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10x Genomics Reports Third Quarter 2026 Financial Results

Key Takeaway: 10x Genomics reported a revenue of $150.7 million for Q3 2026, marking a 1% increase from the previous year. The company successfully launched Atera, which has seen strong demand. Despite a gross margin improvement to 75%, 10x Genomics reported an operating loss of $16.1 million and a net loss of $19.4 million.

Market Sentiment Analysis

POSITIVE FACTORS

  • Revenue increased by 1% year-over-year.
  • Successful launch of Atera with high demand.
  • Gross margin improved to 75%.

CONCERNS & RISKS

  • Operating loss of $16.1 million reported.
  • Net loss of $19.4 million for the quarter.

Full Press Release Details

PLEASANTON, Calif., Nov. 5, 2026 /PRNewswire/ -- 10x Genomics, Inc. (Nasdaq: TXG), the life science technology leader focused on accelerating science and advancing human health, today reported financial results for the third quarter ended September 30, 2026.

Recent Updates

• Revenue was $150.7 million for the third quarter of 2026, representing a 1% increase over the corresponding period of 2025.
• Began global commercial shipments of Atera, with extraordinary early demand translating into ambitious new research programs spanning discovery, translational and biopharma research.
• Introduced Sentira, a cloud analysis platform to help customers turn complex biological datasets into insights, powered by NVIDIA accelerated computing for spatial data processing and Anthropic's Claude for agentic AI analysis of single cell data.
"The biggest highlight of the quarter was the start of commercial shipments of Atera. Enthusiasm for the platform has continued to build, and we are incredibly excited to be putting instruments in customers' hands. We were also encouraged with the results across our broader business, driven by continued strength in consumables," said Serge Saxonov, Co-founder and CEO of 10x Genomics. "As biology is entering a new era of AI and data maximalism, 10x is positioned incredibly well to benefit and to be the key enabler of progress going forward."

Third Quarter 2026 Financial Results

Revenue was $150.7 million for the third quarter of 2026, as compared to $149.0 million for the corresponding period of 2025. Revenue increased 1% over the corresponding period of 2025.
Gross margin was 75% for the third quarter of 2026, as compared to 67% for the corresponding prior year period. The increase in gross margin was primarily due to lower inventory write-downs and changes in product mix.
Operating expenses were $129.0 million for the third quarter of 2026, a 3% decrease from $132.5 million for the corresponding prior year period. The decrease was primarily driven by lower personnel and lab equipment expenses, partially offset by higher litigation expenses.
Operating loss was $16.1 million for the third quarter of 2026, as compared to operating loss of $32.2 million for the corresponding prior year period.
Net loss was $19.4 million for the third quarter of 2026, as compared to net loss of $27.5 million for the corresponding prior year period.
Cash and cash equivalents and marketable securities were $575.7 million as of September 30, 2026.

2026 Financial Guidance

10x Genomics is raising its full year 2026 revenue guidance and now expects revenue in the range of $625 million to $635 million, versus the previous range of $610 million to $630 million. Excluding the non-recurring license and royalty revenue related to patent litigation settlements in both 2026 and 2025, this represents 4% to 6% growth over full year 2025.

Webcast and Conference Call Information

10x Genomics will host a conference call to discuss the third quarter 2026 financial results, business developments and outlook after market close on Thursday, November 5, 2026 at 1:30 PM Pacific Time / 4:30 PM Eastern Time. A webcast of the conference call can be accessed at http://investors.10xgenomics.com. The webcast will be archived and available for replay at least 45 days after the event.

About 10x Genomics

10x Genomics is a life science technology company building products to accelerate the mastery of biology and advance human health. Our integrated research solutions include instruments, consumables and software for single cell and spatial biology, which help academic and translational researchers and biopharmaceutical companies understand biological systems at a resolution and scale that matches the complexity of biology. Our products are behind breakthroughs in oncology, immunology, neuroscience and more, fueling powerful discoveries that are transforming the world's understanding of health and disease. To learn more, visit 10xgenomics.com or connect with us on LinkedIn, X, Facebook, Bluesky or YouTube.

