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CNS Pharmaceuticals, Inc.

CNSP
Richly ValuedPharma · Clinical
FDA catalysts, PDUFA dates & pipeline intelligence
$5.35
▲ 0 · 0%

Financials

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52W LOW $1.9052W HIGH $10.54
Volume
1.16 K
Value Traded
7.08 K
Short % Float
0.21%
+0.94%Week
-6.96%1 Month
+5.11%3 Month
+113.15%6 Month
-100%5 Year
-100%All Time

Cash Data

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  • Monthly Burn
  • Burn Trend
  • Dilution Risk
  • SEC Filing

Key Stats

Market Cap
7.82 M
EPS (TTM)
-11.43
P/E Ratio
-
Ent. Value
-12.17 M
Total Shares
1.46 M
Float Shares
1.44 M
Insiders
1.44%
Institutions
19.19%

Upcoming Catalysts

FDA decisions, readouts and PDUFA dates · scored by probability of approval

Catalyst Drug / Treatment Stage Prob. of Approval Description Drug Type Therapeutic Area Source
PDUFA
2026
Example Drug
Treatment for example condition requiring FDA review
Phase 3Small MoleculeOncology-
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Every FDA decision, readout and PDUFA date, with drug type, therapeutic area and a PoA score you can trade on.
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PoA blends historical approval base rates, trial design score and FDA review track record.

CNSP Catalyst Timeline

Dated clinical, regulatory and corporate events for CNS Pharmaceuticals, Inc.

Catalyst Timeline

Dated clinical, regulatory & corporate events for CNS Pharmaceuticals, Inc.

161Total events
4Upcoming
28Tier-1 (high impact)
2019 to 2026Coverage

Upcoming catalysts 2

T1Partnership / License
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T2Runway Guidance Update
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Event history 50

●Trial CompletionBerubicinFiledTrial
Global clinical trial of Berubicin for glioblastoma is complete
glioblastomasource ↗
●Quarterly UpdateCorporate
Reported Q2 2026 financial results
▲Equity OfferingCorporate
Closed oversubscribed $22.5 million private placement
●Management ChangeCorporate
Appointed Michal Fisher to Board of Directors
▲Management ChangeCorporate
Appointment of Lynne Kelley, MD, FACS, as Chief Medical Officer
▼Reverse Stock SplitCorporate
1-for-12 reverse stock split of common stock
▼Topline ReadoutBerubicinFiledClinical Data
Reported Primary Analysis of Berubicin Monotherapy in 2nd line GBM
Glioblastoma Multiforme (GBM)source ↗
▼Topline ReadoutBerubicinFiledClinical Data
Reported Primary Analysis of Berubicin Monotherapy in 2nd line GBM
Glioblastoma Multiforme (GBM)source ↗
▼Reverse Stock SplitCorporate
1-for-50 reverse stock split effective February 21, 2025
◆Timing GuidancePresentation
Plan to engage with regulators to design potential registration study in 2025
Glioblastoma Multiforme (GBM)source ↗
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Every PDUFA date, readout, approval and corporate move, tiered by market impact and updated daily.
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Past FDA Catalysts and PDUFA Decisions

How CNSP actually traded into and out of each decision

Date Drug Catalyst Stage Reaction Event Move % Best Trade %
2025-06-30Berubicin Phase 2 topline data readout Phase 2
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Reaction: 30 trading days around the event · Event Move: close to close on decision day · Best Trade: peak run-up from entry 10 days before the decision

Drug Pipeline Intelligence

D28 / 100
Pipeline Score
$1M
Pipeline Value
Richly Valued
Valuation Signal
1
Drugs Scored
0.2x
rNPV / MCap
Top 74%
Micro Cap
(rank 489 of 660)
Percentile Rank
CNS Pharmaceuticals, Inc. faces pipeline headwinds (28/100), with $91M risk-adjusted pipeline value, led by Berubicin in Glioblastoma Multiforme, Adult (Phase 2).
Showing 1 of 1 assets
DrugIndicationPhasePTRSrNPVStatusEnrollVelocityDesignEst. CompletionML SignalLast Change
Berubicin Small moleculeNCT04762069Glioblastoma Multiforme, AdultPhase 2 ACTIVE NOT_RECRUITING 252Jul 15, 2026
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Clinical Trial Results

