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Penumbra, Inc.

PENFDA catalysts, PDUFA dates & pipeline intelligence
$324.95
▲ +0.56 · +0.17%

Financials

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52W LOW $221.2652W HIGH $362.41
Volume
165.43 K
Value Traded
63.47 M
Short % Float
5.87%
Days to Cover
4.8
+0.86%Week
+1.88%1 Month
+1.78%3 Month
-0.85%6 Month
+29.16%5 Year
+721.73%All Time

Cash Data

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  • Monthly Burn
  • Burn Trend
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  • SEC Filing

Key Stats

Market Cap
12.80 B
EPS (TTM)
4.08
P/E Ratio
79.76
Ent. Value
12.15 B
Total Shares
39.39 M
Float Shares
38.26 M
Insiders
2.87%
Institutions
87.22%

Upcoming Catalysts

FDA decisions, readouts and PDUFA dates · scored by probability of approval

Catalyst Drug / Treatment Stage Prob. of Approval Description Drug Type Therapeutic Area Source
PDUFA
2026
Example Drug
Treatment for example condition requiring FDA review
Phase 3Small MoleculeOncology-
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Every FDA decision, readout and PDUFA date, with drug type, therapeutic area and a PoA score you can trade on.
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PoA blends historical approval base rates, trial design score and FDA review track record.

PEN Catalyst Timeline

Dated clinical, regulatory and corporate events for Penumbra, Inc.

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Every PDUFA date, readout, approval and corporate move, tiered by market impact and updated daily.
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Past FDA Catalysts and PDUFA Decisions

How PEN actually traded into and out of each decision

Date Drug Catalyst Stage Reaction Event Move % Best Trade %
-Example Drug Phase 3 data readout Phase 3
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Reaction: 30 trading days around the event · Event Move: close to close on decision day · Best Trade: peak run-up from entry 10 days before the decision

Drug Pipeline Intelligence

Pipeline Score
Pipeline Value
Valuation Signal
1
Drugs Scored
rNPV / MCap
Top Drug
Top 89%
Mid Cap
(rank 585 of 657)
Percentile Rank
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DrugIndicationPhasePTRSrNPVStatusEnrollVelocityDesignEst. CompletionML SignalLast Change
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PTRS, rNPV, enrollment velocity, trial design quality and ML risk signals for every asset above.
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Clinical Trial Results

Readouts, endpoints and source filings for every PEN program

Drug Name Indication Phase Date Trial Results SummaryTitleSource
computer-assisted vacuum thrombectomy (CAVT) pulmonary embolism2026-10-06Total daily step count, walking bout length, number of walking bouts, walking bout duration and peak 10-minute step count were significantly correlated with 30-day 6-minute walk test performance.; Correlations were strongest with temporally matched wearable and clinic data at 30 days and attenuated with 90-day follow up data.Read MoreNew STORM-PE Data Demonstrate Correlation Between Clinical Assessments and Real-world Functional Recovery Captured Through Wearable Technology in Patients with Pulmonary EmbolismRead More
Scroll for more · summaries link to the source press release
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Inside Trades

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Monthly insider buys and sells against the stock price, with the insider sentiment reading.
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InsiderSideSharesPriceValueDate
Elsesser AdamDirector, Officer (CEO)Disposition -77,000 683,042 held$0.00 05/19/2026
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Hedge Fund 13F Activity

Fund % of Portfolio Current MV Shares Owned Activity
PFM HEALTH SCIENCES, LP 1.6 % (-61.9 %) 19.01 M 60.22 K -56.92% ( -79.56 K)
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Shares held by hedge funds each quarter, and who bought or sold.

PEN Institutional Ownership Trends

PEN Short Interest

Shares sold short, counted twice a month.

