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BridgeBio Pharma, Inc.

BBIOFDA catalysts, PDUFA dates & pipeline intelligence
$70.73
▼ -0.13 · -0.18%

Financials

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52W LOW $60.2252W HIGH $93.42
Volume
4.93 M
Value Traded
249.86 M
Short % Float
11.42%
Days to Cover
7.7
+3.17%Week
+7.49%1 Month
-11.69%3 Month
+3.17%6 Month
+17.55%5 Year
+125.81%All Time

Cash Data

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Key Stats

Market Cap
13.83 B
EPS (TTM)
-3.59
P/E Ratio
-
Ent. Value
14.92 B
Total Shares
195.56 M
Float Shares
175.06 M
Insiders
10.45%
Institutions
91.25%

Upcoming Catalysts

FDA decisions, readouts and PDUFA dates · scored by probability of approval

Catalyst Drug / Treatment Stage Prob. of Approval Description Drug Type Therapeutic Area Source
PDUFA Date
BBP-418 (oral)
limb-girdle muscular dystrophy type 2I/R9 (LGMD2I/R9)
PriorityFast TrackAccelerated+2
PDUFASmall MoleculesRare Diseases
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Every FDA decision, readout and PDUFA date, with drug type, therapeutic area and a PoA score you can trade on.
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PoA blends historical approval base rates, trial design score and FDA review track record.

BBIO Catalyst Timeline

Dated clinical, regulatory and corporate events for BridgeBio Pharma, Inc.

Catalyst Timeline

Dated clinical, regulatory & corporate events for BridgeBio Pharma, Inc.

709Total events
18Upcoming
211Tier-1 (high impact)
2019 to 2027Coverage

Upcoming catalysts 2

T2Product Launch
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BBP-418Filed
T2Product Launch
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EncaleretFiled

Event history 50

▲Oral PresentationEncaleretFiledPresentation
Oral presentation of 24-week CALIBRATE bone turnover data at ASBMR 2026
●Poster PresentationInfigratinibApprovedPresentation
Poster on infigratinib safety data in achondroplasia at ASBMR 2026
achondroplasiasource ↗
●Poster PresentationAcoramidisApprovedPresentation
ATTRibute-CM sTTR to NT-proBNP ratio prognostic measure analysis presented at HFSA ASM 2026
transthyretin amyloid cardiomyopathy (ATTR-CM)source ↗
▲Oral PresentationAcoramidisApprovedPresentation
Real-world EHR comparative effectiveness analysis of acoramidis vs tafamidis presented at HFSA ASM 2026
transthyretin amyloid cardiomyopathy (ATTR-CM)source ↗
▲First Patient DosedEncaleretFiledTrial
First participant dosed in Phase 3 RECLAIM-HP trial of encaleret in chronic hypoparathyroidism
chronic hypoparathyroidismsource ↗
●PublicationAcoramidisApprovedPresentation
ATTRibute-CM sTTR to NT-proBNP ratio analysis published in JACC: Heart Failure
transthyretin amyloid cardiomyopathy (ATTR-CM)source ↗
▲RWE DataAcoramidisApprovedClinical Data
Real-world EHR study shows acoramidis associated with 18% lower risk of composite endpoint vs tafamidis
transthyretin amyloid cardiomyopathy (ATTR-CM)source ↗
●Poster PresentationPresentation
Poster on proband-initiated genetic testing model for ADH1 at ASBMR 2026
▲Subgroup AnalysisAcoramidisApprovedClinical Data
ATTRibute-CM analysis shows acoramidis preserves functional capacity and quality of life in p.Val142Ile variant patients
p.Val142Ile variant transthyretin amyloid cardiomyopathysource ↗
◆Poster PresentationEncaleretFiledPresentation
Baseline symptom burden and impact on daily functioning in ADH1: exit interview findings from Phase 3 CALIBRATE poster at ASBMR 2026
Autosomal Dominant Hypocalcemia Type 1 (ADH1)source ↗
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Past FDA Catalysts and PDUFA Decisions

How BBIO actually traded into and out of each decision

Date Drug Catalyst Stage Reaction Event Move % Best Trade %
2026-10-11encaleret Phase 3 data presentation Phase 3
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Reaction: 30 trading days around the event · Event Move: close to close on decision day · Best Trade: peak run-up from entry 10 days before the decision

