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Biodexa Pharmaceuticals plc

BDRX
UndervaluedPharma · Clinical
FDA catalysts, PDUFA dates & pipeline intelligence
$0.46
▼ -0.07 · -14.07%

Financials

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52W LOW $0.5152W HIGH $59.40
Volume
156.88 K
Value Traded
37.48 K
Short % Float
-
-25.76%Week
-43.34%1 Month
-81.52%3 Month
-86.3%6 Month
-100%5 Year
-100%All Time

Cash Data

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  • SEC Filing

Key Stats

Market Cap
473.58 K
EPS (TTM)
-103.95
P/E Ratio
-
Ent. Value
-9.82 M
Total Shares
1.03 M
Float Shares
-
Insiders
-
Institutions
1.61%

Upcoming Catalysts

FDA decisions, readouts and PDUFA dates · scored by probability of approval

Catalyst Drug / Treatment Stage Prob. of Approval Description Drug Type Therapeutic Area Source
Phase 2 data readout
MTX230 (eRapa)
Non-muscle Invasive Bladder Cancer (NMIBC)
Phase 2Small MoleculesOncology
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Every FDA decision, readout and PDUFA date, with drug type, therapeutic area and a PoA score you can trade on.
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PoA blends historical approval base rates, trial design score and FDA review track record.

BDRX Catalyst Timeline

Dated clinical, regulatory and corporate events for Biodexa Pharmaceuticals plc

Catalyst Timeline

Dated clinical, regulatory & corporate events for Biodexa Pharmaceuticals plc

451Total events
3Upcoming
99Tier-1 (high impact)
2015 to 2029Coverage

Upcoming catalysts 2

T2Trial Initiation
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MTX240
T2IND Submission
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MTX240

Event history 50

◆Reverse Stock SplitCorporate
Share capital reorganization effective June 18, 2026
◆Quarterly UpdateCorporate
AGM scheduled for June 17, 2026
▲Partnership / LicenseMTX240Corporate
Partnership with Syngene to manufacture MTX240 GMP clinical trial supplies
Gastrointestinal Stromal Tumors (GIST)source ↗
◆Topline ReadouteRapaClinical Data
Topline data expected from NMIBC Phase 2 study
Non-muscle Invasive Bladder Cancer (NMIBC)source ↗
▲Partnership / LicenseeRapaCorporate
Tanner Pharma Group and Biodexa announce strategic partnership for global early access program for eRapa in FAP
familiäre adenomatöse Polyposis (FAP)source ↗
▲Partnership / LicenseeRapaCorporate
Strategic partnership with Tanner Pharma Group for global early access program
Familial Adenomatous Polyposissource ↗
◆Enrollment UpdateeRapaTrial
Over 20% of patients enrolled in Phase 3 Serenta trial
Familial Adenomatous Polyposissource ↗
▲Partnership / LicenseMTX240Corporate
Biodexa licenses MTX240 from Otsuka
gastrointestinal stromal tumors (GIST)source ↗
▲Partnership / LicenseOPB-171775Corporate
Exclusive license of OPB-171775 (MTX240) from Otsuka
gastrointestinal stromal tumours (GIST)source ↗
◆Trial InitiationeRapaTrial
Nine additional European sites to activate
familial adenomatous polyposissource ↗
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Past FDA Catalysts and PDUFA Decisions

How BDRX actually traded into and out of each decision

Date Drug Catalyst Stage Reaction Event Move % Best Trade %
2016-12-31MTX102 Phase 1 data readout Phase 1
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Reaction: 30 trading days around the event · Event Move: close to close on decision day · Best Trade: peak run-up from entry 10 days before the decision

Drug Pipeline Intelligence

D29 / 100
Pipeline Score
$3M
Pipeline Value
Undervalued
Valuation Signal
4
Drugs Scored
5.4x
rNPV / MCap
Top 71%
Micro Cap
(rank 467 of 658)
Percentile Rank
Biodexa Pharmaceuticals plc faces pipeline headwinds (29/100), with $260M risk-adjusted pipeline value, led by Treatment with MTX110 in Medulloblastoma (Phase 1).
Showing 1 of 4 assets
DrugIndicationPhasePTRSrNPVStatusEnrollVelocityDesignEst. CompletionML SignalLast Change
Treatment with MTX110 UnknownCompletedNCT04315064MedulloblastomaPhase 1 COMPLETED 2May 2, 2023
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Clinical Trial Results

