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BioRestorative Therapies, Inc.

BRTX
Richly ValuedBiotech · Clinical
FDA catalysts, PDUFA dates & pipeline intelligence
$1.89
▲ +0 · +0.02%

Financials

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52W LOW $0.1452W HIGH $3.23
Volume
15.72 K
Value Traded
56.66 K
Short % Float
0.9%
-12.15%Week
-31.39%1 Month
+444.93%3 Month
+681.38%6 Month
-99.37%5 Year
-100%All Time

Cash Data

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Key Stats

Market Cap
2.61 M
EPS (TTM)
-8.01
P/E Ratio
-
Ent. Value
-981.15 K
Total Shares
1.38 M
Float Shares
1.29 M
Insiders
6.74%
Institutions
13.83%

Upcoming Catalysts

FDA decisions, readouts and PDUFA dates · scored by probability of approval

Catalyst Drug / Treatment Stage Prob. of Approval Description Drug Type Therapeutic Area Source
Phase 2 data readout
BRTX-100 (autologous hypoxically cultured mesenchymal stem cell therapy)
chronic lumbar disc disease (cLDD)
Fast Track
Phase 2Cell TherapiesMusculoskeletal System
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Every FDA decision, readout and PDUFA date, with drug type, therapeutic area and a PoA score you can trade on.
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PoA blends historical approval base rates, trial design score and FDA review track record.

BRTX Catalyst Timeline

Dated clinical, regulatory and corporate events for BioRestorative Therapies, Inc.

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Every PDUFA date, readout, approval and corporate move, tiered by market impact and updated daily.
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Past FDA Catalysts and PDUFA Decisions

How BRTX actually traded into and out of each decision

Date Drug Catalyst Stage Reaction Event Move % Best Trade %
2026-05-06BRTX-100 (autologous cultured mesenchymal stem cells) Phase 2 data readout Phase 2
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Reaction: 30 trading days around the event · Event Move: close to close on decision day · Best Trade: peak run-up from entry 10 days before the decision

Drug Pipeline Intelligence

D20 / 100
Pipeline Score
$0M
Pipeline Value
Richly Valued
Valuation Signal
1
Drugs Scored
0.1x
rNPV / MCap
Top 94%
Micro Cap
(rank 619 of 658)
Percentile Rank
BioRestorative Therapies, Inc. faces pipeline headwinds (20/100), with $185M risk-adjusted pipeline value, led by BRTX-100 in Lumbar Disc Disease (Phase 2), but cash runway is a concern.
Showing 1 of 1 assets
DrugIndicationPhasePTRSrNPVStatusEnrollVelocityDesignEst. CompletionML SignalLast Change
BRTX-100 Monoclonal antibodyNCT04042844Lumbar Disc DiseasePhase 2 RECRUITING 99Dec 1, 2027
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Clinical Trial Results

Readouts, endpoints and source filings for every BRTX program

Drug Name Indication Phase Date Trial Results SummaryTitleSource
BRTX-100
Fast Track
chronic lumbar disc diseasePhase 22026-05-0752% of evaluable patients achieving at least 50% improvement in both VAS pain and ODI function measuresRead MoreBioRestorative Therapies Reports Expanded Phase 2 Blinded Dataset for BRTX-100 Showing Sustained Pain and Functional Improvements in Chronic Lumbar Disc DiseaseRead More
Scroll for more · summaries link to the source press release
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Inside Trades

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Monthly insider buys and sells against the stock price, with the insider sentiment reading.
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InsiderSideSharesPriceValueDate
Broadrick Dale10% OwnerSell -1,112 445,933 held$1.58 10/28/2024
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Hedge Fund 13F Activity

Fund % of Portfolio Current MV Shares Owned Activity
No hedge fund reported a 13F position in BRTX for Q2 2026.
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Every 13F position with quarter over quarter share flow and average entry price.
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Shares held by hedge funds each quarter, and who bought or sold.