Readouts, endpoints and source filings for every CNSP program

Drug Name Indication Phase Date Trial Results SummaryTitleSource
Berubicin
Fast TrackOrphan
Glioblastoma Multiforme2025-07-15Did not a statistically significant difference in overall survivalRead MoreNASDAQ: CNSP July 2025 2 Forward Looking Statements This presentation incorporates information from materials filed with the SEC and contains forward - looking statements. All statements contained herein other than stateRead More
Scroll for more · summaries link to the source press release
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Inside Trades

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Monthly insider buys and sells against the stock price, with the insider sentiment reading.
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InsiderSideSharesPriceValueDate
Levin RamiOfficer (CEO and President)Option -4,750 14,250 held$0.00 08/14/2026
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Hedge Fund 13F Activity

Fund % of Portfolio Current MV Shares Owned Activity
Ikarian Capital, LLC 0 % 109.00 K 45.83 K
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Shares held by hedge funds each quarter, and who bought or sold.

CNSP Institutional Ownership Trends

Options Data

Option Volume

Open Interest
Call OI
Put OI
Put-Call Ratio
OI 30-day avg
Today vs avg
Option Volume
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Option Chain Statistics

ExpiryCall VolPut VolVol P/CCall OIPut OIOI P/CIV CallIV Call OI-WtdIV Call Vol-WtdIV PutIV Put OI-WtdIV Put Vol-Wtd
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Real-Time Option Chain

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LastVolOILastVolOI
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Calls vs Puts by Expiry

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Competitive positioning

How CNSP ranks across every disease it competes in

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See how CNSP ranks against every competitor across each disease it develops in: phase, best drug, trials and likelihood of approval.
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CNSP News

CNSP
Sep 1, 2026
CNSPGeneral

CNS Pharmaceuticals Details Business Development Strategy Driving Its Next Phase of Growth

CNS Pharmaceuticals has outlined its business development strategy in a recent virtual investor segment. Chief Business Officer Dylan Wenke discussed the company's focus on oncology and neurology, emphasizing a rigorous evaluation process for potential opportunities. The company aims to build a differentiated portfolio of assets that address significant unmet medical needs while creating long-term value for shareholders.

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CNSP
Aug 27, 2026
CNSPConferences/Events

CNS Pharmaceuticals Participates in the Virtual Investor “Why Now” On-Demand Conference

CNS Pharmaceuticals participated in the Virtual Investor 'Why Now' on-demand conference, where CEO Rami Levin discussed the company's strategic transformation and financial enhancements following a recent financing round. The company aims to build a portfolio of innovative therapies addressing significant unmet medical needs while focusing on long-term growth and shareholder value.

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CNSP
Aug 12, 2026
CNSPGeneral
▼ -8.9%on this news

CNS Pharmaceuticals Reports Second Quarter 2026 Results, Highlighting Strengthened Balance Sheet and Accelerated Execution of Strategic Transformation

CNS Pharmaceuticals reported strong second quarter results for 2026, highlighting a cash position of approximately $20 million following an oversubscribed financing round of $22.5 million. The company is executing a strategic transformation to diversify its pipeline beyond glioblastoma. Despite a net loss of $2.6 million, management remains optimistic about future growth and value creation.

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CNSP
Jun 8, 2026
CNSPGeneral

CNS Pharmaceuticals CFO, Steve O’Loughlin, Highlights Company’s Recent $22.5M Financing in Virtual Investor “What This Means” Segment

CNS Pharmaceuticals recently completed an oversubscribed $22.5 million financing, as discussed by CFO Steve O’Loughlin in a Virtual Investor segment. The financing reflects investor confidence in the company's strategic transformation and acquisition-focused approach. O’Loughlin emphasized the importance of institutional support for advancing the company's growth and creating long-term shareholder value.

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CNSP
May 20, 2026
CNSPGeneral
▲ +6.7%on this news

CNS Pharmaceuticals CEO, Rami Levin, Participates in Virtual Investor CEO Connect Segment Highlighting Company’s Recent Strategic Transformation Progress

CNS Pharmaceuticals participated in a Virtual Investor CEO Connect segment where CEO Rami Levin discussed the company's recent $22.5 million financing and its strategic pivot. He outlined the progress made and the company's plans for pipeline development aimed at enhancing shareholder value. Levin emphasized key milestones for investors to monitor moving forward.

