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IVX-A12

Phase 2

Healthy | Monoclonal antibody | Other |AstraZeneca PLC|Last Updated: Dec 4, 2025

Success Probability

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Market & Valuation

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Trial Design

UNCONTROLLED
Total Trials1
Total Enrollment264

FDA Designations

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Clinical trial landscape

IVX-A12 · 2 trials · 2 indications

Phase 2 2
NCT06481579A Study of IVX-A12 in Adults ParticipantsHealthy Participants
COMPLETED143 Analytics
NCT05903183A Study to Evaluate the Safety and Immunogenicity of IVX-A12 in Participants of 60 to 85 Years of AgeHealthy
COMPLETED264 Analytics
PHASE2COMPLETED
A Study of IVX-A12 in Adults Participants
Healthy ParticipantsUnlock trial analytics
PHASE2COMPLETED
A Study to Evaluate the Safety and Immunogenicity of IVX-A12 in Participants of 60 to 85 Years of Age
HealthyUnlock trial analytics

Study Design & Arms

Interventions

NameTypeDescription
IVX-A12BIOLOGICALIVX-A12 IM injection.
Licensed RSV VaccineBIOLOGICALLicensed RSV Vaccine (AREXVY) IM injection.
PlaceboBIOLOGICALDiluent
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Frequently asked questions about IVX-A12

What is IVX-A12 used for?

IVX-A12 is an investigational monoclonal antibody being studied in healthy participants and healthy adults. It is currently in Phase 2 clinical development, with completed trials evaluating its safety and immunogenicity in adults aged 60 to 85 years and in adult participants.

Who makes IVX-A12?

IVX-A12 is being developed by AstraZeneca PLC, a biopharmaceutical company listed on the stock exchange under the ticker symbol AZN. The company is conducting clinical trials to evaluate the safety and immunogenicity of this investigational monoclonal antibody.

What phase is IVX-A12 in?

IVX-A12 is in Phase 2 clinical development. It is an investigational drug, meaning it has not been approved by regulatory authorities and is still undergoing clinical trials to assess its safety and immunogenicity in healthy participants.

What clinical trials is IVX-A12 in?

IVX-A12 has been studied in two completed Phase 2 trials. The first, NCT05903183, evaluated safety and immunogenicity in 264 participants aged 60 to 85 years. The second, NCT06481579, studied IVX-A12 in 143 adult participants. Both trials enrolled healthy individuals.

Is IVX-A12 a monoclonal antibody?

Yes, IVX-A12 is a monoclonal antibody. It is being developed by AstraZeneca PLC as an investigational therapy for healthy participants, with Phase 2 trials completed to evaluate its safety and immunogenicity.