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argenx SE

ARGX
OvervaluedBiotech · Commercial
FDA catalysts, PDUFA dates & pipeline intelligence
$825.03
▲ +6.4 · +0.78%

Financials

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52W LOW $661.8552W HIGH $1,072.75
Volume
512.25 K
Value Traded
314.65 M
Short % Float
2.09%
-9.62%Week
-16.71%1 Month
-5.85%3 Month
+1.95%6 Month
+197.06%5 Year
+4,405.36%All Time

Cash Data

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Key Stats

Market Cap
51.61 B
EPS (TTM)
21.10
P/E Ratio
39.11
Ent. Value
45.93 B
Total Shares
62.56 M
Float Shares
62.76 M
Insiders
0.19%
Institutions
45.34%

Upcoming Catalysts

FDA decisions, readouts and PDUFA dates · scored by probability of approval

Catalyst Drug / Treatment Stage Prob. of Approval Description Drug Type Therapeutic Area Source
Phase 3 topline data readout
empasiprubart
multifocal motor neuropathy (MMN)
Phase 3BiologicsNervous System
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Every FDA decision, readout and PDUFA date, with drug type, therapeutic area and a PoA score you can trade on.
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PoA blends historical approval base rates, trial design score and FDA review track record.

ARGX Catalyst Timeline

Dated clinical, regulatory and corporate events for argenx SE

Catalyst Timeline

Dated clinical, regulatory & corporate events for argenx SE

758Total events
18Upcoming
242Tier-1 (high impact)
2015 to 2027Coverage

Upcoming catalysts 2

T1Topline Readout
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Empasiprubart
T1Topline Readout
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EfgartigimodApproved

Event history 50

▲Primary Endpoint MetFB102Clinical Data
FB102 met primary endpoint of change in Vh:Cd ratio at day 78 (p=0.0176)
celiac diseasesource ↗
▲Topline ReadoutFB102Clinical Data
Positive topline results from Phase 2 study of FB102 in celiac disease
celiac diseasesource ↗
▼Trial Stopped FutilityEfgartigimodApprovedTrial
argenx discontinues Phase 3 UNITY study of efgartigimod SC in Sjögren's disease for futility
Sjögren's diseasesource ↗
▼Interim AnalysisEfgartigimodApprovedTrial
Interim analysis of Phase 3 UNITY study led to IDMC futility recommendation
Sjögren's diseasesource ↗
▼Trial DiscontinuedEfgartigimodApprovedTrial
Phase 3 UNITY study of efgartigimod SC in Sjögren's disease discontinued
Sjögren's diseasesource ↗
▲Oral PresentationEfgartigimodApprovedPresentation
Efgartigimod in AChR Antibody Negative gMG: Efficacy and Safety Results from ADAPT SERON
Acetylcholine Receptor Antibody Negative Generalized Myasthenia Gravissource ↗
▲Poster PresentationEmpasiprubartPresentation
Phase 2 ARDA+ results showing sustained clinical benefit of empasiprubart in MMN presented at AANEM
Multifocal Motor Neuropathy (MMN)source ↗
▲Poster PresentationEfgartigimodApprovedPresentation
Longitudinal analysis of response as first-line treatment with VYVGART Hytrulo in CIDP presented at AANEM
Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)source ↗
▲Poster PresentationAdimanebartPresentation
Phase 1b digital gait outcomes of adimanebart in DOK7-CMS presented at AANEM
DOK7-Congenital Myasthenic Syndromes (CMS)source ↗
●Poster PresentationPresentation
Understanding the Patient Journey in MMN: Descriptive Insights From the iMMersioN Study
Multifocal Motor Neuropathysource ↗
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Past FDA Catalysts and PDUFA Decisions

How ARGX actually traded into and out of each decision

Date Drug Catalyst Stage Reaction Event Move % Best Trade %
2026-10-02VYVGART (efgartigimod alfa-fcab) Phase 3 data presentation Phase 3
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Reaction: 30 trading days around the event · Event Move: close to close on decision day · Best Trade: peak run-up from entry 10 days before the decision

