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Beam Therapeutics Inc.

BEAM
Richly ValuedBiotech · Clinical
FDA catalysts, PDUFA dates & pipeline intelligence
$25.7
▲ +1.15 · +4.66%

Financials

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52W LOW $20.2352W HIGH $38.26
Volume
1.80 M
Value Traded
34.27 M
Short % Float
27.18%
+0.12%Week
+5.46%1 Month
-17.1%3 Month
-14.84%6 Month
-60.78%5 Year
+19.33%All Time

Cash Data

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  • Burn Trend
  • Dilution Risk
  • SEC Filing

Key Stats

Market Cap
2.65 B
EPS (TTM)
-3.39
P/E Ratio
-
Ent. Value
1.60 B
Total Shares
103.25 M
Float Shares
95.23 M
Insiders
7.81%
Institutions
97.68%

Upcoming Catalysts

FDA decisions, readouts and PDUFA dates · scored by probability of approval

Catalyst Drug / Treatment Stage Prob. of Approval Description Drug Type Therapeutic Area Source
Phase 1/2 data readout
BEAM-301
Glycogen storage disease type Ia (GSDIa)
Phase 1/2Gene TherapiesRare Diseases
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Every FDA decision, readout and PDUFA date, with drug type, therapeutic area and a PoA score you can trade on.
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PoA blends historical approval base rates, trial design score and FDA review track record.

BEAM Catalyst Timeline

Dated clinical, regulatory and corporate events for Beam Therapeutics Inc.

Catalyst Timeline

Dated clinical, regulatory & corporate events for Beam Therapeutics Inc.

284Total events
6Upcoming
42Tier-1 (high impact)
2020 to 2029Coverage

Upcoming catalysts 2

T1BLA Submission
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risto-cel
T1Topline Readout
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PM647

Event history 50

▲Oral PresentationBEAM-302FiledPresentation
Updated Phase 1/2 data for BEAM-302 presented at ERS Congress 2026
Alpha-1 Antitrypsin Deficiency (AATD)source ↗
▲Full ResultsBEAM-302FiledClinical Data
Updated Phase 1/2 clinical data for BEAM-302 in AATD presented at ERS Congress 2026
Alpha-1 Antitrypsin Deficiency (AATD)source ↗
▲Long Term DataBEAM-302FiledClinical Data
Up to 18 months follow-up data showing durability of in vivo correction with BEAM-302
Alpha-1 Antitrypsin Deficiency (AATD)source ↗
●Management ChangeCorporate
Eric Foster appointed Chief Commercial Officer
▲First Patient DosedBEAM-302FiledTrial
First patient dosed in global pivotal cohort of BEAM-302 trial
Alpha-1 Antitrypsin Deficiency (AATD)source ↗
▲Enrollment Completeristo-celTrial
Dosing complete for all adult and adolescent patients in Phase 1/2 BEACON trial of Risto-cel
Sickle Cell Diseasesource ↗
▲IP Litigation RulingPM647IP / Competition
Arbitration tribunal declares PM647 within Prime Medicine's Field, no damages owed to Beam
Alpha-1 Antitrypsin Deficiency (AATD)source ↗
◆IND SubmissionPM647IND
IND and/or CTA filing for PM647 expected in Q3 2026
Alpha-1 Antitrypsin Deficiency (AATD)source ↗
◆Oral PresentationBEAM-302FiledPresentation
Presentation at ATS International Conference 2026 featuring BEAM-302 clinical data
alpha-1 antitrypsin deficiency (AATD)source ↗
●Quarterly UpdateCorporate
First quarter 2026 financial results reported
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Past FDA Catalysts and PDUFA Decisions

How BEAM actually traded into and out of each decision

Date Drug Catalyst Stage Reaction Event Move % Best Trade %
2026-09-30PM647 IND Submission IND
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Reaction: 30 trading days around the event · Event Move: close to close on decision day · Best Trade: peak run-up from entry 10 days before the decision