BRTX Institutional Ownership Trends

Options Data

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Option Chain Statistics

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Real-Time Option Chain

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Calls vs Puts by Expiry

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Competitive positioning

How BRTX ranks across every disease it competes in

Competitive Position is a premium feature
See how BRTX ranks against every competitor across each disease it develops in: phase, best drug, trials and likelihood of approval.
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BRTX News

BRTX
Sep 2, 2026
BRTXGeneral
▼ -28.8%on this news

BioRestorative Therapies Announces Reverse Stock Split

BioRestorative Therapies, Inc. announced a 1-for-20 reverse stock split to comply with Nasdaq's minimum bid price requirement. The split will reduce the number of shares from approximately 27.6 million to about 1.38 million, effective September 7, 2026. The company aims to stabilize its stock price and maintain compliance with listing standards.

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BRTX
Jun 25, 2026
BRTXPhases

BioRestorative Therapies Announces Completion of BRTX-100 Phase 2 Manufacturing, Highlighting Integrated Regenerative Biologics Platform

BioRestorative Therapies has successfully completed the manufacturing of BRTX-100 for its Phase 2 clinical trial, a significant milestone for the company. This achievement highlights the strength of its integrated regenerative medicine platform, which allows for high-quality biologic production. The company aims to advance its regenerative biologics across therapeutic and aesthetic markets, improving operational costs and margins.

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BRTX
Jun 18, 2026
BRTXGeneral

BioRestorative Therapies Strengthens Leadership with Appointment of Healthcare Executive Zachary Smith as Vice President of Biocosmeceuticals Division to Accelerate Commercial Expansion and Strategic Growth

Accomplished commercial aesthetics veteran to drive sales channel expansion and pipeline development MELVILLE, N.Y., June 18, 2026 (GLOBE NEWSWIRE) -- BioRestorative Therapies, Inc. (“BioRestorative,” “BRTX,” or the “Company”) (Nasdaq:BRTX), a late-stage clinical regenerative me

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BRTX
May 26, 2026
BRTXPhases
▲ +20.1%on this news· ran to +130% by day 3

BioRestorative Completes Phase 2 Dosing of BRTX-100, Advancing Lead Regenerative Spine Program Toward 2027 Topline Data

Fully enrolled, randomized, double-blind, sham-controlled Phase 2 study has completed treatment administration in 99 patients; Company continues Phase 3 readiness activities following FDA Type B meeting alignment MELVILLE, N.Y., May 26, 2026 (GLOBE NEWSWIRE) -- BioRestorative Th

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BRTX
May 13, 2026
BRTXConferences/Events

BioRestorative Therapies Presents New Preclinical Data at ISCT 2026 Highlighting Source-Specific Exosome Functionality and Commercial Applications in BioCosmeceuticals

BioRestorative Therapies presented new preclinical data at ISCT 2026, showcasing the distinct functional signatures of MSC-derived extracellular vesicles. The findings suggest targeted therapeutic applications across regenerative medicine and aesthetics. The company aims to align biological functions with clinical outcomes, enhancing its BioCosmeceutical platform for skin health and recovery solutions.

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BRTX
May 7, 2026
BRTXPhases
▼ -8.1%on this news· ran to -19% by day 3

BioRestorative Therapies Reports Expanded Phase 2 Blinded Dataset for BRTX-100 Showing Sustained Pain and Functional Improvements in Chronic Lumbar Disc Disease

Oral presentation at ISCT 2026 included larger 52-week follow-up cohort, with 52% of evaluable patients achieving at least 50% improvement in both VAS pain and ODI function measures and no dose-limiting toxicity safety signals observed MELVILLE, N.Y., May 07, 2026 (GLOBE NEWSWIR

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BRTX
Apr 30, 2026
BRTXPhases
▲ +11.6%on this news· ran to +26% by day 3

BioRestorative Therapies to Present New Data at ISCT 2026 Highlighting Its Ongoing Phase 2 Clinical Trial in Chronic Lumbar Disease and Its BioCosmeceutical Platform