Readouts, endpoints and source filings for every BDRX program

Drug Name Indication Phase Date Trial Results SummaryTitleSource
MTX110
Fast Track
recurrent glioblastomaPhase 12024-10-04Overall survival (OS) since start of treatment of 12 months and 13 months for Patients #1 and #2, respectively.; Patient #3 had progression free survival (PFS) of six months and OS thus far of 13 months since start of treatment.; Patient #4 has PFS and OS of 12 months since start of treatment.Read MoreBiodexa Provides Update on Progression Free and Overall Survival in Phase 1 Study of MTX110 in Recurrent GlioblastomaRead More
Scroll for more · summaries link to the source press release
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Inside Trades

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Monthly insider buys and sells against the stock price, with the insider sentiment reading.
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InsiderSideSharesPriceValueDate
John SmithCEOBuy 50,000 150,000 held$45.50 01/10/2026
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Hedge Fund 13F Activity

Fund % of Portfolio Current MV Shares Owned Activity
No hedge fund reported a 13F position in BDRX for Q2 2026.
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Shares held by hedge funds each quarter, and who bought or sold.

BDRX Institutional Ownership Trends

Options Data

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Option Chain Statistics

ExpiryCall VolPut VolVol P/CCall OIPut OIOI P/CIV CallIV Call OI-WtdIV Call Vol-WtdIV PutIV Put OI-WtdIV Put Vol-Wtd
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Real-Time Option Chain

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Calls vs Puts by Expiry

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Competitive positioning

How BDRX ranks across every disease it competes in

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See how BDRX ranks against every competitor across each disease it develops in: phase, best drug, trials and likelihood of approval.
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BDRX News

-BDRX
Sep 15, 2026
BDRXGeneral
▲ +18.8%on this news· ran to -35% by day 3

Biodexa Enters Into Warrant Exercise Transaction for $2.3 Million in Gross Proceeds

Biodexa Pharmaceuticals has entered into a warrant exercise agreement with an accredited investor, generating approximately $2.3 million in gross proceeds. The agreement involves the exercise of existing warrants for American Depositary Shares at an exercise price of $1.05. In return, the investor will receive new warrants for additional shares, enhancing Biodexa's financial resources for its clinical programs.

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-BDRX
Sep 11, 2026
BDRXGeneral
▼ -13.8%on this news· ran to -38% by day 3shared move

Interim results for the six months ended June 30, 2026

Biodexa Pharmaceuticals PLC reported its interim results for the six months ending June 30, 2026, highlighting operational advancements such as the in-licensing of MTX240 and the launch of an Early Access Program for eRapa. Financially, the company faced increased R&D costs and significant cash outflows, raising concerns about its future viability. Despite these challenges, the CEO expressed optimism regarding trial enrollments and the potential of their pipeline.

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-BDRX
Aug 19, 2026
BDRXPhases
▼ -9.4%on this news

Biodexa announces major milestone for its Serenta registrational Phase 3 trial in FAP

Biodexa Pharmaceuticals has announced a significant milestone in its Phase 3 trial for eRapa, having recruited 87 out of the planned 168 subjects. The trial, aimed at treating Familial Adenomatous Polyposis (FAP), is being conducted across 29 clinical sites in the US and Europe. The company plans a futility analysis after 25 Progression Free Survival events.

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-BDRX
Jul 29, 2026
BDRXGeneral

Result of General Meeting

Biodexa Pharmaceuticals PLC announced the successful passing of all four resolutions at its General Meeting. The resolutions include a share reorganization that reduces the number of ordinary shares while maintaining their nominal value. Additionally, the directors have been granted authority to allot ordinary shares on a non-pre-emptive basis. This move supports the company's ongoing development of innovative cancer treatments.

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-BDRX
Jul 29, 2026
BDRXPhases

Biodexa Initiates Support Activities for FAP Patients and Treatment Centers in France

Biodexa Pharmaceuticals has initiated support activities for Familial Adenomatous Polyposis (FAP) patients in France, including a round table meeting in Paris. The company aims to enhance patient outcomes and has made its investigational drug eRapa available through an Early Access Program. A Phase 3 trial for eRapa is planned, supported by a $20 million grant.

