Recent Updates
Recently added Catalysts

Upcoming Catalyst

Drug Pipeline Intelligence

Clinical Trial Results

Inside Trades

Options Data

News Section

Hedge Funds

Ownership Trends

Competitive Position

Werewolf Therapeutics, Inc.

$0.35

-0.01 (-1.92%)

D 39Pipeline Score Undervalued Pharma · Commercial
Market Cap
21.56 M
EPS
-1.21
P/E Ratio
-
Value Trade
160.24 K
SEC Financials
Q1 2026
  • Dilution Risk

    40%
  • R&D Expenses

    8.18 M

  • Operating CF

    -10.60 M


  • Total Assets

    58.02 M

  • Total Liabilities

    45.82 M

  • Equity

    12.20 M

  • D/E Ratio

    12,345

-17.85 %
Week
-51.42 %
1 Month
-38.81 %
3 Month
-47.43 %
6 Month
-96.38 %
5 Year
-97.56 %
All Time
Cash Data
Caution
  • Cash Position

    46.45 M

  • Monthly Burn

    3.53 M

  • Runway

    11.6 mo

  • Burn Trend

    Decelerating
  • SEC Filing

    May 7, 2026
Overview
Volume
1.36 M
52 Week Range
0.40 - 2.38
% held by Insiders
17.5 %
% held by Institutions
19.03 %
Enterprise Value
12.76 M
Total Shares
48.62 M
Short %
2.41 %
Float Shares
36.17 M
Company Description
HQ: 200 TALCOTT AVENUE, WATERTOWN,...
Employees:14

locked

Upcoming Catalyst
Catalyst Drug/Treatment Stage Probability of Approval Description Drug Type Therapeutic Area Source
Example Drug Treatment for example condition requiring FDA review
Phase 3
-%
Small Molecule
Oncology
Example Drug Treatment for example condition requiring FDA review
Phase 3
-%
Small Molecule
Oncology
Example Drug Treatment for example condition requiring FDA review
Phase 3
-%
Small Molecule
Oncology
Unlock Upcoming Catalyst data

Catalyst Timeline

Dated clinical, regulatory & corporate events for Werewolf Therapeutics, Inc.

234Total events
6Upcoming
19Tier-1 (high impact)
2021 – 2027Coverage

Upcoming catalysts 6

Q4 2026
T2Runway Guidance Update
Cash runway guidance: sufficient into Q4 2026
2027
T2IND Submission
IND filing planned for WTX-1011
WTX-1011STEAP1-expressing cancersPreclinical
2027
T2IND Submission
IND filing planned for WTX-2022
WTX-2022CDH6-expressing cancersPreclinical
Jun 2027
T2IND Submission
IND for WTX-1011 anticipated in mid-2027
WTX-1011STEAP1+ cancers
Jun 2027
T2IND Submission
IND for WTX-2022 anticipated in mid-2027
WTX-2022CDH6+ cancers
2025-H2
T3Development Candidate Nomination
Nomination of an additional INDUCER candidate
preclinical

Event history 228

May 7, 2026
Partnership / LicenseJZP898Corporate
Asset purchase agreement with Jazz Pharmaceuticals for JZP898
IFN programsource ↗
May 7, 2026
Quarterly UpdateCorporate
First quarter 2026 financial results
May 6, 2026
Debt Royalty FinancingCorporate
Repayment of loan and security agreement with K2 HealthVentures
Q2 2026
Runway Guidance UpdateCorporate
Cash runway through at least Q2 2026
Mar 27, 2026
Quarterly UpdateCorporate
Reported Q4 and full year 2025 financial results
Mar 27, 2026
Pipeline PrioritizationCorporate
Initiated process to explore strategic alternatives including sale, merger, or licensing
Feb 24, 2026
Pipeline PrioritizationCorporate
Company announces exploration of strategic alternatives including sale, merger, or licensing
Q1 2026
Topline ReadoutWTX-124Clinical Data
Final Phase 1/1b data anticipated in 1H26
advanced/metastatic cancerssource ↗
Q1 2026
Topline ReadoutWTX-330Clinical Data
Phase 1b/2 update anticipated in 1H26
advanced/metastatic cancerssource ↗
Q1 2026
Trial CompletionWTX-124Trial
Phase 1/1b clinical trial expected to complete
solid tumorssource ↗
Q1 2026
Additional DataWTX-124Clinical Data
Additional data update for WTX-124
solid tumorssource ↗
Q1 2026
Primary CompletionWTX-330Trial
Completion of Part A of Phase 1b/2 clinical trial
solid tumorssource ↗
Drug Pipeline Intelligence
D39
Pipeline Score
$27M
Pipeline Value
Undervalued
Valuation Signal
2
Drugs Scored
4.2x
rNPV / MCap
Top 56%
Micro Cap
(rank 399 of 905)
Percentile Rank
Werewolf Therapeutics, Inc. faces pipeline headwinds (39/100), with $2.5B risk-adjusted pipeline value, led by WTX-124 in Metastatic Solid Tumor (Phase 1).
Showing 1 of 1 assets
DrugIndicationPhaseNCT IDPTRSrNPVStatusEnrollmentVelocityDesignCompletionML SignalLast Change
WTX-124
Small molecule
Metastatic Solid TumorPhase 1NCT054798125% $1.6B ACTIVE NOT_RECRUITING 150 AVERAGE C (41) Jul 31, 2026MODERATE_RISKLOW
May 26, 2026
Unlock Drug Pipeline Intelligence
Inside Trades
TREND
CORPORATE INSIDERS BOUGHT SHARES WORTH 1.8M IN THE LAST 3 MONTHS
YEARLY INSIDER TRANSACTIONS
Sector Avg.
INSIDERS
SOLD
INSIDERS
BOUGHT
POSITIVE SENTIMENT Based on 22 Insiders Transactions
Unlock Inside Trades data
Hedge Funds
TREND
HEDGE FUNDS INCREASED HOLDINGS BY 200.0K SHARES IN THE LAST QUARTER
Shares Held
2040.00B1530.00B1020.00B510.00B0
Q3
2024
Q4
2024
Q1
2025
Q2
2025
HEDGE FUNDS
SOLD
HEDGE FUNDS
BOUGHT
POSITIVE SENTIMENT Based on 27 hedge funds in the last quarter
18 buying (3 new)·9 selling (1 exited)·2 unchanged
Fund Count
60%
Share Volume
25%
Conviction
15%
HedgeFund Name
( 3 )
% of Portfolio Current MV
-
Shares Owned
-
Activity
Avg Price $0

Example Capital Management

2.5 %
15.00 M
250.00 K

Example Capital Management

2.5 %
15.00 M
250.00 K

Example Capital Management

2.5 %
15.00 M
250.00 K
Unlock Hedge Funds table data
Werewolf Therapeutics, Inc. (HOWL) Analyst Ratings & Price Targets
Symbol
Firm
Rating
Action
Price Target
Upside
date
HOWL
Example Securities
Buy
Initiated
$150.00
+25%
2026-01-15
HOWL
Example Securities
Buy
Initiated
$150.00
+25%
2026-01-15
HOWL
Example Securities
Buy
Initiated
$150.00
+25%
2026-01-15
Unlock Biotech Analyst Ratings data
HOWL Stock Forecast & Analyst Consensus
BUY
Analyst Ratings
Buy65.0%
Hold25.0%
Sell10.0%
Price Target Trend
Average$24.00
Low$18.00
High$32.00
Unlock Price Target Trend
HOWL Institutional Ownership Trends
Current Insider %
5.20%
+0.00%
Current Institutional %
62.40%
+0.00%
Total Ownership
67.60%
Insider + Institutional
Data Points
1
1 Ticker(s)
Option Chain Statistics
ExpirationVolumeOpen InterestImplied Volatility CallsImplied Volatility Puts
CallsPutsPut-Call RatioCallsPutsPut-Call RatioIVOiWaIvVWaIvIVOiWaIvVWaIv
2026-07-17 0.00 0 - - - - - -
2026-07-17 0.00 0 - - - - - -
2026-07-17 0.00 0 - - - - - -
Unlock Option Chain Statistics data
Option Chain
CallsStrikePuts
Last PriceVolumeOpen InterestLast PriceVolumeOpen Interest
No data available
Unlock Option Chain data
Unlock Options Chart data
Open interest
0 600K 1.2M 1.8M Avg OI 1.00 M Open Interest
0 1 2 3 1.1 Put-Call Ratio
Today's Open Interest
1.00 M
Put-Call Ratio
1.1
Put Open Interest
480.00 K
Call Open Interest
520.00 K
Open Interest Avg (30-day)
900,000
Today vs Open Interest Avg (30-day)
11.11%
Option Volume
0 450K 900K 1.4M Avg OV 750.00 K Option Volume
0 1 2 3 0.95 Put-Call Ratio
Today's Volume
750.00 K
Put-Call Ratio
0.95
Put Volume
360.00 K
Call Volume
390.00 K
Volume Avg (30-day)
800,000
Today vs Volume Avg (30-day)
-6.25%
Company News
HOWL
May 7, 2026
HOWLGeneral

Werewolf Therapeutics Reports First Quarter 2026 Financial Results and Recent Corporate Updates - Company continues to evaluate strategic options to maximize shareholder value - Watertown, Mass.

