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Amgen Inc.

AMGNFDA catalysts, PDUFA dates & pipeline intelligence
$465.45
▼ -0.56 · -0.12%

Financials

Last updated
Revenue
R&D Expenses
Operating CF
Total Assets
Total Liabilities
Equity
Shares Out.
D/E Ratio
Quarterly Cash
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52W LOW $292.1252W HIGH $475.64
Volume
3.20 M
Value Traded
1.49 B
Short % Float
2.48%
Days to Cover
5.0
+3.91%Week
+15.5%1 Month
+19.34%3 Month
+41.22%6 Month
+33.74%5 Year
+98,606.32%All Time

Cash Data

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Key Stats

Market Cap
251.64 B
EPS (TTM)
16.17
P/E Ratio
28.78
Ent. Value
300.40 B
Total Shares
540.63 M
Float Shares
539.40 M
Insiders
0.23%
Institutions
85.69%

Upcoming Catalysts

FDA decisions, readouts and PDUFA dates · scored by probability of approval

Catalyst Drug / Treatment Stage Prob. of Approval Description Drug Type Therapeutic Area Source
Phase 3 data presentation
UPLIZNA (inebilizumab-cdon)
IgG4-related disease
Phase 3BiologicsRare Diseases
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Every FDA decision, readout and PDUFA date, with drug type, therapeutic area and a PoA score you can trade on.
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PoA blends historical approval base rates, trial design score and FDA review track record.

AMGN Catalyst Timeline

Dated clinical, regulatory and corporate events for Amgen Inc.

Catalyst Timeline

Dated clinical, regulatory & corporate events for Amgen Inc.

2438Total events
19Upcoming
971Tier-1 (high impact)
2010 to 2036Coverage

Upcoming catalysts 2

T2Quarterly Update
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T3Poster Presentation
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InebilizumabApproved

Event history 50

▲Partnership / LicenseCorporate
NORD and Amgen launch 14-month Learning Collaborative pilot across Rare Disease Centers of Excellence
IgG4-Related Disease (IgG4-RD) and Thyroid Eye Disease (TED)source ↗
●R&D DayPresentation
Amgen virtual investor event on oncology portfolio and ESMO 2026 data
▲Topline ReadoutIMDELLTRAApprovedClinical Data
Interim Phase 3 DeLLphi-305 results: IMDELLTRA + IMFINZI reduced risk of death by 58% in 1L maintenance ES-SCLC
extensive stage small cell lung cancer (ES-SCLC)source ↗
▲Long Term DataIMDELLTRAApprovedClinical Data
DeLLphi-303 updated data: median OS 37.9 months in 1L maintenance with IMDELLTRA plus anti-PD-L1
extensive stage small cell lung cancer (ES-SCLC)source ↗
▲PublicationIMDELLTRAApprovedPresentation
DeLLphi-305 results simultaneously published in The New England Journal of Medicine
extensive stage small cell lung cancer (ES-SCLC)source ↗
▲Late-BreakerIMDELLTRAApprovedPresentation
DeLLphi-305 presented as late-breaker (LBA3) in ESMO 2026 Presidential Symposium
extensive stage small cell lung cancer (ES-SCLC)source ↗
▲Primary Endpoint MetIMDELLTRAApprovedClinical Data
DeLLphi-305 met primary OS endpoint with 58% reduction in risk of death
extensive stage small cell lung cancer (ES-SCLC)source ↗
▲Poster PresentationIMDELLTRAApprovedPresentation
DeLLphi-303 updated OS data presented as poster (3821P) at ESMO 2026
extensive stage small cell lung cancer (ES-SCLC)source ↗
▲Oral PresentationIMDELLTRAApprovedPresentation
DeLLphi-304 updated data presented as oral (3808O) at ESMO 2026
previously treated extensive stage small cell lung cancer (ES-SCLC)source ↗
▲Full ResultsTEZSPIREApprovedClinical Data
Full CROSSING Phase 3 results in EoE announced
eosinophilic esophagitis (EoE)source ↗
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Every PDUFA date, readout, approval and corporate move, tiered by market impact and updated daily.
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Past FDA Catalysts and PDUFA Decisions

How AMGN actually traded into and out of each decision

Date Drug Catalyst Stage Reaction Event Move % Best Trade %
2026-10-24tarlatamab-dlle (IMDELLTRA) plus durvalumab (IMFINZI) Phase 3 data presentation Phase 3
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Reaction: 30 trading days around the event · Event Move: close to close on decision day · Best Trade: peak run-up from entry 10 days before the decision