Drug Pipeline Intelligence

Pipeline Score
Pipeline Value
Commercial Value
Valuation Signal
9
Drugs Scored
rNPV / MCap
Top Drug
Top 12%
Mid Cap
(rank 80 of 657)
Percentile Rank
Commercial products (revenue basis: trailing 4 quarters of total revenue (10-K and 10-Q), to Jun 2026; product lines: last four quarters to Jun 2026 (10-K and 10-Q))
ProductRevenuePrior periodChange
Attruby
Showing 18 of 20 assets
DrugIndicationPhasePTRSrNPVStatusEnrollVelocityDesignEst. CompletionML SignalLast Change
BBP-418 Small moleculeNCT04800874LGMD2INDA/BLA ACTIVE NOT_RECRUITING 14Nov 1, 2026
BBP-418 Small moleculeNCT05775848Limb-Girdle Muscular Dystrophy Type 2I (LGMD2I)NDA/BLA ACTIVE NOT_RECRUITING 188Jul 1, 2027
Infigratinib Small moleculeNCT07393373HypochondroplasiaPhase 2 ENROLLING BY_INVITATION 159May 31, 2036
BBP-631 Gene therapyNCT04783181Congenital Adrenal HyperplasiaPhase 1 ACTIVE NOT_RECRUITING 8Feb 1, 2029
BBP-812 Gene therapyNCT04998396Canavan DiseasePhase 1 RECRUITING 26Oct 8, 2032
Encaleret Small moleculeNCT07805356HypoparathyroidismPhase 3 RECRUITING 160Jan 1, 2033
Acoramidis Small moleculeMarketedNCT07116473Amyloidosis in Transthyretin (TTR)Phase 3 NOT YET_RECRUITING 250Dec 1, 2037
Acoramidis Small moleculeMarketedNCT04988386Amyloid Cardiomyopathy, Transthyretin-RelatedPhase 3 ACTIVE NOT_RECRUITING 445May 15, 2028
Encaleret Small moleculeNCT05680818Autosomal Dominant Hypocalcemia (ADH)NDA/BLA ACTIVE NOT_RECRUITING 80Aug 1, 2029
Encaleret Small moleculeNCT07080385Autosomal Dominant Hypocalcemia Type 1 (ADH1)NDA/BLA RECRUITING 28Dec 1, 2030
Infigratinib Small moleculeNCT04265651AchondroplasiaNDA/BLA COMPLETED 575Oct 21, 2024
BBP-711 Small moleculeCompletedNCT04876924UndisclosedPhase 1 COMPLETED 92Feb 27, 2022
PORT-77 Small moleculeNCT06971900Erythropoietic Protoporphyria (EPP)Phase 2 COMPLETED 253Nov 24, 2025
ORGN001 Small moleculeCompletedNCT02047461Molybdenum Cofactor Deficiency, Type APhase 2 COMPLETED 13Oct 1, 2022
PTR-01 Small moleculeCompletedNCT03752905Recessive Dystrophic Epidermolysis BullosaPhase 2 COMPLETED 20Nov 30, 2020
Acoramidis Small moleculeMarketedNCT04769479AmyloidosisPhase 3 COMPLETED 1,233Sep 3, 2021
Acoramidis Small moleculeMarketedNCT03458130Familial ATTR-CM (ATTRm-CM, or FAC)Phase 2 COMPLETED 49Oct 5, 2018
ALXN1101 Small moleculeMarketedNCT01894165Molybdenum Cofactor Deficiency (MoCD)Phase 1 COMPLETED 24Sep 1, 2013
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Clinical Trial Results

Readouts, endpoints and source filings for every BBIO program

Drug Name Indication Phase Date Trial Results SummaryTitleSource
Acoramidis ATTR-CM2026-10-1118% lower risk of a composite of death, all-cause hospitalization, new-onset atrial fibrillation, and diuretic intensification versus tafamidis (HR 0.82; 95% CI 0.73-0.93; p<0.01); 27% lower risk of cardiovascular hospitalization; 27% lower risk of heart failure hospitalization; 25% lower risk of all-cause hospitalization; 34% reduction in clinical worsening events versus tafamidis (p=0.046)Read MoreAcoramidis Associated with Significantly Improved Clinical Outcomes Versus Tafamidis in ATTR-CM in an Independent, Real-World Study of U.S. Electronic Health RecordsRead More
Scroll for more · summaries link to the source press release
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Inside Trades

