Approval Probability 71%
TA Base Rate26%
Adjusted LOA41%
ML RiskLOW_RISK
| NCT ID | Title | Phase | Status | Enrollment | Velocity | Design | Start | Completion | Last Updated | Sites | Countries |
|---|---|---|---|---|---|---|---|---|---|---|---|
| NCT04738838 | Oxytocin on Cold Water Task Performance and Recovery | PHASE2 | COMPLETED | 17 | — | — | May 20, 2022 | Jul 29, 2022 | Apr 3, 2026 | 2 | United States |
Changes in code substitution scores as measured by the Defense Automated Neurobehavioral Assessment (DANA). Data will be measured in milliseconds for response time.
Changes in choice reaction time scores as measured by the Defense Automated Neurobehavioral Assessment (DANA). Data will be measured in milliseconds for response time.
Altered ocular response as measured by the I-Portal Portable Assessment System (i-PAS). Saccades will be monitored and counted throughout the duration of the assessment.
Altered ocular response as measured by the I-Portal Portable Assessment System (i-PAS). Number of blinks will be counted through the course of the assessment.
Altered ocular response in blink duration as measured by the I-Portal Portable Assessment System (i-PAS). Blink duration will be measured in milliseconds.
| Arm | Type | Description |
|---|---|---|
| Oxytocin Nasal Spray | EXPERIMENTAL | Single dose of intranasal oxytocin (48 IU) prior to testing protocol. |
| Placebo Nasal Spray | PLACEBO_COMPARATOR | Single dose of intranasal treatment with placebo (identical to oxytocin nose spray minus the oxytocin) |
| Name | Type | Description |
|---|---|---|
| Oxytocin nasal spray | DRUG | Intranasal treatment with oxytocin via nasal spray (48 IU per dose) |
| Placebo nasal spray | DRUG | Intranasal treatment with placebo via nasal spray |
Inclusion Criteria: * Recreationally skilled swimmers Exclusion Criteria: * Smoking/vaping, a history of psychiatric disorders, safety requirements related to the oxytocin administration \[hypersensitivity to oxytocin or vasopressin, history of hyponatremia, syndrome of inappropriate antidiuretic...