Werewolf Therapeutics has released its first-quarter financial results for 2026, demonstrating a reduced net loss of $13.5 million compared to $18.1 million in the prior year. The company is actively exploring strategic options aimed at maximizing shareholder value, including a successful asset purchase agreement with Jazz Pharmaceuticals for the JZP898 program. However, its cash position has declined to $46.5 million from $57.1 million in the last quarter. Ongoing uncertainties surrounding the development of its product candidates were also noted.

Read more →
HOWL
Mar 27, 2026
HOWLGeneral

Werewolf Therapeutics Reports Fourth Quarter and Full Year 2025 Financial Results and Recent Corporate Updates

Werewolf Therapeutics reported its fourth quarter and full year 2025 financial results, highlighting a strategic evaluation process to maximize stockholder value. The company has engaged Piper Sandler as a financial advisor for potential transactions. Financially, the company showed a decrease in both research and development expenses and net loss compared to 2024.

Read more →
HOWL
Feb 25, 2026
HOWLGeneral

Werewolf Therapeutics Announces Plan to Explore Strategic Alternatives

Werewolf Therapeutics announced plans to explore various strategic alternatives aimed at maximizing stockholder value. The company has engaged Piper Sandler & Co. as its financial advisor for this process. Potential options include a sale of the company, mergers, or collaborations, although no specific timeline or guarantees for success have been provided.

Read more →
HOWL
Dec 18, 2025
HOWLPhases

Werewolf Therapeutics Announces Pipeline and Business Updates

Werewolf Therapeutics has announced significant advancements in its clinical pipeline, particularly for its candidates WTX-124 and WTX-330. Initial data from the WTX-124 Phase 1b trial indicates a 30% overall response rate as a monotherapy in a specific subset of melanoma patients. Additionally, Phase 1b/2 data for WTX-330 suggests promising tolerability and antitumor activity. The company is focused on securing strategic partnerships for further development and anticipates completing trials for both candidates by mid-2026.

Read more →
HOWL
Dec 18, 2025
HOWLGeneral

Corporate Presentation December 2025 1 | 2025 WEREWOLF THERAPEUTICS 2025 WEREWOLF THERAPEUTICS Cautionary Note Regarding Forward-Looking Statements This presentation contains forward-looking statements that involve subst

Werewolf Therapeutics presented forward-looking statements regarding its pipeline and future operations, highlighting key product candidates including WTX-124 and WTX-330, which are in clinical development. The presentation emphasized the company's innovative PREDATOR platform, showcasing its potential to address limitations in existing cancer immunotherapies. Strategic partnerships are being sought to bolster drug development, with notable preliminary clinical trial data suggesting promising safety and efficacy outcomes. However, the company acknowledges the inherent uncertainties of clinical trials and the need for regulatory approvals.

Read more →
HOWL
Nov 7, 2025
HOWLConferences/Events

Werewolf Therapeutics Presents Data Expanding Its PREDATOR® Platform at the Society for Immunotherapy of Cancer’s (SITC) 40th Annual Meeting

Werewolf Therapeutics presented promising preclinical data at the SITC 40th Annual Meeting, showcasing its PREDATOR platform. The data highlighted a sequential dosing regimen that enhances antitumor activity while minimizing systemic toxicities. Additionally, the first real-time pharmacokinetic data for WTX-124 confirmed its selective activation in tumor environments, supporting ongoing clinical trials.

Read more →
HOWL
Nov 4, 2025
HOWLPhases

Werewolf Therapeutics Reports Third Quarter 2025 Financial Results and Provides Business Update

Werewolf Therapeutics reported its third quarter 2025 financial results, highlighting advancements in its clinical programs, particularly WTX-124 and WTX-330. The company plans to provide updates on these programs and its first INDUCER candidate, WTX-1011, later in the fourth quarter. WTX-124 has received Fast Track Designation, indicating progress towards registration-enabling trials.

Read more →
HOWL
Oct 8, 2025
HOWLFDA Updates

Werewolf Therapeutics Receives Fast Track Designation from the U.S. FDA for WTX-124, an Investigational Therapy for the Treatment of Cancer

Werewolf Therapeutics has received Fast Track Designation from the FDA for WTX-124, an investigational therapy aimed at treating advanced cutaneous melanoma. This designation is intended to expedite the development of drugs addressing serious unmet medical needs. The company is currently evaluating WTX-124 in a Phase 1/1b clinical trial, with preliminary data expected soon.

Read more →
HOWL
Oct 3, 2025
HOWLConferences/Events

Werewolf Therapeutics to Present Posters at the Society for Immunotherapy of Cancer’s (SITC) 40th Annual Meeting

Werewolf Therapeutics, Inc. announced the presentation of three posters at the Society for Immunotherapy of Cancer's 40th Annual Meeting, scheduled for November 5-9, 2025. The posters will showcase research on their conditionally activated therapeutics aimed at enhancing antitumor activity while minimizing toxicity. This highlights the company's commitment to advancing cancer treatment through innovative approaches.

Read more →
HOWL
Sep 2, 2025
HOWLConferences/Events

Werewolf Therapeutics to Participate in the Upcoming H.C. Wainwright 27th Annual Global Investment Conference

Werewolf Therapeutics will participate in the H.C. Wainwright 27th Annual Global Investment Conference on September 8, 2025. CEO Daniel J. Hicklin and CMO Randi Isaacs will engage in a fireside chat to discuss the company's innovative therapies. The event will be available via live webcast and archived for 90 days.

Read more →
HOWL
Aug 14, 2025
HOWLPhases

Werewolf Therapeutics Reports Second Quarter 2025 Financial Results and Provides Business Update - WTX-124 Phase 1 1b clinical trial on track for interim data readout in the fourth quarter of 2025, including patients in

Werewolf Therapeutics reported its financial results for Q2 2025, highlighting the positive progress of the WTX-124 Phase 1 1b clinical trial, which is set for interim data readout in Q4 2025. The company plans to engage the FDA to discuss potential registrational pathways for WTX-124 in advanced cutaneous melanoma. Additionally, Werewolf introduced WTX-1011, a new T-cell engager candidate for treating prostate cancer. However, the company's financial outlook shows a net loss of $18 million and a reduction in cash reserves over the last quarter.

Read more →
HOWL
Jul 9, 2025
HOWLConferences/Events

Werewolf Therapeutics to Participate in the KidneyCAN 7th Annual Kidney Cancer Research Summit

Werewolf Therapeutics will present at the KidneyCAN 7th Annual Kidney Cancer Research Summit on July 17-18, 2025. Dr. Randi Isaacs will discuss the company's WTX-124, a tumor-activated IL-2 INDUKINE molecule aimed at enhancing immune response in renal cell carcinoma. The presentation will highlight early clinical findings and the ongoing national trials for advanced or metastatic RCC.

Read more →
HOWL
Jun 12, 2025
HOWLConferences/Events

Werewolf Therapeutics to Participate in the BIO International Convention

Werewolf Therapeutics will participate in the BIO International Convention from June 16-19, 2025, where Dr. Randi Isaacs will discuss conditionally activated biologics. This innovative approach aims to enhance anti-tumor activity while reducing toxicity. The company also launches the 'Full Moon Moment' initiative to promote its clinical trials, including the promising WTX-124 molecule.

