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Bimatoprost 0.03% sterile

Phase 3

Eyelashes | Small molecule | Other |AbbVie Inc.|Trials Updated: Oct 30, 2013

Bimatoprost 0.03% sterile target and mechanism

Molecular targetPTGFR
Target classAgonist
ModalitySmall molecule

Also known as Bimatoprost 0.03% sterile solution

Success Probability

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Market & Valuation

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Trial Design

RandomizedDouble-BlindPLACEBO_CONTROLLED
Total Trials1
Total Enrollment278

FDA Designations

No designations recorded

Bimatoprost 0.03% sterile clinical trials

Bimatoprost 0.03% sterile · 1 trial · 1 indication

Phase 3 1
NCT00693420Safety and Efficacy of Bimatoprost Solution in Increasing Overall Eyelash ProminenceEyelashes
COMPLETED278 Analytics
PHASE3COMPLETED
Safety and Efficacy of Bimatoprost Solution in Increasing Overall Eyelash Prominence
EyelashesUnlock trial analytics

Study Endpoints

Primary Endpoints

Percentage of Participants Experiencing at Least a 1-grade Increase on the Global Eyelash Assessment (GEA) Scale From Baseline to Week 16
Baseline to Week 16

The GEA scale is an investigator-graded 4-point ordinal scale of overall eyelash prominence (1 \[minimal\], 2 \[moderate\], 3 \[marked\], 4 \[very marked\])

Percentage of Participants Experiencing at Least a 1-grade Increase on the Global Eyelash Assessment (GEA) Scale From Baseline to Week 20 (Post-treatment)
Baseline to Week 20

The GEA scale is an investigator-graded 4-point ordinal scale of overall eyelash prominence (1 \[minimal\], 2 \[moderate\], 3 \[marked\], 4 \[very marked\])

Secondary Endpoints

Upper Eyelash Length as Measured by Digital Image Analysis in Terms of Change From Baseline to Week 16
Baseline to Week 16
Upper Eyelash Length as Measured by Digital Image Analysis in Terms of Change From Baseline to Week 20 (Post-treatment)
Baseline to Week 20
Upper Eyelash Thickness as Measured by Digital Image Analysis in Terms of Change From Baseline to Week 16
Baseline to Week 16
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Study Design & Arms

AllocationRANDOMIZED
MaskingDOUBLE
ModelPARALLEL
PurposeTREATMENT

Treatment Arms

ArmTypeDescription
1EXPERIMENTALBimatoprost 0.03% solution
2PLACEBO_COMPARATORVehicle solution

Interventions

NameTypeDescription
Bimatoprost 0.03% sterile solutionDRUGApply one drop of study medication using single-use per eye applicator to upper eyelid margin once daily.
vehicle sterile solutionDRUGApply one drop of study medication using single-use per eye applicator to upper eyelid margin once daily
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Eligibility Criteria

Age Range18 Years to N/A
SexALL
Healthy VolunteersYes
Study Sites2

Inclusion Criteria: * Dissatisfaction with eyelash prominence, * Eyelash prominence assessment of minimal or moderate, * Ability to provide written informed consent Exclusion Criteria: * Subjects without visible lashes, * Asymmetrical (uneven lashes or longer on one side than the other) eyelashes...

Countries:United StatesCanada
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Frequently asked questions about Bimatoprost 0.03% sterile

What is Bimatoprost 0.03% sterile used for?

Bimatoprost 0.03% sterile is used to increase overall eyelash prominence. It is a small molecule developed by AbbVie Inc. (ticker ABBV) and studied in adults aged 18 years and older. The Phase 3 program enrolled 278 participants in the United States and Canada.

What does Bimatoprost 0.03% sterile target?

Bimatoprost 0.03% sterile targets PTGFR, the prostaglandin F receptor, where it acts as an agonist. This receptor activity underlies its intended effect on eyelash prominence in the studied indication.

Who makes Bimatoprost 0.03% sterile?

Bimatoprost 0.03% sterile is developed by AbbVie Inc., which trades under the ticker ABBV. AbbVie is the company associated with the Phase 3 development program for this eyelash indication.

What phase is Bimatoprost 0.03% sterile in?

Bimatoprost 0.03% sterile is in Phase 3 development. It is an investigational small molecule and is not described as approved. The Phase 3 trial has completed, and no trials are currently listed as active.

What clinical trials is Bimatoprost 0.03% sterile in?

Bimatoprost 0.03% sterile was studied in the Phase 3 trial NCT00693420, titled Safety and Efficacy of Bimatoprost Solution in Increasing Overall Eyelash Prominence. That trial is completed, was randomized, double blind, and placebo controlled, and enrolled 278 participants across the United States and Canada.

Is Bimatoprost 0.03% sterile the same as Bimatoprost 0.03% sterile solution?

Yes. Bimatoprost 0.03% sterile and Bimatoprost 0.03% sterile solution refer to the same product. The alternative name describes the same sterile solution formulation of bimatoprost at 0.03% strength.