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Travoprost

Phase 2

Open Angle Glaucoma | Small molecule | Ophthalmology |Glaukos Corporation|Last Updated: Sep 26, 2023

Success Probability
Approval Probability 71%
TA Base Rate26%
Adjusted LOA41%
ML RiskLOW_RISK
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Market & Valuation
rNPV $3.2B
Market Size $9.4B
Revenue Basis $1.6B
Competitors 6
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Trial Design
UNCONTROLLED
Total Trials1
Total Enrollment33
FDA Designations
No designations recorded
Clinical Trials (1)
NCT IDTitlePhaseStatusEnrollmentVelocityDesignStartCompletionLast UpdatedSitesCountries
NCT04615403Study of Exchange of Travoprost Intraocular ImplantPHASE2 COMPLETED 33Nov 19, 2020Feb 28, 2022Sep 26, 202314 United States, Philippines
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Study Endpoints
Primary Endpoints
Ocular Safety
12 Months

Number of subjects with Adverse Events including intra-operative and post-operative events (TEAE's) in the study eye

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Study Design & Arms
AllocationNA
MaskingNONE
ModelSINGLE_GROUP
PurposeTREATMENT
Treatment Arms
ArmTypeDescription
Implantation and ExchangeEXPERIMENTALSubjects will undergo implantation and exchange of a Travoprost Intraocular Implant through a small temporal clear corneal incision.
Interventions
NameTypeDescription
TravoprostDRUGImplantation and exchange of a Travoprost Intraocular Implant through a clear corneal incision
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Eligibility Criteria
Age Range18 Years — N/A
SexALL
Healthy VolunteersNo
Study Sites14

Inclusion Criteria: * Able and willing to attend scheduled follow-up exams for the duration of the study * Able and willing to provide written informed consent on the IRB (institutional review board)/IEC (institutional ethics committee)-approved Informed Consent form * Best spectacle corrected visu...

Countries:United StatesPhilippines
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Competitive Landscape -Open-Angle Glaucoma 9 trials