Drug Pipeline Intelligence

Pipeline Score
Pipeline Value
Commercial Value
Valuation Signal
37
Drugs Scored
rNPV / MCap
Top Drug
Top 1%
Large Pharma
(rank 1 of 674)
Percentile Rank
Commercial products (revenue basis: trailing 4 quarters of total revenue (10-K and 10-Q), to Jun 2026; product lines: last four quarters to Jun 2026 (10-K and 10-Q))
ProductRevenuePrior periodChange
Prolia
Repatha
EVENITY
Otezla
TEPEZZA
ENBREL
XGEVA
BLINCYTO
Nplate
TEZSPIRE
KRYSTEXXA
KYPROLIS
Top 12 of 14 product lines shown.
Showing 95 of 538 assets
DrugIndicationPhasePTRSrNPVStatusEnrollVelocityDesignEst. CompletionML SignalLast Change
Maridebart cafraglutide Small moleculeNCT07226765Obstructive Sleep ApneaPhase 3 ACTIVE NOT_RECRUITING 250Sep 13, 2028
Maridebart cafraglutide Small moleculeNCT07160257Type 2 Diabetes MellitusPhase 3 ACTIVE NOT_RECRUITING 1,765Mar 4, 2027
Maridebart cafraglutide Small moleculeNCT06858878Type 2 Diabetes Mellitus (T2DM), Obesity, OverweightPhase 3 ACTIVE NOT_RECRUITING 1,105Apr 16, 2027
Maridebart cafraglutide Small moleculeNCT06987695Obesity DiseasePhase 3 ACTIVE NOT_RECRUITING 279Jul 21, 2027
Maridebart cafraglutide Small moleculeNCT06858839ObesityPhase 3 ACTIVE NOT_RECRUITING 9,205Apr 16, 2027
Maridebart cafraglutide Small moleculeNCT07575399Obesity or OverweightPhase 3 RECRUITING 300Feb 28, 2028
Maridebart cafraglutide Small moleculeNCT07037459Heart Failure With Preserved Ejection FractionPhase 3 RECRUITING 5,056Sep 29, 2030
Maridebart cafraglutide Small moleculeNCT07037433Atherosclerotic Cardiovascular DiseasePhase 3 ACTIVE NOT_RECRUITING 12,800Sep 29, 2030
Maridebart cafraglutide Small moleculeNCT07441252Overweight or Obesity and Elevated Liver FatPhase 2 ACTIVE NOT_RECRUITING 180Nov 17, 2027
Maridebart cafraglutide Small moleculeNCT07523711OverweightPhase 1 ACTIVE NOT_RECRUITING 818Nov 18, 2026
Tarlatamab Monoclonal antibodyMarketedNCT05361395Extensive Stage Small Cell Lung CancerApproved ACTIVE NOT_RECRUITING 1,379May 30, 2030
Tarlatamab Monoclonal antibodyMarketedNCT06898957Small Cell Lung CancerApproved ACTIVE NOT_RECRUITING 1,723Jun 23, 2031
Tarlatamab Monoclonal antibodyNCT06117774Limited Stage Small Cell Lung CancerPhase 3 ACTIVE NOT_RECRUITING 834Apr 20, 2030
Tarlatamab Monoclonal antibodyMarketedNCT07423585Extensive Stage Lung Small Cell CarcinomaApproved RECRUITING 39Dec 31, 2027
Tarlatamab Monoclonal antibodyMarketedNCT05060016Relapsed/Refractory Small Cell Lung CancerApproved ACTIVE NOT_RECRUITING 222Dec 30, 2027
Tarlatamab Monoclonal antibodyMarketedNCT03319940Small Cell Lung CarcinomaApproved ACTIVE NOT_RECRUITING 269Dec 31, 2027
Olpasiran RNA therapyNCT05581303Atherosclerotic Cardiovascular DiseasePhase 3 ACTIVE NOT_RECRUITING 7,297Mar 31, 2028
ABP 692 Small moleculeNCT06700343Relapsing-remitting Multiple Sclerosis (RRMS)Phase 3 ACTIVE NOT_RECRUITING 152Oct 4, 2027
ABP 234 Small moleculeNCT06311721Advanced or Metastatic Non-squamous Non-Small Cell Lung CancerPhase 3 ACTIVE NOT_RECRUITING 315Apr 24, 2028
ABP 234 Small moleculeNCT06430866Early-stage Non-squamous Non-small Cell Lung Cancer (NSCLC)Phase 3 ACTIVE NOT_RECRUITING 163Dec 14, 2026
AMG 127 Small moleculeNCT07590193Diabetes Mellitus, Type 2Phase 1 RECRUITING 162Oct 2, 2027
ABP 206 Small moleculeNCT06054555MelanomaPhase 3 ACTIVE NOT_RECRUITING 889Jan 25, 2028
AMG 691 Small moleculeNCT06637371AsthmaPhase 1 ACTIVE NOT_RECRUITING 21Apr 10, 2027
Inebilizumab Monoclonal antibodyNCT07598825Autoimmune HepatitisPhase 3 RECRUITING 180Feb 11, 2034
Inebilizumab Monoclonal antibodyNCT04540497IgG4 Related DiseasePhase 3 ACTIVE NOT_RECRUITING 135Oct 31, 2028
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PTRS, rNPV, enrollment velocity, trial design quality and ML risk signals for every asset above.
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Clinical Trial Results