Forward Looking Statements

This press release contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995 as contained in Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, as amended, which are subject to the "safe harbor" created by those sections. All statements included in this press release, other than statements of historical facts, may be forward-looking statements. Forward-looking statements generally can be identified by the use of forward-looking terminology such as "may," "might," "will," "should," "expect," "plan," "outlook," "anticipate," "could," "intend," "target," "project," "contemplate," "believe," "see," "estimate," "predict," "potential," "would," "likely," "seek" or "continue" or the negatives of these terms or variations of them or similar terminology, but the absence of these words does not mean that a statement is not forward-looking. These forward-looking statements include statements regarding 10x Genomics, Inc.'s products, services, business strategy, collaborations and opportunities; the commercial launch of, demand for and customer adoption of Atera; the capabilities, availability and expected benefits of Sentira, including its use of third-party accelerated computing and artificial intelligence technologies; the role of artificial intelligence in advancing biological research and 10x Genomics, Inc.'s ability to benefit from that trend; continued demand for consumables; and 10x Genomics, Inc.'s financial performance and results of operations, including expectations regarding revenue, revenue growth and guidance. These statements are based on management's current expectations, forecasts, beliefs, estimates, assumptions and information currently available to management. Actual outcomes and results could differ materially from these statements due to a number of factors and such statements should not be relied upon as representing 10x Genomics, Inc.'s views as of any date subsequent to the date of this press release. 10x Genomics, Inc. disclaims any obligation to update any forward-looking statements provided to reflect any change in 10x Genomics' expectations or any change in events, conditions or circumstances on which any such statement is based, except as required by law. The material risks and uncertainties that could affect 10x Genomics, Inc.'s financial and operating results and cause actual results to differ materially from those indicated by the forward-looking statements made in this press release include those discussed under the captions "Risk Factors" and "Management's Discussion and Analysis of Financial Condition and Results of Operations" in the company's most recently-filed 10-K for the fiscal year ended December 31, 2025 filed on February 12, 2026 and the company's quarterly report on Form 10-Q for the quarter ended September 30, 2026 to be filed with the U.S. Securities and Exchange Commission ("SEC"), and elsewhere in the documents 10x Genomics, Inc. files with the SEC from time to time.