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CNSP
May 14, 2026
CNSPGeneral
▼ -9.2%on this news

CNS Pharmaceuticals Reports First Quarter 2026 Financial Results and Highlights Strategic Transformation Progress

CNS Pharmaceuticals reported its first quarter 2026 financial results, highlighting a strategic transformation led by a new executive team. The company secured $22.5 million in financing to pursue acquisition opportunities for clinical-stage assets. Despite a net loss of approximately $4.9 million, the company aims to advance its pipeline and create long-term shareholder value.

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CNSP
May 13, 2026
CNSPGeneral
▼ -9.8%on this news· ran to -23% by day 3shared move

CNS Drug Delivery Technologies Are Reshaping Alzheimer’s and Biodefense Research

Oncotelic Therapeutics is progressing in the development of its intranasal nose-to-brain (N2B) delivery system aimed at improving CNS drug delivery, particularly for Alzheimer's disease and biodefense applications. The company has announced a strategic agreement with Lunai Bioworks to monetize its N2B delivery system for specific applications. Despite the innovative solutions being explored, challenges persist with the blood-brain barrier, resulting in a high failure rate for therapeutic candidates. The ongoing demand for effective CNS interventions underscores the importance of Oncotelic's technology in both civilian and biodefense contexts.

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CNSP
May 11, 2026
CNSPGeneral
▼ -7.3%on this news· ran to -31% by day 3shared move

CNS Drug Delivery Breakthroughs Unlock Significant Biotech Market Opportunities

Oncotelic Therapeutics is making strides in central nervous system (CNS) drug delivery by advancing technologies designed to bypass the blood-brain barrier (BBB). Their proprietary nose-to-brain (N2B) delivery system has garnered attention, particularly in the context of rising Alzheimer’s disease cases and biodefense needs. Recently, Oncotelic announced a strategic monetization with Lunai Bioworks concerning its N2B system, highlighting the growing demand for effective CNS drug delivery solutions. The emphasis on overcoming delivery challenges is seen as key to improving therapeutic outcomes for neurodegenerative diseases.

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CNSP
May 4, 2026
CNSPGeneral
▲ +239.2%on this news

CNS Pharmaceuticals Announces Oversubscribed $22.5 Million Private Placement Financing

CNS Pharmaceuticals has announced a successful private placement financing, raising approximately $22.5 million from notable healthcare investors. The funds will be utilized to acquire clinical-stage assets aligned with the company's new corporate strategy. CNS aims to enhance its pipeline and create near-term value for patients and shareholders.

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CNSP
Mar 11, 2026
CNSPGeneral
▼ -11.6%on this news· ran to -27% by day 3

CNS Pharmaceuticals Launches New Corporate Strategy Focused on Building a High-Value Neurology and Oncology Pipeline

CNS Pharmaceuticals has launched a new corporate strategy to develop a high-value pipeline in neurology and oncology. The newly formed executive team will focus on acquiring differentiated therapeutic assets, moving away from a singular focus on glioblastoma. The company plans to out-license legacy assets while prioritizing programs with strong clinical potential and unmet medical needs.

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CNSP
Mar 11, 2026
CNSPConferences/Events
▼ -11.6%on this news· ran to -27% by day 3shared move

cnspharma.com NASDAQ: CNSP March 2026 Investor Presentation 2 Forward Looking Statements This presentation incorporates information from materials filed with the SEC and contains forward - looking statements . All statem

CNS Pharmaceuticals has announced a strategic pivot under a new executive team aimed at repositioning the company for long-term success in neurology and oncology. The new strategy emphasizes disciplined capital allocation and a focus on high-value, unmet medical needs. A comprehensive review has led to the targeting of preclinical and clinical-stage programs that show significant commercial viability. Additional highlights include the potential out-licensing of legacy programs to unlock value for shareholders.

