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Astria Therapeutics, Inc.

$12.58

+0.1 (+0.8%)

D 35Pipeline Score Overvalued Pharma · Clinical
Market Cap
718.13 M
EPS
-2.15
P/E Ratio
-
Value Trade
40.15 M
SEC Financials
Q3 2025
  • Dilution Risk

    40%
  • Revenue

    706.00 K

  • R&D Expenses

    24.15 M


  • Total Assets

    271.87 M

  • Total Liabilities

    38.61 M

  • Equity

    233.25 M

-1.8 %
Week
-2.56 %
1 Month
-0.08 %
3 Month
89.74 %
6 Month
-23.76 %
5 Year
-98.35 %
All Time
Cash Data
Caution
  • Cash Position

    227.72 M

  • Monthly Burn

    11.37 M

  • Runway

    11.4 mo

  • Burn Trend

    Stable
  • SEC Filing

    Nov 12, 2025
Overview
Volume
3.20 M
52 Week Range
3.56 - 13.29
% held by Insiders
12.34 %
% held by Institutions
79.39 %
Enterprise Value
590.19 M
Total Shares
56.41 M
Short %
9.16 %
Float Shares
45.70 M
Company Description

locked

Upcoming Catalyst
Catalyst Drug/Treatment Stage Probability of Approval Description Drug Type Therapeutic Area Source
navenibart (STAR-0215) hereditary angioedema (HAE)
Phase 3

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Biologics
Rare Diseases
navenibart (STAR-0215) hereditary angioedema (HAE)
Phase 3

Subscribe to access the data.

Biologics
Rare Diseases
navenibart (STAR-0215) hereditary angioedema (HAE)
Phase 3

Subscribe to access the data.

Biologics
Rare Diseases
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Past FDA Catalysts & PDUFA Decisions
Date Drug Catalyst Stage Outcome Reaction Event Move % Best Trade %
2025-03-02
navenibart (STAR-0215)
phase 1b/2 data readout
Phase 1b/2
2025-03-02
navenibart (STAR-0215)
phase 1b/2 data readout
Phase 1b/2
2025-03-02
navenibart (STAR-0215)
phase 1b/2 data readout
Phase 1b/2
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Drug Pipeline Intelligence
D35
Pipeline Score
$196M
Pipeline Value
Overvalued
Valuation Signal
3
Drugs Scored
0.3x
rNPV / MCap
Top 50%
Micro Cap
(rank 462 of 923)
Percentile Rank
Astria Therapeutics, Inc. faces pipeline headwinds (35/100), with $702M risk-adjusted pipeline value, led by navenibart in Hereditary Angioedema (HAE) (Phase 3).
Showing 1 of 1 assets
DrugIndicationPhaseNCT IDPTRSrNPVStatusEnrollmentVelocityDesignCompletionML SignalLast Change
navenibart
Small molecule
Hereditary Angioedema (HAE)Phase 3NCT0684282358% $363M ACTIVE NOT_RECRUITING 302 VERY_FAST B (66) Jun 1, 2027 -MEDIUM
Jun 30, 2026
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Clinical Trial Results
Drug Name Indications Phase Date Trial Results Summary Title Source
STAR-0215
hereditary angioedema
Phase 1a
2022-12-15

well-tolerated at all doses studied; estimated half-life of STAR-0215 up to 110 days; sustained target engagement with plasma kallikrein inhibition for at least three months

Read More

Astria Therapeutics Announces Positive Preliminary Results from the Phase 1a Clinical Trial of STAR-0215 in Healthy Subjects -- Shown Early Proof of Concept of STAR-0215's Profile as a Long-Acting Plasma Kallikrein Inhib

Read More
STAR-0215
hereditary angioedema
Phase 1a
2022-12-15

well-tolerated at all doses studied; estimated half-life of STAR-0215 up to 110 days; sustained target engagement with plasma kallikrein inhibition for at least three months

Read More

Astria Therapeutics Announces Positive Preliminary Results from the Phase 1a Clinical Trial of STAR-0215 in Healthy Subjects -- Shown Early Proof of Concept of STAR-0215's Profile as a Long-Acting Plasma Kallikrein Inhib

Read More
STAR-0215
hereditary angioedema
Phase 1a
2022-12-15

well-tolerated at all doses studied; estimated half-life of STAR-0215 up to 110 days; sustained target engagement with plasma kallikrein inhibition for at least three months

Read More

Astria Therapeutics Announces Positive Preliminary Results from the Phase 1a Clinical Trial of STAR-0215 in Healthy Subjects -- Shown Early Proof of Concept of STAR-0215's Profile as a Long-Acting Plasma Kallikrein Inhib

Read More
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Inside Trades
TREND
CORPORATE INSIDERS BOUGHT SHARES WORTH 1.8M IN THE LAST 3 MONTHS
YEARLY INSIDER TRANSACTIONS
Sector Avg.
INSIDERS
SOLD
INSIDERS
BOUGHT
POSITIVE SENTIMENT Based on 22 Insiders Transactions
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Hedge Funds
TREND
HEDGE FUNDS INCREASED HOLDINGS BY 200.0K SHARES IN THE LAST QUARTER
Shares Held
2040.00B1530.00B1020.00B510.00B0
Q3
2024
Q4
2024
Q1
2025
Q2
2025
HEDGE FUNDS
SOLD
HEDGE FUNDS
BOUGHT
POSITIVE SENTIMENT Based on 27 hedge funds in the last quarter
18 buying (3 new)·9 selling (1 exited)·2 unchanged
Fund Count
60%
Share Volume
25%
Conviction
15%
HedgeFund Name
( 3 )
% of Portfolio Current MV
-
Shares Owned
-
Activity
Avg Price $0

Example Capital Management

2.5 %
15.00 M
250.00 K

Example Capital Management

2.5 %
15.00 M
250.00 K

Example Capital Management

2.5 %
15.00 M
250.00 K
Unlock Hedge Funds table data
ATXS Institutional Ownership Trends
Current Insider %
5.20%
+0.00%
Current Institutional %
62.40%
+0.00%
Total Ownership
67.60%
Insider + Institutional
Data Points
1
1 Ticker(s)
Option Chain Statistics
ExpirationVolumeOpen InterestImplied Volatility CallsImplied Volatility Puts
CallsPutsPut-Call RatioCallsPutsPut-Call RatioIVOiWaIvVWaIvIVOiWaIvVWaIv
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Option Chain
CallsStrikePuts
Last PriceVolumeOpen InterestLast PriceVolumeOpen Interest
No data available
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Open interest
0 600K 1.2M 1.8M Avg OI 1.00 M Open Interest
0 1 2 3 1.1 Put-Call Ratio
Today's Open Interest
1.00 M
Put-Call Ratio
1.1
Put Open Interest
480.00 K
Call Open Interest
520.00 K
Open Interest Avg (30-day)
900,000
Today vs Open Interest Avg (30-day)
11.11%
Option Volume
0 450K 900K 1.4M Avg OV 750.00 K Option Volume
0 1 2 3 0.95 Put-Call Ratio
Today's Volume
750.00 K
Put-Call Ratio
0.95
Put Volume
360.00 K
Call Volume
390.00 K
Volume Avg (30-day)
800,000
Today vs Volume Avg (30-day)
-6.25%
Company News
Competitive Position
How ATXS ranks across every disease it competes in
Competitive Position is a premium feature
See how ATXS ranks against every competitor across each disease it develops in: phase, best drug, trials and likelihood of approval.
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