Disclosure Information

10x Genomics uses filings with the Securities and Exchange Commission, its website (www.10xgenomics.com), press releases, public conference calls, public webcasts and its social media accounts as means of disclosing material non-public information and for complying with its disclosure obligations under Regulation FD.
10x Genomics, Inc. Condensed Consolidated Statements of Operations (Unaudited) (In thousands, except share and per share data)
Three Months Ended September 30, Nine Months Ended September 30,
2026 2025 2026 2025
Products and services revenue $ 150,210 $ 148,019 $ 449,200 $ 430,999
License and royalty revenue 457 983 3,346 45,794
Revenue (1) 150,667 149,002 452,546 476,793
Cost of products and services revenue (2) 37,740 48,695 120,944 145,957
Gross profit 112,927 100,307 331,602 330,836
Operating expenses:
Research and development (2) 52,929 57,194 166,567 182,663
Selling, general and administrative (2) 76,055 75,355 221,093 239,517
Gain on settlement — — (3,400) (49,900)
Total operating expenses 128,984 132,549 384,260 372,280
Loss from operations (16,057) (32,242) (52,658) (41,444)
Other income (expense):
Interest income 5,018 5,199 14,829 13,156
Interest expense — 3 — —
Other income (expense), net (7,437) (1,165) (12,139) 3,574
Total other income (expense) (2,419) 4,037 2,690 16,730
Loss before provision for income taxes (18,476) (28,205) (49,968) (24,714)
Provision for (benefit from) income taxes 949 (733) 858 2,578
Net loss $ (19,425) $ (27,472) $ (50,826) $ (27,292)
Net loss per share, basic and diluted $ (0.15) $ (0.22) $ (0.39) $ (0.22)
Weighted-average shares used to compute net loss per share, basic and diluted 130,805,838 125,502,291 129,570,736 123,965,205
(1) The following table represents total revenue by source for the periods indicated (in thousands). Spatial includes the Company's Visium, Xenium and Atera products:
Three Months Ended September 30, Nine Months Ended September 30,
2026 2025 2026 2025
Instruments
Single Cell $ 3,782 $ 4,927 $ 12,092 $ 16,567
Spatial 3,076 7,072 13,689 24,744
Total instruments revenue 6,858 11,999 25,781 41,311
Consumables
Single Cell 93,139 92,519 270,484 262,416
Spatial 41,188 35,373 124,396 103,017
Total consumables revenue 134,327 127,892 394,880 365,433
Services 9,025 8,128 28,539 24,255
Products and services revenue 150,210 148,019 449,200 430,999
License and royalty revenue 457 983 3,346 45,794
Total revenue $ 150,667 $ 149,002 $ 452,546 $ 476,793
(1) The following table presents revenue by geography based on the location of the customer for the periods indicated (in thousands):
Three Months Ended September 30, Nine Months Ended September 30,
2026 2025 2026 2025
Americas
United States* $ 82,093 $ 77,246 $ 240,895 $ 267,555
Americas (excluding United States) 3,849 2,625 10,172 9,044
Total Americas 85,942 79,871 251,067 276,599
Europe, Middle East and Africa 38,753 41,624 115,577 108,253
Asia-Pacific
China 15,216 15,189 46,021 55,242
Asia-Pacific (excluding China) 10,756 12,318 39,881 36,699
Total Asia-Pacific 25,972 27,507 85,902 91,941
Total revenue $ 150,667 $ 149,002 $ 452,546 $ 476,793
* Includes license and royalty revenue.
(2) Includes stock-based compensation expense as follows:
Three Months Ended September 30, Nine Months Ended September 30,
(in thousands) 2026 2025 2026 2025
Cost of revenue $ 2,157 $ 2,011 $ 5,911 $ 6,481
Research and development 8,940 11,318 30,168 38,037
Selling, general and administrative 11,999 11,935 35,275 39,067
Total stock-based compensation expense $ 23,096 $ 25,264 $ 71,354 $ 83,585
10x Genomics, Inc. Condensed Consolidated Balance Sheets (Unaudited) (In thousands)
September 30, 2026 December 31, 2025
Assets
Current assets:
Cash and cash equivalents $ 526,187 $ 473,966
Marketable securities 49,493 49,443
Accounts receivable, net 55,701 47,013
Other receivables 3,055 35,480
Inventory 64,629 56,341
Prepaid expenses and other current assets 19,566 22,208
Total current assets 718,631 684,451
Property and equipment, net 210,239 226,711
Operating lease right-of-use assets 54,759 60,450
Goodwill 6,918 4,511
Intangible assets, net 58,663 62,329
Other noncurrent assets 13,919 2,913
Total assets $ 1,063,129 $ 1,041,365
Liabilities and stockholders' equity
Current liabilities:
Accounts payable $ 21,594 $ 12,733
Accrued compensation and related benefits 39,657 42,500
Accrued expenses and other current liabilities 32,181 39,971
Deferred revenue 22,956 23,902
Operating lease liabilities 11,946 10,985
Contingent consideration, current 12,036 23,363
Total current liabilities 140,370 153,454
Contingent consideration, noncurrent 5,842 1,237
Operating lease liabilities, noncurrent 63,846 73,376
Deferred revenue, noncurrent 8,530 10,501
Other noncurrent liabilities 6,505 6,471
Total liabilities 225,093 245,039
Stockholders' equity:
Preferred stock — —
Common stock 2 2
Additional paid-in capital 2,399,254 2,306,690
Accumulated deficit (1,561,417) (1,510,591)
Accumulated other comprehensive income 197 225
Total stockholders' equity 838,036 796,326
Total liabilities and stockholders' equity $ 1,063,129 $ 1,041,365

Frequently Asked Questions

What was 10x Genomics' revenue for Q3 2026?

10x Genomics reported revenue of $150.7 million for Q3 2026.

How did Atera perform after its launch?

Atera experienced extraordinary early demand and new research programs.

What was the operating loss for Q3 2026?

The operating loss for Q3 2026 was $16.1 million.

What is the updated revenue guidance for 2026?

The updated revenue guidance is between $625 million and $635 million.

Last updated: Nov 5, 2026