Readouts, endpoints and source filings for every AMGN program

Drug Name Indication Phase Date Trial Results SummaryTitleSource
dazodalibep Sjögren's diseasePhase 32026-10-27ESSDAI score change 4w: -5.6; ESSDAI score change 12w: -5.2; ESSDAI score change placebo: -3.8; ESSPRI dryness score change: -2.50; ESSPRI dryness score change placebo: -1.33; DASPRI dryness score change: -1.98; DASPRI dryness score change placebo: -1.05Read MoreAMGEN TO PRESENT NEW DATA ACROSS RARE AND OTHER SERIOUS AUTOIMMUNE DISEASES AT ACR CONVERGENCE 2026Read More
Scroll for more · summaries link to the source press release
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Inside Trades

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Monthly insider buys and sells against the stock price, with the insider sentiment reading.
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InsiderSideSharesPriceValueDate
Khosla RachnaOfficer (SVP, Business Development)Option 1,252 7,656 held$162.60 08/13/2026
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Hedge Fund 13F Activity

Fund % of Portfolio Current MV Shares Owned Activity
ORBIMED ADVISORS LLC 0.3 % 14.04 M 39.90 K -9.73% ( -4.30 K)
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Every 13F position with quarter over quarter share flow and average entry price.
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Shares held by hedge funds each quarter, and who bought or sold.

Ownership Trends

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Insider and institutional ownership, quarter by quarter.

AMGN Short Interest

Shares sold short, counted twice a month.

2.48%
Short % of Float
of tradable shares sold short
13.4M
Shares Sold Short
-4.6% vs prior count
5.0 Moderate
Days to Cover
trading days of normal volume to buy every short share back
2.7M
Avg Daily Volume
the average used for days to cover
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Two years of days to cover and shares sold short, with every count and its change.
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Options Data

Option Volume

Open Interest
Call OI
Put OI
Put-Call Ratio
OI 30-day avg
Today vs avg
Option Volume
Call Vol
Put Vol
Put-Call Ratio
Vol 30-day avg
Today vs avg

Option Chain Statistics

ExpiryCall VolPut VolVol P/CCall OIPut OIOI P/CIV CallIV Call OI-WtdIV Call Vol-WtdIV PutIV Put OI-WtdIV Put Vol-Wtd
2026-11-06
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Per-expiry call and put volume, open interest, put-call ratios and implied volatility.
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Real-Time Option Chain

CallsStrikePuts
LastVolOILastVolOI
No data available
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Calls vs Puts by Expiry

CallsPutsLog scale
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Competitive positioning

How AMGN ranks across every disease it competes in

Competitive Position is a premium feature
See how AMGN ranks against every competitor across each disease it develops in: phase, best drug, trials and likelihood of approval.
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AMGN News

AMGN
Oct 28, 2026
AMGNConferences/Events

AMGEN ANNOUNCES WEBCAST OF 2026 THIRD QUARTER FINANCIAL RESULTS

Amgen will announce its third quarter 2026 financial results on November 3, 2026. Following the announcement, a conference call will take place at 4:30 p.m. ET, featuring CEO Robert A. Bradway and senior management. The call will be broadcast live and available for replay on Amgen's website.

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AMGN
Oct 27, 2026
AMGNGeneral

AMGEN ANNOUNCES 2026 FOURTH QUARTER DIVIDEND

Amgen announced a quarterly dividend of $2.52 per share for Q4 2026. This dividend will be paid on December 11, 2026, to stockholders of record as of November 20, 2026. The company continues to be recognized for its innovation in the biotechnology sector.