Read more →
HOWL
May 29, 2025
HOWLConferences/Events

Werewolf Therapeutics to Participate in the Upcoming Jefferies Global Healthcare Conference

Werewolf Therapeutics, Inc. will participate in the Jefferies Global Healthcare Conference from June 3-5, 2025. CEO Daniel J. Hicklin and CMO Randi Isaacs will engage in a fireside chat on June 5 at 4:20 PM EDT. The event will be accessible via a live webcast and archived for 90 days.

Read more →
HOWL
May 13, 2025
HOWLConferences/Events

Werewolf Therapeutics to Participate in Hanson Wade’s 6th Annual Cytokine-Based Drug Development Summit

Werewolf Therapeutics, Inc. announced its participation in the 6th Annual Cytokine-Based Drug Development Summit, where Sameer Chopra, M.D., Ph.D., will present data on their IL-2 and IL-12 INDUKINE molecules. The presentation will focus on the successful validation of these immunotherapies in clinical trials. Werewolf's approach aims to selectively activate treatments in the tumor microenvironment, potentially improving therapeutic outcomes for cancer patients.

Read more →
HOWL
May 8, 2025
HOWLPhases

Werewolf Therapeutics Reports First Quarter 2025 Financial Results and Provides Business Update - WTX-124 Phase 1 1b clinical trial on track for data readouts and interactions with the FDA in the second half of the year

Werewolf Therapeutics has reported its financial results for the first quarter of 2025 and provided a business update. The company is on track in its WTX-124 Phase 1 1b trial, with plans for interim data presentation and FDA engagement later this year. Additionally, the WTX-330 Phase 1b 2 trial has commenced, aiming to optimize the therapeutic exposure in the tumor microenvironment. Despite a net loss reported for the quarter, Werewolf's cash guidance suggests operational effectiveness until late 2026 as it advances its clinical programs and pipeline development.

Read more →
HOWL
May 5, 2025
HOWLConferences/Events

Werewolf Therapeutics to Participate in Upcoming Investor Conferences

Werewolf Therapeutics, Inc. announced its participation in two upcoming investor conferences in May 2025. The events include the Citizens Life Sciences Conference on May 8 and the Bank of America Securities Health Care Conference on May 14. Management will be involved in fireside chats at both conferences, providing insights into the company's innovative approach in developing therapeutic solutions using their proprietary PREDATOR® platform. The company's work focuses on conditionally activated therapeutics for cancer and immune-mediated conditions.

Read more →
HOWL
May 5, 2025
HOWLConferences/Events

Werewolf Therapeutics Presents New Preclinical Data Further Characterizing its IL-10 INDUKINE Molecule, WTX-921, for the Treatment of Inflammatory Bowel Disease (IBD) at AAI Annual Meeting

Werewolf Therapeutics has presented new preclinical data on its IL-10 INDUKINE molecule, WTX-921, for treating Inflammatory Bowel Disease (IBD) at the AAI Annual Meeting. The results show that WTX-921 effectively reduced inflammation in a mouse model, offering insights into its mechanism of action. The molecule is engineered to specifically target inflamed colon tissue while minimizing off-target effects associated with systemic IL-10 therapy. This advancement could provide significant benefits for IBD patients, enhancing treatment efficacy while reducing adverse reactions.

Read more →
HOWL
Apr 17, 2025
HOWLGeneral

Werewolf Therapeutics Appoints Steven Bloom as Chief Business Officer

Werewolf Therapeutics has appointed Steven Bloom as its Chief Business Officer, bringing over 35 years of experience in the life sciences sector. Bloom's expertise is anticipated to enhance the company's corporate strategy at a pivotal time, with upcoming clinical trial data from WTX-124 expected to inform regulatory discussions. Werewolf continues to advance its PREDATOR platform, while Bloom is set to leverage his previous experiences to guide the organization in business development and growth initiatives. The company remains focused on pioneering immune-mediated cancer treatments with its innovative therapeutic technologies.

Read more →
HOWL
Mar 31, 2025
HOWLConferences/Events

Werewolf Therapeutics to Present at the 24th Annual Needham Virtual Healthcare Conference

Werewolf Therapeutics, Inc. announced that its executives will present at the 24th Annual Needham Virtual Healthcare Conference on April 7, 2025. This presentation will highlight the company's innovative approach to developing conditionally activated therapeutics aimed at enhancing immune response for cancer treatment. The event underscores Werewolf's commitment to advancing its clinical candidates, WTX-124 and WTX-330, designed to selectively activate in the tumor microenvironment. A live webcast and subsequently archived playback will be available for those interested in the presentation.

Read more →
HOWL
Mar 11, 2025
HOWLPhases

Werewolf Therapeutics Reports Fourth Quarter and Full Year 2024 Financial Results and Provides Business Update - Full enrollment in cutaneous melanoma dose-expansion arms of Phase 1 1b clinical trial evaluating WTX-124 a

Werewolf Therapeutics has reported its financial results for Q4 and the full year 2024, highlighting significant progress in its clinical trials. The company expects full enrollment in dose-expansion arms for their WTX-124 melanoma therapy by the end of 2025 and plans to discuss registrational pathways with the FDA. However, the company also reported an increased net loss and a significant drop in collaboration revenue year-over-year. Overall, the data suggests a focus on advancing their clinical development amidst financial challenges.

Read more →
HOWL
Mar 4, 2025
HOWLConferences/Events

Werewolf Therapeutics to Present at the 2025 Leerink Partners Global Biopharma Conference

Werewolf Therapeutics, Inc. will present at the 2025 Leerink Partners Global Biopharma Conference in Miami from March 10-12, 2025. The company's leadership, including CEO Daniel J. Hicklin and CMO Randi Isaacs, will engage in a fireside chat on March 11, 2025. Werewolf specializes in developing conditionally activated therapeutics aimed at treating cancer and other immune-mediated conditions through its proprietary PREDATOR® platform.

Read more →
HOWL
Feb 24, 2025
HOWLGeneral

Werewolf Therapeutics Appoints Anil Singhal, Ph.D., to its Board of Directors

Werewolf Therapeutics, Inc. announced the appointment of Anil Singhal, Ph.D., to its board of directors, enhancing its leadership with his extensive experience in oncology. Dr. Singhal, who is the CEO of Trishula Therapeutics, expressed enthusiasm for advancing Werewolf's novel INDUKINE molecules for cancer treatment. Concurrently, the company noted that Derek DiRocco will resign from the board at the upcoming annual meeting. This leadership change comes at a pivotal time in Werewolf's development of innovative therapies aimed at stimulating the immune system.

Read more →
HOWL
Jan 13, 2025
HOWLPhases

Werewolf Therapeutics Provides Business Update and Highlights 2025 Strategic Outlook

Werewolf Therapeutics announced key updates regarding its clinical programs and strategic outlook for 2025. It expects interim data from its WTX-124 trials in monotherapy and combination settings in 2025, which will inform regulatory discussions. Additionally, the company plans to initiate Phase 1/2 trials for WTX-330, targeting immunotherapy-resistant cancers. Their financial position remains robust, projected to sustain operations through at least mid-2026.

Read more →
HOWL
Nov 20, 2024
HOWLConferences/Events

Werewolf Therapeutics to Participate in the 7th Annual Evercore ISI HealthCONx Healthcare Conference

Werewolf Therapeutics, Inc. announced its participation in the 7th Annual Evercore ISI HealthCONx Healthcare Conference. Executives Daniel J. Hicklin, Ph.D., and Randi Isaacs, M.D. will host a fireside chat on December 5, 2024. The conference takes place from December 3-5 in Miami, Florida, highlighting the company's advancements in conditionally activated therapeutics for cancer treatment. The live webcast of the chat will be available for investors and others interested in the company's progress.

Read more →
HOWL
Nov 12, 2024
HOWLGeneral

Delivering the Power of Immunotherapy CORPORATE PRESENTATION | November 2024 1 | 2024 WEREWOLF THERAPEUTICS Cautionary Statements This presentation contains forward-looking statements that involve substantial risks and u

Werewolf Therapeutics presented its corporate strategies and drug development plans for November 2024, focusing on its innovative cytokine therapies. The company aims to harness the potential of its next-generation products, particularly emphasizing the pipeline's promising candidates such as WTX-124. However, the presentation also outlines significant risks and uncertainties associated with drug development. The company is positioned well financially, with sufficient cash runway projected to support their operations through 2026.