Drug Pipeline Intelligence

C54 / 100
Pipeline Score
$3.5B
Pipeline Value
$22.4B
Commercial Value
Overvalued
Valuation Signal
15
Drugs Scored
0.1x
rNPV / MCap
Top 11%
Large Pharma
(rank 73 of 657)
Percentile Rank
argenx SE carries a moderate pipeline score (54/100), with $3.5B risk-adjusted pipeline value, led by Empasiprubart in Multifocal Motor Neuropathy (MMN) (Phase 3), across $82B in total addressable markets.
Commercial products (revenue basis: trailing 4 quarters of total revenue (20-F and 6-K), to Jun 2026; product lines: last four quarters to Jun 2026 (20-F and 6-K)) Revenue $5.2B x 4.3 = $22.4B
ProductRevenuePrior periodChange
VYVGART$5.2B--
Showing 1 of 15 assets
DrugIndicationPhasePTRSrNPVStatusEnrollVelocityDesignEst. CompletionML SignalLast Change
Empasiprubart Monoclonal antibodyNCT06920004Chronic Inflammatory Demyelinating PolyneuropathyPhase 3 RECRUITING 378Sep 1, 2030
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Clinical Trial Results

Readouts, endpoints and source filings for every ARGX program

Drug Name Indication Phase Date Trial Results SummaryTitleSource
FB102
Fast Track
Celiac DiseasePhase 22026-10-08p value: 0.0176; number of patients: 126Read Moreargenx Announces Positive Topline Results from Phase 2 Study of FB102 in Celiac DiseaseRead More
Scroll for more · summaries link to the source press release
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Inside Trades

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Monthly insider buys and sells against the stock price, with the insider sentiment reading.
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InsiderSideSharesPriceValueDate
John SmithCEOBuy 50,000 150,000 held$45.50 01/10/2026
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Hedge Fund 13F Activity

Fund % of Portfolio Current MV Shares Owned Activity
Avoro Capital Advisors LLC 8.3 % (15.3 %) 927.77 M 1.00 M
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Shares held by hedge funds each quarter, and who bought or sold.

ARGX Institutional Ownership Trends

Options Data

Option Volume

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Call OI
Put OI
Put-Call Ratio
OI 30-day avg
Today vs avg
Option Volume
Call Vol
Put Vol
Put-Call Ratio
Vol 30-day avg
Today vs avg

Option Chain Statistics

ExpiryCall VolPut VolVol P/CCall OIPut OIOI P/CIV CallIV Call OI-WtdIV Call Vol-WtdIV PutIV Put OI-WtdIV Put Vol-Wtd
2026-11-20
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Real-Time Option Chain

CallsStrikePuts
LastVolOILastVolOI
No data available
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Calls vs Puts by Expiry

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Competitive positioning

How ARGX ranks across every disease it competes in

Competitive Position is a premium feature
See how ARGX ranks against every competitor across each disease it develops in: phase, best drug, trials and likelihood of approval.
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ARGX News

ARGX
Oct 8, 2026
ARGXPhases
▼ -11.8%on this news

argenx Announces Positive Topline Results from Phase 2 Study of FB102 in Celiac Disease

argenx announced positive topline results from a Phase 2 study of FB102, a CD122 inhibitor, in adults with celiac disease. The study met its primary endpoint, showing a significant change in the villus height-to-crypt depth ratio compared to placebo. The safety profile was consistent with prior studies, and argenx plans to advance FB102 into Phase 3 development.

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ARGX
Oct 8, 2026
ARGXPhases
▼ -11.8%on this news

argenx Provides Update on Phase 3 UNITY Study of Efgartigimod SC in Sjögren's Disease

argenx SE has announced the discontinuation of its Phase 3 UNITY study of efgartigimod SC in Sjögren's disease, following a recommendation from an Independent Data Monitoring Committee. The study was halted for futility after an interim analysis indicated it could not meet its primary endpoint. Despite consistent safety profiles, this outcome is a setback for patients awaiting effective treatments.

