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Upstream Bio to Participate in Upcoming December Investor Conferences

Key Takeaway: Upstream Bio, Inc. has announced its participation in several investor conferences scheduled for December. CEO Rand Sutherland will represent the company, which is focused on developing treatments for inflammatory diseases, particularly severe respiratory disorders. The company is advancing its monoclonal antibody, verekitug, into Phase 2 trials for various conditions, including chronic rhinosinusitis and severe asthma.
Price reaction · baseline $26.05 (2025-11-24 close) · hit pre-market · clean, no other UPB news in the window
day 0 close
+10.7%
day 1
+7.5%
day 3 · peak
+11.2%

Market Sentiment Analysis

POSITIVE FACTORS

  • Participation in multiple investor conferences indicates strong investor interest.
  • CEO Rand Sutherland's involvement highlights leadership engagement.
  • Focus on innovative treatments for severe respiratory disorders shows commitment to addressing unmet medical needs.

BiopharmaWatch Analysis

From our catalyst data and publicly available data · not financial advice
Best trade, last catalyst
+35%
120-day peak, hindsight
Typical move
17.4%
average across 4 past catalysts
Cash runway
~22 mo
Low dilution risk
Lead asset
Verekitug
Phase 2 · Chronic Obstructive Pulmonary Disease

Full Press Release Details

WALTHAM, Mass., Nov. 25, 2025 (GLOBE NEWSWIRE) --Upstream Bio, Inc.(Nasdaq: UPB), a clinical-stage company developing treatments for inflammatory diseases, with an initial focus on severe respiratory disorders, today announced that Rand Sutherland, MD, Chief Executive Officer of Upstream Bio, will be participating in the following upcoming investor conferences in December:
Live webcasts of the presentations will be available under theEventstab on the Investors section of Upstream Bio’s website on the day of the event. A replay of the webcasts will be posted on the Company's website following the presentations.
About Upstream BioUpstream Bio is a clinical-stage biotechnology company developing treatments for inflammatory diseases, with an initial focus on severe respiratory disorders. Upstream Bio is developing verekitug, the only known antagonist currently in clinical development that targets the receptor for thymic stromal lymphopoietin (TSLP), a cytokine which is a clinically validated driver of inflammatory response positioned upstream of multiple signaling cascades that affect a variety of immune mediated diseases. Upstream Bio has advanced this highly potent monoclonal antibody into separate Phase 2 trials for the treatment of chronic rhinosinusitis with nasal polyps (CRSwNP), severe asthma and chronic obstructive pulmonary disease (COPD). Upstream Bio’s team is committed to maximizing verekitug’s unique attributes to address the substantial unmet needs for patients underserved by today’s standard of care. To learn more, please visitwww.upstreambio.com.

Investor and Media Contact:Meggan BuckwellDirector, Corporate Communications and Investor Relationsir@upstreambio.com

Frequently Asked Questions

Who will represent Upstream Bio at the conferences?

CEO Rand Sutherland will represent Upstream Bio at the upcoming conferences.

What is the focus of Upstream Bio's treatments?

Upstream Bio focuses on developing treatments for inflammatory diseases, especially severe respiratory disorders.

What is verekitug?

Verekitug is a monoclonal antibody targeting TSLP, currently in Phase 2 trials for various respiratory conditions.

Where can I watch the conference presentations?

Live webcasts of the presentations will be available on Upstream Bio's website.

Last updated: Nov 25, 2025