5.87%
Short % of Float
of tradable shares sold short
2.2M
Shares Sold Short
+24.3% vs prior count
4.8 Moderate
Days to Cover
trading days of normal volume to buy every short share back
472.6K
Avg Daily Volume
the average used for days to cover
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Two years of days to cover and shares sold short, with every count and its change.
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Options Data

Option Volume

Open Interest
Call OI
Put OI
Put-Call Ratio
OI 30-day avg
Today vs avg
Option Volume
Call Vol
Put Vol
Put-Call Ratio
Vol 30-day avg
Today vs avg

Option Chain Statistics

ExpiryCall VolPut VolVol P/CCall OIPut OIOI P/CIV CallIV Call OI-WtdIV Call Vol-WtdIV PutIV Put OI-WtdIV Put Vol-Wtd
2026-11-20
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Per-expiry call and put volume, open interest, put-call ratios and implied volatility.
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Real-Time Option Chain

CallsStrikePuts
LastVolOILastVolOI
No data available
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Calls vs Puts by Expiry

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Competitive positioning

How PEN ranks across every disease it competes in

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See how PEN ranks against every competitor across each disease it develops in: phase, best drug, trials and likelihood of approval.
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PEN News

PEN
Oct 20, 2026
PENFDA Updates

Penumbra's CAVT Technology Receives FDA Clearance for the Treatment of Deep Vein Thrombosis (DVT)

Penumbra, Inc. has received FDA clearance for its Lightning™ computer assisted vacuum thrombectomy (CAVT™) technology for treating deep vein thrombosis (DVT). This approval follows positive results from the BOLT-DVT trial, which showed the technology's safety and efficacy, including rapid clot removal and significant patient-reported improvements in pain and quality of life. The trial highlighted the potential of CAVT to enhance DVT treatment protocols.

Read more →
PEN
Oct 6, 2026
PENPhases

New STORM-PE Data Demonstrate Correlation Between Clinical Assessments and Real-world Functional Recovery Captured Through Wearable Technology in Patients with Pulmonary Embolism

Penumbra, Inc. announced positive results from the STORM-PE trial, showing a correlation between real-world activity tracked by wearables and clinical assessments in pulmonary embolism patients. The trial demonstrated that patients receiving computer-assisted vacuum thrombectomy (CAVT) plus anticoagulation had better recovery outcomes compared to those on anticoagulation alone. These findings were presented at the VIVA meeting, highlighting the potential of wearables in enhancing patient care.

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PEN
Aug 25, 2026
PENGeneral

Incuvate Files Patent Infringement Lawsuit Against Penumbra

Incuvate, LLC has initiated a patent infringement lawsuit against Penumbra, Inc. in the U.S. District Court for the Northern District of California. The lawsuit claims that Penumbra's THUNDERBOLT Neurovascular Thrombectomy System infringes on five of Incuvate's patents related to real-time aspiration monitoring technology. Incuvate seeks damages and injunctive relief, alleging unauthorized use of their patented technology.

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PEN
Jul 30, 2026
PENGeneral

Penumbra, Inc. Reports Second Quarter 2026 Financial Results

Penumbra, Inc. reported strong financial results for Q2 2026, with revenues reaching $390 million, a 14.9% increase from the previous year. The company saw notable growth in both thrombectomy and embolization segments. However, due to a pending acquisition by Boston Scientific, Penumbra will not provide financial guidance for the remainder of the year.

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PEN
Jul 22, 2026
PENPhases

THUNDER Study Demonstrates Penumbra's THUNDERBOLT is Safe and Effective for Stroke Care

The THUNDER study has shown that Penumbra's THUNDERBOLT device is both safe and effective for treating stroke patients with emergent large vessel occlusion. The device demonstrated a high rate of complete clot ingestion and low complication rates. With a median time-to-revascularization of just 20 minutes, the study results support the advancement of mechanical thrombectomy technologies. THUNDERBOLT has also received FDA clearance and CE Mark.