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ARGX
Sep 29, 2026
ARGXConferences/Events

argenx Presents New Data at AANEM and MGFA Scientific Session Showcasing Earlier and Sustained Treatment in MG and CIDP with VYVGART and Progress Across its Neuromuscular Pipeline

argenx presented new data at the AANEM and MGFA sessions, highlighting VYVGART's effectiveness in treating myasthenia gravis (MG) and chronic inflammatory demyelinating polyneuropathy (CIDP). The data showed significant improvements in ocular MG and sustained efficacy in patients without detectable anti-AChR antibodies. Additionally, real-world evidence indicated that earlier treatment with VYVGART leads to better patient outcomes.

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ARGX
Sep 17, 2026
ARGXGeneral

argenx announces results of Extraordinary General Meeting of Shareholders and appointment of Thomas M. Brakel and Khurem Farooq as Non-Executive Directors

argenx SE announced the results of its Extraordinary General Meeting, appointing Thomas M. Brakel and Khurem Farooq as non-executive directors. The company emphasizes its commitment to scientific innovation and enhancing shareholder value. The appointments are seen as a strategic move to strengthen the Board as argenx aims for long-term growth and impact in immunology.

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ARGX
Sep 2, 2026
ARGXGeneral

BenchSci Announces Two-Year Enterprise Agreement with argenx to Advance AI-Driven Preclinical Drug Discovery

BenchSci has entered into a two-year enterprise agreement with argenx to implement its AI-driven research environment, EMET, for preclinical drug discovery. This collaboration was chosen through a competitive evaluation by argenx's scientists and marks a significant step for BenchSci's expansion in the European biopharma market. The partnership aims to enhance the efficiency of drug discovery processes.

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ARGX
Sep 1, 2026
ARGXConferences/Events

argenx to Present at Upcoming Investor Conferences

argenx announced its participation in two upcoming investor conferences in September 2026. The management team will engage in fireside chats at the Wells Fargo 21st Annual Healthcare Conference and the Morgan Stanley 24th Annual Global Healthcare Conference. Live webcasts of these presentations will be available on the company's website.

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ARGX
Aug 17, 2026
ARGXPhases
▲ +16%on this news

argenx Announces Positive Topline Results from Phase 3 ALKIVIA Trial of Efgartigimod in Autoimmune Myositis

argenx announced positive topline results from the Phase 3 ALKIVIA trial of efgartigimod in patients with autoimmune myositis. The study met its primary endpoint, demonstrating a significant improvement in the Total Improvement Score at 52 weeks. Efgartigimod showed consistent benefits across both IMNM and DM subtypes, marking a significant advancement in treatment options for these patients.

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ARGX
Aug 3, 2026
ARGXGeneral

argenx announces Extraordinary General Meeting of Shareholders on September 17, 2026

argenx SE has announced an Extraordinary General Meeting of Shareholders scheduled for September 17, 2026, in Amsterdam. The meeting will focus on the proposed appointments of two new non-executive directors to the Board. Shareholders are encouraged to attend in person or vote by proxy, with detailed information available on the company's website.

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ARGX
Jul 27, 2026
ARGXGeneral

argenx to Acquire Forte Biosciences, Inc., Adding First-in-Class Anti-CD122 Antibody, FB102, to Its Immunology Pipeline

argenx has announced its acquisition of Forte Biosciences for $77 per share, totaling approximately $2.2 billion. This strategic move aims to enhance argenx's immunology portfolio by adding FB102, a first-in-class anti-CD122 antibody. The acquisition reflects argenx's commitment to expanding its innovative treatment options in immunology.

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ARGX
Jul 23, 2026
ARGXGeneral
▲ +8.6%on this newsshared move

argenx Reports Half Year 2026 Financial Results and Provides Second Quarter Business Update

argenx reported strong financial results for the second quarter of 2026, with $1.5 billion in global product net sales, marking a 60% increase year-over-year. The company successfully launched expanded indications for VYVGART and VYVGART Hytrulo, now covering all gMG serotypes. Key registrational study readouts are expected in the second half of 2026, supporting the company's growth strategy.

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ARGX
Jul 16, 2026
ARGXConferences/Events

argenx to Report Half Year 2026 Financial Results and Second Quarter Business Update on July 23, 2026

argenx has announced a conference call scheduled for July 23, 2026, to discuss its half-year financial results and provide a business update for the second quarter. The call will be accessible via a webcast and various international dial-in numbers. The company focuses on developing treatments for severe autoimmune diseases.