Read more →
HOWL
Nov 7, 2024
HOWLPhases

Werewolf Therapeutics Presents Preclinical and Clinical Data at the Society for Immunotherapy of Cancer’s (SITC) 39th Annual Meeting

Werewolf Therapeutics presented both preclinical and interim phase 1 clinical trial data at the 2024 SITC Annual Meeting. The findings underscore the potential of WTX-330, a tumor-activated IL-12 prodrug, showcasing a favorable tolerability profile and encouraging signs of efficacy in patients with treatment-resistant solid tumors. Additionally, preclinical data highlighted the antitumor activity of INDUKINE molecules. The company plans to optimize further trials based on these promising results, with enrollment for a Phase 1/2 study expected in early 2025.

Read more →
HOWL
Nov 7, 2024
HOWLPhases

Werewolf Therapeutics Reports Third Quarter 2024 Financial Results and Provides Business Update - Interim data from ongoing Phase 1 clinical trial of WTX-330, further characterizing tolerability and activity profile, to

Werewolf Therapeutics reported its third quarter 2024 financial results, highlighting progress in clinical trials for its candidates WTX-124 and WTX-330. Interim data for WTX-330 is to be presented at the SITC Annual Meeting, showcasing emerging tolerability and clinical activity. Additionally, the company introduced WTX-921, targeting inflammatory diseases, and updated its cash guidance to ensure funds through at least the second quarter of 2026. However, the company reported a net loss that has increased compared to the previous year, raising concerns about financial stability.

Read more →
HOWL
Oct 31, 2024
HOWLGeneral

Werewolf Therapeutics Announces Promising New Development Candidate, WTX-921, a first-of-its-kind IL-10 INDUKINE™ Molecule for Inflammatory Diseases

Werewolf Therapeutics has announced the addition of WTX-921, a novel IL-10 INDUKINE candidate, to its pipeline aimed at addressing inflammatory diseases, particularly Inflammatory Bowel Disease (IBD). This development signifies a strategic expansion of their innovative PREDATOR platform, which has previously shown promise in oncology applications. With IBD being a chronic condition characterized by considerable unmet needs, the company aims to leverage its unique drug design approach to improve treatment outcomes for patients. The advancement underscores Werewolf's commitment to exploring new therapeutic areas beyond oncology.

Read more →
HOWL
Oct 4, 2024
HOWLConferences/Events

Werewolf Therapeutics to Present Posters at the Society for Immunotherapy of Cancer’s (SITC) 39th Annual Meeting

Werewolf Therapeutics, Inc. has announced that it will present two posters at the Society for Immunotherapy of Cancer’s 39th Annual Meeting scheduled for November 6-10, 2024, in Houston, Texas. The posters will highlight data regarding their INDUKINE™ molecules and interim results from a Phase 1 study of their tumor-activated IL-12 prodrug, WTX-330. These presentations underscore the company's commitment to developing innovative cancer treatments through its proprietary therapeutic platforms.

Read more →
HOWL
Sep 3, 2024
HOWLConferences/Events

Werewolf Therapeutics to Participate in the H.C. Wainwright 26th Annual Global Investment Conference

Werewolf Therapeutics, Inc. has announced its participation in the H.C. Wainwright 26th Annual Global Investment Conference. Daniel J. Hicklin, Ph.D., and Randi Isaacs, M.D. will engage in a fireside chat on September 10, 2024. The conference runs from September 9-11, 2024, in New York City. The company focuses on developing therapeutics that activate the immune system specifically within the tumor microenvironment to aid cancer treatment.

Read more →
HOWL
Aug 8, 2024
HOWLPhases

Werewolf Therapeutics Reports Second Quarter 2024 Financial Results and Provides Business Update - Positive data from ongoing Phase 1 1b clinical trial of WTX-124 presented at American Society of Clinical Oncology (ASCO)

Werewolf Therapeutics reported positive interim data from its ongoing Phase 1b clinical trial of WTX-124 at the ASCO meeting, showing clinical activity and tolerable doses in patients. The company is also progressing WTX-330, demonstrating promising exposure levels and initial efficacy. Despite these positive developments, Werewolf’s financial report indicates a significant net loss and decreased collaboration revenue from the previous year. The company maintains a strong cash position but faces challenges in its revenue stream.

Read more →
HOWL
Jun 25, 2024
HOWLPhases

Werewolf Therapeutics Highlights Initial Safety and Efficacy Data from its Ongoing Phase 1 Clinical Trial Evaluating WTX-330 in Patients with Advanced or Metastatic Solid Tumors or Non-Hodgkin Lymphoma - Data demonstrate

Werewolf Therapeutics has announced promising initial results from its Phase 1 clinical trial evaluating WTX-330, an interleukin-12 therapy, in patients with advanced cancers. The data indicates encouraging safety and efficacy, with notable exposure levels and signs of clinical activity. Early results have shown an unconfirmed partial response in a metastatic melanoma patient. Officials from Werewolf express optimism about the future development of WTX-330, which could address challenges faced by patients resistant to standard immunotherapies.

Read more →
HOWL
Jun 3, 2024
HOWLPhases

Werewolf Therapeutics to Present Data from Ongoing Phase 1/1b Clinical Trial of WTX-124 as Monotherapy and in Combination with Pembrolizumab in Solid Tumors - WTX-124 was shown to be clinically active and generally well-

Werewolf Therapeutics announced positive results from its ongoing Phase 1/1b trial of WTX-124, which is being evaluated as a monotherapy and in combination with pembrolizumab for solid tumors. Data presented at the 2024 ASCO Annual Meeting highlighted clinical activity, with notable responses in patients who were previously treated with immune checkpoint inhibitors. The recommended dose for expansion has been selected, and enrollment for additional arms is underway. The findings suggest potential for WTX-124 as a best-in-class therapy with fewer toxicities compared to traditional high-dose IL-2 treatments.

Read more →
HOWL
Jun 1, 2024
HOWLPhases

Werewolf Therapeutics to Present Data from Ongoing Phase 1/1b Clinical Trial of WTX-124 as Monotherapy and in Combination with Pembrolizumab in Solid Tumors

Werewolf Therapeutics announced promising data from its Phase 1/1b clinical trial for WTX-124, a novel Interleukin-2 therapy, highlighting its clinical activity in patients resistant to checkpoint inhibitors. The drug showed three objective responses, one being a durable complete response, and was generally well-tolerated both as monotherapy and in combination with pembrolizumab. Following these results, the company has opened expansion arms for further testing in specific cancer types while continuing to refine dosing strategies. Detailed results will be shared during a webcast on June 3, 2024, after their presentation at the ASCO Annual Meeting.

Read more →
HOWL
May 30, 2024
HOWLConferences/Events

Werewolf Therapeutics to Participate at the Jefferies Global Healthcare Conference

Werewolf Therapeutics, Inc. (Nasdaq: HOWL) will participate in a fireside chat at the Jefferies Global Healthcare Conference on June 6, 2024. CEO Daniel J. Hicklin and CMO Randi Isaacs will represent the company during the event. The conference takes place in New York City from June 4-6, 2024. Werewolf is known for its conditionally activated immunotherapies aimed at treating cancer, specifically utilizing their proprietary PREDATOR™ platform.

Read more →
HOWL
May 23, 2024
HOWLPhases

Werewolf Therapeutics to Present Updated Data from Phase 1/1b Clinical Trial of WTX-124 as Monotherapy and in Combination with Pembrolizumab in Solid Tumors at 2024 ASCO Annual Meeting

Werewolf Therapeutics has announced upcoming presentations of updated clinical data on WTX-124 from its Phase 1/1b trial. The trial evaluates WTX-124 as both a monotherapy and in combination with pembrolizumab for patients with checkpoint therapy-resistant solid tumors. Initial findings indicate WTX-124 is well tolerated and shows clinical activity. Further details will be presented at the ASCO Annual Meeting from May 31 to June 4, 2024, in Chicago, Illinois.

Read more →
HOWL
May 3, 2024
HOWLPhases

Werewolf Therapeutics Reports First Quarter 2024 Financial Results and Provides Business Update - Company to present an update of its ongoing monotherapy and combination Phase 1 1b trial of WTX-124 in advanced or metasta

Werewolf Therapeutics reported its financial results for Q1 2024 and provided an update on its clinical programs. The company is set to present interim clinical data for its lead candidates WTX-124 and WTX-330 at upcoming ASCO and other meetings. Notably, Werewolf has extended its cash runway to the first quarter of 2026, although it reported an increased net loss compared to the prior year. Collaboration revenue has also decreased significantly during this period, indicating potential financial challenges ahead.

