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Autoinjector, Vial and syringe

Phase 1

Healthy Adult Participants | Unknown | Other |Astria Therapeutics, Inc.|Last Updated: Jun 9, 2026

Success Probability

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Market & Valuation

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Trial Design

RandomizedACTIVE_CONTROLLED
Total Trials1
Total Enrollment180

FDA Designations

No designations recorded

Clinical trial landscape

Autoinjector, Vial and syringe · 1 trial · 1 indication

Phase 1 1
NCT07635095A Trial to Compare the Pharmacokinetics of Two Presentations of Navenibart in Healthy ParticipantsHealthy Adult Participants
RECRUITING180 Analytics
PHASE1RECRUITING
A Trial to Compare the Pharmacokinetics of Two Presentations of Navenibart in Healthy Participants
Healthy Adult ParticipantsUnlock trial analytics

Study Endpoints

Primary Endpoints

Maximum concentration (Cmax) following a single dose of subcutaneous navenibart
Up to 84 days post dose

Plasma concentrations are assessed via a validated method and used to estimate PK parameters via noncompartmental analysis.

Area under the concentration versus time curve from time 0 to 84 days (AUC0-84d) following a single dose of subcutaneous navenibart
Up to 84 days post dose

Plasma concentrations are assessed via a validated method and used to estimate PK parameters via noncompartmental analysis.

Secondary Endpoints

Time to reach maximum plasma concentration (Tmax) following a single dose of subcutaneous navenibart
Up to 140 days post dose
Apparent clearance (CL/F) following a single dose of subcutaneous navenibart
Up to 140 days post dose
Apparent volume of distribution during the terminal phase (Vz/F) following a single subcutaneous dose of navenibart
Up to 140 days post dose
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Study Design & Arms

AllocationRANDOMIZED
MaskingNONE
ModelPARALLEL
PurposeOTHER

Treatment Arms

ArmTypeDescription
Navenibart vial and syringeACTIVE_COMPARATOR -
Navenibart autoinjectorEXPERIMENTAL -

Interventions

NameTypeDescription
AutoinjectorCOMBINATION_PRODUCTNavenibart administered subcutaneously via autoinjector
Vial and syringeDRUGNavenibart administered subcutaneously via vial and syringe
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Eligibility Criteria

Age Range18 Years to 55 Years
SexALL
Healthy VolunteersYes
Study Sites3

Key Inclusion Criteria: * Males and females 18 to 55 years of age * In good health, as determined by the Investigator * Written informed consent, including confirmation of willingness to comply with all trial procedures * Body weight between 50 and 100 kg, and body mass index (BMI) between 18 and 3...

Countries:United States
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Recent Changes (Last 90 Days)

LOWJun 9, 2026NCT07635095NEW_TRIAL: changed
LOWJun 9, 2026NCT07635095NEW_TRIAL: changed
LOWJun 9, 2026NCT07635095NEW_TRIAL: changed
LOWJun 9, 2026NCT07635095NEW_TRIAL: changed

Frequently asked questions about Autoinjector, Vial and syringe

What is the Autoinjector, Vial and syringe used for?

The Autoinjector, Vial and syringe is used in a Phase 1 clinical trial to compare the pharmacokinetics of two presentations of Navenibart in healthy adult participants. The study is being conducted in the United States and is currently recruiting participants.

Who makes the Autoinjector, Vial and syringe?

The Autoinjector, Vial and syringe is developed by Astria Therapeutics, Inc., a biopharmaceutical company traded on the NASDAQ under the ticker symbol ATXS. The company is conducting a Phase 1 trial to evaluate the pharmacokinetics of two presentations of Navenibart in healthy participants.

What phase is the Autoinjector, Vial and syringe in?

The Autoinjector, Vial and syringe is in Phase 1 clinical development. It is an investigational product being studied in a single active-controlled trial that is currently recruiting participants. The trial is not yet completed, and the product has not been approved for any use.

What clinical trials is the Autoinjector, Vial and syringe in?

The Autoinjector, Vial and syringe is being evaluated in clinical trial NCT07635095, titled 'A Trial to Compare the Pharmacokinetics of Two Presentations of Navenibart in Healthy Participants.' This Phase 1 study is recruiting 180 healthy adult participants in the United States.

Is the Autoinjector, Vial and syringe the same as Navenibart?

The Autoinjector, Vial and syringe refers to the delivery presentations of Navenibart being compared in a clinical trial. The study NCT07635095 is designed to compare the pharmacokinetics of these two presentations of Navenibart in healthy participants.