul 22, 2024JANXGeneral
▲ +6.8%on this news
Janux Therapeutics Announces Updates to Board of Directors • The appointment of Eric Dobmeier and Natasha Hernday to the Board brings extensive operational and business development experience to support corporate
Janux Therapeutics has appointed Eric Dobmeier and Natasha Hernday to its Board of Directors, enhancing its strategic capabilities in drug development. Dobmeier brings over 20 years of biopharmaceutical experience, having led a company through a significant acquisition. Hernday has a proven track record in securing high-value partnerships and business development. The company also announced the resignation of Jay Lichter and the appointment of Ronald Barrett as Chairperson, reflecting ongoing changes in leadership as Janux advances its clinical pipeline.
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JANX May 7, 2024JANXPhases
Janux Therapeutics Reports First Quarter 2024 Financial Results and Business Highlights • Enrollment ongoing for PSMA-TRACTr (JANX007) in prostate cancer • Enrollment ongoing for EGFR-TRACTr (JANX008) in so
Janux Therapeutics has announced its financial results for the first quarter of 2024, revealing a cash balance of $651.8 million. The company is currently progressing with enrollment for two clinical trials, JANX007 and JANX008, targeting prostate cancer and solid tumors. As part of its business strategy, Janux anticipates further updates on clinical data in the latter half of 2024. The company reported a reduced net loss compared to the previous year, reflecting improved financial management.
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JANX Mar 8, 2024JANXPhases
Janux Therapeutics Reports Fourth Quarter and Full Year 2023 Financial Results and Business Highlights • Recently presented positive Phase 1 clinical trial data for PSMA-TRACTr JANX007 in mCRPC and for EGFR-TRACTr
Janux Therapeutics announced its financial results for Q4 and the full year of 2023, highlighting positive Phase 1 clinical trial data for its drugs JANX007 and JANX008. The company reported a year-end cash position of $344 million and raised approximately $320.2 million in a recent underwritten offering. Key program milestones include ongoing enrollment in Phase 1 trials, with an update on data for JANX007 expected in the second half of 2024. Despite a net loss of $58.3 million for the year, the firm remains optimistic about its potential to address cancer treatment needs.
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JANX Feb 27, 2024JANXGeneral
▲ +229.5%on this news
Janux Therapeutics Announces Proposed Public Offering of Common Stock
Janux Therapeutics has announced a proposed public offering of $175 million in common stock to support its clinical development and general corporate purposes. The offering is subject to market conditions, and the company expects to grant underwriters an option to purchase additional shares. Janux aims to use the proceeds to further its internal product pipeline targeting various cancers with its proprietary immunotherapy technology. The company's TRACTr and TRACIr platforms are currently focused on several therapeutic candidates in clinical development.
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JANX Feb 26, 2024JANXPhases
Janux Announces Encouraging Safety and Efficacy Data in Ongoing Dose Escalation Trials for PSMAxCD3-TRACTr JANX007 in mCRPC and EGFRxCD3-TRACTr JANX008 in Solid Tumors • Emerging JANX007 data illustrate a potentia
Janux Therapeutics has announced positive interim clinical data for its TRACTr candidates, JANX007 and JANX008, which are being investigated for metastatic castration-resistant prostate cancer and solid tumors, respectively. The data reveal promising efficacy and a favorable safety profile, with significant PSA50 declines observed in patients treated with JANX007. Additionally, JANX008 demonstrated a partial response in a patient with non-small cell lung cancer, reinforcing its potential. The company plans to continue dose escalation trials to further evaluate the treatments.
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JANX Nov 7, 2023JANXPhases
Janux Therapeutics Reports Third Quarter 2023 Financial Results and Business Highlights • Enrollment ongoing for PSMA-TRACTr (JANX007) in prostate cancer • Enrollment ongoing for EGFR-TRACTr (JANX008) in so
Janux Therapeutics reported its financial results for the third quarter of 2023, highlighting ongoing enrollment in two Phase 1 clinical trials for its PSMA-TRACTr (JANX007) and EGFR-TRACTr (JANX008) programs. The company maintains a strong cash position of $349.7 million, projected to support operations through 2027. Financially, Janux reported a reduced net loss of $11.6 million compared to the previous year's quarter, reflecting improved operational efficiency. Future clinical updates are anticipated in 2024, signaling ongoing development and potential advancements in cancer therapies.
