Approval Probability 71%
TA Base Rate26%
Adjusted LOA41%
ML RiskLOW_RISK
| NCT ID | Title | Phase | Status | Enrollment | Velocity | Design | Start | Completion | Last Updated | Sites | Countries |
|---|---|---|---|---|---|---|---|---|---|---|---|
| NCT03197779 | A Short and Long Intravenous Infusion Study to Evaluate the Safety, Pharmacokinetics, and Pharmacodynamics of BMS-962212 in Healthy Subjects | PHASE1 | COMPLETED | 691 | — | — | Nov 18, 2013 | Jan 24, 2017 | Jul 2, 2017 | 3 | United States |
measured by incidence
measured by incidence
measured by incidence
measured by incidence
measured by incidence
measured by incidence
measured by incidence
measured by ECG
measured by ECG
measured by ECG
measured by telemetry
measured by iohexol administration plasma clearance and the Chronic Kidney Disease-Epidemiology Collaborative Group (CKD EPI) equation
measured by serum biomarkers
measured by urine biomarkers
measured by urine biomarkers
| Arm | Type | Description |
|---|---|---|
| BMS-962212 Two Hour Administration | EXPERIMENTAL | Intravenous administered over 2 hours of BMS-962212 |
| BMS-962212 5 Day Administration | EXPERIMENTAL | Intravenous administered over 5 days of BMS-962212 |
| BMS-962212 and Aspirin | EXPERIMENTAL | BMS-962212 intravenous administration, followed by aspirin oral administration, then combination administration of BMS-962212 and aspirin |
| Placebo and Aspirin | PLACEBO_COMPARATOR | Placebo intravenous administration, followed by aspirin, then combination administration of placebo and aspirin |
| Placebo | PLACEBO_COMPARATOR | Placebo intravenous administration |
| Name | Type | Description |
|---|---|---|
| BMS-962212 | DRUG | Intravenous Infusion administration over 2 hours or 5 days |
| Aspirin | DRUG | Oral administration |
| Placebo | OTHER | Oral administration |
For more information regarding Bristol-Myers Squibb Clinical Trial participation, please visit www.BMSStudyConnect.com Inclusion Criteria: * Healthy subjects as determined by no clinically significant deviation from normal in medical history, physical examination, ECG, and clinical laboratory dete...