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InsiderSideSharesPriceValueDate
Kumar NeilDirector, Officer (Chief Executive Officer)Sell -8,721 496,965 held$69.01 09/17/2026
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Hedge Fund 13F Activity

Fund % of Portfolio Current MV Shares Owned Activity
Frazier Life Sciences Management, L.P. 2.5 % (-62.1 %) 115.31 M 1.55 M -55.1% ( -1.90 M)
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Shares held by hedge funds each quarter, and who bought or sold.

BBIO Institutional Ownership Trends

BBIO Short Interest

Shares sold short, counted twice a month.

11.42%
Short % of Float
of tradable shares sold short
20.0M
Shares Sold Short
+1.7% vs prior count
7.7 High
Days to Cover
trading days of normal volume to buy every short share back
2.6M
Avg Daily Volume
the average used for days to cover
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Options Data

Option Volume

Open Interest
Call OI
Put OI
Put-Call Ratio
OI 30-day avg
Today vs avg
Option Volume
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Put-Call Ratio
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Option Chain Statistics

ExpiryCall VolPut VolVol P/CCall OIPut OIOI P/CIV CallIV Call OI-WtdIV Call Vol-WtdIV PutIV Put OI-WtdIV Put Vol-Wtd
2026-11-20
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Real-Time Option Chain

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Competitive positioning

How BBIO ranks across every disease it competes in

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See how BBIO ranks against every competitor across each disease it develops in: phase, best drug, trials and likelihood of approval.
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BBIO News

BBIO
Oct 29, 2026
BBIOFDA Updates
▼ -0.2%today

BridgeBio Reports Third Quarter 2026 Financial Results and Corporate Updates

BridgeBio reported $353.2 million in Q3 2026 revenues, driven by Attruby's growth. The company highlighted positive real-world evidence for acoramidis compared to tafamidis. Upcoming PDUFA dates for BBP-418, infigratinib, and encaleret signal potential advancements in treatment options. BridgeBio's cash reserves of $1.5 billion support ongoing and future product launches.

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BBIO
Oct 22, 2026
BBIOConferences/Events

BridgeBio to Report Third Quarter 2026 Financial Results and Commercial Updates on October 29, 2026 at 4:30 pm ET

BridgeBio Pharma, Inc. will release its third quarter 2026 financial results on October 29, 2026. The company will host a conference call at 4:30 pm ET to discuss these results and provide updates on its programs. A live webcast will be available for interested participants.

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BBIO
Oct 16, 2026
BBIOGeneral

BridgeBio Pharma Reports Inducement Grants under Nasdaq Listing Rule 5635(c)(4)

BridgeBio Pharma has announced the approval of equity grants to 32 new employees, totaling 57,853 shares of common stock. These grants are part of an inducement for new hires in accordance with Nasdaq Listing Rule 5635(c)(4). The shares will vest over time, contingent on continued employment. This initiative reflects BridgeBio's commitment to expanding its workforce to support its mission in developing treatments for genetic conditions.

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BBIO
Oct 11, 2026
BBIOPhases

Acoramidis Associated with Significantly Improved Clinical Outcomes Versus Tafamidis in ATTR-CM in an Independent, Real-World Study of U.S. Electronic Health Records

Acoramidis demonstrated significantly improved clinical outcomes compared to tafamidis in patients with ATTR-CM, according to a real-world study utilizing U.S. electronic health records. The analysis revealed an 18% lower risk of adverse events, including hospitalization and mortality. These results support the use of acoramidis as a preferred treatment option for patients with this condition.