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CNSP
Mar 2, 2026
CNSPGeneral

CNS Pharmaceuticals Appoints Lynne Kelley, MD, FACS, as Chief Medical Officer, Completing Executive Leadership Team

CNS Pharmaceuticals has appointed Dr. Lynne Kelley as Chief Medical Officer, completing its executive leadership team. Dr. Kelley brings extensive experience in oncology and rare diseases, having successfully led numerous clinical programs and regulatory approvals globally. Her expertise is expected to drive the company's strategic growth and enhance its drug development pipeline.

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CNSP
Feb 17, 2026
CNSPGeneral
▼ -5.8%on this news

CNS Pharmaceuticals Appoints Multiple Key Executives to Drive Company’s Recently Initiated Strategic Transformation

CNS Pharmaceuticals has appointed key executives to its leadership team to support its strategic transformation. The new appointments include Steven O'Loughlin as CFO, Eric Faulkner as CTO, and Dylan Wenke as CBO, all effective March 2, 2026. The company aims to enhance operational execution and drive value creation through disciplined growth and a focus on pipeline optimization.

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CNSP
Jan 28, 2026
CNSPGeneral

CNS Pharmaceuticals Issues Letter to Shareholders - January 27, 2026

CNS Pharmaceuticals has issued a letter to shareholders from its new CEO, Rami Levin, outlining a strategic focus on pipeline optimization and value creation. Levin emphasizes the importance of addressing unmet medical needs and refining the development of their lead asset, TPI 287. The company aims to enhance its operational structure and ensure disciplined capital allocation to maximize shareholder returns.

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CNSP
Jan 27, 2026
CNSPGeneral

CNS Pharmaceuticals Issues Letter to Shareholders

CNS Pharmaceuticals has issued a letter to shareholders from its new CEO, Rami Levin, outlining a strategic focus on pipeline optimization and value creation. Levin emphasizes a patient-first approach and the importance of refining their lead asset, TPI 287, to enhance its clinical potential. The company aims to strengthen its operational execution and maintain transparent communication with shareholders.

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CNSP
Dec 17, 2025
CNSPGeneral
▼ -6.4%on this news

CNS Pharmaceuticals Announces CEO Transition

CNS Pharmaceuticals has announced the appointment of Rami Levin as the new CEO, succeeding John Climaco. Levin, an industry veteran with nearly 30 years of experience, is expected to lead the company through its next growth phase, focusing on the development of TPI 287, a promising anti-cancer drug. The transition aims to enhance the company's strategic direction and operational capabilities.

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CNSP
Nov 17, 2025
CNSPPhases

CNS Pharmaceuticals Reports Third Quarter 2025 Financial Results and Provides Corporate Update

CNS Pharmaceuticals reported its third quarter 2025 financial results, highlighting progress with its lead candidate TPI 287 for glioblastoma treatment. The company has sufficient cash to fund operations into mid-2026 and is preparing for a Phase 2 trial. Early data suggests TPI 287 may effectively cross the blood-brain barrier, enhancing treatment options for patients.

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CNSP
Nov 10, 2025
CNSPConferences/Events

CNS Pharmaceuticals Announces Acceptance of Three Abstracts for Poster Presentation at the Society of NueroOncology (SNO) 30th Annual Meeting

CNS Pharmaceuticals has announced that three of its abstracts have been accepted for poster presentations at the Society of NeuroOncology's 30th Annual Meeting. The presentations will cover the activity of Berubicin against pediatric diffuse midline glioma, the evaluation of TPI 287 in a Phase 2 trial for glioblastoma, and results from a clinical trial comparing Berubicin and Lomustine in glioblastoma patients. The event will take place in Honolulu, HI from November 19-23, 2025.

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CNSP
Sep 3, 2025
CNSPConferences/Events

CNS Pharmaceuticals to Present at the H.C. Wainwright 27th Annual Global Investment Conference

CNS Pharmaceuticals, Inc. will present at the H.C. Wainwright 27th Annual Global Investment Conference from September 8-10, 2025, in New York. The company will also hold one-on-one meetings with investors. Their drug candidate, TPI 287, has shown potential in treating CNS tumors and has been well-tolerated in clinical trials.

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About CNS Pharmaceuticals, Inc.

Houston, TX 8 employees cnspharma.com
Headquarters2100 WEST LOOP SOUTH, HOUSTON, TX, 77027
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