Read more →
HOWL
Apr 24, 2024
HOWLPhases

Werewolf Therapeutics Announces WTX-124 Clinical Abstract Accepted for Presentation at the 2024 American Society of Clinical Oncology (ASCO) Annual Meeting

Werewolf Therapeutics has announced that an abstract detailing their ongoing Phase 1/1b study of WTX-124 has been accepted for presentation at the 2024 ASCO Annual Meeting. This study involves investigating WTX-124, a conditionally activated interleukin 2 molecule, in patients with advanced or metastatic solid tumors following checkpoint inhibitor therapy. The presentation is scheduled for June 1, 2024. This update indicates progress in Werewolf's effort to leverage innovative immunotherapies for cancer treatment.

Read more →
HOWL
Apr 23, 2024
HOWLPhases

Werewolf Therapeutics Presents First Preclinical Data Highlighting IL-10 INDUKINE Molecules as a Potential Therapy for Inflammatory Bowel Disease (IBD) at AAI Annual Meeting

Werewolf Therapeutics announced the presentation of preclinical data at the AAI Annual Meeting, showcasing its IL-10 INDUKINE molecules for treating Inflammatory Bowel Disease (IBD). The findings indicate that these molecules can activate locally in inflamed colonic tissues, offering a novel therapeutic strategy. This represents an extension of Werewolf's PREDATOR platform from cancer treatment into immunology and inflammation. The data highlights the potential effectiveness in addressing issues faced by patients who do not respond to current IBD therapies.

Read more →
HOWL
Apr 5, 2024
HOWLPhases

Werewolf Therapeutics Presents Preclinical Results Demonstrating Anti-Tumor Effects of Pro-Inflammatory Cytokine Therapeutics WTX-518 and WTX-712 at AACR 2024 Annual Meeting

Werewolf Therapeutics presented promising preclinical data for its cytokine therapeutics WTX-518 and WTX-712 at the AACR 2024 Annual Meeting. WTX-518 showed complete tumor regression in animal models, while WTX-712 demonstrated strong anti-tumor effects through unique immune activation pathways. Both candidates are designed to selectively activate in the tumor microenvironment and could provide new options for treating refractory cancers. The findings highlight the potential innovations in the company's therapeutic strategies against cancer.

Read more →
HOWL
Apr 4, 2024
HOWLConferences/Events

Werewolf Therapeutics to Present First-of-Its-Kind Data Demonstrating Utility for PREDATOR™ Platform in Immunology-Based Diseases at AAI Annual Meeting

Werewolf Therapeutics announced that it will present data on its PREDATOR platform at the AAI Annual Meeting scheduled for May 3-7, 2024. The company aims to highlight the platform's potential in treating immunology-based diseases in addition to its primary focus on oncology. This marks an important step for Werewolf as it seeks to validate its approach and engage with experts in the immunology field. The specific poster presentation will focus on conditionally active IL-10 INDUKINE molecules for inflammatory bowel disease.

Read more →
HOWL
Mar 7, 2024
HOWLPhases

Werewolf Therapeutics Reports Fourth Quarter and Full Year 2023 Financial Results and Provides Business Update - Additional monotherapy dose-escalation data from ongoing Phase 1 1b clinical trial of WTX-124 expected to b

Werewolf Therapeutics reported its financial results for Q4 and full year 2023, highlighting significant advancements in its clinical pipeline. The company anticipates presenting additional data from its WTX-124 clinical trials in the first half of 2024 and expects to initiate dose expansion arms. Financial updates reveal a strong cash position, sufficient to support operations through at least Q2 2025, despite a decrease in collaboration revenue. The recent retirement of a key executive may also impact the company moving forward.

Read more →
HOWL
Mar 6, 2024
HOWLConferences/Events

Werewolf Therapeutics to Present at the 2024 Leerink Partners Global Biopharma Conference

Werewolf Therapeutics, a biopharmaceutical company focused on developing immune-stimulating therapeutics for cancer, announced their participation in the 2024 Leerink Partners Global Biopharma Conference. Daniel J. Hicklin, Ph.D., and Randi Isaacs, M.D. will represent the company in a fireside chat on March 13, 2024. The conference is set to take place in Miami, Florida, from March 11-13, 2024. Werewolf is known for its proprietary PREDATOR platform and is progressing with product candidates like WTX-124 and WTX-330.

Read more →
HOWL
Mar 5, 2024
HOWLConferences/Events

Werewolf Therapeutics Announces Upcoming Presentations at AACR Annual Meeting 2024

Werewolf Therapeutics has announced that it will present abstracts at the AACR Annual Meeting 2024, focused on innovative cancer therapies. The abstracts include data on WTX-712, an IL-21 INDUKINE molecule that induces a strong anti-tumor response, and WTX-518, an IL-18 pro-drug activated within tumor microenvironments. These presentations will take place on April 9, 2024, in San Diego, California, demonstrating the company's ongoing commitment to advancing cancer treatment through conditionally activated therapeutics.

Read more →
HOWL
Jan 8, 2024
HOWLPhases

Werewolf Therapeutics Provides Business Update and Highlights 2024 Strategic Outlook - Prioritizing development of wholly owned clinical assets, WTX-124 and WTX-330; key updates from both INDUKINE TM programs anticipated

Werewolf Therapeutics provided a strategic business update, emphasizing the development of their clinical assets, WTX-124 and WTX-330, for the upcoming year. The company anticipates releasing updated interim monotherapy data from WTX-124 in the first half of 2024 and dose-escalation data from WTX-330 in the second quarter of 2024. Additionally, Werewolf's financial outlook indicates sufficient cash to fund operations through at least the first quarter of 2025. The firm plans to explore partnerships to extend its innovative therapeutic approach beyond oncology.

Read more →
HOWL
Jan 4, 2024
HOWLGeneral

Werewolf Therapeutics Appoints Michael Atkins, M.D., to its Board of Directors

Werewolf Therapeutics has appointed Dr. Michael B. Atkins to its Board of Directors. Dr. Atkins is a distinguished oncologist with a wealth of experience in cancer immunotherapy research. His role is expected to provide invaluable insights as the company develops its INDUKINE therapeutics, WTX-124 and WTX-330. His background includes significant contributions to melanoma and kidney cancer research, positioning the company for strategic growth in innovative cancer therapies.

Read more →
HOWL
Nov 22, 2023
HOWLConferences/Events

Werewolf Therapeutics to Present at the Evercore ISI HealthCONx Conference

Werewolf Therapeutics, Inc. has announced that its President and CEO, Daniel J. Hicklin, and Chief Medical Officer, Randi Isaacs, will present at the Evercore ISI HealthCONx Conference in Miami, Florida, on November 29, 2023. The company is recognized for pioneering therapeutics that activate the immune system for cancer treatment, utilizing its proprietary PREDATOR™ platform to improve therapeutic outcomes. Their key product candidates, WTX-124 and WTX-330, target solid tumors and aim to enhance the efficacy of conventional therapies. A live webcast of the presentation will be made available for investors and interested parties.

Read more →
HOWL
Nov 14, 2023
HOWLPhases

Werewolf Therapeutics Reports Third Quarter 2023 Financial Results and Provides Business Update - Preliminary data from the WTX-124 monotherapy dose-escalation arm of the ongoing Phase 1 1b clinical trial provide compell

Werewolf Therapeutics reported its third-quarter financial results alongside a business update, highlighting promising preliminary data from the WTX-124 clinical trial. The data suggests WTX-124 has a favorable safety profile and shows early signs of anti-tumor activity in patients. Additionally, the company announced the introduction of WTX-518, a new therapeutic candidate aimed at enhancing immune responses. More data and recommended dose information for WTX-124 is expected in early 2024.