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PEN
Jul 7, 2026
PENPhases

First Patient Enrolled in Penumbra's FORWARD Study Evaluating Mechanical Thrombectomy and Computer Assisted Vacuum Thrombectomy for Distal Acute Ischemic Stroke

Penumbra, Inc. has initiated its FORWARD study, focusing on mechanical thrombectomy for distal acute ischemic strokes. The study aims to evaluate the safety and efficacy of its RED reperfusion catheter portfolio, which includes the THUNDERBOLT CAVT platform. The first patient has been treated, marking a key milestone in addressing a challenging patient population with limited treatment options.

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PEN
Jun 15, 2026
PENFDA Updates

Penumbra Expands CAVT for Stroke to Europe with CE Mark for THUNDERBOLT

Penumbra, Inc. has received CE Mark approval for its THUNDERBOLT technology, which enables advanced computer-assisted vacuum thrombectomy for acute ischemic stroke. This marks a significant step in expanding access to innovative stroke care in Europe, following recent FDA clearance in the U.S. The technology aims to enhance patient outcomes and streamline treatment procedures.

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PEN
Jun 11, 2026
PENFDA Updates

Penumbra's THUNDERBOLT Receives FDA Clearance - Bringing Computer Assisted Vacuum Thrombectomy Technology to Stroke

Penumbra, Inc. has received FDA clearance for its THUNDERBOLT technology, the first computer-assisted vacuum thrombectomy platform aimed at treating acute ischemic stroke. This innovative system enhances clot removal efficiency and safety, potentially improving patient recovery outcomes. THUNDERBOLT is set to redefine stroke management by minimizing catheter manipulation and ensuring complete clot capture.

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PEN
May 6, 2026
PENGeneral

Penumbra, Inc. Reports First Quarter 2026 Financial Results

Penumbra, Inc. reported strong financial results for Q1 2026, with revenues reaching $374.8 million, a 15.6% increase from the previous year. The company saw significant growth in both thrombectomy and embolization revenues. However, it has opted not to provide financial guidance for the full year due to its pending acquisition by Boston Scientific Corporation.

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PEN
Apr 13, 2026
PENPhases

New STORM-PE Data Show Computer Assisted Vacuum Thrombectomy with Anticoagulation Resulted in Significantly Better Functional Outcomes at 90 Days Compared to Anticoagulation Alone for Pulmonary Embolism Patients

Penumbra, Inc. announced positive 90-day results from the STORM-PE trial, showing that patients with acute intermediate-high risk pulmonary embolism treated with computer assisted vacuum thrombectomy (CAVT) plus anticoagulation had significantly better functional outcomes compared to those receiving anticoagulation alone. The trial demonstrated improvements in walking distance and functional status, highlighting the potential of CAVT in enhancing patient recovery.

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PEN
Feb 25, 2026
PENGeneral

Penumbra, Inc. Reports Fourth Quarter and Full Year 2025 Financial Results

Penumbra, Inc. reported strong financial results for Q4 and full year 2025, with total revenue reaching $385.4 million for Q4, a 22.1% increase from the previous year. The company also saw a rise in gross profit margin and income from operations. However, it will not provide guidance for 2026 due to a pending acquisition by Boston Scientific.

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PEN
Jan 15, 2026
PENGeneral
▲ +11.8%on this newsshared move

Penumbra, Inc. Provides Preliminary Update on Fourth Quarter and Full Year 2025 Financial Results

Penumbra reported preliminary fourth quarter revenue between $383.0 million and $384.8 million. This marks growth of approximately 21.4% to 22.0% compared to the prior year period. Full year revenue reached $1,401.3 million to $1,403.1 million. That represents an increase of roughly 17.3% to 17.5% over 2024 results.

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PEN
Dec 29, 2025
PENConferences/Events

Penumbra, Inc. to Present at the 44th Annual J.P. Morgan Healthcare Conference

Penumbra, Inc. is set to present at the 44th Annual J.P. Morgan Healthcare Conference on January 12, 2026. The presentation will be available via a webcast on the company's website for at least two weeks post-event. Penumbra is known for its innovative thrombectomy technologies aimed at improving patient outcomes in various medical conditions.

