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Hemab Therapeutics Holdings, Inc.

$29.97

-1.03 (-3.32%)

D 37Pipeline Score Overvalued Biotech · Clinical
Market Cap
1.21 B
EPS
-
P/E Ratio
-
Value Trade
5.61 M
SEC Financials
Q1 2026
  • Dilution Risk

    15%
  • R&D Expenses

    19.46 M

  • Operating CF

    -21.58 M


  • Total Assets

    175.26 M

  • Total Liabilities

    13.71 M

  • Equity

    -198.62 M

  • D/E Ratio

    12,345

-8.71 %
Week
-16.13 %
1 Month
-16.13 %
3 Month
-16.13 %
6 Month
-16.13 %
5 Year
-16.13 %
All Time
Cash Data
Stable
  • Cash Position

    163.53 M

  • Monthly Burn

    7.20 M

  • Runway

    21.3 mo

  • Burn Trend

    Accelerating
  • SEC Filing

    May 21, 2026
Overview
Volume
618.12 K
52 Week Range
23.00 - 32
% held by Insiders
28.79 %
% held by Institutions
32.9 %
Enterprise Value
1.41 B
Total Shares
39.25 M
Short %
4.07 %
Float Shares
15.97 M
Company Description
HQ: 101 MAIN STREET, CAMBRIDGE, MA...
Founded:2020

locked

Upcoming Catalyst
Catalyst Drug/Treatment Stage Probability of Approval Description Drug Type Therapeutic Area Source
HMB-003 Heavy menstrual bleeding
Pre-clinical

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Small Molecules
Reproductive System
HMB-003 Heavy menstrual bleeding
Pre-clinical

Subscribe to access the data.

Small Molecules
Reproductive System
HMB-003 Heavy menstrual bleeding
Pre-clinical

Subscribe to access the data.

Small Molecules
Reproductive System
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Catalyst Timeline

Dated clinical, regulatory & corporate events for Hemab Therapeutics Holdings, Inc.

12Total events
8Upcoming
2Tier-1 (high impact)
2026 – 2027Coverage

Upcoming catalysts 8

Jul 11, 2026
T2Oral Presentation
HMB-003, a long-acting peptide plasmin inhibitor, potently inhibits fibrinolysis and localizes with fibrin in a human whole blood microfluidic flow model
HMB-003Bleeding disordersPreclinical
Jul 12, 2026
T2Oral Presentation
Elucidating Sutacimig’s Dual Mechanism in Factor VII Deficiency
SutacimigFactor VII deficiencyPhase 2
Jul 12, 2026
T2Oral Presentation
First-in-human investigation of HMB-002: a subcutaneous antibody for prophylactic management of Von Willebrand disease
HMB-002Von Willebrand diseasePhase 1/2
Jul 12, 2026
T3Poster Presentation
Optimization of the Halo Fluorescence Fibrinolysis Assay: How Plasma Overlay and Timing Influence Antifibrinolytic Assessment
HMB-003Bleeding disordersPreclinical
Jul 14, 2026
T2Oral Presentation
Sutacimig Prophylaxis in Glanzmann Thrombasthenia: Results from a Phase 2 Long-Term Extension
SutacimigGlanzmann thrombastheniaPhase 2
Jul 14, 2026
T3Poster Presentation
Substantial Bleeding Burden and Limited Prophylaxis Use in Glanzmann Thrombasthenia: Prospective Real-World Data from ATHN Transcends
SutacimigGlanzmann thrombastheniaPhase 2
Dec 2026
T1Topline Readout
Data expected from Phase 2 proof-of-concept study in FVIID
SutacimigFactor VII deficiencyPhase 2
2027
T2Trial Initiation
Studies in heavy menstrual bleeding planned for HMB-003
HMB-003Heavy menstrual bleedingPhase 1

Event history 4

Q3 2026
Trial InitiationSutacimigTrial
Phase 3 initiation planned for sutacimig in GT
Glanzmann thrombastheniasource ↗
Q3 2026
Trial InitiationHMB-003Trial
First-in-human studies for HMB-003 planned
Bleeding disorderssource ↗
TBD
Breakthrough Therapy DesignationSutacimigDesignation
FDA Breakthrough Therapy Designation for sutacimig in GT
Glanzmann thrombastheniasource ↗
TBD
EMA PrimeSutacimigEx-US Regulatory
EMA PRIME designation for sutacimig in GT
Glanzmann thrombastheniasource ↗
Drug Pipeline Intelligence
D37
Pipeline Score
$245M
Pipeline Value
Overvalued
Valuation Signal
3
Drugs Scored
0.2x
rNPV / MCap
Top 51%
Micro Cap
(rank 445 of 906)
Percentile Rank
Hemab Therapeutics Holdings, Inc. faces pipeline headwinds (37/100), with $738M risk-adjusted pipeline value, led by Sutacimig in Congenital Factor VII Deficiency (Phase 2).
Showing 1 of 1 assets
DrugIndicationPhaseNCT IDPTRSrNPVStatusEnrollmentVelocityDesignCompletionML SignalLast Change
Sutacimig
Small molecule
Congenital Factor VII DeficiencyPhase 2NCT0734724960% $657M RECRUITING 18 AVERAGE D (29) Jul 1, 2026 -LOW
May 29, 2026
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Clinical Trial Results
Drug Name Indications Phase Date Trial Results Summary Title Source
HMB-002
Von Willebrand disease
2026-06-26

elevating Von Willebrand Factor (VWF) and Factor VIII (FVIII) levels

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Hemab Therapeutics to Present Clinical and Preclinical Data from Multiple Blood Coagulation Programs at the ISTH 2026 Congress