Drug Pipeline Intelligence

C45 / 100
Pipeline Score
$263M
Pipeline Value
Richly Valued
Valuation Signal
5
Drugs Scored
0.1x
rNPV / MCap
Top 27%
Small Cap
(rank 179 of 660)
Percentile Rank
Beam Therapeutics Inc. carries a moderate pipeline score (45/100), with $405M risk-adjusted pipeline value, led by BEAM-302 in Alpha 1-Antitrypsin Deficiency (Phase 1).
Showing 1 of 5 assets
DrugIndicationPhasePTRSrNPVStatusEnrollVelocityDesignEst. CompletionML SignalLast Change
BEAM-302 Small moleculeNCT06389877Alpha 1-Antitrypsin DeficiencyPhase 1 RECRUITING 192May 1, 2030
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Clinical Trial Results

Readouts, endpoints and source filings for every BEAM program

Drug Name Indication Phase Date Trial Results SummaryTitleSource
BEAM-302
RMATOrphan
Alpha-1 Antitrypsin Deficiency (AATD)Phase 1/22026-09-08sustained AAT protein production under normal physiological control with follow-up extending up to 18 monthsRead MoreBeam Therapeutics Presents Updated Clinical Data from the Phase 1/2 Trial of BEAM-302 in Alpha-1 Antitrypsin Deficiency (AATD) at the European Respiratory Society (ERS) Congress 2026Read More
Scroll for more · summaries link to the source press release
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Inside Trades

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Monthly insider buys and sells against the stock price, with the insider sentiment reading.
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InsiderSideSharesPriceValueDate
Cavanagh Bethany JOfficer (SVP, Finance and Treasurer)Sell -187 50,984 held$24.41 10/01/2026
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Hedge Fund 13F Activity

Fund % of Portfolio Current MV Shares Owned Activity
Kynam Capital Management, LP 5.4 % 97.50 M 2.84 M -22.85% ( -841.39 K)
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Shares held by hedge funds each quarter, and who bought or sold.

BEAM Institutional Ownership Trends

Options Data

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OI 30-day avg
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Option Volume
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Option Chain Statistics

ExpiryCall VolPut VolVol P/CCall OIPut OIOI P/CIV CallIV Call OI-WtdIV Call Vol-WtdIV PutIV Put OI-WtdIV Put Vol-Wtd
2026-10-16
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Real-Time Option Chain

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Calls vs Puts by Expiry

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Competitive positioning

How BEAM ranks across every disease it competes in

Competitive Position is a premium feature
See how BEAM ranks against every competitor across each disease it develops in: phase, best drug, trials and likelihood of approval.
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BEAM News

BEAM
Sep 8, 2026
BEAMPhases
▼ -9.5%on this news

Beam Therapeutics Presents Updated Clinical Data from the Phase 1/2 Trial of BEAM-302 in Alpha-1 Antitrypsin Deficiency (AATD) at the European Respiratory Society (ERS) Congress 2026

Beam Therapeutics presented updated clinical data for BEAM-302 at the ERS Congress 2026. The trial indicates that BEAM-302 may serve as a one-time treatment for Alpha-1 Antitrypsin Deficiency (AATD), effectively addressing both lung and liver manifestations. Data show sustained AAT protein production under normal physiological control with follow-up extending up to 18 months.

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BEAM
Sep 1, 2026
BEAMGeneral

Beam Therapeutics Appoints Eric Foster as Chief Commercial Officer

Beam Therapeutics has appointed Eric Foster as its Chief Commercial Officer. Foster will oversee the company's commercial strategy as it prepares for the potential launch of its product candidate, risto-cel, in 2027. With over 25 years of experience in biotechnology, Foster's leadership is expected to enhance Beam's commercial capabilities and support multiple product launches.

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BEAM
Aug 31, 2026
BEAMConferences/Events

Beam Therapeutics to Participate in Upcoming September 2026 Investor Conferences

Beam Therapeutics Inc. has announced its participation in several investor conferences, including fireside chats. This engagement reflects the company's commitment to connecting with the investment community and discussing its innovations in precision genetic medicines through base editing. The events are set to take place in September 2026.