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PEN
Nov 19, 2025
PENConferences/Events

Penumbra, Inc. to Present at the Piper Sandler 37th Annual Healthcare Conference

Penumbra, Inc. announced that its management team will present at the Piper Sandler 37th Annual Healthcare Conference on December 3, 2025. The presentation will be accessible via a webcast on the company's website, which will remain available for two weeks post-event. Penumbra focuses on innovative thrombectomy technologies aimed at improving patient outcomes.

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PEN
Nov 5, 2025
PENGeneral
▲ +17.3%on this news

Penumbra, Inc. Reports Third Quarter 2025 Financial Results

Penumbra, Inc. reported strong financial results for Q3 2025, with total revenue reaching $354.7 million, a 17.8% increase from the previous year. The company also raised its full-year revenue guidance to between $1.375 billion and $1.380 billion, reflecting confidence in continued growth. Gross profit margin improved to 67.8%, although operating expenses rose compared to the prior year.

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PEN
Nov 3, 2025
PENPhases

Latest Data from Landmark STORM-PE Randomized Controlled Trial Demonstrate that CAVT with Anticoagulation Significantly Improves Functional Outcomes for Patients with Pulmonary Embolism

Penumbra, Inc. announced positive results from the STORM-PE trial, showing that computer-assisted vacuum thrombectomy (CAVT) combined with anticoagulation significantly improves functional outcomes for patients with acute pulmonary embolism. The trial demonstrated superior thrombus reduction and recovery rates compared to anticoagulation alone. These findings highlight the importance of early intervention and may influence future treatment guidelines.

Read more →
PEN
Oct 27, 2025
PENPhases

Landmark STORM-PE Randomized Controlled Trial Finds Computer Assisted Vacuum Thrombectomy (CAVT) with Anticoagulation Superior to Traditional Anticoagulation Treatment for Pulmonary Embolism

Penumbra, Inc. announced positive results from the STORM-PE trial, demonstrating that computer assisted vacuum thrombectomy (CAVT) combined with anticoagulation significantly reduces right heart strain in patients with acute pulmonary embolism compared to anticoagulation alone. The study involved 100 patients across 22 sites and showed a higher rate of normalization of RV/LV ratio without increased complications. These findings could influence future treatment guidelines for pulmonary embolism.

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PEN
Oct 8, 2025
PENConferences/Events

Penumbra, Inc. Schedules Investor Event at TCT Conference on October 26, 2025; Earnings Release and Conference Call for Third Quarter 2025 Scheduled for November 5, 2025

Penumbra, Inc. will host an investor event on October 26, 2025, at the TCT Conference, focusing on the STORM-PE clinical trial. A conference call for third quarter financial results is scheduled for November 5, 2025. The events will be accessible via webcast, emphasizing the company's commitment to transparency and investor engagement.

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PEN
Aug 27, 2025
PENGeneral

Penumbra, Inc. Names Shruthi Narayan as Company President

Penumbra, Inc. has announced the promotion of Shruthi Narayan to President, effective September 1, 2025. Narayan, a seasoned leader with 20 years in the medical device industry, previously led the company's interventional business. Her appointment is expected to drive continued growth and innovation in Penumbra's life-saving technologies.

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PEN
Aug 20, 2025
PENConferences/Events

Penumbra, Inc. to Present at Upcoming Investor Conferences

Penumbra, Inc. has announced its participation in two upcoming investor conferences: the Wells Fargo Healthcare Conference on September 3, 2025, and the Morgan Stanley 23rd Annual Global Healthcare Conference on September 9, 2025. The presentations will be accessible via webcasts on the company's website for at least two weeks after each event. Penumbra is known for its advancements in thrombectomy technologies.

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About Penumbra, Inc.

Alameda, CA 4,700 employees penumbrainc.com
HeadquartersONE PENUMBRA PLACE, ALAMEDA, CA, 94502
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