Approval Probability
TA Base Rate
Adjusted LOA
ML Risk
Also known as Drug: Apixaban sprinkle capsules, Drug: Apixaban sprinkle
Apixaban sprinkle · 1 trial · 1 indication
Assessment of bioavailability of apixaban 0.5mg tablets relative to apixaban 0.1mg Sprinkle in terms of concentration
Assessment of bioavailability of apixaban 0.5mg tablets relative to apixaban 0.1mg Sprinkle in terms of plasma concentration and time
Assessment of bioavailability of apixaban 0.5mg tablets relative to apixaban 0.1mg Sprinkle in terms of plasma concentration and time
| Arm | Type | Description |
|---|---|---|
| Apixaban sprinkle capsules followed by apixaban tablets | EXPERIMENTAL | Apixaban (BMS-562247) sprinkle capsules followed by apixaban tablets |
| Apixaban tablets followed by apixaban sprinkle capsules | ACTIVE_COMPARATOR | Apixaban (BMS-562247) tablets followed by apixaban sprinkle capsules |
| Name | Type | Description |
|---|---|---|
| Drug: Apixaban sprinkle capsules | DRUG | Single dose (25 x 0.1 mg capsules), oral administration |
| Experimental: Apixaban tablets followed by apixaban sprinkle capsules | DRUG | Apixaban sprinkle capsules Single dose (25 x 0.1 mg capsules), oral administration |
Inclusion Criteria: * Signed informed consent form. * Healthy male and female participants determined by no clinically significant deviation from normal in medical history, physical examination, 12-lead ECGs (electrocardiograms), vital signs and clinical laboratory determinations. * Women of childb...