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Tomudex

Phase 2

Inoperable or Recurrent Rectal Cancer | Small molecule | Oncology |AstraZeneca PLC|Last Updated: Jan 25, 2008

Success Probability

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Market & Valuation

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Trial Design

UNCONTROLLED
Total Trials1
Total Enrollment49

FDA Designations

No designations recorded

Clinical trial landscape

Tomudex · 1 trial · 1 indication

Phase 2 1
NCT00590278A Phase-II Study Of TOMUDEX Plus Radiotherapy In Subject With Inoperable or Recurrent Rectal CancerInoperable or Recurrent Rectal Cancer
COMPLETED49 Analytics
PHASE2COMPLETED
A Phase-II Study Of TOMUDEX Plus Radiotherapy In Subject With Inoperable or Recurrent Rectal Cancer
Inoperable or Recurrent Rectal CancerUnlock trial analytics

Study Endpoints

Primary Endpoints

This study will evaluate the value of TOMUDEX in combination with a 'standard' course of pelvic radiotherapy for inoperable/recurrent rectal cancer, in terms of response rate and increasing the resectability rate
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Study Design & Arms

AllocationNON_RANDOMIZED
MaskingNONE
ModelSINGLE_GROUP
PurposeTREATMENT

Interventions

NameTypeDescription
TomudexDRUG -
RadiotherapyPROCEDURE -
HaematologyPROCEDURE -
BiochemistryPROCEDURE -
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Eligibility Criteria

Age Range18 Years to N/A
SexALL
Healthy VolunteersNo
Study Sites1

Inclusion Criteria: * Confirmed diagnosis of inoperable/recurrent rectal cancer * Age \> 18 years * At least 1 measurable lesion should be present * WHO performance score \< 2 * Life expentancy of at least 12 weeks * Subjects will be considered appropriate to receive systemic chemotherapy and pelvi...

Countries:Turkey (Türkiye)
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Frequently asked questions about Tomudex

What is Tomudex used for in inoperable or recurrent rectal cancer?

Tomudex is a small molecule oncology drug being studied for the treatment of inoperable or recurrent rectal cancer. It is administered in combination with radiotherapy, as evaluated in a Phase 2 clinical trial. The drug is intended for patients with this specific advanced form of rectal cancer.

Who makes Tomudex?

Tomudex is developed by AstraZeneca PLC, a biopharmaceutical company listed on the stock exchange under the ticker AZN. AstraZeneca is responsible for the clinical development of Tomudex for the treatment of inoperable or recurrent rectal cancer.

What phase is Tomudex in?

Tomudex is in Phase 2 clinical development. It is an investigational drug, not yet approved by regulatory authorities. The Phase 2 trial for Tomudex in inoperable or recurrent rectal cancer has been completed, with 49 patients enrolled.

What clinical trials is Tomudex in?

Tomudex has one completed clinical trial, identified as NCT00590278, titled "A Phase-II Study Of TOMUDEX Plus Radiotherapy In Subject With Inoperable or Recurrent Rectal Cancer." This Phase 2 trial enrolled 49 patients in Turkey and included adults aged 18 years and older.

How does Tomudex work?

Tomudex is a small molecule drug used in oncology. Its specific molecular target is not disclosed in the available information, so its mechanism of action is not detailed here. It is being studied in combination with radiotherapy for the treatment of inoperable or recurrent rectal cancer.