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AZD5985

Phase 1

Healthy | Small molecule | Other |AstraZeneca PLC|Last Updated: Jun 9, 2009

Success Probability

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Market & Valuation

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Trial Design

RandomizedDouble-BlindCONTROLLED
Total Trials1
Total Enrollment32

FDA Designations

No designations recorded

Clinical trial landscape

AZD5985 · 1 trial · 1 indication

Phase 1 1
NCT00799331Exploratory Study to Assess the Pharmacokinetics of AZD5985Healthy
COMPLETED32 Analytics
PHASE1COMPLETED
Exploratory Study to Assess the Pharmacokinetics of AZD5985
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Study Endpoints

Primary Endpoints

It is the objective of this exploratory study to assess pharmacokinetics of AZD5985 following administration of single increasing doses. The primary variable is plasma concentration of AZD5985.
Frequent sampling occasions during study days
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Study Design & Arms

AllocationRANDOMIZED
MaskingTRIPLE
ModelPARALLEL
PurposeBASIC_SCIENCE

Treatment Arms

ArmTypeDescription
AEXPERIMENTALAZD5985
BEXPERIMENTALplacebo

Interventions

NameTypeDescription
AZD5985DRUGOral suspension. Single oral doses of AZD5985 starting with 4 mg and subsequently with up to 3 dose escalations will be administered not exceeding AstraZeneca pre-defined upper exposure limits.
placeboDRUGOral suspension.
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Eligibility Criteria

Age Range18 Years to 45 Years
SexMALE
Healthy VolunteersYes
Study Sites1

Inclusion Criteria: * Provision of signed, written and dated informed consent prior to any study specific procedures. * Healthy male subjects aged 18 to 45 years (inclusive). * Have a body mass index (BMI) between 19 and 30 kg/m2 and weigh at least 50 kg and no more than 100 kg. * Be non-smoker or ...

Countries:Germany
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Frequently asked questions about AZD5985

What is AZD5985 used for?

AZD5985 is an investigational small molecule being studied in healthy volunteers. It is being evaluated in an exploratory Phase 1 clinical trial to assess its pharmacokinetics, which is how the drug is absorbed, distributed, metabolized, and eliminated by the body. The study is not intended to treat a specific disease.

Who makes AZD5985?

AZD5985 is being developed by AstraZeneca PLC, a multinational pharmaceutical company. AstraZeneca is listed on the stock exchange under the ticker symbol AZN. The company is conducting clinical research on this drug candidate to evaluate its properties in early-stage trials.

What phase is AZD5985 in?

AZD5985 is in Phase 1 clinical development. The drug is investigational and has not been approved by regulatory authorities. It is currently being studied in an early-stage clinical trial to assess its pharmacokinetics in healthy male volunteers. The trial has been completed.

What clinical trials is AZD5985 in?

AZD5985 has one completed clinical trial registered under the identifier NCT00799331. The study, titled "Exploratory Study to Assess the Pharmacokinetics of AZD5985," was a Phase 1 trial conducted in Germany with 32 healthy male participants aged 18 years and older. The trial was randomized, double-blind, and controlled.

Is AZD5985 the same as any other drug?

No alternative names for AZD5985 have been reported. The drug is identified solely by its code name AZD5985 in clinical trial registrations and scientific literature. It is a distinct investigational compound being developed by AstraZeneca.