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Seloken ZOK/Toprol-XL

Phase 3

Heart Failure, Congestive | Small molecule | Cardiovascular |AstraZeneca PLC|Last Updated: Nov 19, 2010

Success Probability

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Market & Valuation

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Trial Design

RandomizedDouble-BlindUNCONTROLLED
Total Trials1
Total Enrollment300

FDA Designations

No designations recorded

Clinical trial landscape

Seloken ZOK/Toprol-XL · 1 trial · 1 indication

Phase 3 1
NCT00038077Reversal of Ventricular Remodeling With Toprol-XLHeart Failure, Congestive
COMPLETED300 Analytics
PHASE3COMPLETED
Reversal of Ventricular Remodeling With Toprol-XL
Heart Failure, CongestiveUnlock trial analytics

Study Design & Arms

AllocationRANDOMIZED
MaskingDOUBLE
PurposeTREATMENT

Interventions

NameTypeDescription
Seloken ZOK/Toprol-XLDRUG50 mg
PlaceboDRUG -
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Eligibility Criteria

Age Range18 Years to N/A
SexALL
Healthy VolunteersNo
Study Sites44

Inclusion Criteria: * Diagnosis of stable asymptomatic heart failure. * Documented ejection fraction less than 0.40. * Must be able to comply with all study procedures. Exclusion Criteria: * Taken B-blocker therapy for longer than 1 week within 6 months prior to randomization. * Have heart proble...

Countries:United States
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Frequently asked questions about Seloken ZOK/Toprol-XL

What is Seloken ZOK/Toprol-XL used for?

Seloken ZOK/Toprol-XL is used for congestive heart failure. It is a small molecule cardiovascular drug being developed by AstraZeneca PLC. The drug is currently in Phase 3 clinical development for this indication.

What does Seloken ZOK/Toprol-XL target?

Seloken ZOK/Toprol-XL is a small molecule cardiovascular drug. Its specific molecular target has not been disclosed in the available clinical trial information. The drug is being studied for its effects on congestive heart failure.

Who makes Seloken ZOK/Toprol-XL?

Seloken ZOK/Toprol-XL is developed by AstraZeneca PLC, a biopharmaceutical company listed on the stock exchange under the ticker AZN. The company is conducting clinical trials to evaluate the drug for congestive heart failure.

What phase is Seloken ZOK/Toprol-XL in?

Seloken ZOK/Toprol-XL is in Phase 3 clinical development. It is an investigational drug being studied for congestive heart failure and has not been approved by regulatory authorities. One Phase 3 trial has been completed.

What clinical trials is Seloken ZOK/Toprol-XL in?

Seloken ZOK/Toprol-XL has one completed Phase 3 clinical trial, identified as NCT00038077, titled "Reversal of Ventricular Remodeling With Toprol-XL." The trial enrolled 300 participants with congestive heart failure in the United States and was randomized and double-blind.

Is Seloken ZOK/Toprol-XL the same as Toprol-XL?

Yes, Seloken ZOK/Toprol-XL is also known as Toprol-XL. The clinical trial NCT00038077 refers to the drug as Toprol-XL, and it is being studied for congestive heart failure by AstraZeneca PLC.