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StimRouter System

Phase 1

Unilateral Carpal Tunnel Syndrome | Unknown | Other |Bioventus Inc.|Last Updated: Jun 6, 2016

Success Probability

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Market & Valuation

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Trial Design

UNCONTROLLEDBiomarker
Total Trials1
Total Enrollment10

FDA Designations

No designations recorded

Clinical trial landscape

StimRouter System · 1 trial · 1 indication

Phase 1 1
NCT00665132Acute Human Study: StimRouter for Peripheral Nerve Stimulation of Discrete Peripheral NervesUnilateral Carpal Tunnel Syndrome
COMPLETED10 Analytics
PHASE1COMPLETED
Acute Human Study: StimRouter for Peripheral Nerve Stimulation of Discrete Peripheral Nerves
Unilateral Carpal Tunnel SyndromeUnlock trial analytics

Study Endpoints

Primary Endpoints

Implant Success
at device implantation procedure

Success of device implantation was defined as uncomplicated minimally-invasive implantation of the StimRouter Lead near the targeted peripheral median nerve, resulting in production of desired paresthesias in the sensory distribution of the median nerve when active peripheral nerve stimulation was applied. This outcome parameter was intended to serve as an indication that the lead and electrode stimulating positions could be correctly placed while still maintaining the minimal invasiveness of the procedure. Fluoroscopic imaging was used to document positioning of the StimRouter Lead and, by applying stimulation from a commercially available Dakmed External Pulse Generator (EPG) to the StimRouter Lead, desired paresthesia response was confirmed.

Secondary Endpoints

Patent Satisfaction
Day 5 after final stimulation
Percent of Participants Reporting Pain Change From Baseline to Day 5
Day 5
Mean Change in Pain Achieved by Participants Who Reported Pain Change From Baseline to Day 5
Day 5 after final stimulation
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Study Design & Arms

AllocationNA
MaskingNONE
ModelSINGLE_GROUP
PurposeTREATMENT

Treatment Arms

ArmTypeDescription
StimRouter (SR) for CTSEXPERIMENTALPercutaneous implantation of StimRouter System

Interventions

NameTypeDescription
StimRouter SystemDEVICEImplanted with StimRouter System receive 6 hours (or less if not tolerated by the Subject)of electrical therapeutic stimulation each day for a total of 5 days (from start of successful programming)
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Eligibility Criteria

Age Range18 Years to N/A
SexALL
Healthy VolunteersNo
Study Sites1

Inclusion Criteria: * 18 years of age or older * Chronic peripheral pain persisting for greater than or equal to 3 months diagnosed previously as a mononeuropathy of the median nerve at the level of the carpal tunnel (i.e., diagnosed CTS) * Average chronic pain level greater than or equal to 5/10 \...

Countries:United States
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Frequently asked questions about StimRouter System

What is the StimRouter System used for?

The StimRouter System is used for unilateral Carpal Tunnel Syndrome. It is an investigational device being studied as a peripheral nerve stimulation treatment for this condition. The system is currently in Phase 1 clinical development and is not yet approved by the FDA.

Who makes the StimRouter System?

The StimRouter System is being developed by Bioventus Inc., a company traded on the NASDAQ under the ticker symbol BVS. The company is conducting clinical research to evaluate the device for the treatment of unilateral Carpal Tunnel Syndrome.

What phase is the StimRouter System in?

The StimRouter System is in Phase 1 clinical development. It is an investigational device and has not been approved by the FDA. One Phase 1 study has been completed to evaluate its safety and performance in patients with unilateral Carpal Tunnel Syndrome.

What clinical trials is the StimRouter System in?

The StimRouter System has one completed clinical trial, NCT00665132, titled 'Acute Human Study: StimRouter for Peripheral Nerve Stimulation of Discrete Peripheral Nerves.' This Phase 1 study enrolled 10 participants with unilateral Carpal Tunnel Syndrome in the United States and has been completed.

Is the StimRouter System the same as other nerve stimulation devices?

The StimRouter System is a specific peripheral nerve stimulation device developed by Bioventus Inc. for unilateral Carpal Tunnel Syndrome. It is not known to be the same as any other named device, and no alternative names have been associated with it in clinical trial records.