Data demonstrate progress in each of its MSC-derived programs MELVILLE, N.Y., April 30, 2026 (GLOBE NEWSWIRE) -- BioRestorative Therapies, Inc. ("BioRestorative," "BRTX," or the "Company") (Nasdaq: BRTX), a late-stage clinical regenerative medicine company focused on stem cell-b

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BRTX
Apr 21, 2026
BRTXGeneral
▼ -7.8%on this news

BioRestorative Therapies Announces Strategic Partnership with Global Dermatology Leader Dr. David J. Goldberg to Lead Clinical Evaluation and Seek Multi-Channel Adoption of Its Regenerative BioCosmeceutical Platform

Collaboration establishes an independent clinical validation pathway, expands access to influential physician networks, and strengthens the foundation for possible broad commercial growth across professional, biologic dermal, and consumer channels MELVILLE, N.Y., April 21, 2026

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BRTX
Apr 7, 2026
BRTXGeneral

BioRestorative Therapies Announces Strategic Collaboration with 203 Creates to Build and Commercialize Biocosmeceutical Platform

Partnership to drive brand architecture, go-to-market execution, and global launch of the Company’s product portfolio bridging biotechnology and premium skincare MELVILLE, N.Y., April 07, 2026 (GLOBE NEWSWIRE) -- BioRestorative Therapies, Inc. (“BioRestorative,” “BRTX,” or the “

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BRTX
Mar 30, 2026
BRTXPhases
▼ -10.9%on this news

BioRestorative Therapies Reports Positive Phase 2 Blinded Data for BRTX-100 Demonstrating Meaningful Improvements in Pain and Function in Chronic Lumbar Disc Disease

Data showed 50% or more of patients reporting >50% improvement in key pain and function scales No adverse events related to dose-limiting toxicities associated with hypoxic-cultured mesenchymal stem cells Presented at the 2026 Orthopaedic Research Society Annual Meeting MELVIL

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BRTX
Mar 19, 2026
BRTXPhases
▲ +11.9%on this news· ran to +28% by day 3

BioRestorative Therapies to Present Positive Phase 2 Blinded Data for BRTX-100 Demonstrating Meaningful Improvements in Pain and Function in Chronic Lumbar Disc Disease

New blinded data from ~45 patients to date in key pain and function scales and safety and tolerability of the Company’s proprietary hypoxic-cultured mesenchymal stem cells to be unveiled on March 28th at the 2026 Orthopaedic Research Society Annual Meeting MELVILLE, N.Y., March

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BRTX
Mar 5, 2026
BRTXConferences/Events

BioRestorative Therapies, Inc. to Participate in the Be+Well Beauty and Wellness Show in New York City, March 8-10, 2026

BioRestorative Therapies, Inc. will participate in the Be+Well Beauty and Wellness Show in New York City from March 8-10, 2026. The event aims to expand awareness and distribution of its BioCosmeceutical platform, which utilizes regenerative biologics technology. The company seeks to engage with potential partners and showcase its innovative skincare solutions. This participation is part of a broader strategy to enhance commercialization efforts and clinical pipeline advancements.

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BRTX
Mar 4, 2026
BRTXGeneral

BioRestorative Therapies, Inc. Issues Letter to Shareholders Highlighting Major Milestones, Regulatory Alignment, Clinical Execution and Capital Strategy

BioRestorative Therapies, Inc. has reported significant progress, including the completion of its Phase 2 trial enrollment for BRTX-100 and a positive FDA Type B meeting outcome. The company is also advancing its BioCosmeceutical platform and has strengthened its capital position through a recent public offering. These milestones position BioRestorative for potential growth and regulatory clarity in the coming years.