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BEAM
Aug 4, 2026
BEAMPhases
▲ +9.4%on this news

Beam Therapeutics Reports Second Quarter 2026 Financial Results and Announces First Patient Dosed in Global Pivotal Cohort of BEAM-302 Trial in Alpha-1 Antitrypsin Deficiency (AATD)

Beam Therapeutics has reported its financial results for the second quarter of 2026, highlighting a successful dosing of the first patient in the global pivotal cohort of the BEAM-302 trial for Alpha-1 Antitrypsin Deficiency. Additionally, the updated Phase 1/2 clinical data has been selected for a late-breaking oral presentation at the European Respiratory Society Congress. The company also completed dosing for all patients in the BEACON trial of Risto-cel in Sickle Cell Disease.

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BEAM
Jul 23, 2026
BEAMConferences/Events

Beam Therapeutics to Present Updated Data from Phase 1/2 Trial of BEAM-302 in Alpha-1 Antitrypsin Deficiency (AATD) in Late-Breaking Oral Presentation at the European Respiratory Society (ERS) Congress 2026

Beam Therapeutics is set to present updated data from its Phase 1/2 trial of BEAM-302, targeting Alpha-1 Antitrypsin Deficiency (AATD). The presentation will occur at the European Respiratory Society (ERS) Congress in 2026. Additionally, the company will host an investor webcast to discuss the clinical data on September 8, 2026.

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BEAM
Jun 18, 2026
BEAMFDA Updates
▲ +5.1%on this news

Beam Therapeutics Announces Clearance of Investigational New Drug Application for BEAM-304 for the Treatment of Phenylketonuria (PKU) by the United States (U.S.) Food and Drug Administration

Beam Therapeutics has received FDA clearance for its investigational new drug application for BEAM-304, aimed at treating phenylketonuria (PKU). This innovative program utilizes a platform-based approach to develop multiple mutation-specific base editors. The company plans to initiate a Phase 1/2 trial to establish clinical proof of concept for this therapy. Preclinical data indicates promising results in normalizing plasma phenylalanine levels.

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BEAM
May 18, 2026
BEAMPhases

Beam Therapeutics Presents Recently Reported Topline Clinical Data for BEAM-302 in Alpha-1 Antitrypsin Deficiency (AATD) at the American Thoracic Society (ATS) 2026 International Conference

Beam Therapeutics presented new clinical data for BEAM-302 at the ATS 2026 conference, highlighting its potential to durably restore normal AAT function in patients with alpha-1 antitrypsin deficiency (AATD). The Phase 1/2 trial results indicate significant efficacy and safety, with plans for accelerated FDA approval. The company aims to enroll more patients for further evaluation.

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BEAM
May 13, 2026
BEAMConferences/Events

Beam Therapeutics to Present at 2026 RBC Capital Markets Global Healthcare Conference

Beam Therapeutics Inc. will present at the 2026 RBC Capital Markets Healthcare Conference on May 20, 2026. CEO John Evans is scheduled to speak at 10:30 a.m. ET in New York. The presentation will be available via a live webcast and archived for 60 days. Beam focuses on precision genetic medicines using base editing technology.

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BEAM
May 12, 2026
BEAMPhases

Beam Therapeutics to Present Updated Biomarker Data from Phase 1/2 BEACON Trial Further Underscoring Risto-cel’s Ability to Restore Red Blood Cell Health and Function in Sickle Cell Disease at EHA2026

Beam Therapeutics announced that it will present updated biomarker data from the BEACON Phase 1/2 trial of risto-cel for sickle cell disease at EHA2026. The data indicates risto-cel's potential to improve red blood cell health and function, with results comparable to sickle cell trait. This underscores the therapy's promising profile for patients with severe sickle cell disease.

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BEAM
May 7, 2026
BEAMPhases

Beam Therapeutics Reports First Quarter 2026 Financial Results and Recent Business Updates Recent BEAM-302 Topline Data in Alpha-1 Antitrypsin Deficiency (AATD) Demonstrate Strong Single-dose Safety and Efficacy Profile,

Beam Therapeutics has reported promising first quarter 2026 financial results and advancements in its clinical trials. The topline data for BEAM-302 in alpha-1 antitrypsin deficiency indicates a strong safety and efficacy profile, with plans to initiate a pivotal cohort later this year. Additionally, the company anticipates filing a Biologics License Application for risto-cel in sickle cell disease by year-end 2026. Beam's financial resources are robust, with $1.2 billion in cash, ensuring operational stability through mid-2029.

