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AZD2820

Phase 1

Healthy | Small molecule | Other |AstraZeneca PLC|Last Updated: Nov 21, 2011

Success Probability

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Market & Valuation

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Trial Design

RandomizedPLACEBO_CONTROLLED
Total Trials1
Total Enrollment90

FDA Designations

No designations recorded

Clinical trial landscape

AZD2820 · 1 trial · 1 indication

Phase 1 1
NCT01332214To Assess the Safety, Tolerability and Pharmacokinetics of AZD2820 After Single Ascending DosesHealthy
COMPLETED90 Analytics
PHASE1COMPLETED
To Assess the Safety, Tolerability and Pharmacokinetics of AZD2820 After Single Ascending Doses
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Study Endpoints

Primary Endpoints

Safety variables ( Adverse events, Vital signs, ECG, EEG, Regiscan, Safety labs.)
Assessments performed multilpe times from the morning day 1 before dose until day 3. And then once at the follow up after 14-18 days

Secondary Endpoints

To evaluate the pharmacokinetics of AZD2820 and assess the dose proportionality of the pharmacokinetics following single ascending doses of AZD2820 by assessment Cmax, tmax, t1/2 , AUC, CL/F, Ae and CLR.
Blood samples will be taken multiple times from the morning day 1 before dose until day 2
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Study Design & Arms

AllocationRANDOMIZED
MaskingSINGLE
ModelPARALLEL
PurposeBASIC_SCIENCE

Treatment Arms

ArmTypeDescription
AZD2820EXPERIMENTAL -
PlaceboPLACEBO_COMPARATOR -

Interventions

NameTypeDescription
AZD2820DRUGSubcutaneous Injection in abdomen or Thigh
PlaceboDRUGSubcutaneous Injection in abdomen or Thigh
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Eligibility Criteria

Age Range20 Years to 45 Years
SexMALE
Healthy VolunteersYes
Study Sites1

Inclusion Criteria: * Provision of signed and dated, written informed consent prior to any study specific procedures. * Healthy male subjects aged ≥20 - ≤45 years with suitable veins for cannulation or repeated venepuncture. * Male subjects should be willing to use barrier contraception ie, condoms...

Countries:United Kingdom
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Frequently asked questions about AZD2820

What is AZD2820 used for?

AZD2820 is an investigational small molecule being studied in healthy volunteers. It was evaluated in a Phase 1 clinical trial to assess its safety, tolerability, and pharmacokinetics after single ascending doses. The study enrolled 90 healthy male participants in the United Kingdom.

Who makes AZD2820?

AZD2820 is being developed by AstraZeneca PLC, a biopharmaceutical company listed on the stock exchange under the ticker AZN. The company conducted a Phase 1 clinical trial of this investigational small molecule in healthy volunteers.

What phase is AZD2820 in?

AZD2820 is in Phase 1 clinical development. It has completed a Phase 1 trial that assessed safety, tolerability, and pharmacokinetics after single ascending doses in healthy volunteers. The drug is investigational and has not been approved for any use.

What clinical trials is AZD2820 in?

AZD2820 has one completed clinical trial, registered as NCT01332214, titled "To Assess the Safety, Tolerability and Pharmacokinetics of AZD2820 After Single Ascending Doses." This Phase 1 study enrolled 90 healthy male participants aged 20 years and older in the United Kingdom.

Was AZD2820 studied in a placebo-controlled trial?

Yes, AZD2820 was studied in a placebo-controlled Phase 1 clinical trial. The trial was randomized and placebo-controlled, though it was not double-blind. The study enrolled 90 healthy male volunteers and has been completed.