Read more →
HOWL
Nov 3, 2023
HOWLPhases

Werewolf Therapeutics Presents Preliminary Monotherapy Data from Phase 1/1b Clinical Trial Establishing Proof of Mechanism for WTX-124 at the Society for Immunotherapy of Cancer s (SITC) 38 th Annual Meeting - Preliminar

Werewolf Therapeutics presented preliminary data from its Phase 1/1b clinical trial for WTX-124 at the SITC 38th Annual Meeting. The results indicate dose-dependent biomarker and antitumor activity in patients with advanced or metastatic solid tumors. Notably, two patients showed ongoing unconfirmed partial responses at the highest dose tested. WTX-124 was well-tolerated, with no serious dose-limiting toxicities reported, supporting its potential as a differentiated IL-2 therapy. Further data from ongoing trials are anticipated in the first half of 2024.

Read more →
HOWL
Oct 31, 2023
HOWLConferences/Events

Werewolf Therapeutics to Present Clinical and Preclinical Data at the Society for Immunotherapy of Cancer’s (SITC) 38th Annual Meeting

Werewolf Therapeutics announced that it will present clinical and preclinical data at the Society for Immunotherapy of Cancer's 38th Annual Meeting. This includes interim results from the Phase 1/1b study of WTX-124, focusing on safety and preliminary antitumor activity. Additional data from the company's PREDATOR platform and INDUKINE product candidates will also be showcased. Werewolf's lead candidate, WTX-124, demonstrates promise in the treatment of solid tumors, with no dose-limiting toxicities reported thus far.

Read more →
HOWL
Sep 27, 2023
HOWLConferences/Events

Werewolf Therapeutics Announces Upcoming Presentations at the Society for Immunotherapy of Cancer’s (SITC) 38th Annual Meeting

Werewolf Therapeutics has announced the acceptance of six abstracts for poster presentations at the Society for Immunotherapy of Cancer’s 38th Annual Meeting, taking place from November 1-5, 2023. The company will present interim first-in-human clinical data from the ongoing Phase 1/1b study of WTX-124, an innovative treatment for cancer. The abstracts highlight advancements in their PREDATOR platform and INDUKINE pipeline, focusing on tumor-activated treatments designed to enhance the immune response against cancer. Werewolf's commitment to advancing cancer therapeutics is underscored by their participation in this significant event.

Read more →
HOWL
Sep 18, 2023
HOWLPhases

Cautionary Statements This presentation contains forward-looking statements that involve substantial risks and uncertainties. All statements, other than statements of historical facts, contained in this presentation, inc

Werewolf Therapeutics provided a corporate overview that includes forward-looking statements concerning its investigational drugs, WTX-124 and WTX-330, currently in Phase I clinical trials. Key focus areas include challenges with cytokine therapy, particularly around off-target toxicity, and the company's strategy to address these through advanced technology like the PREDATOR platform. The anticipated release of initial data for WTX-124 is expected in the fourth quarter of 2023, but there are significant risks associated with the development timelines, regulatory approvals, and financial stability.

Read more →
HOWL
Sep 11, 2023
HOWLConferences/Events

Werewolf Therapeutics to Host KOL Event Highlighting IL-2 Landscape and Opportunity for WTX-124

Werewolf Therapeutics is set to host a key opinion leader (KOL) event on September 18, 2023, featuring Dr. Michael Atkins discussing the IL-2 landscape. The company will present insights on its PREDATOR™ platform and the ongoing trials for its IL-2 targeted molecule, WTX-124. This candidate is being evaluated as both a monotherapy and in combination with Pembrolizumab for patients with advanced solid tumors who have not responded to standard therapies. The event underscores Werewolf's commitment to advancing innovative cancer treatments and engaging with the scientific community.

Read more →
HOWL
Aug 10, 2023
HOWLPhases

Werewolf Therapeutics Reports Second Quarter 2023 Financial Results and Provides Business Update - Phase 1 1b clinical trial for IL-2 INDUKINE WTX-124 progressing in patients with advanced or metastatic solid tumors init

Werewolf Therapeutics reported its second quarter financial results, highlighting progress in its clinical trials for WTX-124 and WTX-330, both targeting advanced solid tumors. The company anticipates sharing important initial data from the WTX-124 trial in Q4 2023. Financially, Werewolf maintains a strong cash position, expected to last through at least the end of 2024, and reported an increase in collaboration revenue. However, the company still recorded a net loss, albeit a smaller one than the previous year.

Read more →
HOWL
Jun 1, 2023
HOWLConferences/Events

Werewolf Therapeutics to Present at the Jefferies Healthcare Conference

Werewolf Therapeutics, an innovative biopharmaceutical company, announced that management will present an overview of the company at the Jefferies Healthcare Conference on June 8, 2023. The event will take place in New York, NY, and a live webcast will be available for interested parties. The company focuses on developing conditionally activated therapeutics that aim to enhance the immune system's ability to treat cancer. Their advanced product candidates include WTX-124 and WTX-330, aimed at solid tumors and designed to selectively activate in the tumor microenvironment.

Read more →
HOWL
May 11, 2023
HOWLPhases

Werewolf Therapeutics Reports First Quarter 2023 Financial Results and Provides Business Update - Progressing Phase 1 1b clinical trial for IL-2 INDUKINE WTX-124 in advanced or metastatic solid tumors initial first-in-hu

Werewolf Therapeutics reported its Q1 2023 financial results and provided a business update, highlighting progress in its clinical trials for the IL-2 INDUKINE WTX-124 and the IL-12 INDUKINE WTX-330 candidates. The company also revealed promising early preclinical data for a third candidate, WTX-712. Financially, Werewolf's cash position improved, providing a runway for its operations through at least Q4 2024, despite a reported net loss. These developments reflect the company's ongoing commitment to advancing innovative therapies for cancer treatment.

Read more →
HOWL
May 1, 2023
HOWLConferences/Events

Werewolf Therapeutics to Participate in May Investor Conferences

Werewolf Therapeutics, Inc. announced its participation in two key investor conferences in May 2023, including the Bank of America 2023 Healthcare Conference and the RBC Capital Markets Global Healthcare Conference. Management will engage in fireside chats to discuss the company's innovative therapies designed to stimulate the immune system for cancer treatment. The company leverages its proprietary PREDATOR™ platform to develop conditionally activated therapeutics aimed at improving outcomes for solid tumors. This participation is expected to bolster investor interest and enhance its market presence.

Read more →
HOWL
Apr 19, 2023
HOWLPhases

Werewolf Therapeutics Publishes Preclinical Data on mWTX-330, an IL-12 INDUKINE™ Molecule, in Cancer Immunology Research

Werewolf Therapeutics has published preclinical data for its mWTX-330 molecule, demonstrating its ability to selectively deliver Interleukin-12 to the tumor microenvironment, inducing a strong anti-tumor immune response. The data highlights the molecule's capacity to activate and enhance tumor-infiltrating lymphocytes while minimizing toxicity associated with traditional IL-12 therapies. The company is currently recruiting patients for a Phase 1 clinical trial, further validating the potential of this innovative therapy in cancer treatment. This preclinical research signifies a promising advancement in the field of cancer immunotherapy.

Read more →
HOWL
Mar 23, 2023
HOWLPhases

Werewolf Therapeutics Reports Fourth Quarter and Full Year 2022 Financial Results and Provides Business Update -Initial first-in-human clinical data for IL-2 INDUKINE WTX-124 monotherapy expected in 4Q 2023 from Phase 1

Werewolf Therapeutics reported its financial results for Q4 and full year 2022, highlighting significant progress in its clinical trials. The company provided updates on its lead candidates, WTX-124 and WTX-330, both of which are advancing towards initial clinical data expected in the fourth quarter of 2023. They also announced an extended cash runway through at least Q4 2024, ensuring funding for future operations. Overall, the company is demonstrating a positive trajectory in its oncology-focused therapeutic work.

Read more →
HOWL
Mar 15, 2023
HOWLConferences/Events

Werewolf Therapeutics Announces Upcoming Presentation at AACR Annual Meeting 2023

Werewolf Therapeutics, Inc. announced a forthcoming presentation at the AACR Annual Meeting 2023, scheduled for April 14-19 in Orlando, Florida. The presentation will feature an abstract on their IL-21 INDUKINE™ molecules, which are engineered to target cancer by stimulating the immune system. The company aims to address the limitations of traditional immune therapies with their proprietary PREDATOR™ platform and has advanced candidates WTX-124 and WTX-330 into clinical stages for various tumor types.