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BRTX
Feb 24, 2026
BRTXFDA Updates
▲ +37%on this news

BioRestorative Expands Global Protection for ThermoStem®, a Potentially Longer-Lasting and Safer Cell-Based Alternative to GLP-1 Drugs

BioRestorative Therapies has received patent approval in Australia for its ThermoStem technology, which utilizes brown adipose-derived stem cells to address obesity and metabolic disorders. This patent enhances the company's competitive edge against GLP-1 drugs. CEO Lance Alstodt emphasized the importance of this development in strengthening their global patent portfolio and advancing their mission in regenerative medicine.

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BRTX
Feb 14, 2026
BRTXGeneral
▼ -6.3%on this news· ran to -23% by day 3

BioRestorative Announces Closing of $5.0 Million Public Offering

MELVILLE, N.Y., Feb. 13, 2026 (GLOBE NEWSWIRE) -- BioRestorative Therapies, Inc. (“BioRestorative”, “BRTX” or the “Company”) (NASDAQ:BRTX), a late stage clinical regenerative medicine innovator focused on stem cell-based therapies and products, today announced the closing of its

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BRTX
Feb 12, 2026
BRTXGeneral
▼ -40.5%on this newsshared move

BioRestorative Announces Pricing of $5.0 Million Public Offering

BioRestorative Therapies, Inc. has announced a public offering of 14,285,715 shares at $0.35 each, aiming to raise approximately $5 million. The proceeds will be allocated to clinical trials for BRTX-100, pre-clinical research for the ThermoStem Program, and general corporate purposes. The offering is expected to close on February 13, 2026.

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BRTX
Feb 11, 2026
BRTXFDA Updates
▼ -35.4%on this news· ran to -62% by day 1shared move

BioRestorative Announces Positive Outcome from Type B Meeting with FDA

BioRestorative Therapies announced a positive outcome from a Type B meeting with the FDA regarding its BRTX-100 program for chronic lumbar disc disease. The FDA's feedback supports a potential expedited Biologics License Application approval pathway. The company plans to submit a Phase 3 IND application in the latter half of 2026, highlighting the program's promising safety and efficacy data.

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BRTX
Feb 10, 2026
BRTXPhases
▼ -38.9%on this news· ran to -73% by day 3shared move

BioRestorative Completes Patient Enrollment in Landmark Phase 2 Trial of BRTX-100 for Chronic Lumbar Disc Disease

BioRestorative Therapies has completed patient enrollment in its Phase 2 trial for BRTX-100, targeting chronic lumbar disc disease. With 99 patients enrolled at 15 clinical sites, this trial is among the largest in its category. The study aims to assess both safety and efficacy through a randomized, double-blind design. Positive preliminary data has been shared at leading scientific conferences, paving the way for potential Phase 3 development.

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BRTX
Nov 17, 2025
BRTXFDA Updates
▼ -6.8%on this news

BioRestorative Granted Type B Meeting with FDA to Discuss Accelerated BLA Approval Pathway for BRTX-100 in Chronic Lumbar Disc Disease

MELVILLE, N.Y., Nov. 17, 2025 (GLOBE NEWSWIRE) -- BioRestorative Therapies, Inc. (“BioRestorative”, “BRTX” or the “Company”) (NASDAQ:BRTX), a regenerative medicine innovator focused on stem cell-based therapies and products, today announced that it has been granted a Type B meeti

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BRTX
Nov 12, 2025
BRTXGeneral
▼ -9.4%on this newsshared move

BioRestorative Therapies Reports Third Quarter 2025 Financial Results and Provides Business Update

BioRestorative Therapies reported its third quarter 2025 financial results, showing a revenue of approximately $11,800, a decrease from $233,600 in Q3-2024. The company experienced a net loss of $3.0 million for the quarter, higher than the previous year's loss. Despite these challenges, the CEO expressed optimism about future growth opportunities in clinical development and the BioCosmeceutical platform.

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About BioRestorative Therapies, Inc.

Melville, NY 14 employees biorestorative.com
Headquarters40 MARCUS DRIVE, MELVILLE, NY, 11747
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