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Cabtreo

Phase 1

Acne | Small molecule | Dermatology |Bausch Health Companies Inc.|Last Updated: Dec 24, 2025

Success Probability

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Market & Valuation

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Trial Design

RandomizedCONTROLLED
Total Trials1
Total Enrollment72

FDA Designations

No designations recorded

Clinical trial landscape

Cabtreo · 1 trial · 1 indication

Early Phase 1 1
NCT05582434Experience With Topical Acne TreatmentAcne
ACTIVE NOT_RECRUITING72 Analytics
EARLY_PHASE1ACTIVE NOT_RECRUITING
Experience With Topical Acne Treatment
AcneUnlock trial analytics

Study Endpoints

Primary Endpoints

Medication Adherence
End of study visit - day 56

Medication adherence measured by recording the weight of medication (in milligrams) in the bottle with electronic monitor attached

Secondary Endpoints

Gender specific adherence (female subjects)
End of study visit - day 56
Gender specific adherence (male subjects)
End of study visit - day 56
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Study Design & Arms

AllocationRANDOMIZED
MaskingNONE
ModelPARALLEL
PurposeTREATMENT

Treatment Arms

ArmTypeDescription
One single fixed-combination productEXPERIMENTALParticipants instructed to apply clindamycin phosphate 1.2%/adapalene 0.15%/BPO 3.1% gel once daily
Two productsEXPERIMENTALParticipants instructed to apply 0.3%/BPO 2.5% gel and compounded clindamycin phosphate 1.2% gel once daily
Three productsEXPERIMENTALParticipants instructed to apply BPO 2.5% gel, adapalene 0.1% gel, and compounded clindamycin phosphate 1.2% gel once daily

Interventions

NameTypeDescription
clindamycin phosphate 1.2%/adapalene 0.15%/BPO 3.1% gelDRUGSingle topical treatment to be applied daily to area affected once daily.
adapalene 0.3%/BPO 2.5% gel and compounded clindamycin phosphate 1.2% gelDRUGTwo topical treatments to be applied to area affected once daily.
Compounded BPO 2.5% gel, adapalene 0.1% gel, and compounded clindamycin phosphate 1.2% gelDRUGThree topical treatments to be applied to area affected once daily.
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Eligibility Criteria

Age Range18 Years to 85 Years
SexALL
Healthy VolunteersNo
Study Sites1

Inclusion Criteria: 1. Adult patients ≥18 years of age 2. Patients with a current diagnosis of acne 3. Patients who live in the US, 4. Patients have sufficient command of the English language Exclusion Criteria: 1. Patients less than the age of 18 2. Patients without a current diagnosis of acne 3...

Countries:United States
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