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AMGN
Oct 27, 2026
AMGNConferences/Events

AMGEN TO PRESENT NEW DATA ACROSS RARE AND OTHER SERIOUS AUTOIMMUNE DISEASES AT ACR CONVERGENCE 2026

Amgen announced it will present new data on autoimmune diseases at ACR Convergence 2026. Key findings include significant improvements in systemic disease activity and dryness in Sjögren's disease patients treated with dazodalibep. Additionally, long-term data for UPLIZNA in IgG4-related disease will be shared, highlighting Amgen's dedication to rare diseases.

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AMGN
Oct 27, 2026
AMGNGeneral

NORD and Amgen Launch Learning Collaborative to Improve Rare Disease Diagnosis and Care

NORD and Amgen have launched a Learning Collaborative to enhance the diagnosis and care of rare autoimmune diseases, specifically IgG4-Related Disease and Thyroid Eye Disease. This 14-month pilot program will involve 5 to 8 institutions working together to identify and address challenges in care coordination and diagnosis. The initiative aims to generate insights applicable to other rare diseases as well.

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AMGN
Oct 26, 2026
AMGNGeneral

AMGEN APPOINTS DAVID W. GIBBS TO BOARD OF DIRECTORS

Amgen appointed David W. Gibbs to its Board of Directors, effective immediately. Gibbs, former CEO of Yum! Brands, will serve on the Audit and Compensation Committees. His leadership experience and expertise in customer relations are expected to benefit Amgen's future product launches and innovations.

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AMGN
Oct 24, 2026
AMGNPhases

IMDELLTRA® IN COMBINATION WITH IMFINZI® REDUCED RISK OF DEATH BY AN UNPRECEDENTED 58% IN FIRST-LINE EXTENSIVE STAGE SMALL CELL LUNG CANCER

Amgen announced that IMDELLTRA combined with IMFINZI significantly reduced the risk of death by 58% in extensive stage small cell lung cancer patients. Nearly 80% of patients were alive at one year, compared to 53% with IMFINZI alone. The median overall survival reached 21.1 months, marking a substantial improvement in treatment outcomes. These results were presented at the ESMO Congress 2026.

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AMGN
Oct 22, 2026
AMGNGeneral

AMGEN FOUNDATION TOPS $75 MILLION IN HANDS-ON BIOTECHNOLOGY EDUCATION, REACHING 100,000 STUDENTS A YEAR

The Amgen Foundation announced a $13.4 million commitment to the Amgen Biotech Experience, extending the program through the 2027-28 school year. This initiative provides biotechnology education to over 100,000 students annually, with a total of 1.25 million students served since its inception. The program aims to enhance STEM education in schools, particularly those facing resource challenges.

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AMGN
Oct 20, 2026
AMGNConferences/Events

AMGEN TO PRESENT AT THE EUROPEAN SOCIETY OF MEDICAL ONCOLOGY CONGRESS 2026

Amgen will host a webcast on October 24, 2026, during the ESMO 2026 Congress. Executives Murdo Gordon and Jean-Charles Soria will discuss the oncology portfolio and selected data. The event is open to investors and media. It will be archived for 30 days.

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AMGN
Oct 20, 2026
AMGNPhases

TEZSPIRE® DELIVERED HISTOLOGIC REMISSION AND SYMPTOM IMPROVEMENT IN EOSINOPHILIC ESOPHAGITIS

Amgen and AstraZeneca announced positive results from the Phase 3 CROSSING trial for TEZSPIRE in treating eosinophilic esophagitis (EoE). The trial demonstrated significant improvements in histologic remission and symptom severity at both 24 and 52 weeks. TEZSPIRE achieved remission in 64.8% to 68.9% of patients, outperforming placebo significantly. These findings suggest TEZSPIRE could be an important new treatment option for patients with uncontrolled EoE.

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AMGN
Sep 22, 2026
AMGNPhases

AMGEN ANNOUNCES POSITIVE TOPLINE PHASE 3 RESULTS FOR DAZODALIBEP IN MODERATE-TO-SEVERE SYSTEMIC SJÖGREN'S DISEASE

Amgen announced positive topline results from the Phase 3 OASIZ 301 study of dazodalibep for moderate-to-severe Sjögren's disease. The study met its primary endpoint, showing significant improvement in systemic disease activity at Week 48. This marks a potential breakthrough for patients, as there are currently no FDA-approved treatments for this debilitating autoimmune disease.

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AMGN
Sep 14, 2026
AMGNFDA Updates

FDA APPROVES REDUCED MONITORING TIME FOR FIRST TWO DOSES OF IMDELLTRA®

Amgen announced that the FDA has approved a significant reduction in the monitoring time required for the first two doses of IMDELLTRA (tarlatamab-dlle) from 22-24 hours to 6-8 hours. This change aims to enhance patient access to treatment for extensive-stage small cell lung cancer by allowing for less time spent in healthcare settings. Follow-up assessments will still be conducted the day after each of the initial doses.