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BEAM
Feb 24, 2026
BEAMPhases
▲ +14%on this news

Beam Therapeutics Reports Fourth Quarter and Year-End 2025 Financial Results and Announces New Liver-Targeted Genetic Disease Program in Phenylketonuria (PKU)

Beam Therapeutics has reported its financial results for Q4 and year-end 2025 while announcing the introduction of BEAM-304, a new program targeting phenylketonuria (PKU). This program aims to utilize advanced base editing technology to correct mutations associated with PKU, offering potential long-term solutions for patients. Additionally, Beam's financial strategy includes a significant non-dilutive capital investment to support its development efforts, including a Biologics License Application for risto-cel expected by the end of 2026. The company is well-positioned for clinical and regulatory milestones over the next few years.

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BEAM
Jan 11, 2026
BEAMFDA Updates
▲ +22.3%on this news

Beam Therapeutics Sets Strategic Priorities for its Genetic Disease and Hematology Franchises to Drive Execution of Late-Stage Clinical Programs and Extends its Operating Runway through Commercial Transition

Beam Therapeutics announced its strategic priorities for 2026, focusing on its liver-targeted genetic disease and hematology programs. The company has aligned with the FDA on a potential accelerated approval pathway for BEAM-302, targeting Alpha-1 Antitrypsin Deficiency, and plans to submit a Biologics License Application for its risto-cel therapy by late 2026. Beam's strong financial position with $1.25 billion in cash is expected to support operations and facilitate the progress of its clinical programs through 2029. The company continues to innovate in the field of precision genetic medicines, showcasing advancements in their ongoing trials and pipeline development.

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BEAM
Nov 4, 2025
BEAMPhases
▼ -6.2%on this news

Beam Therapeutics Reports Third Quarter 2025 Financial Results and Recent Business Updates

Beam Therapeutics has reported its third-quarter 2025 financial results, highlighting continued progress in its clinical trials, including BEAM-302 and BEAM-101. The company has a robust cash position of $1.1 billion, expected to fund operations until 2028, amidst ongoing research efforts in alpha-1 antitrypsin deficiency and sickle cell disease. Additionally, Beam is involved in a strategic acquisition scenario with Orbital Therapeutics, potentially enhancing its market position, but faces challenges with ongoing financial losses and rising R&D expenditures. Updated data presentations are scheduled for upcoming industry events, signaling active engagement in the biotech field.

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BEAM
Aug 5, 2025
BEAMPhases

Beam Therapeutics Reports Second Quarter 2025 Financial Results and Provides Update on BEAM-302 Development Progress in Alpha-1 Antitrypsin Deficiency (AATD)

Beam Therapeutics released its second quarter 2025 financial results, highlighting significant clinical progress in its BEAM-302 trial for alpha-1 antitrypsin deficiency (AATD) with 17 patients dosed. The company reported durable correction of the disease-causing mutation and emphasized a well-tolerated safety profile. Beam also indicated cash reserves to sustain operations through 2028, with upcoming data expected from BEAM-302 and BEAM-101 clinical trials by early and late 2025 respectively. Additionally, BEAM-302 has received RMAT and orphan drug designations from the FDA, underscoring its potential for AATD treatment.

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BEAM
May 6, 2025
BEAMPhases
▼ -19.3%on this news

Beam Therapeutics Reports First Quarter 2025 Financial Results and Recent Business Highlights First Patient Dosed in the Phase 1/2 Study of BEAM-301 in Glycogen Storage Disease Type Ia, Beam's Second Clinical Stage In Vivo Editing Program

Beam Therapeutics reported its first quarter 2025 financial results, highlighting significant clinical advancements and a solid financial position. The company announced the dosing of the first patient in the Phase 1/2 study of BEAM-301 for glycogen storage disease type Ia and continued progress in its BEAM-302 program for alpha-1 antitrypsin deficiency. Financially, Beam ended the quarter with $1.2 billion in cash and equivalents, supported by a recent $500 million financing. Additionally, updates on other clinical programs are anticipated in 2025, presenting opportunities for further advancements.