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-BDRX
Jun 30, 2026
BDRXGeneral

Result of Annual General Meeting

Biodexa Pharmaceuticals PLC held its Annual General Meeting where ordinary resolutions 1 through 7 passed with significant majorities. However, resolutions 8 and 10 failed, leading to the failure of resolution 11, which was contingent on resolution 8. Despite some setbacks, the company remains focused on developing treatments for gastrointestinal cancers and other diseases.

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-BDRX
Jun 30, 2026
BDRXGeneral

Biodexa Announces Pricing of $3.5 Million Registered Direct Offering & Concurrent Private Placement of Pre-Funded Warrants and Warrants

Biodexa Pharmaceuticals has announced a $3.5 million registered direct offering and concurrent private placement. The offerings include American depositary shares and pre-funded warrants, with proceeds expected to fund development programs and working capital. The offerings are set to close on July 1, 2026, pending shareholder approval.

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-BDRX
Jun 29, 2026
BDRXPhases

Approval from Health Canada to expand Serenta Registrational Phase 3 trial in FAP and Update on Serenta Progress

Biodexa Pharmaceuticals has received approval from Health Canada to expand its Phase 3 Serenta trial for familial adenomatous polyposis (FAP) into Canada. The trial, which is already active in the US and Europe, aims to enroll 168 patients, with 73 enrolled so far. The expansion is expected to enhance enrollment and provide a therapeutic option for FAP patients.

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-BDRX
Jun 17, 2026
BDRXGeneral

Postponement and Re-scheduling of Annual General Meeting

Biodexa Pharmaceuticals PLC has postponed its Annual General Meeting (AGM) originally scheduled for June 17, 2026, due to a lack of quorum. The AGM has been rescheduled for June 30, 2026. Proxies submitted for the original meeting will remain valid for the rescheduled date.

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-BDRX
May 14, 2026
BDRXGeneral
▼ -8.5%on this news

Biodexa issues letter to Shareholders

Biodexa Pharmaceuticals PLC has issued a letter to shareholders detailing proposals for reorganizing the company's share capital at the upcoming Annual General Meeting (AGM). The changes are intended to simplify the existing complex structure of ordinary shares while ensuring that shareholder rights and the number of American Depositary Shares (ADSs) remain unchanged. The AGM will take place on June 17, 2026, where several resolutions, including a reverse stock split and share reclassification, will be proposed. The Board recommends voting in favor of these resolutions to facilitate the capital restructuring.

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-BDRX
Apr 2, 2026
BDRXPhases
▲ +42.2%on this news

Biodexa Announces Partnership with Syngene To Manufacture MTX240 GMP Clinical Trial Supplies

Biodexa Pharmaceuticals has announced a partnership with Syngene International to manufacture GMP clinical trial supplies for its drug MTX240. This collaboration marks the second time Syngene has worked with Biodexa, demonstrating their efficiency and flexibility in production timelines. MTX240 utilizes a novel mechanism of action that could address treatment-resistant gastrointestinal stromal tumors (GIST). Biodexa is planning to file an Investigational New Drug application and begin a Phase 1b/2a trial later this year, which will potentially benefit GIST patients who have exhausted existing treatment options.

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-BDRX
Mar 31, 2026
BDRXGeneral

Tanner Pharma Group und Biodexa starten globales Early-Access-Programm für FAP-Patienten

Tanner Pharma Group and Biodexa Pharmaceuticals have announced a strategic partnership to launch a global Early-Access Program for eRapa, targeting patients with familial adenomatous polyposis (FAP). This program will allow clinicians to prescribe this investigational therapy outside of clinical trials, addressing a significant unmet medical need. The initiative will also generate real-world data to enhance understanding of FAP and patient experiences.

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-BDRX
Mar 31, 2026
BDRXGeneral

Resumen: Tanner Pharma Group y Biodexa lanzan un programa de acceso anticipado global para pacientes de poliposis adenomatosa familiar

Tanner Pharma Group and Biodexa Pharmaceuticals have announced a strategic alliance to provide global access to eRapa for patients with familial adenomatous polyposis (FAP). This initiative aims to address the lack of approved therapeutic options for FAP, which typically manifests in adolescence. eRapa, an oral formulation of rapamycin, targets cellular processes involved in tumorigenesis.

