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Upstream Bio to Present at the 44th Annual J.P. Morgan Healthcare Conference

Key Takeaway: Upstream Bio, a clinical-stage biotechnology firm, announced that CEO Rand Sutherland will present at the 44th Annual J.P. Morgan Healthcare Conference on January 12, 2026. The company focuses on developing treatments for inflammatory diseases, particularly severe respiratory disorders. Their lead product, verekitug, is in Phase 2 trials for several conditions, including chronic rhinosinusitis and severe asthma.
Price reaction · baseline $27.07 (2026-01-02 close) · hit pre-market · clean, no other UPB news in the window
day 0 close · peak
-3.5%

Market Sentiment Analysis

POSITIVE FACTORS

  • Upstream Bio is advancing innovative treatments for inflammatory diseases.
  • The presentation at a prestigious conference highlights company visibility.
  • Verekitug targets a significant unmet medical need in respiratory disorders.

BiopharmaWatch Analysis

From our catalyst data and publicly available data · not financial advice
Best trade, last catalyst
+35%
120-day peak, hindsight
Typical move
17.4%
average across 4 past catalysts
Cash runway
~22 mo
Low dilution risk
Lead asset
Verekitug
Phase 2 · Chronic Obstructive Pulmonary Disease

Full Press Release Details

WALTHAM, Mass., Jan. 05, 2026 (GLOBE NEWSWIRE) --Upstream Bio, Inc.(Nasdaq: UPB), a clinical-stage company developing treatments for inflammatory diseases, with an initial focus on severe respiratory disorders, today announced that Rand Sutherland, MD, Chief Executive Officer of Upstream Bio, will be presenting at the 44thAnnual J.P. Morgan Healthcare Conference on Monday, January 12, 2026, at 2:15 p.m. PT.
A live webcast of the presentation will be available under theEventstab on the Investors section of Upstream Bio’s website on the day of the event. A replay will be available on the Company's website following the presentation.
About Upstream BioUpstream Bio is a clinical-stage biotechnology company developing treatments for inflammatory diseases, with an initial focus on severe respiratory disorders. Upstream Bio is developing verekitug, the only known antagonist currently in clinical development that targets the receptor for thymic stromal lymphopoietin (TSLP), a cytokine which is a clinically validated driver of inflammatory response positioned upstream of multiple signaling cascades that affect a variety of immune mediated diseases. Upstream Bio has advanced this highly potent monoclonal antibody into separate Phase 2 trials for the treatment of chronic rhinosinusitis with nasal polyps (CRSwNP), severe asthma and chronic obstructive pulmonary disease (COPD). Upstream Bio’s team is committed to maximizing verekitug’s unique attributes to address the substantial unmet needs for patients underserved by today’s standard of care. To learn more, please visitwww.upstreambio.com.

Investor and Media Contact:Meggan BuckwellDirector, Corporate Communications and Investor Relationsir@upstreambio.com

Frequently Asked Questions

When is Upstream Bio's presentation at the conference?

The presentation is scheduled for January 12, 2026, at 2:15 p.m. PT.

What is verekitug used for?

Verekitug is developed for treating inflammatory diseases, focusing on severe respiratory disorders.

Where can I watch the presentation?

A live webcast will be available on Upstream Bio's website under the Events tab.

What conditions is Upstream Bio targeting with verekitug?

Verekitug is in Phase 2 trials for chronic rhinosinusitis, severe asthma, and COPD.

Last updated: Jan 5, 2026