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JANX Aug 8, 2023JANXPhases
Janux Therapeutics Reports Second Quarter 2023 Financial Results and Business Highlights - Presented positive interim Phase 1 clinical trial data for PSMA-TRACTr JANX007 in prostate cancer - Management team bolstered wit
Janux Therapeutics has reported encouraging interim Phase 1 clinical trial results for its PSMA-TRACTr JANX007 in prostate cancer. The company has strengthened its financial outlook with an additional $60 million funding and enhanced its management team. Despite a net loss of $17.5 million for the second quarter of 2023, Janux remains optimistic about advancing its pipeline of cancer therapies. The firm continues to explore its TRACTr and TRACIr technologies for cancer treatment.
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JANX Jul 17, 2023JANXGeneral
Janux Therapeutics Announces Pricing of $60 Million Underwritten Offering of Common Stock and Pre-Funded Warrants
Janux Therapeutics announced a $60 million underwritten offering of common stock and pre-funded warrants to enhance its capital for the development of its immunotherapy pipeline. The offering includes 4,153,717 shares priced at $12.46 each, along with pre-funded warrants at $12.459 each. The offering is expected to close around July 19, 2023, but is subject to customary closing conditions. BofA Securities, Inc. is acting as the sole book-runner for the offering.
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JANX Jul 17, 2023JANXPhases
Janux Therapeutics Announces Positive Interim Clinical Data from Phase 1a Dose Escalation for PSMA-TRACTr JANX007 and an Update on Pipeline Programs Multiple patients treated with PSMA-TRACTr JANX007 have achieved meanin
Janux Therapeutics announced positive interim clinical data for its PSMA-TRACTr JANX007 in a Phase 1a trial for metastatic castration-resistant prostate cancer. The data indicated significant PSA reductions in several patients, coupled with low-grade and transient cytokine release syndrome. The treatment demonstrated a favorable safety profile, with no dose-limiting toxicities observed. The company expressed confidence in the ongoing development of JANX007 and outlined additional clinical programs in its pipeline.
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JANX May 9, 2023JANXPhases
Janux Therapeutics Reports First Quarter 2023 Financial Results and Business Highlights -First patient dosed with EGFR-TRACTr (JANX008) in first-in-human Phase 1 clinical trial in patients with solid tumors- -Interim cli
Janux Therapeutics reported its financial results for Q1 2023, highlighting key advancements in its clinical trials. Most notably, the company dosed its first patient with the EGFR-TRACTr (JANX008) in a Phase 1 trial for solid tumors. The financials reflected a net loss of $17.5 million, up from $13.4 million during the same period in the previous year. With $316.9 million in cash reserves, Janux continues to prioritize its TRACTr and TRACIr platforms for future development.
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JANX Mar 10, 2023JANXPhases
Janux Therapeutics Reports Fourth Quarter and Full Year 2022 Financial Results and Business Highlights -Interim clinical update from Phase 1 trial of JANX007 expected in 2H 2023- -FDA clearance granted for Investigationa
Janux Therapeutics reported its financial results for Q4 and the full year 2022, highlighting a robust cash position of $327 million. The company received FDA clearance for its EGFR-TRACTr IND application and is actively enrolling patients in the Phase 1 trial for its PSMA-TRACTr candidate. Upcoming milestones include an expected interim update from the JANX007 trial in the second half of 2023. Janux's leadership emphasized its commitment to advancing its immunotherapy pipeline amidst recent industry challenges.