Read more →
HOWL
Feb 24, 2023
HOWLPhases

Werewolf Therapeutics Announces Initiation of Patient Dosing in Phase 1 Study of WTX-330

Werewolf Therapeutics has announced that the first patient has been dosed in its Phase 1 clinical trial for WTX-330, a novel IL-12 therapy targeting advanced solid tumors and Non-Hodgkin Lymphoma. This trial marks the second INDUKINE molecule from Waswolf’s development pipeline. The design of WTX-330 aims to enhance treatment efficacy while reducing toxic side effects commonly seen with traditional IL-12 therapies. The company is enthusiastic about the potential of this therapy to offer new options for patients facing hard-to-treat cancers.

Read more →
HOWL
Feb 7, 2023
HOWLConferences/Events

Werewolf Therapeutics to Present at the SVB Securities Global Biopharma Conference

Werewolf Therapeutics, Inc. will present virtually at the SVB Securities Global Biopharma Conference on February 16, 2023. Dr. Randi Isaacs, the Chief Medical Officer, will discuss the company's development of innovative cancer therapeutics using their unique PREDATOR™ platform. Their leading candidates, WTX-124 and WTX-330, aim to improve immune system responses selectively in tumors. A webcast of the presentation will be available live and archived for future viewing.

Read more →
HOWL
Nov 10, 2022
HOWLPhases

Werewolf Therapeutics Presents Preclinical Data on mWTX-330, a Surrogate IL-12 INDUKINE™ Molecule, at the Society for Immunotherapy of Cancer Annual Meeting

- mWTX-330 is designed as a systemically delivered, conditionally activated IL-12 therapy and is a member of a novel class of INDUKINE™ therapeutics - - Preclinical data supports the development of WTX-330, Werewolf’s product candidate, for the potential treatment of selected ad

Read more →
HOWL
Nov 10, 2022
HOWLPhases

Werewolf Therapeutics Reports Third Quarter 2022 Financial Results and Provides Business Update - Dosed first patient in Phase 1 1b study evaluating WTX-124 as a monotherapy and in combination with KEYTRUDA (pembrolizuma

Werewolf Therapeutics Reports Third Quarter 2022 Financial Results and Provides Business Update - Dosed first patient in Phase 1 1b study evaluating WTX-124 as a monotherapy and in combination with KEYTRUDA (pembrolizumab) in advanced solid tumors initial data anticipated in the

Read more →
HOWL
Nov 7, 2022
HOWLPhases

Werewolf Therapeutics to Present Preclinical Data at Society for Immunotherapy of Cancer Annual Meeting and Participate in Upcoming Investor Conferences

WATERTOWN, Mass., Nov. 07, 2022 (GLOBE NEWSWIRE) -- Werewolf Therapeutics, Inc. (the “Company” or “Werewolf”) (Nasdaq: HOWL), an innovative biopharmaceutical company pioneering the development of conditionally activated therapeutics engineered to stimulate the body’s immune syste

Read more →
HOWL
Sep 7, 2022
HOWLConferences/Events

Werewolf Therapeutics to Present at the H.C. Wainwright 24th Annual Global Investment Conference

WATERTOWN, Mass., Sept. 07, 2022 (GLOBE NEWSWIRE) -- Werewolf Therapeutics, Inc. (the “Company” or “Werewolf”) (Nasdaq: HOWL), an innovative biopharmaceutical company pioneering the development of conditionally activated therapeutics engineered to stimulate the body’s immune syst

Read more →
HOWL
Sep 1, 2022
HOWLPhases

Werewolf Therapeutics Announces Initiation of Patient Dosing in Phase 1/1b Clinical Trial of WTX-124 for the Treatment of Patients with Selected Solid Tumors

- First clinical candidate of a new class of systemically delivered conditionally activated INDUKINE™ therapeutics developed by Werewolf - WTX-124 is designed to target delivery of a highly potent, wild-type IL-2 cytokine to the tumor microenvironment WATERTOWN, Mass., Sept. 01

Read more →
HOWL
Aug 11, 2022
HOWLFDA Updates

Werewolf Therapeutics Reports Second Quarter 2022 Financial Results and Provides Business Highlights - FDA granted IND clearance for lead candidate WTX-124 for evaluation as a treatment for advanced solid tumors - - Subm

Werewolf Therapeutics Reports Second Quarter 2022 Financial Results and Provides Business Highlights - FDA granted IND clearance for lead candidate WTX-124 for evaluation as a treatment for advanced solid tumors - - Submission of IND application for WTX-330 planned in 2H22 - -

Read more →
HOWL
Aug 3, 2022
HOWLConferences/Events

Werewolf Therapeutics to Participate in the 2022 Wedbush PacGrow Healthcare Virtual Conference

WATERTOWN, Mass., Aug. 03, 2022 (GLOBE NEWSWIRE) -- Werewolf Therapeutics, Inc. (the “Company” or “Werewolf”) (Nasdaq: HOWL), an innovative biopharmaceutical company pioneering the development of conditionally activated therapeutics engineered to stimulate the body’s immune syste

Read more →
HOWL
Jun 6, 2022
HOWLConferences/Events

Werewolf Therapeutics to Participate in a Fireside Chat at the Jefferies Global Healthcare Conference

CAMBRIDGE, Mass., June 06, 2022 (GLOBE NEWSWIRE) -- Werewolf Therapeutics, Inc. (the “Company” or “Werewolf”) (Nasdaq: HOWL), an innovative biopharmaceutical company pioneering the development of conditionally activated therapeutics engineered to stimulate the body’s immune syste

Read more →
HOWL
May 10, 2022
HOWLGeneral

Werewolf Therapeutics Reports First Quarter 2022 Financial Results and Provides Business Highlights - Entered exclusive global license and collaboration agreement with Jazz Pharmaceuticals to develop and commercialize WT

Werewolf Therapeutics Reports First Quarter 2022 Financial Results and Provides Business Highlights - Entered exclusive global license and collaboration agreement with Jazz Pharmaceuticals to develop and commercialize WTX-613 received $15.0M upfront payment and eligibility for u

Read more →
HOWL
Apr 8, 2022
HOWLPhases

Werewolf Therapeutics Presents Promising Preclinical Data on its Two Lead INDUKINE™ Molecules at AACR 2022 Annual Meeting

WTX-124 demonstrated high tumor selectivity and generated significant anti-tumor activity in a CD8+ T cell-dependent manner WTX-330 surrogate demonstrated significant expansion of the therapeutic window, compared to recombinant IL-12, and generated potent anti-tumor immunity in

Read more →
HOWL
Mar 24, 2022
HOWLPhases

Werewolf Therapeutics Reports Fourth Quarter 2021 and Full Year 2021 Financial Results and Provides Business Highlights -Closed upsized IPO in May 2021 raising $120 million in gross proceeds- -Announced clinical trial co

Werewolf Therapeutics Reports Fourth Quarter 2021 and Full Year 2021 Financial Results and Provides Business Highlights -Closed upsized IPO in May 2021 raising $120 million in gross proceeds- -Announced clinical trial collaboration with Merck for WTX-124 INDUKINETM program- -R

Read more →
HOWL
Mar 16, 2022
HOWLGeneral

Werewolf Therapeutics Announces Publication of Data Demonstrating the Preclinical Efficacy of WTX-124 in Delivering IL-2 Selectively to the Tumor Microenvironment

CAMBRIDGE, Mass., March 16, 2022 (GLOBE NEWSWIRE) -- Werewolf Therapeutics, Inc. (the “Company” or “Werewolf”) (Nasdaq: HOWL), an innovative biopharmaceutical company pioneering the development of conditionally activated therapeutics, announced the publication in Cancer Immunolog

Read more →
HOWL
Mar 15, 2022
HOWLConferences/Events

Werewolf Therapeutics Announces Upcoming Presentations at AACR 2022 Annual Meeting

CAMBRIDGE, Mass., March 15, 2022 (GLOBE NEWSWIRE) -- Werewolf Therapeutics, Inc. (the “Company” or “Werewolf”) (Nasdaq: HOWL), an innovative biopharmaceutical company pioneering the development of conditionally activated therapeutics engineered to stimulate the body’s immune syst

Read more →
HOWL
Feb 8, 2022
HOWLConferences/Events

Werewolf Therapeutics to Present at the SVB Leerink Global Healthcare Conference

CAMBRIDGE, Mass., Feb. 08, 2022 (GLOBE NEWSWIRE) -- Werewolf Therapeutics, Inc. (the “Company” or “Werewolf”) (Nasdaq: HOWL), an innovative biopharmaceutical company pioneering the development of conditionally activated therapeutics engineered to stimulate the body’s immune syste