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AMGN
Sep 9, 2026
AMGNConferences/Events

AMGEN TO PRESENT AT THE MORGAN STANLEY 24TH ANNUAL GLOBAL HEALTHCARE CONFERENCE

Amgen will present at the Morgan Stanley 24th Annual Global Healthcare Conference on September 15, 2026. Key executives, including Jay Bradner and Thomas Dittrich, will discuss the company's developments. The presentation will be available via webcast for the public and investors, with an archive accessible for 90 days post-event.

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AMGN
Sep 8, 2026
AMGNPhases
▼ -10.1%on this newsshared move

IMDELLTRA® IN COMBINATION WITH IMFINZI® DEMONSTRATED LANDMARK IMPROVEMENT IN OVERALL SURVIVAL IN FIRST-LINE EXTENSIVE STAGE SMALL CELL LUNG CANCER

Amgen announced that its Phase 3 DeLLphi-305 study met its primary endpoint. The trial showed a statistically significant improvement in overall survival for patients with extensive stage small cell lung cancer. IMDELLTRA combined with durvalumab outperformed durvalumab alone as a first-line maintenance treatment. The drug also improved progression-free survival and objective response rates in the study.

Read more →
AMGN
Sep 2, 2026
AMGNConferences/Events

AMGEN TO PRESENT AT THE 2026 WELLS FARGO HEALTHCARE CONFERENCE

Amgen will present at the 2026 Wells Fargo Healthcare Conference on September 10, 2026. Key executives, including the CFO and CMO, will participate in the presentation. The event will be available via a live webcast, allowing media and investors to access the information. The webcast will also be archived for later viewing.

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AMGN
Aug 31, 2026
AMGNPhases

AMGEN'S REPATHA® REDUCES RISK OF DEATH IN PATIENTS AT HIGH RISK FOR A FIRST HEART ATTACK OR STROKE

Amgen announced that Repatha (evolocumab) significantly reduces the risk of death in high-risk adults without prior cardiovascular events, as shown in the Phase 3 VESALIUS-CV trial. The study, which involved over 12,000 patients, demonstrated a 20% reduction in overall mortality. These findings highlight the importance of early and intensive LDL-C lowering in preventing cardiovascular morbidity and mortality.

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AMGN
Aug 27, 2026
AMGNPhases

TEZSPIRE® DEMONSTRATES POSITIVE PHASE 3 RESULTS IN EOSINOPHILIC ESOPHAGITIS ACROSS BOTH CO-PRIMARY AND ALL KEY SECONDARY ENDPOINTS

Amgen and AstraZeneca announced positive Phase 3 results for TEZSPIRE in treating eosinophilic esophagitis. The drug met its co-primary endpoints for histologic remission and dysphagia improvement at week 24. These benefits remained sustained through week 52 in the CROSSING trial. The safety profile was consistent with previous indications for the treatment.

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AMGN
Aug 4, 2026
AMGNGeneral

AMGEN REPORTS SECOND QUARTER 2026 FINANCIAL RESULTS

Amgen reported strong financial results for Q2 2026, with total revenues rising 10% to $10.1 billion, driven by significant growth in key products. GAAP EPS increased 65% to $4.37, reflecting higher revenues. However, some products, like Prolia, experienced declines in sales, indicating challenges in certain segments. The company remains optimistic about future growth prospects, particularly with ongoing Phase 3 trials.

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AMGN
Jul 31, 2026
AMGNGeneral

FIRST AMGEN SCHOLARS PROGRAM IN INDIA LAUNCHES AT IIIT HYDERABAD

Amgen has launched its first Scholars Program in India at IIIT Hyderabad, aimed at inspiring future scientific innovators. The program will support 10 undergraduate scholars from various countries, focusing on AI and machine learning applications in healthcare and drug discovery. This initiative reflects Amgen's commitment to advancing science education and fostering collaboration in the region.

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AMGN
Jul 30, 2026
AMGNGeneral

AMGEN ANNOUNCES 2026 THIRD QUARTER DIVIDEND

Amgen announced a dividend of $2.52 per share for the third quarter of 2026, payable on September 11, 2026. This dividend reflects the company's strong financial position and commitment to returning value to shareholders. The announcement highlights Amgen's ongoing innovation in biotechnology and its significant role in the industry.

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About Amgen Inc.

Thousand Oaks, CA 31,500 employees amgen.com
HeadquartersONE AMGEN CENTER DRIVE, THOUSAND OAKS, CA, 91320
Founded1980
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