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ARGX
Jul 15, 2026
ARGXGeneral

Chai Discovery Enters Into Collaboration Agreement With argenx to Advance AI-Driven Immunology Breakthroughs

Chai Discovery has entered a collaboration agreement with argenx to utilize its AI platform for antibody discovery. This partnership aims to enhance therapeutic targets through advanced computational design. Argenx, recognized for its robust antibody development capabilities, will integrate Chai's technology to further its immunology innovations.

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ARGX
Jun 23, 2026
ARGXConferences/Events
▼ -5.6%on this news

argenx to Host Autoimmune Myositis R&D Webinar

argenx is hosting a webinar on June 23, 2026, focusing on autoimmune myositis and their advancements in FcRn leadership. The event will feature key opinion leaders from prestigious institutions discussing the latest research and developments. A live webcast will be available, along with supporting materials on their website.

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ARGX
Jun 3, 2026
ARGXConferences/Events

argenx Presents New Efgartigimod Data Showing Long-Term Sustained Patient Benefit in Myositis and Sjogren’s Disease at EULAR 2026

Argenx presented new data on efgartigimod at EULAR 2026, demonstrating its long-term benefits in myositis and Sjogren's disease. The ALKIVIA+ study showed sustained improvements in myositis patients, while the RHO+ study confirmed maintenance of response in Sjogren's disease. Efgartigimod's safety profile remained consistent across various autoimmune conditions.

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ARGX
May 28, 2026
ARGXConferences/Events

argenx to Host Myositis R&D Webinar on June 23, 2026

argenx announced a webinar titled 'R&D Spotlight: Advancing FcRn Leadership into Autoimmune Myositis' scheduled for June 23, 2026. This event is part of a mini-series aimed at showcasing the company's research and development strategy. The webinar will feature discussions on myositis, including disease biology and the ALKIVIA clinical program for efgartigimod.

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ARGX
May 8, 2026
ARGXFDA Updates

argenx Announces U.S. FDA Approval Expanding VYVGART and VYVGART Hytrulo for Use in All Adult Patients Living with gMG

argenx announced that the FDA has approved a label expansion for VYVGART and VYVGART Hytrulo, allowing their use in all adult patients with generalized myasthenia gravis (gMG), including those without detectable anti-AChR antibodies. This approval is based on the Phase 3 ADAPT SERON study, which demonstrated significant symptom improvements in patients treated with VYVGART. The expansion aims to meet the needs of a broader range of gMG patients, simplifying treatment decisions for clinicians.

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ARGX
May 7, 2026
ARGXGeneral

argenx Reports First Quarter 2026 Financial Results and Provides Business Update

argenx SE reported a robust first quarter for 2026, achieving $1.3 billion in global product net sales, marking a 63% increase year-over-year. The company is optimistic about the upcoming PDUFA date for anti-AChR antibody negative gMG on May 10, 2026, and is advancing its pipeline with several candidates expected to enter registrational studies. argenx aims to treat 50,000 patients globally by 2030 and is expanding its leadership in FcRn therapies.

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ARGX
May 7, 2026
ARGXGeneral

argenx Announces Results of Annual General Meeting and Board of Directors’ Appointment of Karen Massey as Chief Executive Officer

argenx SE has announced the appointment of Karen Massey as Chief Executive Officer, succeeding Tim Van Hauwermeiren, who will now serve as Chairperson of the Board. The transition follows a successful Annual General Meeting where shareholders approved all agenda items. Massey, who joined the company in March 2023, is expected to lead the next phase of growth for argenx.

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ARGX
May 6, 2026
ARGXConferences/Events

argenx to Present at BofA Securities 2026 Health Care Conference

argenx announced that CEO Karen Massey will present at the BofA Securities 2026 Health Care Conference on May 12, 2026. The presentation will focus on the company's advancements in treating severe autoimmune diseases. A live webcast will be available, along with a replay for 30 days post-event.

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About argenx SE

1,863 employees argenx.com
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