Read more →
HOWL
Jan 5, 2022
HOWLConferences/Events

Werewolf Therapeutics to Present at the H.C. Wainwright Bioconnect Conference

CAMBRIDGE, Mass., Jan. 05, 2022 (GLOBE NEWSWIRE) -- Werewolf Therapeutics, Inc. (the “Company” or “Werewolf”) (Nasdaq: HOWL), an innovative biopharmaceutical company pioneering the development of conditionally activated therapeutics engineered to stimulate the body’s immune syste

Read more →
HOWL
Dec 14, 2021
HOWLGeneral

Werewolf Therapeutics Added to the Nasdaq Biotechnology Index

CAMBRIDGE, Mass., Dec. 14, 2021 (GLOBE NEWSWIRE) -- Werewolf Therapeutics, Inc. (the “Company” or “Werewolf”) (Nasdaq: HOWL), an innovative biopharmaceutical company pioneering the development of conditionally activated therapeutics engineered to stimulate the body’s immune syste

Read more →
HOWL
Dec 1, 2021
HOWLPhases

Werewolf Therapeutics to Present Preclinical Data on INDUKINE™ Molecules at the 63rd American Society of Hematology (ASH) Annual Meeting

CAMBRIDGE, Mass., Dec. 01, 2021 (GLOBE NEWSWIRE) -- Werewolf Therapeutics, Inc. (the “Company” or “Werewolf”) (Nasdaq: HOWL), an innovative biopharmaceutical company pioneering the development of conditionally activated therapeutics engineered to stimulate the body’s immune syste

Read more →
HOWL
Nov 10, 2021
HOWLPhases

Werewolf Therapeutics Reports Third Quarter 2021 Financial Results and Business Update -Clinical Trial Collaboration with Merck for WTX-124 INDUKINE Program- -On Track to File Two INDs in First Half of 2022- Cambridge, M

Werewolf Therapeutics Reports Third Quarter 2021 Financial Results and Business Update -Clinical Trial Collaboration with Merck for WTX-124 INDUKINE Program- -On Track to File Two INDs in First Half of 2022- Cambridge, Mass., November 10, 2021 - Werewolf Therapeutics, Inc. (th

Read more →
HOWL
Nov 8, 2021
HOWLConferences/Events

Werewolf Therapeutics to Present at Upcoming Conferences in November 2021

CAMBRIDGE, Mass., Nov. 08, 2021 (GLOBE NEWSWIRE) -- Werewolf Therapeutics, Inc. (Nasdaq: HOWL), an innovative biopharmaceutical company pioneering the development of conditionally activated therapeutics engineered to stimulate the body’s immune system for the treatment of cancer,

Read more →
HOWL
Oct 28, 2021
HOWLGeneral

Werewolf Therapeutics Appoints Meeta Chatterjee, Ph.D., to its Board of Directors

CAMBRIDGE, Mass., Oct. 28, 2021 (GLOBE NEWSWIRE) -- Werewolf Therapeutics, Inc. (Nasdaq: HOWL), an innovative biopharmaceutical company pioneering the development of conditionally activated therapeutics engineered to stimulate the body’s immune system for the treatment of cancer,

Read more →
HOWL
Oct 27, 2021
HOWLConferences/Events

Werewolf Therapeutics to Present Data on its INDUKINE™ Product Candidates at the Society for Immunotherapy of Cancer Annual Meeting

CAMBRIDGE, Mass., Oct. 27, 2021 (GLOBE NEWSWIRE) -- Werewolf Therapeutics, Inc. (Nasdaq: HOWL), an innovative biopharmaceutical company pioneering the development of conditionally activated therapeutics engineered to stimulate the body’s immune system for the treatment of cancer,

Read more →
HOWL
Sep 14, 2021
HOWLConferences/Events

Werewolf Therapeutics to Present at Upcoming Next-Gen Cytokine Therapeutics Summit

CAMBRIDGE, Mass., Sept. 14, 2021 (GLOBE NEWSWIRE) -- Werewolf Therapeutics, Inc. (Nasdaq: HOWL), an innovative biopharmaceutical company pioneering the development of conditionally activated therapeutics engineered to stimulate the body’s immune system for the treatment of cancer

Read more →
HOWL
Sep 8, 2021
HOWLConferences/Events

Werewolf Therapeutics to Present at H. C. Wainwright Global Investment Conference

CAMBRIDGE, Mass., Sept. 08, 2021 (GLOBE NEWSWIRE) -- Werewolf Therapeutics, Inc. (Nasdaq: HOWL), an innovative biopharmaceutical company pioneering the development of conditionally activated therapeutics engineered to stimulate the body’s immune system for the treatment of cancer

Read more →
HOWL
Aug 18, 2021
HOWLPhases

Werewolf Therapeutics Announces Clinical Trial Collaboration with Merck on its WTX-124 INDUKINE™ Program

CAMBRIDGE, Mass., Aug. 18, 2021 (GLOBE NEWSWIRE) -- Werewolf Therapeutics, Inc. (Nasdaq: HOWL), an innovative biopharmaceutical company pioneering the development of conditionally activated therapeutics engineered to stimulate the body’s immune system for the treatment of cancer,

Read more →
HOWL
Aug 12, 2021
HOWLGeneral

Werewolf Therapeutics Reports Second Quarter 2021 Financial Results and Business Update Cambridge, Mass.

Werewolf Therapeutics Reports Second Quarter 2021 Financial Results and Business Update Cambridge, Mass., August 12, 2021 - Werewolf Therapeutics, Inc. (the "Company" or "Werewolf") (Nasdaq HOWL), an innovative biopharmaceutical company pioneering the development of conditionall

Read more →
HOWL
Jun 24, 2021
HOWLGeneral

Werewolf Therapeutics Announces Its Addition to the Russell 2000 Index

CAMBRIDGE, Mass., June 24, 2021 (GLOBE NEWSWIRE) -- Werewolf Therapeutics, Inc., an innovative biopharmaceutical company pioneering the development of conditionally activated therapeutics engineered to stimulate the body’s immune system for the treatment of cancer, today announce

Read more →
HOWL
Jun 15, 2021
HOWLGeneral

Werewolf Therapeutics Appoints Chulani Karunatilake, Ph.D. as Chief Technology Officer

Veteran life sciences executive brings more than 30 years CMC and product development strategy expertise to rapidly advance programs and oversee manufacturing CAMBRIDGE, Mass., June 15, 2021 (GLOBE NEWSWIRE) -- Werewolf Therapeutics, Inc. (NASDAQ: HOWL), an innovative biopharmac

Read more →
HOWL
Jun 10, 2021
HOWLGeneral

Werewolf Therapeutics Reports First Quarter 2021 Financial Results - Recently completed upsized initial public offering raising $120.0 million in gross proceeds - Cambridge, Mass.

Werewolf Therapeutics Reports First Quarter 2021 Financial Results - Recently completed upsized initial public offering raising $120.0 million in gross proceeds - Cambridge, Mass., June 10, 2021 - Werewolf Therapeutics, Inc. (the "Company" or "Werewolf") (NASDAQ HOWL), an innov

Read more →
HOWL
May 27, 2021
HOWLConferences/Events

Werewolf Therapeutics to Present at Jefferies Virtual Healthcare Conference 2021

CAMBRIDGE, Mass., May 27, 2021 (GLOBE NEWSWIRE) -- Werewolf Therapeutics, Inc. (Nasdaq: HOWL), an innovative biopharmaceutical company pioneering the development of conditionally activated therapeutics engineered to stimulate the body’s immune system for the treatment of cancer,

Read more →
HOWL
Apr 30, 2021
HOWLGeneral

Werewolf Therapeutics Announces Pricing of Upsized Initial Public Offering

CAMBRIDGE, Mass., April 29, 2021 (GLOBE NEWSWIRE) -- Werewolf Therapeutics, Inc. (NASDAQ: HOWL), an innovative biopharmaceutical company pioneering the development of conditionally activated therapeutics engineered to stimulate the body’s immune system for the treatment of cancer

Read more →
Competitive Position
How HOWL ranks across every disease it competes in
Competitive Position is a premium feature
See how HOWL ranks against every competitor across each disease it develops in: phase, best drug, trials and likelihood of approval.
Start free trial