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Menlo Therapeutics Announces Completion of Corporate Name Change to VYNE Therapeutics Will commence trading under new Nasdaq Ticker "VYNE"

Key Takeaway: Therapeutics Announces Completion of Corporate Name Change to VYNE Therapeutics Will commence trading under new Nasdaq Ticker "VYNE", September 8, 2020 Company to ring Nasdaq Closing Bell at 4pm Bridgewater, NJ - September 8, 2020 - VYNE Therapeutics Inc. (Nasdaq: VYNE) ("VY

Full Press Release Details

Therapeutics Announces Completion of Corporate Name Change to VYNE Therapeutics
Will commence trading under new Nasdaq Ticker
"VYNE", September 8, 2020
Company to ring Nasdaq Closing Bell at 4pm
Bridgewater, NJ - September 8, 2020 - VYNE
Therapeutics Inc. (Nasdaq: VYNE) ("VYNE" or the "Company") today completed its previously announced corporate
name change from Menlo Therapeutics Inc. to VYNE Therapeutics Inc. and the change of its ticker symbol from "MNLO"
to "VYNE". The name and ticker symbol changes are effective as of the opening of trading today, September 8, 2020.
In celebration of the corporate name change, David Domzalski,
President and Chief Executive Officer, together with other members of the Company, will ring the Nasdaq Closing Bell today
at 4:00 pm ET. Remarks will begin at approximately 3:50 pm ET. The ceremony will take place virtually and a live stream will be
are excited to launch our new corporate identity as VYNE Therapeutics today, and are honored to be marking this important milestone
in our company's history by ringing the Nasdaq closing bell," said Mr. Domzalski. "Our
new name and brand will unify our history with our future ambitions as a leading company in the dermatology space."
"Having achieved FDA approval for our two commercial products
AMZEEQ and ZILXI in a period of less than eight months is a testament to the value of our proprietary
technology and is aligned to the symbolic meaning behind our new name strength, growth, endurance, and resilience, "
continued Mr. Domzalski. "We are focused on growing the business, building our franchise in a way that will maximize our
operational capabilities, and developing a pipeline of innovative products to address unmet needs for patients."
The corporate name change to VYNE does not affect the rights
of the Company's stockholders and no action is required by stockholders with respect to the name change. The Company's
common stock has been assigned a new CUSIP number of 92941V 100. The number of outstanding shares of the Company's common
stock is not affected by the name and ticker change.
About VYNE Therapeutics Inc.
VYNE Therapeutics' mission is to improve the lives of
patients by developing proprietary, innovative and differentiated therapies in dermatology and beyond.
520 US Highway 22 - 2nd
Floor - Bridgewater, NJ 08807
With expertise in topical medicine innovation as a springboard,
VYNE is working to develop and commercialize a variety of solutions using its proprietary Molecule Stabilizing Technology (MST ),
and has received FDA approval for AMZEEQ (minocycline) topical foam, 4%, the world's first topical minocycline, and
for ZILXI (minocycline) topical foam, 1.5%, the first minocycline product of any kind to be approved by the FDA for use
in rosacea. For more information about our approved products, please see AMZEEQ's Full Prescribing Information at amzeeq.com
and ZILXI's Full Prescribing Information at zilxi.com.
For more information about VYNE Therapeutics Inc. or its investigational
products, visit www. vynetherapeutics.com or follow VYNE on Twitter. VYNE may use its website to comply with its disclosure
obligations under Regulation FD. Therefore, investors should monitor VYNE's website in addition to following its press releases,
filings with the U.S. Securities and Exchange Commission, public conference calls, and webcasts.
LifeSci Advisors, LLC
Chief Financial Officer
520 US Highway 22 - 2nd
Floor - Bridgewater, NJ 08807
Cautionary Statement Regarding Forward-Looking Statements
This release includes forward-looking statements within
the meaning of the Private Securities Litigation Reform Act of 1995, including, but not limited to, statements regarding the
development and commercialization of VYNE's products and product candidates and other statements regarding the future
expectations, plans and prospects of VYNE. All statements in this press release which are not historical facts are
forward-looking statements. Any forward-looking statements are based on VYNE's current knowledge and its present
beliefs and expectations regarding possible future events and are subject to risks, uncertainties and assumptions that could
cause actual results to differ materially and adversely from those set forth or implied by such forward-looking statements.
These risks and uncertainties include, but are not limited to: the COVID-19 pandemic and its impact on our business
operations; adverse events associated with the commercialization of AMZEEQ and ZILXI; the outcome and cost of clinical trials
for current and future product candidates; determination by the FDA that results from VYNE's clinical trials are not
sufficient to support registration or marketing approval of product candidates; the outcome of pricing, coverage and
reimbursement negotiations with third party payors for AMZEEQ, ZILXI or any other products or product candidates that VYNE
may commercialize in the future; whether, and to what extent, third party payors impose additional requirements before
approving AMZEEQ and ZILXI prescription reimbursement; the eligible patient base and commercial potential of AMZEEQ, ZILXI or
any of VYNE's other products or product candidates; risks that VYNE's intellectual property rights, such as
patents, may fail to provide adequate protection, may be challenged and one or more claims may be revoked or interpreted
narrowly or will not be infringed; risks that any of VYNE's patents may be held to be narrowed, invalid or
unenforceable or one or more of VYNE's patent applications may not be granted and potential competitors may also seek
to design around VYNE's granted patents or patent applications; additional competition in the acne and dermatology
markets; risks related to our indebtedness; inability to raise additional capital on favorable terms or at all; VYNE's
ability to recruit and retain key employees; and VYNE's ability to stay in compliance with applicable laws, rules and
regulations. For a discussion of other risks and uncertainties, and other important factors, any of which could cause
VYNE's actual results to differ from those contained in the forward-looking statements, see the section titled
"Risk Factors" in VYNE's Quarterly Report on Form 10-Q for the quarter ended March 31, 2020, as well as
discussions of potential risks, uncertainties, and other important factors in VYNE's subsequent filings with the U.S.
Securities and Exchange Commission. Although VYNE believes these forward-looking statements are reasonable, they speak only
as of the date of this announcement and VYNE undertakes no obligation to update publicly such forward-looking statements to
reflect subsequent events or circumstances, except as otherwise required by law. Given these risks and uncertainties, you
should not rely upon forward-looking statements as predictions of future events.
520 US Highway 22 - 2nd
Floor - Bridgewater, NJ 08807
Last updated: Sep 8, 2020