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JANX Nov 10, 2022JANXPhases
▲ +8.3%on this news
Janux Therapeutics Reports Third Quarter 2022 Financial Results and Business Highlights -First patient dosed with JANX007 in first-in-human Phase 1 clinical trial in prostate cancer patients- -Interim clinical update fro
Janux Therapeutics Reports Third Quarter 2022 Financial Results and Business Highlights
-First patient dosed with JANX007 in first-in-human Phase 1 clinical trial in prostate cancer patients-
-Interim clinical update from Phase 1 trial of JANX007 expected in 2H 2023-
-IND appl
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JANX Sep 22, 2022JANXGeneral
Janux Therapeutics Appoints Winston Kung to Board of Directors
Janux Therapeutics Appoints Winston Kung to Board of Directors
SAN DIEGO, September 22, 2022 Janux Therapeutics, Inc. (Nasdaq: JANX) (Janux), a biopharmaceutical company developing a broad pipeline of novel immunotherapies by applying its proprietary technology to its Tumor Acti
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JANX Aug 9, 2022JANXFDA Updates
▼ -9.7%on this news
Janux Therapeutics Reports Second Quarter 2022 Financial Results and Business Highlights -IND application cleared for lead product candidate JANX007 (PSMA-TRACTr)- -Phase 1 clinical trial evaluating JANX007 for metastati
Janux Therapeutics Reports Second Quarter 2022 Financial Results and Business Highlights
-IND application cleared for lead product candidate JANX007 (PSMA-TRACTr)-
-Phase 1 clinical trial evaluating JANX007 for metastatic castration-resistant prostate cancer remains on-track to
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JANX May 10, 2022JANXGeneral
▲ +5%on this news
Janux Therapeutics Reports First Quarter 2022 Financial Results and Business Highlights -IND application recently submitted for PSMA-TRACTr (JANX007)- -Company remains on-track to submit IND application for EGFR-TRACTr (
Janux Therapeutics Reports First Quarter 2022 Financial Results and Business Highlights
-IND application recently submitted for PSMA-TRACTr (JANX007)-
-Company remains on-track to submit IND application for EGFR-TRACTr (JANX008) in 2H 2022-
-Merck nominates second target as pa
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JANX Mar 18, 2022JANXGeneral
Janux Therapeutics Provides Business Update and Reports Fourth Quarter and Full Year 2021 Financial Results -Company remains on-track to submit IND filings for two programs in 2022- -Company nominated its first TRACIr de
Janux Therapeutics Provides Business Update and Reports Fourth Quarter and Full Year 2021 Financial Results
-Company remains on-track to submit IND filings for two programs in 2022-
-Company nominated its first TRACIr development candidate, a PD-L1 x CD28 costimulatory bispecif
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JANX Nov 9, 2021JANXGeneral
▼ -6.9%on this news
Janux Therapeutics Reports Business Highlights and Third Quarter 2021 Financial Results -Company remains on-track to submit IND filings for two programs in 2022- -Board of Directors strengthened with key appointments- -$
Janux Therapeutics Reports Business Highlights and Third Quarter 2021 Financial Results
-Company remains on-track to submit IND filings for two programs in 2022-
-Board of Directors strengthened with key appointments-
-$387.5 million in cash and cash equivalents and short-term
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JANX Aug 10, 2021JANXGeneral
Janux Therapeutics Reports Second Quarter 2021 Financial Results -Successful $222.9 million IPO in June brings total funds raised in the quarter to $347.9 million- -Company on-track to submit IND filings for multiple pro
Janux Therapeutics Reports Second Quarter 2021 Financial Results
-Successful $222.9 million IPO in June brings total funds raised in the quarter to $347.9 million-
-Company on-track to submit IND filings for multiple programs in 2022-
-Management team strengthened with key app
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JANX Jun 15, 2021JANXGeneral
Janux Therapeutics Announces Closing of Initial Public Offering and Full Exercise of Underwriters Option to Purchase Additional Shares La Jolla, CA
Janux Therapeutics Announces Closing of Initial Public Offering and Full Exercise of Underwriters
Option to Purchase Additional Shares
La Jolla, CA, June 15, 2021 Janux Therapeutics, Inc. (Nasdaq: JANX) (Janux), a
biopharmaceutical company developing novel T cell engager immun
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