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Verrica Pharmaceuticals Announces Acceptance of Late-Breaking Abstract Highlighting Potential Abscopal Effect of VP-315 for the Treatment of Basal Cell Carcinoma at the Upcoming 2026 Society for Investigative Dermatology Annual Meeting

Key Takeaway: Verrica Pharmaceuticals announced the acceptance of a late-breaking abstract for VP-315, an oncolytic peptide, at the 2026 Society for Investigative Dermatology Annual Meeting. The abstract highlights Phase 2 exploratory data suggesting a potential abscopal effect in treating basal cell carcinoma. This presentation underscores the importance of VP-315 as a promising non-surgical option for patients.
Price reaction · baseline $5.83 (2026-04-09 close) · hit pre-market · clean, no other VRCA news in the window
day 0 close · peak
-12.3%
day 1
-3.6%
day 3
+1.4%

Market Sentiment Analysis

POSITIVE FACTORS

  • VP-315 shows potential as a non-surgical treatment option.
  • The upcoming presentation at a prestigious dermatology meeting highlights its significance.
  • There is a high unmet need for new treatments for basal cell carcinoma.

BiopharmaWatch Analysis

From our catalyst data and publicly available data · not financial advice
Best trade, last catalyst
+177%
120-day peak, hindsight
Typical move
24.2%
average across 7 past catalysts
Cash runway
~3 mo
High dilution risk
Lead asset
Part 1: VP-315 3 Day Dosing/Week
Phase 2 · Basal Cell Carcinoma

Full Press Release Details

WEST CHESTER, Pa., April 09, 2026(GLOBE NEWSWIRE)-- Verrica Pharmaceuticals Inc. (“Verrica”) (Nasdaq: VRCA), a therapeutics company developing and commercializing medications for the treatment of dermatological diseases, including skin cancers, today announced acceptance of a late-breaking abstract reporting Phase 2 exploratory data of VP-315, Verrica’s novel oncolytic peptide for the treatment of basal cell carcinoma. The data will be presented at the upcoming 2026 Society for Investigative Dermatology (SID) Annual Meeting, which will take place from May 13-16, 2026, in Chicago, Illinois.

Presentation Details:

Title:“VP-315 Demonstrates Potential Abscopal Effect in Untreated Non-Target Basal Cell Carcinoma (BCC) Tumors”

Poster Number: LB1190
Category: Non-Melanoma Cancers and UV Biology/Injury
Poster Session Dates and Time:
Friday, May 15, 2026 (4:30 pm – 6:00 pm)
Location: (Salons B,C,D - Lower Level, Hilton Chicago)
About VP- 315 (ruxotemitide)VP-315 is a potential first-in-class oncolytic chemotherapeutic peptide immunotherapy administered directly into a tumor to induce immunogenic cell death and thereby unleashing a broad spectrum of tumor antigens for T cell responses, which may offer a non-surgical option for patients suffering from skin cancer. Verrica holds an exclusive worldwide license to develop and commercialize VP-315 for certain dermatologic oncology indications, including non-metastatic melanoma and non-metastatic merkel cell carcinoma, and intends to focus initially on basal cell and squamous cell carcinomas as the lead indications for development. VP-315 has demonstrated positive tumor-specific immune cell responses in multi-indication Phase 1/2 oncology trials.
About Basal Cell CarcinomaBasal cell carcinoma is the most common form of cancer in the U.S., and incidence is rising worldwide. There are approximately 3.6 million diagnoses of basal cell carcinomas in the U.S. each year, with a high unmet need for new treatment options. Basal cell carcinoma is generally treated with invasive surgery to remove the tumor, which can cause pain, infection, bleeding and scarring.
About Verrica Pharmaceuticals Inc.Verrica is a therapeutics company developing and commercializing medications for the treatment of dermatological diseases, including skin cancer. Verrica’s product YCANTH®(VP-102) (cantharidin), is the first and only healthcare professional-administered treatment approved by the FDA to treat adult and pediatric patients two years of age and older with molluscum contagiosum, a highly contagious viral skin infection affecting approximately 6 million people in the United States, primarily children. YCANTH®(VP-102) is also in development to treat common warts, the largest remaining unmet need in medical dermatology. Verrica has also entered a worldwide license agreement with Lytix Biopharma AS to develop and commercialize VP-315 (ruxotemitide, formerly known as LTX-315 and VP-LTX-315) for non-melanoma skin cancers including basal cell carcinoma and squamous cell carcinoma.  For more information, visitwww.verrica.com.
Forward-Looking StatementsAny statements contained in this press release that do not describe historical facts may constitute forward-looking statements as that term is defined in the Private Securities Litigation Reform Act of 1995. These statements may be identified by words such as “believe,” “expect,” “may,” “plan,” “potential,” “will,” and similar expressions, and are based on Verrica’s current beliefs and expectations. These forward-looking statements include statements about the clinical development and benefits of Verrica’s product candidates, including VP-315. These statements involve risks and uncertainties that could cause actual results to differ materially from those reflected in such statements. Risks and uncertainties that may cause actual results to differ materially include risks and uncertainties related to market conditions, satisfaction of customary closing conditions related to the proposed public offering and other risks and uncertainties that are described in Verrica’s Annual Report on Form 10-K for the year ended December 31, 2025 and other filings Verrica makes with the SEC. Any forward-looking statements speak only as of the date of this press release and are based on information available to Verrica as of the date of this release, and Verrica assumes no obligation to, and does not intend to, update any forward-looking statements, whether as a result of new information, future events or otherwise.

John KirbyInterim Chief Financial Officerjkirby@verrica.com

Frequently Asked Questions

What is VP-315?

VP-315 is a novel oncolytic peptide developed by Verrica for treating basal cell carcinoma.

When will the VP-315 data be presented?

The data will be presented at the 2026 Society for Investigative Dermatology Annual Meeting from May 13-16.

What is the significance of the abscopal effect?

The abscopal effect refers to a phenomenon where localized treatment leads to systemic anti-tumor responses.

Why is there a need for new treatments for basal cell carcinoma?

Basal cell carcinoma is the most common cancer in the U.S., with rising incidence and limited treatment options.

Last updated: Apr 10, 2026