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-BDRX
Mar 31, 2026
BDRXGeneral

Riassunto: Tanner Pharma Group e Biodexa lanciano il programma globale di accesso anticipato per i pazienti affetti da FAP

Tanner Pharma Group and Biodexa Pharmaceuticals have partnered to launch a global access program for eRapa, aimed at patients with familial adenomatous polyposis (FAP). This condition, characterized by polyp proliferation in the colon and rectum, currently lacks an approved therapeutic option. eRapa, an oral formulation of sirolimus, targets mTOR pathways involved in cell growth and proliferation.

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-BDRX
Mar 31, 2026
BDRXGeneral

Samenvatting: Tanner Pharma Group en Biodexa lanceren wereldwijd programma voor vroegtijdige toegang voor FAP-patiënten

Tanner Pharma Group and Biodexa Pharmaceuticals have announced a strategic partnership to provide global access to eRapa for patients with familial adenomatous polyposis (FAP). FAP is characterized by excessive polyp growth in the colon and rectum, and currently lacks an approved treatment. eRapa, an oral formulation of rapamycin, may offer a new therapeutic option.

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-BDRX
Mar 27, 2026
BDRXGeneral
▼ -6.5%on this news· ran to +34% by day 3shared move

Preliminary Results for the Year Ended 31 December 2025

Biodexa Pharmaceuticals PLC announced its preliminary results for the year ended December 31, 2025, highlighting the initiation of the Phase 3 Serenta trial for eRapa in Familial Adenomatous Polyposis (FAP). The company also secured a licensing agreement for MTX240 from Otsuka, focusing on gastrointestinal cancers. Despite these advancements, Biodexa reported a loss of £6.38 million and faces challenges in securing further financing.

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-BDRX
Mar 23, 2026
BDRXGeneral

Biodexa Launches Global Early Access Program for eRapa for FAP Patients Through Strategic Partnership with Tanner Pharma Group

Biodexa Pharmaceuticals has partnered with Tanner Pharma Group to launch a Global Early Access Program for eRapa, aimed at patients with Familial Adenomatous Polyposis (FAP). This program allows clinicians to prescribe eRapa outside of clinical trials, addressing a critical need for FAP patients who currently have no approved therapeutic options. Biodexa will also collect Real World Data to enhance understanding of FAP patient challenges.

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-BDRX
Mar 18, 2026
BDRXGeneral
▼ -10.9%on this newsshared move

ADR Ratio Change

Biodexa Pharmaceuticals PLC announced a change in its American Depositary Receipts (ADR) ratio, effective around April 6, 2026. The new ratio will be one ADR for every 500,000 ordinary shares, aimed at meeting Nasdaq's $1.00 minimum bid price requirement. Existing ADR holders will need to exchange their old ADRs for new ones, with no fractional ADRs allocated.

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-BDRX
Mar 9, 2026
BDRXGeneral

Biodexa Announces Support for Life’s a Polyp Foundation First U.S. Patient Advocacy Group for FAP Patients

Biodexa Pharmaceuticals has announced its support for the Life's a Polyp Foundation, the first U.S. advocacy group dedicated to patients with Familial Adenomatous Polyposis (FAP). The foundation aims to empower FAP patients through resources and community support. Biodexa's lead program, eRapa, is currently in a Phase 3 trial, representing a potential non-surgical treatment option for FAP.

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-BDRX
Feb 19, 2026
BDRXPhases

Biodexa Licenses Phase 1 Ready Drug Candidate from Otsuka for Rare Stomach Cancer

Biodexa Pharmaceuticals has licensed MTX240, a Phase 1 ready drug candidate targeting gastrointestinal stromal tumors (GIST). This novel treatment utilizes a unique molecular glue mechanism, potentially benefiting patients with TKI-resistant disease. The company plans to initiate a Phase 1b/2a study by year-end, focusing on high-need populations.

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About Biodexa Pharmaceuticals plc

11 employees biodexapharma.com
HeadquartersCardiff
Founded2000
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