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HMB-002
Von Willebrand disease
2026-06-26

elevating Von Willebrand Factor (VWF) and Factor VIII (FVIII) levels

Read More

Hemab Therapeutics to Present Clinical and Preclinical Data from Multiple Blood Coagulation Programs at the ISTH 2026 Congress

Read More
HMB-002
Von Willebrand disease
2026-06-26

elevating Von Willebrand Factor (VWF) and Factor VIII (FVIII) levels

Read More

Hemab Therapeutics to Present Clinical and Preclinical Data from Multiple Blood Coagulation Programs at the ISTH 2026 Congress

Read More
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Inside Trades
TREND
CORPORATE INSIDERS BOUGHT SHARES WORTH 1.8M IN THE LAST 3 MONTHS
YEARLY INSIDER TRANSACTIONS
Sector Avg.
INSIDERS
SOLD
INSIDERS
BOUGHT
POSITIVE SENTIMENT Based on 22 Insiders Transactions
Unlock Inside Trades data
Hedge Funds
TREND
HEDGE FUNDS INCREASED HOLDINGS BY 200.0K SHARES IN THE LAST QUARTER
Shares Held
2040.00B1530.00B1020.00B510.00B0
Q3
2024
Q4
2024
Q1
2025
Q2
2025
HEDGE FUNDS
SOLD
HEDGE FUNDS
BOUGHT
POSITIVE SENTIMENT Based on 27 hedge funds in the last quarter
18 buying (3 new)·9 selling (1 exited)·2 unchanged
Fund Count
60%
Share Volume
25%
Conviction
15%
HedgeFund Name
( 3 )
% of Portfolio Current MV
-
Shares Owned
-
Activity
Avg Price $0

Example Capital Management

2.5 %
15.00 M
250.00 K

Example Capital Management

2.5 %
15.00 M
250.00 K

Example Capital Management

2.5 %
15.00 M
250.00 K
Unlock Hedge Funds table data
COAG Institutional Ownership Trends
Current Insider %
5.20%
+0.00%
Current Institutional %
62.40%
+0.00%
Total Ownership
67.60%
Insider + Institutional
Data Points
1
1 Ticker(s)
Option Chain Statistics
ExpirationVolumeOpen InterestImplied Volatility CallsImplied Volatility Puts
CallsPutsPut-Call RatioCallsPutsPut-Call RatioIVOiWaIvVWaIvIVOiWaIvVWaIv
Unlock Option Chain Statistics data
Option Chain
CallsStrikePuts
Last PriceVolumeOpen InterestLast PriceVolumeOpen Interest
No data available
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Open interest
0 600K 1.2M 1.8M Avg OI 1.00 M Open Interest
0 1 2 3 1.1 Put-Call Ratio
Today's Open Interest
1.00 M
Put-Call Ratio
1.1
Put Open Interest
480.00 K
Call Open Interest
520.00 K
Open Interest Avg (30-day)
900,000
Today vs Open Interest Avg (30-day)
11.11%
Option Volume
0 450K 900K 1.4M Avg OV 750.00 K Option Volume
0 1 2 3 0.95 Put-Call Ratio
Today's Volume
750.00 K
Put-Call Ratio
0.95
Put Volume
360.00 K
Call Volume
390.00 K
Volume Avg (30-day)
800,000
Today vs Volume Avg (30-day)
-6.25%
Company News
COAG
Jun 26, 2026
COAGConferences/Events

Hemab Therapeutics to Present Clinical and Preclinical Data from Multiple Blood Coagulation Programs at the ISTH 2026 Congress

Hemab Therapeutics announced significant advancements in its blood coagulation programs, including promising first-in-human data for HMB-002 in Von Willebrand disease and the introduction of HMB-003, a new peptide plasmin inhibitor. The company plans to present nine studies at the ISTH 2026 Congress, showcasing its commitment to addressing critical gaps in coagulation disorder treatments. Sutacimig has also received FDA Breakthrough Therapy designation, with a Phase 3 trial expected to begin in the second half of 2026.

Read more →
COAG
May 27, 2026
COAGConferences/Events

Hemab Therapeutics to Participate in the 2026 Jefferies Global Healthcare Conference

Hemab Therapeutics will participate in the 2026 Jefferies Global Healthcare Conference, where its management team will present and hold investor meetings. The event is scheduled for June 4, 2026, in New York, NY. Hemab is focused on developing therapies for blood coagulation disorders, including treatments for Glanzmann thrombasthenia and Von Willebrand Disease.

Read more →
COAG
May 21, 2026
COAGGeneral

Hemab Therapeutics Reports First Quarter 2026 Financial Results Completed Initial Public Offering in May 2026, raising gross proceeds of $346.7 million and listing on Nasdaq Granted Breakthrough Therapy Designation for s

Hemab Therapeutics has reported its first quarter financial results for 2026, highlighting the successful completion of an initial public offering that raised $346.7 million and secured a listing on Nasdaq. The company received Breakthrough Therapy Designation for sutacimig, a bispecific antibody for Glanzmann thrombasthenia. Despite these advancements, Hemab reported a net loss of $22.687 million in the quarter, with a decrease in cash reserves compared to the previous quarter.

Read more →
COAG
May 1, 2026
COAGGeneral

Hemab Therapeutics Announces Pricing of Upsized Initial Public Offering

Hemab Therapeutics Holdings, Inc. has announced the pricing of its initial public offering, offering 16,750,000 shares at $18.00 each. The IPO is expected to generate around $301.5 million in gross proceeds. Trading is set to begin on the Nasdaq Global Select Market under the ticker 'COAG' on May 1, 2026, with the offering closing around May 4, 2026.

Read more →
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