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Loteprednol Etabonate

Phase 1

Eye Pain | Small molecule | Ophthalmology |Bausch Health Companies Inc.|Last Updated: Feb 24, 2017

Success Probability

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Market & Valuation

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Trial Design

UNCONTROLLEDDMC
Total Trials1
Total Enrollment15

FDA Designations

No designations recorded

Clinical trial landscape

Loteprednol Etabonate · 1 trial · 1 indication

Phase 1 1
NCT03063489Evaluation of the Safety, Systemic Pharmacokinetics, and TolerabilityEye Pain
COMPLETED15 Analytics
PHASE1COMPLETED
Evaluation of the Safety, Systemic Pharmacokinetics, and Tolerability
Eye PainUnlock trial analytics

Study Endpoints

Primary Endpoints

Blood samples will be collected for the determination of loteprednol etabonate concentrations in plasma samples
2 weeks
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Study Design & Arms

AllocationNA
MaskingNONE
ModelSINGLE_GROUP
PurposeSUPPORTIVE_CARE

Treatment Arms

ArmTypeDescription
Loteprednol Etabonate Ophthalmic GelEXPERIMENTALFormulated LE into a gel (loteprednol etabonate ophthalmic gel, \[Lotemax® gel\])

Interventions

NameTypeDescription
Loteprednol Etabonate Ophthalmic GelDRUGFormulated LE into a gel (loteprednol etabonate ophthalmic gel, \[Lotemax® gel\])
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Eligibility Criteria

Age Range18 Years to N/A
SexALL
Healthy VolunteersYes
Study Sites6

Key Inclusion Criteria: * Are able to read, understand and provide written informed consent on an Informed Consent Form (ICF) approved by the Institutional Review Board (IRB)/Independent Ethics Committee (IEC). * Be a non-smoking male or female at least 18 years of age on the date the ICF is signed...

Countries:United States
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Frequently asked questions about Loteprednol Etabonate

What is Loteprednol Etabonate used for?

Loteprednol Etabonate is an investigational small molecule being studied for the treatment of eye pain. It is in Phase 1 clinical development for this indication. The drug is being evaluated in the ophthalmology therapeutic area.

Who makes Loteprednol Etabonate?

Loteprednol Etabonate is being developed by Bausch Health Companies Inc. (NYSE: BHC). The company is conducting clinical research on this drug for the treatment of eye pain.

What phase is Loteprednol Etabonate in?

Loteprednol Etabonate is in Phase 1 clinical development. It is an investigational drug and has not been approved by regulatory authorities. One Phase 1 trial has been completed.

What clinical trials is Loteprednol Etabonate in?

Loteprednol Etabonate has one completed clinical trial, NCT03063489, titled "Evaluation of the Safety, Systemic Pharmacokinetics, and Tolerability." This Phase 1 study enrolled 15 participants in the United States and included healthy volunteers.

Is Loteprednol Etabonate FDA approved?

Loteprednol Etabonate is not FDA approved. It is an investigational drug currently in Phase 1 clinical development for eye pain. The completed trial evaluated safety, pharmacokinetics, and tolerability in healthy volunteers.