Read more →
BBIO
Oct 11, 2026
BBIOPhases

Encaleret Increased Bone Turnover and Improved Participant-Reported Symptoms in the Phase 3 CALIBRATE Trial in ADH1

BridgeBio Pharma's Phase 3 CALIBRATE trial showed that encaleret significantly improved bone turnover and participant-reported symptoms in patients with autosomal dominant hypocalcemia type 1 (ADH1). The FDA has accepted the New Drug Application for encaleret and granted it Priority Review, with a target action date set for May 8, 2027. Additionally, the first participant has been dosed in the RECLAIM-HP trial for chronic hypoparathyroidism.

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BBIO
Oct 6, 2026
BBIOConferences/Events

BridgeBio to Present New Acoramidis Data, Including Independent Comparative Real-World EHR Data at the HFSA Annual Scientific Meeting 2026

BridgeBio Pharma will present new data on acoramidis at the HFSA Annual Scientific Meeting 2026. The presentations will include one oral presentation, three rapid-fire oral presentations, and six poster presentations focused on the treatment of transthyretin amyloid cardiomyopathy (ATTR-CM). Acoramidis is highlighted as a first-line treatment option, with data supporting its clinical profile and effectiveness.

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BBIO
Oct 6, 2026
BBIOConferences/Events

BridgeBio to Present Additional Evidence from the Phase 3 CALIBRATE Trial of Encaleret in ADH1 at the ASBMR 2026 Annual Meeting

BridgeBio Pharma will present additional findings from the Phase 3 CALIBRATE trial of encaleret for autosomal dominant hypocalcemia type 1 (ADH1) at the ASBMR 2026 Annual Meeting. The presentations will include patient-reported outcomes and bone turnover effects. Additionally, data on genetic testing initiatives and safety profiles in children with achondroplasia will be shared.

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BBIO
Oct 6, 2026
BBIOFDA Updates

BridgeBio Announces FDA Acceptance and Priority Review of NDA for Oral Infigratinib for Children with Achondroplasia

BridgeBio announced that the FDA has accepted its New Drug Application for oral infigratinib, a potential first oral treatment for children with achondroplasia, with a target action date of February 4, 2027. The PROPEL 3 trial demonstrated significant efficacy, including the largest annualized height velocity reported in a Phase 3 study. The company is prepared for a U.S. launch upon approval and plans to submit a Marketing Authorization Application to the EMA.

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BBIO
Oct 5, 2026
BBIOGeneral

BridgeBio and Community Partners Launch Nationwide ATTR-CM Education Effort Ahead of World Amyloidosis Day

BridgeBio Pharma has launched a nationwide education initiative to raise awareness about transthyretin amyloid cardiomyopathy (ATTR-CM), particularly among Black Americans who are at higher risk. The campaign kicks off with a YouTube premiere on October 6, featuring discussions led by notable figures in health and culture. The initiative aims to improve recognition and understanding of ATTR-CM, which is often misdiagnosed or overlooked.

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BBIO
Oct 5, 2026
BBIOPhases

BBP-418 Demonstrates Potential to Be Disease Modifying Therapy, Restoring Cardiac and Disease Markers to Unaffected Levels

BridgeBio Pharma presented promising data on BBP-418 during the Phase 3 FORTIFY trial for LGMD2I/R9. At the 12-month interim analysis, 100% of treated individuals normalized HS troponin I levels, and 54% showed stable or improved left ventricular ejection fraction (LVEF). BBP-418 is under FDA Priority Review with a target action date of November 27, 2026, and may become the first approved therapy for this condition.

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BBIO
Sep 23, 2026
BBIOPhases
▼ -5.1%on this news

Acoramidis Demonstrates Real-World Benefit Versus Tafamidis in ATTR-CM, Reducing Risk of Clinical Worsening

Acoramidis has demonstrated a statistically significant benefit over tafamidis in reducing clinical worsening events in patients with ATTR-CM, according to a recent study. The findings indicate a 34% reduction in composite clinical worsening events and a 43% reduction in diuretic intensification. These results highlight acoramidis's potential as a frontline treatment option. Further studies are planned to validate these findings.

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BBIO
Sep 9, 2026
BBIOPhases

Oral Infigratinib Shows Meaningful Benefits Beyond Growth Within 52 Weeks in Children with Achondroplasia in the Phase 3 PROPEL 3 Trial

The Phase 3 PROPEL 3 trial of oral infigratinib demonstrated meaningful benefits for children with achondroplasia, including stabilization of sleep apnea and reduced ear infections. The treatment showed sustained improvements in growth and body proportionality over three years, with a favorable safety profile. BridgeBio has submitted an NDA to the FDA, anticipating a U.S. launch in mid-2027.