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BEAM
Mar 10, 2025
BEAMGeneral
▼ -9.8%on this news

Beam Therapeutics Announces Pricing of Underwritten Offering

Beam Therapeutics announced the pricing of an underwritten offering of over 16 million shares priced at $28.48 each, projected to raise about $500 million. The proceeds will be aimed at advancing their base editing technology and funding various clinical trials, such as for alpha-1 antitrypsin deficiency and sickle cell disease. The offering is expected to finalize on March 11, 2025, subject to standard closing conditions. Major financial institutions, including J.P. Morgan and Citigroup, are managing the offering.

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BEAM
Mar 10, 2025
BEAMPhases
▼ -9.8%on this news

Beam Therapeutics Announces Positive Initial Data for BEAM-302 in the Phase 1/2 Trial in Alpha-1 Antitrypsin Deficiency (AATD), Demonstrating First Ever Clinical Genetic Correction of a Disease-causing Mutation

Beam Therapeutics announced promising initial results from their Phase 1/2 trial of BEAM-302 for treating Alpha-1 Antitrypsin Deficiency (AATD). Initial data shows that BEAM-302, after a single dose, can significantly increase levels of functional Alpha-1 Antitrypsin while reducing the levels of harmful mutant proteins. The treatment appears to be well tolerated, with no serious adverse effects reported. Further results are anticipated at a medical conference in late 2025 as the trial continues.

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BEAM
Feb 25, 2025
BEAMPhases

Beam Therapeutics Reports Fourth Quarter and Year-End 2024 Financial Results and Reiterates Anticipated Catalysts

Beam Therapeutics has reported its fourth-quarter and year-end financial results for 2024, achieving its adult enrollment target in the BEACON trial for sickle cell disease therapy BEAM-101. The company is set to present updated data from this trial in mid-2025 while also progressing on other therapies, including BEAM-302 for alpha-1 antitrypsin deficiency. Although the company holds $850.7 million in cash to sustain operations through 2027, it experienced notable net losses and a decrease in cash reserves compared to the previous year. The upcoming milestones and existing cash position indicate a well-structured plan moving forward in 2025.

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BEAM
Dec 31, 2024
BEAMPhases

PRECISION GENETIC MEDICINES THROUGH BASE EDITING NASDAQ: BEAM January 2025 Cautionary note regarding forward-looking statements This presentation contains forward-looking statements within the meaning of the Private Secu

Beam Therapeutics is showcasing its advancements in precision genetic medicines through base editing, highlighting the progress of its pipeline candidates such as BEAM-101, BEAM-302, and others. The company's initiatives aim to provide potential one-time curative therapies for diseases like sickle cell disease and alpha-1 antitrypsin deficiency. While Beam has a robust financial position to support its operations, it acknowledges various risks associated with regulatory approvals and clinical trial timelines. The company is set to present significant data and updates throughout 2025, reflecting its leadership in the gene editing field.

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BEAM
Dec 8, 2024
BEAMPhases

Beam Therapeutics Announces New Data from BEACON Phase 1/2 Clinical Trial of BEAM-101 in Sickle Cell Disease at American Society of Hematology (ASH) Annual Meeting All Seven Patients Treated with BEAM-101 Achieved Hemogl

Beam Therapeutics has announced promising data from the BEACON Phase 1/2 clinical trial of its investigational therapy, BEAM-101, for patients with sickle cell disease. All seven patients in the study experienced a robust increase in fetal hemoglobin and reductions in sickle hemoglobin, without reports of vaso-occlusive crises following treatment. Initial safety results are consistent with existing therapies, and further data are expected to provide insights into the long-term benefits of BEAM-101. Beam plans to present additional findings during the upcoming American Society of Hematology annual meeting.

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About Beam Therapeutics Inc.

Cambridge, MA 540 employees beamtx.com
Headquarters26 LANDSDOWNE STREET, CAMBRIDGE, MA, 02139
Founded2017
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