Bacterin to Report First Quarter 2015 Financial Results on

Bacterin to Report First Quarter 2015 Financial

Results on May 5, 2015

BELGRADE, MT, April 23, 2015 --

Bacterin International Holdings, Inc. (OTCQX: BONE), a leader in the development of revolutionary bone graft material, today announced

that it will release its financial results for the period ended March 31, 2015, on May 5, 2015 at the close of the financial markets.

An accompanying conference call will be hosted

by Dan Goldberger, Chief Executive Officer, and John Gandolfo, Chief Financial Officer, to discuss the results. The call will be

held at 10:00 a.m. ET, on May 6, 2015. Please refer to the information below for conference call dial-in information and webcast

Conference date: May

6, 2015, 10:00 AM ET

Conference dial-in: 877-269-7756

International dial-in: 201-689-7817

Conference Call Name: Bacterin's First Quarter 2015 Results Call

Webcast Registration: Click Here (Update)

Following the live call, a replay

will be available on the Company's website, www.bacterin.com,

under "Investor Info".

About Bacterin International Holdings

Bacterin International Holdings, Inc. (OTCQX:

BONE) develops, manufactures and markets biologics products to domestic and international markets. These products are used in a

variety of applications including enhancing fusion in spine surgery, relief of back pain, promotion of bone growth in foot and

ankle surgery, promotion of cranial healing following neurosurgery and subchondral repair in knee and other joint surgeries.

For further information, please

visit www.bacterin.com.

Important Cautions Regarding Forward-looking

This news release contains certain disclosures

that may be deemed forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995 that are

subject to significant risks and uncertainties. Forward-looking statements include statements that are predictive in nature, that

depend upon or refer to future events or conditions, or that include words such as "continue," "efforts," "expects,"

"anticipates," "intends," "plans," "believes," "estimates," "projects,"

"forecasts," "strategy," "will," "goal," "target," "prospects," "potential,"

"optimistic," "confident," "likely," "probable" or similar expressions or the negative

thereof. Statements of historical fact also may be deemed to be forward-looking statements. We caution that these statements by

their nature involve risks and uncertainties, and actual results may differ materially depending on a variety of important factors,

including, among others: the ability of the Company's sales force to achieve expected results, the Company's ability to meet its

existing and anticipated contractual obligations, including financial covenant and other obligations contained in the Company's

secured lending facility; the Company's ability to manage cash flow; the Company's ability to obtain shareholder approval of financing

transactions; the Company's ability to develop, market, sell and distribute desirable applications, products and services and to

protect its intellectual property; the ability of the Company's customers to pay and the timeliness of such payments; the Company's

ability to obtain financing as and when needed; changes in consumer demands and preferences; the Company's ability to attract and

retain management and employees with appropriate skills and expertise; the Company's ability to successfully conclude government

investigations; the impact of changes in market, legal and regulatory conditions and in the applicable business environment, including

actions of competitors; and other factors. Additional risk factors are listed in the Company's Annual Report on Form 10-K and Quarterly

Reports on Form 10-Q under the heading "Risk Factors." The Company undertakes no obligation to release publicly any revisions

to any forward-looking statements to reflect events or circumstances after the date hereof or to reflect the occurrence of unanticipated

events, except as required by law.