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BBIO
Sep 2, 2026
BBIOConferences/Events

BridgeBio to Present New Data on the Impact of Oral Infigratinib on Medical Complications in Achondroplasia at the Annual ESPE Meeting 2026

BridgeBio Pharma will present new findings on oral infigratinib's effects on achondroplasia at the Annual ESPE Meeting 2026. The late-breaking oral presentation will focus on the results from the PROPEL 3 study, alongside additional posters detailing longer-term data. This research aims to address critical medical complications associated with achondroplasia and hypochondroplasia.

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BBIO
Sep 1, 2026
BBIOConferences/Events

BridgeBio to Participate in September Investor Conferences

BridgeBio Pharma, Inc. announced its participation in several upcoming healthcare investor conferences in September 2026. The management team will engage in fireside chats at notable events, including the Wells Fargo Healthcare Conference and the Morgan Stanley Global Healthcare Conference. Live webcasts of these presentations will be accessible on the company's website.

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BBIO
Aug 31, 2026
BBIOGeneral

BridgeBio Announces Agreement with U.S. Government to Improve Affordability and Access to Critical Medicines for Americans

BridgeBio Pharma has entered a voluntary agreement with the U.S. government to enhance access to its medicines and reduce costs for American patients, particularly those on Medicaid. The agreement aims to maintain innovation in rare disease treatments while ensuring affordability. BridgeBio's Attruby will remain available through Medicare without future pricing mandates, and the company continues to support patients through its ForgingBridges program.

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BBIO
Aug 30, 2026
BBIOPhases

Acoramidis Demonstrates Reversal of Cardiac Structural Disease Progression and Functional Decline and Significantly Increases Days Alive and Free from Hospitalization in ATTR-CM

Acoramidis, a treatment for transthyretin amyloid cardiomyopathy (ATTR-CM), has shown promising results in reversing cardiac disease progression and improving patient outcomes. In a Phase 3 study, patients treated with acoramidis experienced significant increases in days alive and free from hospitalization. The therapy demonstrated long-term efficacy and safety across different genetic subgroups, marking a potential shift in treatment for ATTR-CM.

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BBIO
Aug 26, 2026
BBIOPhases

BridgeBio Announces First Participant Dosed in ASCEND-ATTR, a Phase 3b/4 Study Evaluating the Long-Term Effects of Acoramidis on Disease Regression in ATTR-CM

BridgeBio Pharma has initiated the ASCEND-ATTR study, dosing its first participant to evaluate the long-term effects of acoramidis on cardiac structure and function in patients with ATTR-CM. This Phase 3b/4 study aims to determine if acoramidis can lead to sustained improvements in cardiac health, building on previous positive findings from the ATTRibute-CM CMR substudy. The study will enroll approximately 150 participants and utilize advanced imaging techniques to assess treatment efficacy over 36 months.

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BBIO
Aug 24, 2026
BBIOConferences/Events

BridgeBio to Present New Acoramidis Data from Open-Label Extension Analyses in ATTR-CM at ESC Congress 2026

BridgeBio Pharma will present new data on acoramidis for ATTR-CM at the ESC Congress 2026. The findings highlight acoramidis as a first-line treatment, demonstrating significant clinical benefits. Presentations include results on survival benefits and quality of life improvements, further establishing the drug's efficacy in managing this condition.

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BBIO
Aug 14, 2026
BBIOGeneral

BridgeBio Pharma Announces Pricing of Oversubscribed Secondary Offering that Diversifies its Institutional Shareholder Base

BridgeBio Pharma has announced the pricing of an oversubscribed secondary offering of 5 million shares, which will be sold by KKR Genetic Disorder L.P. The company will not receive any proceeds from this offering, which is set to close on August 17, 2026. This move aims to enhance the quality of its shareholder base.

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About BridgeBio Pharma, Inc.

Palo Alto, CA 839 employees bridgebio.com
Headquarters3160 PORTER DR., PALO ALTO, CA, 94304
Founded2015
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