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Clearside Biomedical, Inc.

CLSDFDA catalysts, PDUFA dates & pipeline intelligence
$0.41
▼ -0.16 · -28.07%

Last traded Nov 28, 2025. This price is not current.

Financials

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Revenue
R&D Expenses
Operating CF
Total Assets
Total Liabilities
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52W LOW $0.3752W HIGH $17.10
Volume
2.77 M
Value Traded
1.18 M
Short % Float
1.16%
Days to Cover
1.0
-84.76%Week
-89.49%1 Month
-92.66%3 Month
-96.49%6 Month
-98.63%5 Year
-99.66%All Time

Cash Data

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  • Monthly Burn
  • Burn Trend
  • Dilution Risk
  • SEC Filing

Key Stats

Market Cap
2.15 M
EPS (TTM)
-5.06
P/E Ratio
-
Ent. Value
56.96 M
Total Shares
77.28 M
Float Shares
65.38 M
Insiders
21.04%
Institutions
13.28%

Upcoming Catalysts

FDA decisions, readouts and PDUFA dates · scored by probability of approval

Catalyst Drug / Treatment Stage Prob. of Approval Description Drug Type Therapeutic Area Source
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Every FDA decision, readout and PDUFA date, with drug type, therapeutic area and a PoA score you can trade on.
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PoA blends historical approval base rates, trial design score and FDA review track record.

CLSD Catalyst Timeline

Dated clinical, regulatory and corporate events for Clearside Biomedical, Inc.

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Every PDUFA date, readout, approval and corporate move, tiered by market impact and updated daily.
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Past FDA Catalysts and PDUFA Decisions

How CLSD actually traded into and out of each decision

Date Drug Catalyst Stage Reaction Event Move % Best Trade %
2025-02-12CLS-AX (axitinib injectable suspension) Phase 2b data readout Phase 2b
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Reaction: 30 trading days around the event · Event Move: close to close on decision day · Best Trade: peak run-up from entry 10 days before the decision

Drug Pipeline Intelligence

Pipeline Score
Pipeline Value
Valuation Signal
1
Drugs Scored
rNPV / MCap
Top Drug
Showing 1 of 6 assets
DrugIndicationPhasePTRSrNPVStatusEnrollVelocityDesignEst. CompletionML SignalLast Change
CLS-AX Small moleculeCompletedNCT04626128Neovascular Age-related Macular DegenerationPhase 2 COMPLETED 87Oct 13, 2022
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PTRS, rNPV, enrollment velocity, trial design quality and ML risk signals for every asset above.
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Clinical Trial Results

Readouts, endpoints and source filings for every CLSD program

Drug Name Indication Phase Date Trial Results SummaryTitleSource
CLS-AX neovascular age-related macular degenerationPhase 1/2a/2b2025-06-17well tolerated and demonstrated a positive safety profileRead MoreClearside Biomedical Announces Multiple Presentations to be Featured at the Clinical Trials at the Summit MeetingRead More
Scroll for more · summaries link to the source press release
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Inside Trades

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Monthly insider buys and sells against the stock price, with the insider sentiment reading.
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InsiderSideSharesPriceValueDate
Thorp ClayDirectorBuy 15,000 176,141 held$0.92 02/24/2025
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Hedge Fund 13F Activity

Fund % of Portfolio Current MV Shares Owned Activity
RTW INVESTMENTS, LP 0.2 % (-50 %) 10.47 M 3.81 M -9.53% ( -400.75 K)
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Every 13F position with quarter over quarter share flow and average entry price.
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Shares held by hedge funds each quarter, and who bought or sold.

Ownership Trends

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Insider and institutional ownership, quarter by quarter.

CLSD Short Interest

Shares sold short, counted twice a month.

1.16%
Short % of Float
of tradable shares sold short
757.2K
Shares Sold Short
+437.0% vs prior count
1.0 Low
Days to Cover
trading days of normal volume to buy every short share back
1.3M
Avg Daily Volume
the average used for days to cover
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Two years of days to cover and shares sold short, with every count and its change.
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Options Data

Option Volume

Open Interest
Call OI
Put OI
Put-Call Ratio
OI 30-day avg
Today vs avg
Option Volume
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Put Vol
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Today vs avg

Option Chain Statistics

ExpiryCall VolPut VolVol P/CCall OIPut OIOI P/CIV CallIV Call OI-WtdIV Call Vol-WtdIV PutIV Put OI-WtdIV Put Vol-Wtd
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Per-expiry call and put volume, open interest, put-call ratios and implied volatility.
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Real-Time Option Chain

CallsStrikePuts
LastVolOILastVolOI
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Live calls and puts by strike: last price, volume and open interest for every expiry.
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Calls vs Puts by Expiry

CallsPutsLog scale
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Competitive positioning

How CLSD ranks across every disease it competes in

Competitive Position is a premium feature
See how CLSD ranks against every competitor across each disease it develops in: phase, best drug, trials and likelihood of approval.
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CLSD News

About Clearside Biomedical, Inc.

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